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Immunity (Cambridge, Mass.), ISSN 1074-7613, 2014, Volume 40, Issue 3, pp. 355 - 366
Journal Article
Blood, ISSN 0006-4971, 05/2014, Volume 123, Issue 19, pp. 2968 - 2977
.... Despite the absolute requirements for these factors in the development of hematopoietic stem cells and lymphocytes, their roles in the development of bone marrow progenitor subsets have not been... 
LINEAGE COMMITMENT | STEM-CELLS | HUMAN BONE-MARROW | IN-VIVO | ACUTE MYELOID-LEUKEMIA | HEMATOLOGY | TRANSCRIPTION FACTOR | COMMITTED PROGENITORS | EXPRESSION | FETAL LIVER HEMATOPOIESIS | BINDING-FACTOR | Core Binding Factor Alpha 3 Subunit - metabolism | Interferon Regulatory Factors - metabolism | Anemia - pathology | Myeloproliferative Disorders - pathology | Core Binding Factor beta Subunit - genetics | Stem Cells - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Myeloproliferative Disorders - genetics | Cell Differentiation - genetics | Anemia - genetics | Flow Cytometry | Myeloproliferative Disorders - metabolism | Granulocytes - metabolism | Dendritic Cells - metabolism | Core Binding Factor beta Subunit - metabolism | Gene Expression | Core Binding Factor Alpha 2 Subunit - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interferon Regulatory Factors - genetics | Hematopoiesis - genetics | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | fms-Like Tyrosine Kinase 3 - metabolism | Mice, Knockout | Anemia - metabolism | Animals | Core Binding Factor Alpha 3 Subunit - genetics | Mice | Core Binding Factor Alpha 2 Subunit - genetics | Bone Marrow Cells - metabolism | Core Binding Factor Alpha 1 Subunit - genetics | Hematopoiesis and Stem Cells
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 07/2016, Volume 30, Issue 7, pp. 733 - 747
Journal Article
Molecular cell, ISSN 1097-2765, 2012, Volume 45, Issue 3, pp. 330 - 343
... transcription factor complex. Genome-wide studies in megakaryocytic cells demonstrate significant chromatin occupancy overlap between the PRC1 core component Ring1b and Runx1/CBFβ... 
TRANSFORMATION | MAINTENANCE | ADULT HEMATOPOIESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEMATOPOIETIC STEM-CELLS | CBFA2 | MEGAKARYOCYTE | MICE | DIFFERENTIATION | RUNX1 | HAPLOINSUFFICIENCY | CELL BIOLOGY | Chromatin - metabolism | Thymocytes - metabolism | Protein Multimerization | Gene Expression Profiling | Core Binding Factor beta Subunit - genetics | Zebrafish - embryology | Gene Knockdown Techniques | T-Lymphocytes - metabolism | Hematopoietic Stem Cells - physiology | Repressor Proteins - isolation & purification | Megakaryocytes - metabolism | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Core Binding Factor beta Subunit - metabolism | Proto-Oncogene Proteins - metabolism | Cell Line | Core Binding Factor Alpha 2 Subunit - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Ubiquitin-Protein Ligases - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Polycomb-Group Proteins | Zebrafish - genetics | Mice, Knockout | Animals | Chromatography, Affinity | Polycomb Repressive Complex 1 | Protein Binding | Mice | Ubiquitin-Protein Ligases - genetics | Core Binding Factor Alpha 2 Subunit - genetics | Cluster Analysis | Computer science | Employee recruitment | Chromatin | Genomics | Genes | Stem cells | Chemical properties | DNA binding proteins | Artificial intelligence | Genetic research
Journal Article
Cell Cycle, ISSN 1538-4101, 05/2012, Volume 11, Issue 10, pp. 1938 - 1947
Journal Article
Nature immunology, ISSN 1529-2916, 2015, Volume 16, Issue 11, pp. 1124 - 1133
.... Here we report that the transcription factor Runx3 was essential for the normal development of ILC1 and ILC3 cells but not of ILC2 cells... 
IMMUNITY | ROR-GAMMA-T | ARYL-HYDROCARBON RECEPTOR | TRANSCRIPTION FACTOR GATA3 | IFN-GAMMA | DRIVES | NOTCH | NKP46(+) CELLS | DIFFERENTIATION | IMMUNOLOGY | TISSUE INDUCER CELLS | Core Binding Factor Alpha 3 Subunit - metabolism | Core Binding Factor beta Subunit - deficiency | Citrobacter rodentium - pathogenicity | Core Binding Factor beta Subunit - genetics | Lymphocyte Subsets - immunology | Enterobacteriaceae Infections - immunology | Intestinal Mucosa - cytology | Lymphocyte Subsets - metabolism | Lymphocyte Subsets - cytology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Intestinal Mucosa - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Receptors, Aryl Hydrocarbon - metabolism | Antigens, Ly - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - deficiency | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Core Binding Factor beta Subunit - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Citrobacter rodentium - immunology | Mice, Inbred C57BL | Receptors, Aryl Hydrocarbon - genetics | Enterobacteriaceae Infections - etiology | Immunity, Innate | Mice, Knockout | Cell Differentiation - immunology | Animals | Core Binding Factor Alpha 3 Subunit - deficiency | Interleukin-7 Receptor alpha Subunit - metabolism | Core Binding Factor Alpha 3 Subunit - genetics | Natural Cytotoxicity Triggering Receptor 1 - metabolism | Mice | Cell Lineage - immunology | Physiological aspects | Genetic aspects | Immune response | Research | B cells
Journal Article
Leukemia, ISSN 0887-6924, 2012, Volume 26, Issue 8, pp. 1829 - 1841
Journal Article
Molecular cell, ISSN 1097-2765, 2013, Volume 49, Issue 4, pp. 632 - 644
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2008, Volume 319, Issue 5864, pp. 822 - 825
...⁻ helper-like T cells upon loss of Runx transcription factor complexes. A Runx-binding sequence within the Th-POK locus acts as a transcriptional silencer that is essential for Th-POK repression and for development of CD8⁺ T cells... 
T lymphocytes | Silencers | Transcription factors | Thymocytes | Developmental biology | Transgenic animals | Genetic loci | Reports | Repression | Cellular differentiation | T cell antigen receptors | LINEAGE DIFFERENTIATION | CD4 | COMMITMENT | POSITIVE SELECTION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | SILENCER | PROTEINS | FATE | DURATION | T-Lymphocyte Subsets - immunology | Silencer Elements, Transcriptional | T-Lymphocyte Subsets - cytology | Molecular Sequence Data | Core Binding Factor Alpha 2 Subunit - physiology | Chromatin Immunoprecipitation | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - cytology | Cell Differentiation | Core Binding Factor beta Subunit - metabolism | T-Lymphocytes, Cytotoxic - immunology | Transcription Factors - physiology | T-Lymphocytes, Helper-Inducer - metabolism | Histocompatibility Antigens Class I - immunology | Mice, Transgenic | Transcription Factors - genetics | Core Binding Factor Alpha 3 Subunit - physiology | Cell Lineage | Animals | Histocompatibility Antigens Class II - immunology | T-Lymphocytes, Cytotoxic - metabolism | T-Lymphocyte Subsets - metabolism | Core Binding Factor Alpha 3 Subunit - genetics | Mice | Core Binding Factor Alpha 2 Subunit - genetics | T-Lymphocytes, Cytotoxic - cytology | Genetic aspects | DNA binding proteins | Research | Properties | T cells | Gene expression | Genetics | Biomedical research | Immunology | Cellular biology | Rodents | Binding sites
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2011, Volume 286, Issue 14, pp. 11960 - 11969
...) of an SP1-like motif in Canscript. The unknown transcription factor binding to the SP1-like motif may hold the key for the cancer... 
TRANSCRIPTION FACTORS | IMMUNOTOXIN SS1P | SERIAL ANALYSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PANCREATIC CANCERS | CARCINOMAS | OVARIAN | TISSUE MICROARRAY | PROTEINS | PHASE-I | EXPRESSION | Core Binding Factor Alpha 3 Subunit - metabolism | Kruppel-Like Factor 6 | Humans | Sp1 Transcription Factor - metabolism | Neoplasm Proteins - metabolism | Phosphoproteins - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Promoter Regions, Genetic - genetics | Nucleic Acid Amplification Techniques | DNA-Binding Proteins - metabolism | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Chromatin Immunoprecipitation | Neoplasms - genetics | Kruppel-Like Transcription Factors - metabolism | HEK293 Cells | Electrophoretic Mobility Shift Assay | Membrane Proteins - metabolism | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins - metabolism | Cell Line | Mucin-1 - metabolism | Core Binding Factor Alpha 2 Subunit - metabolism | Membrane Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Blotting, Western | GPI-Linked Proteins - metabolism | Transcription Factors - metabolism | Tissue Inhibitor of Metalloproteinase-1 - genetics | Cell Cycle | Sp1 Transcription Factor - genetics | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Core Binding Factor Alpha 3 Subunit - genetics | RNA, Small Interfering | Zinc Finger Protein GLI1 | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | Core Binding Factor Alpha 2 Subunit - genetics | Kruppel-Like Transcription Factors - genetics | Core Binding Factor Alpha 1 Subunit - genetics | Apoptosis | GPI-Linked Proteins - genetics | Mucin-1 - genetics | Gene Regulation | YAP1 | Transcription Regulation | KLF6 | Canscript | Mesothelin | Gene Structure | Tumor Promoter | Tumor Marker
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2013, Volume 210, Issue 1, pp. 71 - 84
Previous studies have identified Notch as a key regulator of hematopoietic stem cell (HSC) development, but the underlying downstream mechanisms remain... 
MEDICINE, RESEARCH & EXPERIMENTAL | DEFINITIVE HEMATOPOIESIS | TRANSCRIPTION FACTOR GATA-2 | GENE | PATHWAY | MOUSE | LIGAND JAGGED1 | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | LINEAGE | MICE LACKING | Mesonephros - growth & development | Transcription Factor HES-1 | Embryo, Mammalian | Receptors, Notch - metabolism | Homeodomain Proteins - metabolism | Proto-Oncogene Proteins c-myb - genetics | Receptors, Notch - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Hematopoietic Stem Cells - physiology | Female | Binding Sites | Immunoglobulin J Recombination Signal Sequence-Binding Protein - genetics | GATA2 Transcription Factor - genetics | Repressor Proteins - metabolism | Endothelium, Vascular - embryology | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Promoter Regions, Genetic | Basic Helix-Loop-Helix Transcription Factors - genetics | Core Binding Factor Alpha 2 Subunit - metabolism | Signal Transduction | Mesonephros - cytology | Mice, Inbred C57BL | Aorta - embryology | Repressor Proteins - genetics | Mice, Transgenic | Homeodomain Proteins - genetics | Proto-Oncogene Proteins c-myb - metabolism | Animals | Hematopoietic Stem Cells - cytology | GATA2 Transcription Factor - metabolism | Mice | Aorta - cytology | Core Binding Factor Alpha 2 Subunit - genetics | 308
Journal Article