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Journal Article
Medicinal Chemistry, ISSN 1573-4064, 2015, Volume 11, Issue 1, pp. 50 - 59
Corticotropin-releasing factor (CRF) is a neurohormone that plays a crucial role in integrating the body's overall response to stress. It appears necessary and... 
Depression | Anxiety | Thiazolo[4,5-d]pyrimidines | Antalarmin | Corticotropin releasing factor | GEWALD REACTION | CHEMISTRY, MEDICINAL | POTENTIAL ANTI-MICROBIALS | RECEPTOR ANTAGONISTS | ALZHEIMERS-DISEASE | RATS | DISORDERS | PEPTIDE | anxiety | antalarmin | depression | corticotropin releasing factor | STRESS | Dopamine Plasma Membrane Transport Proteins - metabolism | Receptors, Corticotropin-Releasing Hormone - metabolism | Gene Expression - drug effects | Pyrimidines - chemical synthesis | Humans | Receptors, Corticotropin-Releasing Hormone - genetics | Neuropeptide Y - genetics | Structure-Activity Relationship | Monoamine Oxidase - genetics | Pyrimidines - chemistry | Neuropeptide Y - metabolism | Serotonin Plasma Membrane Transport Proteins - genetics | Anti-Anxiety Agents - chemical synthesis | Antidepressive Agents - chemistry | Dopamine beta-Hydroxylase - metabolism | HEK293 Cells | Anti-Anxiety Agents - chemistry | Antidepressive Agents - pharmacology | Corticotropin-Releasing Hormone - genetics | Binding Sites | Anti-Anxiety Agents - pharmacology | Pyrimidines - pharmacology | Dopamine Plasma Membrane Transport Proteins - genetics | Corticotropin-Releasing Hormone - metabolism | Serotonin Plasma Membrane Transport Proteins - metabolism | Cyclic AMP Response Element-Binding Protein - genetics | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Thiazoles - chemical synthesis | Dopamine beta-Hydroxylase - genetics | Cyclic AMP Response Element-Binding Protein - metabolism | Antidepressive Agents - chemical synthesis | Protein Binding | Thiazoles - chemistry | Thiazoles - pharmacology | Receptors, Corticotropin-Releasing Hormone - chemistry | Monoamine Oxidase - metabolism
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2001, Volume 98, Issue 13, pp. 7570 - 7575
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/1999, Volume 42, Issue 5, pp. 805 - 818
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 10/2017, Volume 18, Issue 10, p. 2201
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, pp. e0155762 - e0155762
Di-(2-ethylhexyl) phthalate (DEHP) has the potential to disrupt the thyroid endocrine system, but the underlying mechanism is unknown. In this study, zebrafish... 
DANIO-RERIO | HORMONE | TERM EXPOSURE | IODOTHYRONINE DEIODINASE | MULTIDISCIPLINARY SCIENCES | PHTHALIC-ACID ESTERS | FISH | ENDOCRINE DISRUPTION | MINNOW | PLASTICIZERS | REPRODUCTION | Hypothalamus - embryology | Thyroid Nuclear Factor 1 | Zebrafish Proteins - biosynthesis | Gene Expression Regulation, Developmental - drug effects | Thyroxine - blood | Corticotropin-Releasing Hormone - blood | Transcription Factors - biosynthesis | Zebrafish - embryology | PAX8 Transcription Factor - biosynthesis | Pituitary Gland - embryology | Triiodothyronine - blood | Animals | Nuclear Proteins - biosynthesis | Thyroglobulin - biosynthesis | Diethylhexyl Phthalate - toxicity | Thyroid Gland - embryology | Symporters - biosynthesis | Thyrotropin - blood | Physiological aspects | Hypothalamic-pituitary-adrenal axis | Genetic aspects | Research | Phthalates | Larvae | Profiling | Transcription | Toxicity | Genes | Homeostasis | Thyroid gland | Hormones | Hypothalamus | Receptors | Sodium/iodide symporter | Synthesis | Metabolites | Thyroxine | Down-regulation | Fish | Life sciences | Triiodothyronine | Thyroid hormones | Thyroid | Enzymes | Fertilization | Iodides | Thyroid hormone receptors | Endocrine system | Transthyretin | Iodide peroxidase | Zebrafish | Exposure | Metabolism | Mammals | Gene expression | Embryos | Studies | Sodium | Thyroglobulin | Hypothalamic-pituitary-thyroid axis | Pituitary | Thyroid transcription factor 1 | Pax8 protein | Index Medicus
Journal Article