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Immunity, ISSN 1074-7613, 03/2014, Volume 40, Issue 3, pp. 355 - 366
Journal Article
Nature, ISSN 0028-0836, 06/2012, Volume 486, Issue 7403, pp. 405 - 409
Journal Article
Molecular Cell, ISSN 1097-2765, 02/2012, Volume 45, Issue 3, pp. 330 - 343
Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs to specific loci in mammalian... 
TRANSFORMATION | MAINTENANCE | ADULT HEMATOPOIESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEMATOPOIETIC STEM-CELLS | CBFA2 | MEGAKARYOCYTE | MICE | DIFFERENTIATION | RUNX1 | HAPLOINSUFFICIENCY | CELL BIOLOGY | Chromatin - metabolism | Thymocytes - metabolism | Protein Multimerization | Gene Expression Profiling | Core Binding Factor beta Subunit - genetics | Zebrafish - embryology | Gene Knockdown Techniques | T-Lymphocytes - metabolism | Hematopoietic Stem Cells - physiology | Repressor Proteins - isolation & purification | Megakaryocytes - metabolism | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Core Binding Factor beta Subunit - metabolism | Proto-Oncogene Proteins - metabolism | Cell Line | Core Binding Factor Alpha 2 Subunit - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Ubiquitin-Protein Ligases - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Polycomb-Group Proteins | Zebrafish - genetics | Mice, Knockout | Animals | Chromatography, Affinity | Polycomb Repressive Complex 1 | Protein Binding | Mice | Ubiquitin-Protein Ligases - genetics | Core Binding Factor Alpha 2 Subunit - genetics | Cluster Analysis | Computer science | Employee recruitment | Chromatin | Genomics | Genes | Stem cells | Chemical properties | DNA binding proteins | Artificial intelligence | Genetic research | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 05/2016, Volume 127, Issue 20, pp. 2451 - 2459
Journal Article
Blood, ISSN 0006-4971, 05/2014, Volume 123, Issue 19, pp. 2968 - 2977
Runx1 and Cbf beta are critical for the establishment of definitive hematopoiesis and are implicated in leukemic transformation. Despite the absolute... 
LINEAGE COMMITMENT | STEM-CELLS | HUMAN BONE-MARROW | IN-VIVO | ACUTE MYELOID-LEUKEMIA | HEMATOLOGY | TRANSCRIPTION FACTOR | COMMITTED PROGENITORS | EXPRESSION | FETAL LIVER HEMATOPOIESIS | BINDING-FACTOR | Core Binding Factor Alpha 3 Subunit - metabolism | Interferon Regulatory Factors - metabolism | Anemia - pathology | Myeloproliferative Disorders - pathology | Core Binding Factor beta Subunit - genetics | Stem Cells - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Myeloproliferative Disorders - genetics | Cell Differentiation - genetics | Anemia - genetics | Flow Cytometry | Myeloproliferative Disorders - metabolism | Granulocytes - metabolism | Dendritic Cells - metabolism | Core Binding Factor beta Subunit - metabolism | Gene Expression | Core Binding Factor Alpha 2 Subunit - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interferon Regulatory Factors - genetics | Hematopoiesis - genetics | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | fms-Like Tyrosine Kinase 3 - metabolism | Mice, Knockout | Anemia - metabolism | Animals | Core Binding Factor Alpha 3 Subunit - genetics | Mice | Core Binding Factor Alpha 2 Subunit - genetics | Bone Marrow Cells - metabolism | Core Binding Factor Alpha 1 Subunit - genetics | Index Medicus | Abridged Index Medicus | Hematopoiesis and Stem Cells
Journal Article
Leukemia, ISSN 0887-6924, 2012, Volume 26, Issue 8, pp. 1829 - 1841
The t(8;21) translocation fuses the DNA-binding domain of the hematopoietic master regulator RUNX1 to the ETO protein. The resultant RUNX1/ETO fusion protein... 
acute myeloid leukemia | chromatin | epigenetic regulation | integrated analysis of high-throughput data | RUNX1/ETO | AML1-ETO | STEM-CELLS | ACUTE MYELOGENOUS LEUKEMIA | SELF-RENEWAL | ACUTE MYELOID-LEUKEMIA | HEMATOPOIESIS | ONCOLOGY | IN-VIVO | FUSION PROTEIN | GENE-EXPRESSION | DIFFERENTIATION | HEMATOLOGY | Chromatin - metabolism | Translocation, Genetic | Oncogene Proteins, Fusion - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Transcriptional Activation | CCAAT-Binding Factor - genetics | Gene Expression Profiling | RNA Polymerase II - metabolism | Cell Differentiation - genetics | CCAAT-Binding Factor - metabolism | Acetylation | Binding Sites | Chromosomes, Human, Pair 21 | Proto-Oncogene Proteins - metabolism | Core Binding Factor Alpha 2 Subunit - metabolism | Gene Silencing | Proto-Oncogene Proteins - genetics | Chromosomes, Human, Pair 8 | Transcription Factors - genetics | RUNX1 Translocation Partner 1 Protein | Transcription Factors - metabolism | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Protein Binding | Histones - metabolism | Mutation | Chromatin - genetics | Core Binding Factor Alpha 2 Subunit - genetics | Cluster Analysis | Leukemia, Myeloid, Acute - genetics | Physiological aspects | Chromatin | Transcription factors | Research | Gene expression | Cell lines | Index Medicus | ETO | Original | RUNX1
Journal Article
Journal Article