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2017, Advances in experimental medicine and biology, ISBN 9811032335, Volume 962, xx, 515 pages
This volume provides the reader with an overview of the diverse functions of the RUNX family of genes. As highlighted in the introduction and several of the 29... 
physiology | Core Binding Factor Alpha 1 Subunit | Life sciences | Research | DNA-binding proteins | Neoplasms | Cell Growth Processes | Cancer | etiology | Biochemistry | Proteins
Book
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 6/2014, Volume 111, Issue 23, pp. 8482 - 8487
The pathogenesis of cleidocranial dysplasia (CCD) as well as the specific role of core binding factor β (Cbfβ... 
Phenotypes | Bone formation | Chondrocytes | Bones | Skull | Skeletal development | Mice | Promoter regions | Epiphyses | Osteoblasts | Endochondral bone formation | Growth plate formation | Chondrocyte differentiation | Ossification | Osteoblast differentiation | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Osteogenesis - physiology | Protein Multimerization | Core Binding Factor beta Subunit - genetics | Mice, 129 Strain | Core Binding Factor Alpha 1 Subunit - metabolism | Promoter Regions, Genetic - genetics | Collagen Type I - genetics | Chondrocytes - physiology | Gene Expression Regulation, Developmental | Cleidocranial Dysplasia - physiopathology | Cleidocranial Dysplasia - metabolism | Chondrocytes - metabolism | Osteogenesis - genetics | Core Binding Factor beta Subunit - metabolism | Animals, Newborn | Skull - metabolism | Collagen Type I - metabolism | Mice, Inbred C57BL | Osteoblasts - physiology | Cells, Cultured | Activating Transcription Factor 4 - genetics | Core Binding Factor beta Subunit - physiology | Mice, Transgenic | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Transcription Factors - metabolism | Microscopy, Confocal | Animals | Activating Transcription Factor 4 - metabolism | Cleidocranial Dysplasia - genetics | Skull - cytology | Sp7 Transcription Factor | Protein Binding | Osteoblasts - metabolism | Core Binding Factor Alpha 1 Subunit - genetics | Microscopy, Fluorescence | Index Medicus | Biological Sciences | ossification | endochondral bone formation | growth plate formation | osteoblast differentiation | chondrocyte differentiation
Journal Article
Journal Article
Leukemia, ISSN 0887-6924, 2012, Volume 26, Issue 8, pp. 1829 - 1841
Journal Article
Cell cycle (Georgetown, Tex.), ISSN 1538-4101, 05/2012, Volume 11, Issue 10, pp. 1938 - 1947
Journal Article
Journal Article
The international journal of biochemistry & cell biology, ISSN 1357-2725, 11/2019, Volume 116, pp. 105597 - 105597
•RA inhibits differentiation and mineralization of MC-3T3 pre-osteoblasts.•RA increases the expression of the osteogenic lineage factor RunX2... 
WNT signaling | Retinoic acid | Osteogenesis | Osteoblast mineralization | Osteoblast differentiation | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Humans | Lymphoid Enhancer-Binding Factor 1 - genetics | Alkaline Phosphatase - metabolism | Core Binding Factor Alpha 1 Subunit - antagonists & inhibitors | Wnt Proteins - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Low Density Lipoprotein Receptor-Related Protein-6 - genetics | Wnt Proteins - genetics | Cell Differentiation | Osteoblasts - cytology | Osteogenesis - genetics | Tretinoin - pharmacology | Calcification, Physiologic - genetics | Cell Line | Alkaline Phosphatase - genetics | Calcification, Physiologic - drug effects | Osteoblasts - drug effects | Osteogenesis - drug effects | Intercellular Signaling Peptides and Proteins - genetics | Lymphoid Enhancer-Binding Factor 1 - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Gene Expression Regulation - drug effects | Low Density Lipoprotein Receptor-Related Protein-6 - metabolism | Animals | Wnt Signaling Pathway - drug effects | Wnt Signaling Pathway - genetics | Anthraquinones | Sp7 Transcription Factor - genetics | Low Density Lipoprotein Receptor-Related Protein-5 - metabolism | Sp7 Transcription Factor - metabolism | Mice | Proto-Oncogene Proteins c-myc - genetics | Osteoblasts - metabolism | Core Binding Factor Alpha 1 Subunit - genetics | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 10/2010, Volume 107, Issue 46, pp. 19879 - 19884
.... How expression of bone-related miRs is regulated remains a compelling question. Here we report that Runx2, a transcription factor essential for osteoblastogenesis, negatively regulates expression of the miR cluster 23a∼27a∼24-2... 
Untranslated regions | Phenotypes | MicroRNA | Bone formation | Messenger RNA | Osteocytes | Gene expression regulation | Down regulation | Osteoblasts | Binding sites | Bone formation by miRs | Runx2-regulation of microRNA cluster phenotype attenuation by miRs | Feed forward-feedback miR control SATB2 targeted by cluster miRs | Multigene Family | Matrix Attachment Region Binding Proteins - metabolism | Rats | MicroRNAs - metabolism | Transcription Factors - genetics | Gene Regulatory Networks | Core Binding Factor Alpha 1 Subunit - metabolism | Down-Regulation - genetics | Transcription Factors - metabolism | Cell Differentiation - genetics | Feedback, Physiological | Animals | Matrix Attachment Region Binding Proteins - genetics | Protein Binding | Mice | MicroRNAs - genetics | Osteoblasts - cytology | Osteoblasts - metabolism | Binding Sites | Core Binding Factor Alpha 1 Subunit - genetics | Osteogenesis - genetics | Repressor Proteins - metabolism | Transcription factors | Growth | Physiological aspects | Bones | Genetic aspects | Research | Cell differentiation | Index Medicus | Biological Sciences | Runx2-regulation of microRNA cluster | SATB2 targeted by cluster miRs | feed forward-feedback miR control | bone formation by miRs | phenotype attenuation by miRs
Journal Article