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1. Full Text Antimicrobial Efficacy of Riboflavin/UVA Combination (365 nm) In Vitro for Bacterial and Fungal Isolates: A Potential New Treatment for Infectious Keratitis
by Martins, Suy Anne R and Combs, Juan Castro and Noguera, Guillermo and Camacho, Walter and Wittmann, Priscila and Walther, Rhonda and Cano, Marisol and Dick, James and Behrens, Ashley
Investigative ophthalmology & visual science, ISSN 0146-0404, 08/2008, Volume 49, Issue 8, pp. 3402 - 3408
Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Eye and associated structures. Visual pathways and centers. Vision | Diseases of cornea, anterior segment and sclera | Biological and medical sciences | Medical sciences | Staphylococcus aureus - radiation effects | Staphylococcus epidermidis - drug effects | Drug Resistance, Multiple | Bacteria - drug effects | Drug Resistance, Bacterial | Colony Count, Microbial | Flavin Mononucleotide - pharmacology | Photosensitizing Agents - pharmacology | Candida albicans - drug effects | Ultraviolet Rays | Corneal Ulcer - radiotherapy | Corneal Ulcer - microbiology | Fungi - radiation effects | Staphylococcus epidermidis - radiation effects | Streptococcus pneumoniae - drug effects | Fungi - drug effects | Ultraviolet Therapy | Pseudomonas aeruginosa - radiation effects | Combined Modality Therapy | Pseudomonas aeruginosa - drug effects | Candida albicans - radiation effects | Corneal Ulcer - drug therapy | Bacteria - radiation effects | Staphylococcus aureus - drug effects | Streptococcus pneumoniae - radiation effects | Index Medicus
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2. Full Text Substance P promotes diabetic corneal epithelial wound healing through molecular mechanisms mediated via the neurokinin-1 receptor
by Yang, Lingling and Di, Guohu and Qi, Xia and Qu, Mingli and Wang, Yao and Duan, Haoyun and Danielson, Patrik and Xie, Lixin and Zhou, Qingjun
Diabetes (New York, N.Y.), ISSN 0012-1797, 12/2014, Volume 63, Issue 12, pp. 4262 - 4274
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Sirtuin 1 - metabolism | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Epithelial Cells - drug effects | Receptor, Epidermal Growth Factor - drug effects | Male | Substance P - pharmacology | Corneal Injuries - metabolism | Receptor, Epidermal Growth Factor - metabolism | Cornea - drug effects | Diabetes Mellitus, Experimental | Neurotransmitter Agents - pharmacology | Diabetes Mellitus, Type 1 | Receptors, Neurokinin-1 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Wound Healing - drug effects | Cell Line | Mice, Inbred C57BL | Touch - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Hyperglycemia - metabolism | Cornea - metabolism | Receptors, Neurokinin-1 - drug effects | Animals | Sirtuin 1 - drug effects | Mice | Wound Healing - physiology | Touch - physiology | Proto-Oncogene Proteins c-akt - drug effects | Complications and side effects | Corneal diseases | Wound healing | Diabetes | Health aspects | Risk factors | Hyperglycemia | Rodents | Homeostasis | Glucose | Cells | Index Medicus | Abridged Index Medicus
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3. Full Text Safety of UVA-Riboflavin Cross-Linking of the Cornea
by Spoerl, Eberhard and Mrochen, Michael and Sliney, David and Trokel, Stephen and Seiler, Theo
Cornea, ISSN 0277-3740, 05/2007, Volume 26, Issue 4, pp. 385 - 389
UV | Cornea | Keratectasia | Cross-linking | Keratoconus | Collagen | Damage | Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Cornea - radiation effects | Corneal Stroma - drug effects | Cross-Linking Reagents | Riboflavin - adverse effects | Free Radicals | Humans | Radiation Tolerance | Photosensitizing Agents - adverse effects | Endothelium, Corneal - drug effects | Photochemotherapy | Ultraviolet Rays - adverse effects | Collagen - radiation effects | Animals | Cornea - drug effects | Endothelium, Corneal - radiation effects | Collagen - drug effects | Corneal Stroma - radiation effects | Fibroblasts - radiation effects | Fibroblasts - drug effects | Index Medicus
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4. Full Text Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks
by Sorkio, Anni and Koch, Lothar and Koivusalo, Laura and Deiwick, Andrea and Miettinen, Susanna and Chichkov, Boris and Skottman, Heli
Biomaterials, ISSN 0142-9612, 07/2018, Volume 171, pp. 57 - 71
Cornea | Adipose stem cells | Laser-assisted bioprinting | Human collagen I | Recombinant human laminin | 3D bioprinting | Human pluripotent stem cells | Limbal epithelial stem cells | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Bioprinting | Epithelial Cells - drug effects | Human Embryonic Stem Cells - cytology | Humans | Cornea - physiology | Ink | Adipose Tissue - cytology | Extracellular Matrix - metabolism | Corneal Stroma - cytology | Cornea - drug effects | Human Embryonic Stem Cells - drug effects | Lasers | Swine | Epithelial Cells - cytology | Organ Culture Techniques | Biomarkers - metabolism | Cell Survival - drug effects | Human Embryonic Stem Cells - metabolism | Tissue Engineering - methods | Cell Adhesion - drug effects | Animals | Cell Communication - drug effects | Cell Proliferation - drug effects | Collagen Type I - pharmacology | Limbus Corneae - cytology | Printing, Three-Dimensional | Usage | Laminin | Embryonic stem cells | Collagen | Index Medicus
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5. Full Text Nanostructured lipid carrier (NLC) coated with Chitosan Oligosaccharides and its potential use in ocular drug delivery system
by Luo, Qiuhua and Zhao, Junming and Zhang, Xiangrong and Pan, Weisan
International journal of pharmaceutics, ISSN 0378-5173, 01/2011, Volume 403, Issue 1-2, pp. 185 - 191
Controlled-release | Nanostructured lipid carrier | Corneal penetration | Ocular drug delivery | Gamma scintigraphy | Chitosan Oligosaccharides | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Pharmaceutical technology. Pharmaceutical industry | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Drug Carriers - adverse effects | Male | Drug Carriers - chemistry | Cornea - drug effects | Flurbiprofen - administration & dosage | Oligosaccharides - chemistry | Surface Properties | Drug Compounding | Nanostructures - adverse effects | Chitosan - adverse effects | Flurbiprofen - adverse effects | Microscopy, Electron, Transmission | Rabbits | Adhesiveness | Oligosaccharides - adverse effects | Permeability | Particle Size | Cornea - metabolism | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Chitosan - chemistry | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Nanostructures - chemistry | In Vitro Techniques | Administration, Topical | Ophthalmic drugs | Pharmacy | Transdermal medication | Index Medicus
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6. Full Text Targeting B-cell maturation antigen with GSK2857916 antibody–drug conjugate in relapsed or refractory multiple myeloma (BMA117159): a dose escalation and expansion phase 1 trial
by Trudel, Suzanne and Lendvai, Nikoletta and Popat, Rakesh and Voorhees, Peter M and Reeves, Brandi and Libby, Edward N and Richardson, Paul G and Anderson, Larry D and Sutherland, Heather J and Yong, Kwee and Hoos, Axel and Gorczyca, Michele M and Lahiri, Soumi and He, Zangdong and Austin, Daren J and Opalinska, Joanna B and Cohen, Adam D
The lancet oncology, ISSN 1470-2045, 12/2018, Volume 19, Issue 12, pp. 1641 - 1653
Life Sciences & Biomedicine | Oncology | Science & Technology | B-Cell Maturation Antigen - immunology | Antibodies, Monoclonal, Humanized - adverse effects | Antineoplastic Agents, Immunological - administration & dosage | Recurrence | United States | Humans | Middle Aged | Drug Resistance, Neoplasm | Male | Multiple Myeloma - immunology | Treatment Outcome | United Kingdom | Immunoconjugates - administration & dosage | B-Lymphocytes - drug effects | Canada | Antineoplastic Agents, Immunological - adverse effects | Multiple Myeloma - drug therapy | Antibodies, Monoclonal, Humanized - administration & dosage | B-Lymphocytes - immunology | Time Factors | Adult | Female | Aged | Immunoconjugates - adverse effects | Viral antibodies | Antigens | Relapse | Analysis | Multiple myeloma | Antibodies | Product development | Biopharmaceutics | Diseases | Index Medicus
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7. Full Text DynaMiTES – A dynamic cell culture platform for in vitro drug testing PART 2 – Ocular DynaMiTES for drug absorption studies of the anterior eye
by Beiβner, Nicole and Mattern, Kai and Dietzel, Andreas and Reichl, Stephan
European journal of pharmaceutics and biopharmaceutics, ISSN 0939-6411, 05/2018, Volume 126, pp. 166 - 176
DynaMiTES | Dynamic flow system | Organ on chip | Human hemicornea construct | Microfluidic system | Benzalkonium chloride | In vitro drug absorption | TEER measurement | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Cell Survival - drug effects | Drug Evaluation, Preclinical - methods | Tissue Engineering - methods | Humans | Middle Aged | Fluorescent Dyes - metabolism | Cell Culture Techniques - methods | Cornea - metabolism | Transendothelial and Transepithelial Migration - drug effects | Cornea - drug effects | Cell Membrane Permeability - physiology | Cell Membrane Permeability - drug effects | Equipment Design - methods | Female | Transendothelial and Transepithelial Migration - physiology | Fluorescent Dyes - administration & dosage | Cell Line, Transformed | Cell Survival - physiology | Index Medicus
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8. Full Text Fabrication and characterization of silk fibroin-coated liposomes for ocular drug delivery
by Dong, Yixuan and Dong, Pin and Huang, Di and Mei, Liling and Xia, Yaowen and Wang, Zhouhua and Pan, Xin and Li, Ge and Wu, Chuanbin
European journal of pharmaceutics and biopharmaceutics, ISSN 0939-6411, 04/2015, Volume 91, pp. 82 - 90
Cell culture | Sustained release | Silk fibroin | Liposomes | Coating | Ocular drug delivery | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Administration, Ophthalmic | Fibroins - chemistry | Pupa - chemistry | Bombyx - chemistry | Humans | Excipients - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Delayed-Action Preparations - chemistry | Delayed-Action Preparations - administration & dosage | Cornea - drug effects | Ibuprofen - chemistry | Ocular Absorption | Excipients - chemistry | Surface Properties | Drug Compounding | Cornea - cytology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Cell Survival - drug effects | Fibroins - isolation & purification | Protein Structure, Secondary | Adhesiveness | Cells, Cultured | Ibuprofen - administration & dosage | Fibroins - adverse effects | Ibuprofen - metabolism | Particle Size | Cornea - metabolism | Delayed-Action Preparations - metabolism | Excipients - isolation & purification | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Delayed-Action Preparations - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Drug Liberation | Ibuprofen - adverse effects | Drug Delivery Systems - adverse effects | Drugs | Silk | Drug delivery systems | Ophthalmic drugs | Vehicles | Index Medicus
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9. Full Text Nuclear p120 catenin unlocks mitotic block of contact-inhibited human corneal endothelial monolayers without disrupting adherent junctions
by Zhu, Ying-Ting and Chen, Hung-Chi and Chen, Szu-Yu and Tseng, Scheffer C. G
Journal of cell science, ISSN 0021-9533, 08/2012, Volume 125, Issue 15, pp. 3636 - 3648
Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Humans | Middle Aged | Fibroblast Growth Factor 2 - pharmacology | Cell Growth Processes - physiology | Epithelial-Mesenchymal Transition - drug effects | rhoA GTP-Binding Protein - metabolism | Wnt Proteins - metabolism | Contact Inhibition - drug effects | Young Adult | Catenins - metabolism | Cornea - drug effects | Transfection | rho-Associated Kinases - metabolism | Edetic Acid - pharmacology | Aged, 80 and over | Adult | Cornea - cytology | Transforming Growth Factor beta1 - pharmacology | Catenins - physiology | Endothelium, Corneal - cytology | Cell Growth Processes - drug effects | Cells, Cultured | Endothelium, Corneal - drug effects | Endothelium, Corneal - ultrastructure | Cell Adhesion - drug effects | Catenins - genetics | Contact Inhibition - physiology | Transcription Factors - metabolism | Mitosis - drug effects | Mitosis - physiology | Signal Transduction - drug effects | Adherens Junctions - physiology | Cell Adhesion - physiology | Adherens Junctions - drug effects | Adolescent | Aged | RNA, Small Interfering - administration & dosage | Index Medicus | Contact inhibition | Endothelial–mesenchymal transformation | Kaiso | p120 catenin | Proliferation | Human corneal endothelium
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10. Full Text Biomimetic hydrogels with pro-angiogenic properties
by Moon, James J and Saik, Jennifer E and Poché, Ross A and Leslie-Barbick, Julia E and Lee, Soo-Hong and Smith, April A and Dickinson, Mary E and West, Jennifer L
Biomaterials, ISSN 0142-9612, 2010, Volume 31, Issue 14, pp. 3840 - 3847
Advanced Basic Science | Dentistry | Smooth muscle cell | Endothelial cell | Hydrogel | Mesenchcymal stem cell | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Neovascularization, Physiologic - drug effects | Blood Vessels - growth & development | Coculture Techniques | Humans | Materials Testing | Microscopy, Video | Cell Lineage - drug effects | Biomimetic Materials - pharmacology | Animals | Cornea - blood supply | Cornea - drug effects | Time Factors | Cell Differentiation - drug effects | Endothelial Cells - cytology | Blood Vessels - drug effects | Mice | Hydrogels - pharmacology | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Umbilical Veins - cytology | Hydrogels - chemistry | Endothelial Cells - drug effects | Index Medicus
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