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1. Full Text The sodium phosphate cotransporter family and nicotinamide phosphoribosyltransferase contribute to the daily oscillation of plasma inorganic phosphate concentration
by Miyagawa, Atsumi and Tatsumi, Sawako and Takahama, Wako and Fujii, Osamu and Nagamoto, Kenta and Kinoshita, Emi and Nomura, Kengo and Ikuta, Kayo and Fujii, Toru and Hanazaki, Ai and Kaneko, Ichiro and Segawa, Hiroko and Miyamoto, Ken-ichi
Kidney international, ISSN 0085-2538, 05/2018, Volume 93, Issue 5, pp. 1073 - 1085
NAD | phosphate | daily oscillation | Npt2c | Nampt | Npt2a | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Biomarkers - urine | Liver - enzymology | Sodium-Phosphate Cotransporter Proteins, Type IIb - genetics | Kidney - enzymology | Male | Mice, 129 Strain | Nicotinamide Phosphoribosyltransferase - antagonists & inhibitors | Sodium-Phosphate Cotransporter Proteins, Type IIb - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIa - metabolism | Nicotinamide Phosphoribosyltransferase - metabolism | Time Factors | Sodium-Phosphate Cotransporter Proteins, Type IIc - genetics | Sodium-Phosphate Cotransporter Proteins, Type IIc - metabolism | Phosphates - urine | Phosphates - blood | Female | Cytokines - genetics | NAD - metabolism | Cytokines - metabolism | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Biomarkers - blood | Nicotinamide Phosphoribosyltransferase - deficiency | Circadian Rhythm | Sodium-Phosphate Cotransporter Proteins, Type IIc - deficiency | Renal Elimination | Sodium-Phosphate Cotransporter Proteins, Type IIa - genetics | Nicotinamide Phosphoribosyltransferase - genetics | Animals | Sodium-Phosphate Cotransporter Proteins, Type IIb - deficiency | Sodium-Phosphate Cotransporter Proteins, Type IIa - deficiency | Cytokines - deficiency | Cytokines - antagonists & inhibitors | Intestines - enzymology | NADPH | Plasma | Renal function | Homeostasis | Proteins | Sodium phosphate | Clonal deletion | Intestine | Phosphate | Rodents | Light | Phosphoribosyltransferase | Intestinal absorption | Food | Excretion | Kidneys | Mortality | Reabsorption | Metabolism | Sodium | Hepatocytes | Food intake | Nicotinamide phosphoribosyltransferase | Nicotinamide | Kidney diseases | Index Medicus
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2. Full Text Proximal tubular handling of phosphate: A molecular perspective
by Forster, I.C and Hernando, N and Biber, J and Murer, H
Kidney international, ISSN 0085-2538, 11/2006, Volume 70, Issue 9, pp. 1548 - 1559
phosphate homeostasis | electrophysiology | proximal tubule | renal tubular epithelial cells | Electrophysiology | Proximal tubule | Renal tubular epithelial cells | Phosphate homeostasis | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Parathyroid Hormone - physiology | Sodium-Phosphate Cotransporter Proteins, Type IIb - genetics | Humans | Homeostasis | Structure-Activity Relationship | Sodium-Phosphate Cotransporter Proteins, Type IIb - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIa - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIc - chemistry | Sodium-Phosphate Cotransporter Proteins, Type IIa - genetics | Phosphates - metabolism | Animals | Sodium-Phosphate Cotransporter Proteins, Type IIb - chemistry | Sodium-Phosphate Cotransporter Proteins, Type IIc - genetics | Sodium-Phosphate Cotransporter Proteins, Type IIc - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIa - chemistry | Kidney Tubules, Proximal - metabolism | Mice | Index Medicus
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3. Full Text Renal phosphate handling and inherited disorders of phosphate reabsorption: an update
by Wagner, Carsten A and Wagner, Carsten A and Rubio-Aliaga, Isabel and Rubio-Aliaga, Isabel and Hernando, Nati and Hernando, Nati
Pediatric Nephrology, ISSN 0931-041X, 4/2019, Volume 34, Issue 4, pp. 549 - 559
SLC34A3 | Pediatrics | Proximal tubule | Nephrology | Nephrocalcinosis | Medicine & Public Health | Phosphate | SLC34A1 | Nephrolithiasis | FGF23 | Urology | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Prognosis | Humans | Renal Tubular Transport, Inborn Errors - genetics | Sodium-Phosphate Cotransporter Proteins, Type IIa - metabolism | Renal Reabsorption | Sodium-Phosphate Cotransporter Proteins, Type III - genetics | Renal Tubular Transport, Inborn Errors - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIc - genetics | Sodium-Phosphate Cotransporter Proteins, Type IIc - metabolism | Renal Tubular Transport, Inborn Errors - physiopathology | Sodium-Phosphate Cotransporter Proteins - metabolism | Genetic Predisposition to Disease | Risk Assessment | Risk Factors | Sodium-Phosphate Cotransporter Proteins - genetics | Heredity | Sodium-Phosphate Cotransporter Proteins, Type IIa - genetics | Phenotype | Phosphates - metabolism | Animals | Pedigree | Kidney Tubules, Proximal - metabolism | Sodium-Phosphate Cotransporter Proteins, Type III - metabolism | Mutation | Familial Hypophosphatemic Rickets | Kidneys | Carrier proteins | Development and progression | Phosphorus imbalance | Genetic aspects | Phosphorus metabolism | Health aspects | Vitamin D3 | Renal function | Homeostasis | Reabsorption | Genomes | Hereditary diseases | Hypercalcemia | Hypercalciuria | Rickets | Hypophosphatemia | Calcium homeostasis | Kidney transplantation | Kidney stones | Index Medicus
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4. Full Text Role of rat sodium/phosphate cotransporters in the cell membrane transport of arsenate
by Villa-Bellosta, Ricardo and Sorribas, Víctor
Toxicology and applied pharmacology, ISSN 0041-008X, 2008, Volume 232, Issue 1, pp. 125 - 134
Brush-border membrane vesicles | Arsenic | PiT-1 | Toxicokinetics | Phosphonoformate | Arsenate | Intestine | PiT-2 | NaPi-IIb | NaPi-IIa | NaPi-IIc | Xenopus laevis oocyte | Na/Pi cotransporter | Vascular smooth muscle cells | Phosphate transport | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Chemical agents | Carcinogenesis, carcinogens and anticarcinogens | Medical sciences | Chemical and industrial products toxicology. Toxic occupational diseases | Metals and various inorganic compounds | Tumors | Intestinal Mucosa - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIb - genetics | Arsenates - metabolism | Arsenates - toxicity | Sodium-Phosphate Cotransporter Proteins, Type IIb - antagonists & inhibitors | Sodium-Phosphate Cotransporter Proteins, Type IIb - metabolism | Oocytes | Sodium-Phosphate Cotransporter Proteins, Type IIa - metabolism | Dose-Response Relationship, Drug | Sodium-Phosphate Cotransporter Proteins, Type IIc - metabolism | Cloning, Molecular | Cell Membrane - metabolism | Sodium-Phosphate Cotransporter Proteins - metabolism | Myocytes, Smooth Muscle - metabolism | Sodium-Phosphate Cotransporter Proteins - genetics | Xenopus laevis | Cells, Cultured | Rats | Water Pollutants, Chemical - metabolism | Animals | Water Pollutants, Chemical - toxicity | Kidney Tubules, Proximal - metabolism | Sodium-Phosphate Cotransporter Proteins - antagonists & inhibitors | Sodium-Phosphate Cotransporter Proteins, Type III - metabolism | Intestine, Small - metabolism | Kinetics | Phosphates | Oxides | Cell membranes | Index Medicus | ARSENATES | FRESH WATER | RATS | INTESTINES | MEMBRANE TRANSPORT | 60 APPLIED LIFE SCIENCES | SODIUM PHOSPHATES | KIDNEYS | ARSENIC | SPECTROSCOPY | CELL MEMBRANES | URINE | OOCYTES | BILE | BLOOD
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5. Full Text The therapeutic potential of neuronal K‐Cl co‐ transporter KCC2 in Huntington’s disease and its comorbidities
by Andrews, Katie and Josiah, Sunday Solomon and Zhang, Jinwei
International journal of molecular sciences, ISSN 1661-6596, 12/2020, Volume 21, Issue 23, pp. 1 - 21
homeostasis | Sleep disorders | cotransporter 1 (NKCC1), K | cotransporter 2 (KCC2), Chloride (Cl | GABAergic | Huntington’s disease | 2Cl | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Brain | Phosphorylation | Disease | Cognitive ability | Homeostasis | Nervous system | Cognition | Kinases | Potassium-chloride cotransporter | Depolarization | γ-Aminobutyric acid | Chlorides | Physiology | Neurological disorders | Therapeutic applications | Abnormalities | Chloride transport | Excitability | Huntington's disease | Gene expression | Sleep | Protein interaction | Transporter | Apoptosis | Index Medicus | sleep disorders | Na+-K+-2Cl− cotransporter 1 (NKCC1), K+-2Cl− cotransporter 2 (KCC2), Chloride (Cl−) homeostasis
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6. Full Text Npt2a and Npt2c in mice play distinct and synergistic roles in inorganic phosphate metabolism and skeletal development
by Hiroko Segawa and Akemi Onitsuka and Junya Furutani and Ichiro Kaneko and Fumito Aranami and Natsuki Matsumoto and Yuka Tomoe and Masashi Kuwahata and Mikiko Ito and Mitsuru Matsumoto and Minqi Li and Norio Amizuka and Ken-ichi Miyamoto
American Journal of Physiology - Renal Physiology, ISSN 1931-857X, 09/2009, Volume 297, Issue 3, pp. 671 - 678
Hereditary hypophosphatemic rickets | Bone mineralization | Physiology | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Bone and Bones - pathology | Familial Hypophosphatemic Rickets - metabolism | Homeostasis | Hypercalciuria - pathology | Male | Sodium-Phosphate Cotransporter Proteins, Type IIa - metabolism | Familial Hypophosphatemic Rickets - genetics | Familial Hypophosphatemic Rickets - prevention & control | Sodium-Phosphate Cotransporter Proteins, Type IIc - genetics | Sodium-Phosphate Cotransporter Proteins, Type IIc - metabolism | Bone and Bones - metabolism | Phosphates - urine | Phosphorus, Dietary - administration & dosage | Aging | Familial Hypophosphatemic Rickets - pathology | Phosphates - blood | Female | Hypercalciuria - genetics | Kidney Tubules - metabolism | Calcification, Physiologic - genetics | Mice, Inbred C57BL | Genotype | Kidney Calculi - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIc - deficiency | Mice, Knockout | Sodium-Phosphate Cotransporter Proteins, Type IIa - genetics | Phenotype | Phosphates - metabolism | Animals | Microvilli - metabolism | Hypercalciuria - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIa - deficiency | Mice | Phosphates | Genotype & phenotype | Plasma | Genetic disorders | Rodents | Skeletal system | Metabolism | Index Medicus
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7. Full Text Voltage- and substrate-dependent interactions between sites in putative re-entrant domains of a Na+-coupled phosphate cotransporter
by Ghezzi, Chiara and Meinild, Anne-Kristine and Murer, Heini and Forster, Ian C
Pflügers Archiv, ISSN 0031-6768, 6/2011, Volume 461, Issue 6, pp. 645 - 663
Voltage dependence | Biomedicine | Human Physiology | Cross-linking | Membrane transport | Phosphate cotransport | Xenopus laevis | Electrophysiology | Fluorescence | Fluorometry | Na + cotransporter | cotransporter | Life Sciences & Biomedicine | Physiology | Science & Technology | Protein Structure, Tertiary | Amino Acid Sequence | Oocytes - metabolism | Sodium-Phosphate Cotransporter Proteins - genetics | Molecular Sequence Data | Flounder | Patch-Clamp Techniques | Animals | Sodium-Phosphate Cotransporter Proteins - chemistry | Cysteine - metabolism | Sodium-Phosphate Cotransporter Proteins - metabolism | Binding Sites | Amino Acid Substitution | Index Medicus
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8. Full Text Downregulation of NaPi-IIa and NaPi-IIb Na+-coupled Phosphate Transporters by Coexpression of Klotho
by Dërmaku-Sopjani, Miribane and Sopjani, Mentor and Saxena, Ambrish and Shojaiefard, Manzar and Bogatikov, Evgenii and Alesutan, Ioana and Eichenmüller, Melanie and Lang, Florian
Cellular physiology and biochemistry, ISSN 1015-8987, 08/2011, Volume 28, Issue 2, pp. 251 - 258
Original Paper | Life span | Intestine | Ageing | Kidney | Phosphate transport | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Intestines - drug effects | Intestinal Mucosa - metabolism | Kidney - drug effects | Oocytes - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIa - physiology | Sodium-Phosphate Cotransporter Proteins, Type IIb - genetics | Xenopus laevis | Glucuronidase - metabolism | Down-Regulation - drug effects | Sodium-Phosphate Cotransporter Proteins, Type IIb - metabolism | Calcifediol - pharmacology | Sodium-Phosphate Cotransporter Proteins, Type IIa - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIa - genetics | Kidney - metabolism | Phosphates - metabolism | Animals | Oocytes - physiology | Glucuronidase - genetics | Oocytes - drug effects | Mice | Sodium-Phosphate Cotransporter Proteins, Type IIb - physiology | Phosphates - pharmacology | Index Medicus
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