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International Journal of Pharmaceutics, ISSN 0378-5173, 2011, Volume 411, Issue 1, pp. 69 - 77
Conventional eye drops can result in poor drug bioavailability due to the unique ocular anatomy and physiology. Ion-activated gelling systems are able to... 
In vitro release | Anionic polysaccharides | Contact angle | Ocular drug delivery | Gelling behaviour | In situ gelling systems | XANTHAN GUM | GELS | DOSAGE FORM | OPHTHALMIC DELIVERY | RHEOLOGICAL CHARACTERIZATION | IOTA-CARRAGEENAN | PEFLOXACIN MESYLATE | PHARMACOLOGY & PHARMACY | SUSTAINED-RELEASE | EYE DROPS | DEACETYLATED GELLAN GUM | Viscosity | Administration, Ophthalmic | Gels - analysis | Humans | Carrageenan - chemistry | Ophthalmic Solutions - chemistry | Biological Availability | Excipients - analysis | Eye | Hexuronic Acids - analysis | Excipients - chemistry | Chemical Phenomena | Polysaccharides - chemistry | Gels - chemistry | Glucuronic Acid - chemistry | Glucuronic Acid - analysis | Polysaccharides, Bacterial - chemistry | Ophthalmic Solutions - administration & dosage | Rheology | Tears - chemistry | Cornea - chemistry | Solubility | Hexuronic Acids - chemistry | Polysaccharides - analysis | Alginates - analysis | Chitosan - analysis | Chitosan - chemistry | Alginates - chemistry | Polymers - chemistry | Drug Delivery Systems - methods | Carrageenan - analysis | Polysaccharides, Bacterial - analysis | Drugs | Methylcellulose | Drug delivery systems | Polysaccharides | Surface active agents | Pilocarpine | Universities and colleges | Comparative analysis | Calcium chloride | Vehicles | chitosan | Cornea | carrageenans | Alginic acid | Xanthan gum | Drug delivery | Bioavailability | Drainage | Cations | gellan gum | Mechanical stimuli | Tears | Irritation
Journal Article
Phytochemistry, ISSN 0031-9422, 2009, Volume 70, Issue 7, pp. 907 - 912
A xanthone, 1,5-dihydroxy-3,6-dimethoxy-2,7-diprenylxanthone was isolated from (Clusiaceae) and a triterpene, 3β-hydroxy-5-glutinen-28-oic acid from , along... 
Isoxanthochymol | Plasmodium falciparum | Garcinia cornea | 3β-Hydroxy-5-glutinen-28-oic acid | Garcinia celebica | Garcinia griffithii | Clusiaceae | Garcihombronane D | Garcinia cymosa | 1,5-Dihydroxy-3,6-dimethoxy-2,7-diprenylxanthone | Antiprotozoal activity | LANOSTANES | 3 beta-Hydroxy-5-glutinen-28-oic acid | 2D NMR | NATURAL-PRODUCTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | XANTHONES | LEADING COMPOUNDS | PLANT SCIENCES | FRIEDOLANOSTANES | ROOT BARK | BENZOPHENONES | VIRUS HIV INFECTION | ASSIGNMENTS | Triterpenes - pharmacology | Sitosterols - pharmacology | Benzophenones - pharmacology | Stigmasterol - pharmacology | Lanosterol - pharmacology | Lanosterol - analogs & derivatives | Stigmasterol - chemistry | Flavones - chemistry | Plasmodium falciparum - drug effects | Xanthones - pharmacology | Plant Bark - chemistry | Antimalarials - isolation & purification | Triterpenes - chemistry | Garcinia - chemistry | Glucosides - chemistry | Sitosterols - chemistry | Molecular Structure | Flavones - isolation & purification | Catechin - pharmacology | Stigmasterol - analogs & derivatives | Stigmasterol - isolation & purification | Benzophenones - isolation & purification | Plant Leaves - chemistry | Xanthones - chemistry | Benzophenones - chemistry | Glucosides - pharmacology | Plants, Medicinal - chemistry | Xanthones - isolation & purification | Sitosterols - isolation & purification | Antiprotozoal Agents - chemistry | Lanosterol - isolation & purification | Antiprotozoal Agents - pharmacology | Antimalarials - pharmacology | Antiprotozoal Agents - isolation & purification | Glucosides - isolation & purification | Animals | Lanosterol - chemistry | Antimalarials - chemistry | Catechin - isolation & purification | Triterpenes - isolation & purification | Catechin - chemistry | Indonesia | Saponins | Malaria | Analysis | Pharmacy | Universities and colleges | Terpenes | Isoflavones
Journal Article
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 10/2015, Volume 96, pp. 442 - 446
Mucus layer covers the ocular surface, and soluble mucins are also present in the tear fluid. After topical ocular drug administration, the drugs and... 
Conjunctival permeation | Mucin | Nanoparticle | Mucus | Mucoadhesion | Ocular drug delivery | Corneal permeation | MUCOADHESIVE POLYMERS | BETA-BLOCKING-AGENTS | SYSTEMIC ABSORPTION | PILOCARPINE | PERMEABILITY | CELL-SURFACE | TEAR FILM | CORNEAL PENETRATION BEHAVIOR | SURFACE MUCINS | PHARMACOLOGY & PHARMACY | DIFFUSION | Administration, Ophthalmic | Blood-Retinal Barrier - secretion | Lacrimal Apparatus - chemistry | Nanoparticles - chemistry | Absorption, Physiological | Humans | Drug Carriers - administration & dosage | Mucous Membrane - secretion | Conjunctiva - metabolism | Cornea - secretion | Tissue Distribution | Blood-Retinal Barrier - chemistry | Blood-Aqueous Barrier - secretion | Lacrimal Apparatus - secretion | Conjunctiva - chemistry | Mucins - metabolism | Mucus - metabolism | Glycocalyx - chemistry | Eye - metabolism | Eye - chemistry | Cornea - chemistry | Mucus - secretion | Mucins - chemistry | Permeability | Conjunctiva - secretion | Lacrimal Apparatus - metabolism | Mucins - secretion | Blood-Aqueous Barrier - metabolism | Mucous Membrane - metabolism | Blood-Retinal Barrier - metabolism | Cornea - metabolism | Animals | Mucous Membrane - chemistry | Drug Carriers - pharmacokinetics | Mucus - chemistry | Glycocalyx - secretion | Blood-Aqueous Barrier - chemistry | Pharmacokinetics | Eye - secretion | Glycocalyx - metabolism | Drugs | Drug delivery systems | Ophthalmic drugs | Vehicles
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 01/2017, Volume 110, pp. 58 - 69
Journal Article
AAPS PharmSciTech, ISSN 1530-9932, 12/2011, Volume 12, Issue 4, pp. 1335 - 1347
The bioavailability of therapeutic agents from eye drops is usually limited due to corneal barrier functions and effective eye protective mechanisms.... 
Biochemistry, general | Biotechnology | Biomedicine | brimonidine | intraocular pressure | sustained release | Pharmacy | physicochemical characterization | Pharmacology/Toxicology | ocular insert | CONTROLLED-RELEASE | INCLUSION COMPLEXES | POLYMERIC FILMS | SODIUM ALGINATE | BLEND FILMS | SOLID DISPERSIONS | FORMULATIONS | PHARMACOLOGY & PHARMACY | OPHTHALMIC DRUG-DELIVERY | TOPICAL DELIVERY | Administration, Ophthalmic | Intraocular Pressure - drug effects | Adrenergic alpha-2 Receptor Agonists - chemistry | Methylcellulose - analogs & derivatives | Spectroscopy, Fourier Transform Infrared | Drug Carriers | Adrenergic alpha-2 Receptor Agonists - administration & dosage | Cellulose - chemistry | X-Ray Diffraction | Drug Compounding | Ophthalmic Solutions | Acrylic Resins | Glucuronic Acid - chemistry | Glaucoma - physiopathology | Cellulose - analogs & derivatives | Disease Models, Animal | Rabbits | Quinoxalines - administration & dosage | Solubility | Quinoxalines - chemistry | Glaucoma - drug therapy | Technology, Pharmaceutical - methods | Brimonidine Tartrate | Hexuronic Acids - chemistry | Polymethacrylic Acids - chemistry | Chemistry, Pharmaceutical | Absorbable Implants | Methylcellulose - chemistry | Povidone - chemistry | Animals | Chitosan - chemistry | Hypromellose Derivatives | Alginates - chemistry | Hydrophobic and Hydrophilic Interactions | Calorimetry, Differential Scanning | Polymers - chemistry | Kinetics | Delayed-Action Preparations | Polyvinyls - chemistry | Brimonidine | Universities and colleges | Polymers | Sulfonamides | Drugstores | Drugs | Viscosity | Solvents | chitosan | Cornea | Biodegradability | polyvinylpyrrolidone | sodium alginate | Drug delivery | Bioavailability | Hydrophobicity | Coatings | Pressure | Eye
Journal Article
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 08/2015, Volume 492, Issue 1-2, pp. 28 - 39
Polymeric micelles that can deliver drug to intended sites of the eye have attracted much scientific attention recently. The aim of this study was to evaluate... 
Ocular drug delivery | Lornoxicam | Single and mixed nanomicellar systems | Confocal laser scanning microscopy | Histopathological studies | AQUEOUS-SOLUTIONS | DRUG-DELIVERY | COPOLYMERS | RELEASE | MIXED MICELLES | FORMULATION | MICELLAR SOLUBILIZATION | NANOSTRUCTURED LIPID CARRIERS | ETHYLENE-OXIDE | PHARMACOLOGY & PHARMACY | OPTIMIZATION | Administration, Ophthalmic | Fluorescent Dyes - pharmacokinetics | Rhodamines - administration & dosage | Piroxicam - toxicity | Piroxicam - administration & dosage | Drug Carriers - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Drug Carriers - toxicity | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Cornea - drug effects | Cornea - pathology | Piroxicam - analogs & derivatives | Rhodamines - chemistry | Fluorescent Dyes - administration & dosage | Polyethylenes - chemistry | Fluorescent Dyes - chemistry | Rabbits | Ethylenediamines - chemistry | Solubility | Rhodamines - pharmacokinetics | Anti-Inflammatory Agents, Non-Steroidal - toxicity | Particle Size | Cornea - metabolism | Animals | Piroxicam - chemistry | Nanostructures - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Drug Liberation | Nanostructures - chemistry | Polypropylenes - chemistry | Drug Carriers - pharmacokinetics | Nanostructures - toxicity | Pharmacy
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 12/2013, Volume 458, Issue 2, pp. 305 - 314
Journal Article
Carbohydrate Polymers, ISSN 0144-8617, 04/2013, Volume 94, Issue 1, pp. 286 - 291
► Preparation of tamarind seed xyloglucan nanoaggregates. ► Optimization of tropicamide-loaded TSX nanoaggregates using face centred design. ► Corneal... 
Tropicamide | Vero cell | HET-CAM | Xylogulcan | Nanoaggregates | POLYMER SCIENCE | DRUG-DELIVERY | BEHAVIOR | CHEMISTRY, ORGANIC | PROLIFERATION | MODEL | RABBIT | CHEMISTRY, APPLIED