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Molecular Cell, ISSN 1097-2765, 02/2013, Volume 49, Issue 4, pp. 632 - 644
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 500, Issue 7460, pp. 93 - 97
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2006, Volume 12, Issue 8, pp. 945 - 949
Journal Article
Science, ISSN 0036-8075, 8/2011, Volume 333, Issue 6043, pp. 765 - 769
The chromosomal translocations found in acute myelogenous leukemia (AML) generate oncogenic fusion transcription factors with aberrant transcriptional... 
Cell growth | Myeloid leukemia | Leukemia | Genes | REPORTS | Antibodies | Histones | Amino acids | Acetylation | Leukocytes | Cells | DNA-BINDING | DOMAIN | MULTIDISCIPLINARY SCIENCES | HEMATOPOIETIC STEM-CELLS | T(8/21) | TRANSCRIPTION | FUSION PROTEIN | MYELOID-LEUKEMIA | SELF-RENEWAL | DIFFERENTIATION | INHIBITOR | Oncogene Proteins, Fusion - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Transcriptional Activation | Preleukemia - pathology | E1A-Associated p300 Protein - metabolism | Gene Expression Profiling | Oncogene Proteins, Fusion - chemistry | Core Binding Factor Alpha 2 Subunit - chemistry | E1A-Associated p300 Protein - antagonists & inhibitors | Hematopoietic Stem Cells - physiology | Lysine - metabolism | Protein Interaction Domains and Motifs | Tumor Cells, Cultured | Cell Line | Core Binding Factor Alpha 2 Subunit - metabolism | Leukemia, Myeloid, Acute - pathology | Mice, Inbred C57BL | Mutant Proteins - metabolism | Fetal Blood - cytology | RUNX1 Translocation Partner 1 Protein | Preleukemia - metabolism | Animals | Cell Transformation, Neoplastic | Hematopoietic Stem Cells - cytology | Cell Line, Tumor | Protein Binding | Mice | Protein Processing, Post-Translational | Genetic aspects | Research | Lysine | Health aspects | Cancer cells | Proteins | Biochemistry | Cellular biology | Chromosomes | Rope | Mathematical models | Transformations | Leukemias | Blood | Index Medicus
Journal Article
Genome Research, ISSN 1088-9051, 11/2016, Volume 26, Issue 11, pp. 1468 - 1477
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 9, pp. 4732 - 4741
AML1-ETO is the most common fusion oncoprotein causing acute myeloid leukemia (AML), a disease with a 5-year survival rate of only 24%. AML1-ETO functions as a... 
COMPLEX | DOMAIN | CCT | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | INTRANUCLEAR MOBILITY | ACUTE MYELOID-LEUKEMIA | EUKARYOTIC CHAPERONIN | CYTOPLASMIC CHAPERONIN | PROTEINS | TRANSCRIPTION FACTOR | Protein Subunits | Oncogene Proteins, Fusion - metabolism | Immunoprecipitation | Humans | Gene Expression Regulation, Neoplastic | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Recombinant Fusion Proteins - metabolism | Oncogene Proteins, Fusion - chemistry | Core Binding Factor Alpha 2 Subunit - chemistry | Cattle | HEK293 Cells | Protein Interaction Domains and Motifs | Protein Stability | Chaperonin Containing TCP-1 - metabolism | Peptide Fragments - genetics | Peptide Fragments - metabolism | Core Binding Factor Alpha 2 Subunit - metabolism | Cell Survival | Models, Molecular | Rats | Neoplasm Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Reticulocytes - metabolism | Protein Folding | HSP70 Heat-Shock Proteins - metabolism | RUNX1 Translocation Partner 1 Protein | Peptide Fragments - chemistry | Animals | Chaperonin Containing TCP-1 - antagonists & inhibitors | Oncogene Proteins, Fusion - genetics | Protein Conformation | Chaperonin Containing TCP-1 - chemistry | Core Binding Factor Alpha 2 Subunit - genetics | Index Medicus | AML1-ETO | Protein Structure and Folding | leukemia | fusion protein | chaperone | chaperonin | protein folding | TRiC
Journal Article
Leukemia, ISSN 0887-6924, 2009, Volume 23, Issue 8, pp. 1426 - 1431
Journal Article
Genes and Development, ISSN 0890-9369, 03/2008, Volume 22, Issue 5, pp. 640 - 653
Journal Article
Cell, ISSN 0092-8674, 06/2018, Volume 174, Issue 1, pp. 172 - 186.e21
The fusion oncoprotein CBFβ-SMMHC, expressed in leukemia cases with chromosome 16 inversion, drives leukemia development and maintenance by altering the... 
enhancer | acute myeloid leukemia | MYC | chromatin | Runx1 | CBFbeta | CBFb-SMMHC | TRANSCRIPTION FACTORS | LONG-RANGE INTERACTION | DNA-BINDING | SUPER-ENHANCERS | GENE CBFB-MYH11 | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | C-MYC | SELF-RENEWAL | CHROMOSOME CONFORMATION CAPTURE | ENHANCER ACTIVITY | CELL BIOLOGY | Chromatin - metabolism | Oncogene Proteins, Fusion - metabolism | Transcription Factors - chemistry | Apoptosis - drug effects | Polycomb Repressive Complex 1 - metabolism | Humans | Chromosome Inversion - drug effects | Core Binding Factor Alpha 2 Subunit - chemistry | Leukemia, Myeloid, Acute - drug therapy | Benzimidazoles - therapeutic use | Disease Models, Animal | Triazoles - therapeutic use | Promoter Regions, Genetic | Chromosomal Proteins, Non-Histone - metabolism | Core Binding Factor Alpha 2 Subunit - metabolism | Leukemia, Myeloid, Acute - pathology | Mice, Inbred C57BL | Kaplan-Meier Estimate | Nuclear Proteins - metabolism | DNA - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Azepines - therapeutic use | Azepines - pharmacology | Leukemia, Myeloid, Acute - mortality | Transcription Factors - metabolism | Triazoles - pharmacology | DNA Helicases - metabolism | DNA - chemistry | Animals | Cell Line, Tumor | Protein Binding | Benzimidazoles - pharmacology | Oncogene Proteins, Fusion - antagonists & inhibitors | Mice | Proto-Oncogene Proteins c-myc - genetics | Chromosomal Proteins, Non-Histone - chemistry | Index Medicus
Journal Article