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Journal of Virology, ISSN 0022-538X, 2016, Volume 90, Issue 21, pp. 9683 - 9692
RNA viruses present an extraordinary threat to human health, given their sudden and unpredictable appearance, the potential for rapid spread among the human... 
DRUG | EFLORNITHINE | REPLICATION | VIROLOGY | ALPHA-DIFLUOROMETHYLORNITHINE | DEPLETION | INFECTION | TRANSLATION | MAMMALIAN-CELLS | RESPIRATORY SYNDROME CORONAVIRUS | SPERMIDINE | Zika Virus Infection - drug therapy | Acetyltransferases - metabolism | Ebolavirus - metabolism | Chikungunya virus - metabolism | Humans | Eflornithine - pharmacology | Ebolavirus - drug effects | Zika Virus Infection - virology | Disease Outbreaks | RNA Viruses - drug effects | Hemorrhagic Fever, Ebola - virology | Hemorrhagic Fever, Ebola - drug therapy | Spermine - analogs & derivatives | Cell Line | Virus Replication - drug effects | Antiviral Agents - pharmacology | Mice, Inbred C57BL | Chikungunya Fever - drug therapy | Zika Virus - drug effects | Chikungunya Fever - virology | Polyamines - metabolism | Chikungunya virus - drug effects | Animals | Spermine - pharmacology | Mice | Spermine/analogs & derivatives | Virus Replication/drug effects | Hemorrhagic Fever, Ebola/virology | Life Sciences | Zika Virus/drug effects | Immunology | Chikungunya virus/metabolism | Chikungunya Fever/drug therapy | Zika Virus Infection/drug therapy | Ebolavirus/drug effects | Acetyltransferases/metabolism | Chikungunya virus/drug effects | Eflornithine/pharmacology | Spermine/pharmacology | Polyamines/metabolism | Chikungunya Fever/virology | Hemorrhagic Fever, Ebola/drug therapy | Virology | Microbiology and Parasitology | Zika Virus Infection/virology | Ebolavirus/metabolism | Antiviral Agents/pharmacology | RNA Viruses/drug effects
Journal Article
Journal Article
Journal Article
Applied and Environmental Microbiology, ISSN 0099-2240, 09/2006, Volume 72, Issue 9, pp. 6111 - 6116
Journal Article
PLoS Pathogens, ISSN 1553-7366, 10/2012, Volume 8, Issue 10, p. e1002976
Viruses use a limited set of host pathways for infection. These pathways represent bona fide antiviral targets with low likelihood of viral resistance. We... 
RAT-LIVER | LOW-PH | CELLS | PLECONARIL | VIRUS | ENTRY | HUMAN RHINOVIRUSES | MICROBIOLOGY | NITAZOXANIDE | RESPIRATORY SYNDROME CORONAVIRUS | REPLICATION | VIROLOGY | PARASITOLOGY | Influenza viruses | Physiological aspects | Antiviral agents | Amides | Rhinoviruses | Health aspects | Proteins | Antibiotics | Microscopy | Viruses | Infections | Genomes | FDA approval | Drug dosages | Viral infections
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e41619
The lack of an animal model for human norovirus (HuNoV) has hindered the development of therapeutic strategies. This study demonstrated that a commonly used... 
UNITED-STATES | PATHOGENESIS | RESPONSES | SYNDROME VIRUS | MULTIDISCIPLINARY SCIENCES | DISEASE | GENE-EXPRESSION | HEPATITIS-C | GASTROENTERITIS | STATINS | PORCINE RESPIRATORY CORONAVIRUS | Intestines - drug effects | Interferon-alpha - pharmacology | Caliciviridae Infections - virology | Virus Shedding - drug effects | Enterocytes - metabolism | Cholesterol - blood | Humans | Sus scrofa - blood | NF-kappa B - metabolism | Simvastatin - pharmacology | Feces - virology | Macrophages - virology | Intestines - virology | Dendritic Cells - drug effects | Dendritic Cells - virology | Norovirus - drug effects | Caliciviridae Infections - immunology | Disease Models, Animal | Receptors, LDL - genetics | Virus Replication - drug effects | Antiviral Agents - pharmacology | Disease Susceptibility | Intestines - pathology | Norovirus - pathogenicity | Caliciviridae Infections - pathology | Receptors, LDL - metabolism | Germ-Free Life - drug effects | Sus scrofa - virology | Toll-Like Receptor 3 - metabolism | Gene Expression Regulation - drug effects | Interferon-alpha - administration & dosage | Phenotype | Animals | Enterocytes - drug effects | Interferon Regulatory Factor-3 - metabolism | Macrophages - drug effects | Viral Load - drug effects | Blood Group Antigens - metabolism | Drugs | Shedding | Veterinary colleges | Transcription factors | Viruses | Innate immunity | Infections | Macrophages | Veterinary medicine | Immunity | Proteins | Signal transduction | Swine | Infectivity | Toll-like receptors | Blood groups | Immunomodulators | Food | Immune system | Carbohydrates | Antigens | Medical research | Dendritic cells | Immunomodulation | Simvastatin | Poly (I:C) | Preventive medicine | Gene expression | Biological assays | Cholesterol | Studies | Disease prevention | Hogs | Signaling | Enterocytes | Interferon regulatory factor 3 | Interferon | Interferon regulatory factor | Viral infections
Journal Article
Scientific reports, ISSN 2045-2322, 2013, Volume 3, Issue 1, p. 1686
The identification of a novel β coronavirus, nCoV, as the causative agent of severe respiratory illness in humans originating in Saudi Arabia, Qatar and Jordan... 
Interferon-alpha - administration & dosage | Virus Replication - drug effects | Animals | Coronavirus - drug effects | Ribavirin - administration & dosage | Cercopithecus aethiops | Vero Cells | Virus Replication - physiology | Coronavirus - physiology | Drug Combinations
Journal Article
Journal Article