X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (6856) 6856
Publication (546) 546
Newsletter (80) 80
Book Review (27) 27
Book Chapter (26) 26
Conference Proceeding (15) 15
Book / eBook (5) 5
Dissertation (3) 3
Data Set (2) 2
Paper (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (3171) 3171
humans (2921) 2921
index medicus (2529) 2529
coumarins - pharmacology (2120) 2120
coumarins - metabolism (1748) 1748
male (1484) 1484
coumarins (1483) 1483
biochemistry & molecular biology (1459) 1459
coumarins - chemistry (1423) 1423
rats (1384) 1384
pharmacology & pharmacy (1351) 1351
mice (1063) 1063
coumarin (1014) 1014
chemistry, medicinal (889) 889
female (872) 872
kinetics (795) 795
structure-activity relationship (625) 625
metabolism (621) 621
molecular structure (577) 577
analysis (560) 560
dose-response relationship, drug (515) 515
enzymes (475) 475
cell line, tumor (461) 461
substrate specificity (444) 444
apoptosis (439) 439
cytochrome p-450 enzyme system - metabolism (433) 433
toxicology (430) 430
expression (426) 426
research (421) 421
chemistry, organic (403) 403
in-vitro (402) 402
inhibition (402) 402
coumarins - chemical synthesis (373) 373
cancer (367) 367
enzyme inhibitors - pharmacology (365) 365
chemistry, multidisciplinary (363) 363
cells (355) 355
rats, sprague-dawley (350) 350
in vitro techniques (344) 344
cell line (341) 341
binding sites (339) 339
derivatives (338) 338
physiological aspects (334) 334
cells, cultured (332) 332
fluorescence (321) 321
coumarins - therapeutic use (317) 317
proteins (312) 312
apoptosis - drug effects (310) 310
molecular sequence data (310) 310
identification (308) 308
models, molecular (303) 303
protein binding (303) 303
microsomes, liver - enzymology (297) 297
plant sciences (294) 294
liver - metabolism (293) 293
time factors (291) 291
amino acid sequence (290) 290
activation (282) 282
adult (281) 281
oxidative stress (278) 278
metabolites (270) 270
coumarins - isolation & purification (269) 269
cell survival - drug effects (267) 267
cell biology (265) 265
antineoplastic agents - pharmacology (263) 263
cytochrome p-450 cyp2a6 (262) 262
article (259) 259
mixed function oxygenases - metabolism (259) 259
coumarins - administration & dosage (251) 251
biophysics (250) 250
chromatography, high pressure liquid (250) 250
liver (250) 250
liver - enzymology (246) 246
cell proliferation - drug effects (244) 244
microsomes, liver - metabolism (243) 243
middle aged (243) 243
hydrogen-ion concentration (237) 237
oncology (234) 234
inhibitors (233) 233
plant extracts - pharmacology (231) 231
research article (226) 226
liver - drug effects (224) 224
drugs (223) 223
coumarins - pharmacokinetics (222) 222
rats, wistar (221) 221
chemistry (219) 219
mechanism (213) 213
chemistry, analytical (211) 211
spectrometry, fluorescence (209) 209
mass spectrometry (206) 206
fluorescent dyes - chemistry (205) 205
food science & technology (201) 201
oxidation-reduction (197) 197
hydrolysis (195) 195
flavonoids (193) 193
magnetic resonance spectroscopy (193) 193
coumarin derivatives (191) 191
antioxidants (190) 190
drug design (190) 190
human liver-microsomes (188) 188
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (6676) 6676
German (114) 114
Chinese (56) 56
French (38) 38
Russian (21) 21
Japanese (19) 19
Italian (16) 16
Czech (8) 8
Polish (7) 7
Spanish (6) 6
Dutch (2) 2
Hungarian (2) 2
Portuguese (2) 2
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 09/2012, Volume 342, Issue 3, pp. 654 - 664
Nodakenin, a coumarin isolated from the roots of Angelicae gigas, has been reported to possess neuroprotective, antiaggregatory, antibacterial, and... 
ACTIVATION | CYTOKINES | CYCLOOXYGENASE-2 | RAW264.7 CELLS | NITRIC-OXIDE SYNTHASE | KINASE | SEPTIC SHOCK | PHARMACOLOGY & PHARMACY | MEDIATORS | SEPSIS | ANGELICA-GIGAS | Transcription, Genetic - drug effects | Interleukin-6 - antagonists & inhibitors | Tumor Necrosis Factor-alpha - genetics | Male | NF-kappa B - metabolism | TNF Receptor-Associated Factor 6 - antagonists & inhibitors | Interleukin-1beta - genetics | Promoter Regions, Genetic - drug effects | Mitogen-Activated Protein Kinase Kinases - metabolism | Inflammation - metabolism | Phosphorylation - genetics | Drug Interactions | Ubiquitination - drug effects | Cyclooxygenase 2 - genetics | Interleukin-1beta - metabolism | Phosphorylation - drug effects | TNF Receptor-Associated Factor 6 - genetics | Interleukin-6 - metabolism | Interleukin-1beta - antagonists & inhibitors | NF-KappaB Inhibitor alpha | NF-kappa B - antagonists & inhibitors | Interleukin-6 - genetics | Anti-Inflammatory Agents - pharmacology | Dinoprostone - genetics | MAP Kinase Kinase Kinases - genetics | MAP Kinase Kinase Kinases - metabolism | Signal Transduction - genetics | Down-Regulation - genetics | Coumarins - pharmacology | Dinoprostone - metabolism | Macrophages - metabolism | Signal Transduction - drug effects | Nitric Oxide - genetics | Lipopolysaccharides - pharmacology | Mice | Transcription, Genetic - genetics | Dinoprostone - antagonists & inhibitors | Nitric Oxide Synthase Type II - metabolism | Tumor Necrosis Factor-alpha - metabolism | Mitogen-Activated Protein Kinase Kinases - genetics | Shock, Septic - prevention & control | I-kappa B Proteins - metabolism | I-kappa B Proteins - genetics | Shock, Septic - metabolism | I-kappa B Kinase - metabolism | I-kappa B Kinase - antagonists & inhibitors | Inflammation - drug therapy | Nitric Oxide Synthase Type II - antagonists & inhibitors | I-kappa B Proteins - antagonists & inhibitors | Shock, Septic - drug therapy | Glucosides - pharmacology | Nitric Oxide - antagonists & inhibitors | Mice, Inbred C57BL | Cells, Cultured | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | I-kappa B Kinase - genetics | Down-Regulation - drug effects | Animals | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Cyclooxygenase 2 - metabolism | TNF Receptor-Associated Factor 6 - metabolism | Inflammation - genetics | Macrophages - drug effects | Nitric Oxide - metabolism | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Ubiquitination - genetics
Journal Article
Molecular Nutrition and Food Research, ISSN 1613-4125, 03/2010, Volume 54, Issue 3, pp. 311 - 322
Epidemiology supports the important role of nutrition in prostate cancer (PCa) prevention. Pomegranate juice (PJ) exerts protective effects against PCa, mainly... 
Polyphenol | Ellagitannins | Bioavailability | Gene expression | Cancer | APOPTOSIS | CANCER CELLS | FOOD SCIENCE & TECHNOLOGY | CELL-CYCLE ARREST | CHEMOPREVENTION | HYPERPLASIA | P21 | GROWTH | GENE-EXPRESSION | CACO-2 CELLS | Coumarins - metabolism | Plant Extracts - chemistry | Prostatic Hyperplasia - urine | Prostatic Neoplasms - metabolism | Ellagic Acid - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Coumarins - chemistry | Male | Intracellular Signaling Peptides and Proteins - metabolism | RNA, Messenger - metabolism | Prostate - metabolism | Plant Extracts - administration & dosage | Juglans - chemistry | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Glucuronides - metabolism | Prostatic Neoplasms - urine | Hydrolyzable Tannins - chemistry | Biomarkers, Tumor - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Glucuronides - administration & dosage | Prostatic Neoplasms - prevention & control | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Beverages - analysis | Glucuronides - chemistry | Punicaceae - chemistry | Prostatic Neoplasms - surgery | Fruit - chemistry | Coumarins - administration & dosage | Ellagic Acid - chemistry | Rats | Glucuronides - urine | Nuclear Proteins - metabolism | Ellagic Acid - urine | Hydrolyzable Tannins - metabolism | Coumarins - urine | Proto-Oncogene Proteins c-myc - metabolism | Rats, Sprague-Dawley | Prostatic Hyperplasia - metabolism | Prostatic Hyperplasia - surgery | Hydrolyzable Tannins - administration & dosage | Animals | Intestines - microbiology | Aged | Proto-Oncogene Proteins c-myc - genetics
Journal Article
Phytomedicine, ISSN 0944-7113, 02/2014, Volume 21, Issue 3, pp. 240 - 246
Coumarins, also known as benzopyrones, are plant-derived products with several pharmacological properties, including antioxidant and anti-inflammatory... 
Inflammatory bowel disease | Antioxidant | Coumarin derivatives | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | 4-METHYLESCULETIN | INDUCTION | PLANT SCIENCES | TRINITROBENZENESULFONIC ACID MODEL | ESCULETIN | INFLAMMATORY-BOWEL-DISEASE | METABOLISM | GLUTATHIONE | INTEGRATIVE & COMPLEMENTARY MEDICINE | RAT COLITIS | SULFASALAZINE | PHARMACOLOGY & PHARMACY | Rats, Wistar | Glutathione - metabolism | Plant Extracts - pharmacology | Alkaline Phosphatase - metabolism | Colon - drug effects | Male | Esculin - therapeutic use | Biphenyl Compounds - metabolism | Inflammatory Bowel Diseases - metabolism | Esculin - pharmacology | Inflammation - metabolism | Lipid Peroxidation - drug effects | Anti-Inflammatory Agents - therapeutic use | Umbelliferones - therapeutic use | Phytotherapy | Inflammatory Bowel Diseases - prevention & control | Anti-Inflammatory Agents - pharmacology | Picrates - metabolism | Rats | Antioxidants - pharmacology | Inflammation - etiology | Colon - metabolism | Coumarins - therapeutic use | Coumarins - pharmacology | Umbelliferones - pharmacology | Antioxidants - therapeutic use | Colitis - etiology | Animals | Colitis - metabolism | Inflammation - prevention & control | Oxidative Stress - drug effects | Colitis - prevention & control | Plant Extracts - therapeutic use | Peroxidase - metabolism | Antioxidants | Coumarins | Care and treatment | Inflammation | Research | Health aspects
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 04/2012, Volume 109, Issue 15, pp. E869 - E878
IRE1 couples endoplasmic reticulum unfolded protein load to RNA cleavage events that culminate in the sequence-specific splicing of the Xbp1 mRNA and in the... 
High-throughput screening | 8-formyl-umbelliferone | Aldehydes | Reversible covalent inhibitor | Unfolded protein response | reversible covalent inhibitor | ACTIVATION | UNFOLDED-PROTEIN RESPONSE | ER-STRESS | MULTIDISCIPLINARY SCIENCES | high-throughput screening | KINASE | IRE1-ALPHA | TRANSCRIPTION FACTOR XBP-1 | ENDOPLASMIC-RETICULUM STRESS | CELL-SURVIVAL | unfolded protein response | aldehydes | IRE1 | TRANSMEMBRANE PROTEIN | Humans | Coumarins - chemistry | Endoribonucleases - antagonists & inhibitors | RNA, Messenger - metabolism | Ribonucleases - metabolism | X-Box Binding Protein 1 | DNA-Binding Proteins - metabolism | Ribonucleases - antagonists & inhibitors | Proteolysis - drug effects | Protein Binding - drug effects | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Lysine - metabolism | Membrane Proteins - metabolism | Binding Sites | Protein-Serine-Threonine Kinases - metabolism | RNA Splicing - drug effects | Endoribonucleases - metabolism | RNA, Messenger - genetics | Regulatory Factor X Transcription Factors | Coumarins - pharmacology | Transcription Factors - metabolism | Secretory Pathway - drug effects | Animals | Membrane Proteins - antagonists & inhibitors | Endoplasmic Reticulum Stress | Schiff Bases - chemistry | Mice | Schiff Bases - metabolism | Proteins | Molecules | Membranes | Ribonucleic acid--RNA | Cells | Biological Sciences | PNAS Plus
Journal Article
Biochimie, ISSN 0300-9084, 10/2013, Volume 95, Issue 10, pp. 1848 - 1854
Journal Article
Plant Physiology, ISSN 0032-0889, 1/2014, Volume 164, Issue 1, pp. 160 - 172
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 12/2007, Volume 5, Issue 12, pp. 2503 - 2511
Background:  Matrix Gla protein (MGP) is a small vitamin K‐dependent protein containing five γ‐carboxyglutamic acid (Gla) residues that are believed to be... 
matrix Gla protein | calcification | γ‐glutamyl carboxylation | vitamin K | coumarin | serine phosphorylation | Calcification | Coumarin γ-glutamyl carboxylation | Matrix Gla protein | Serine phosphorylation | Vitamin K | EXTRACELLULAR CALCIUM | gamma-glutamyl carboxylation | GAMMA-CARBOXYGLUTAMIC ACID | IN-VITRO | ARTERIES | OSTEOPONTIN | ELASTIC LAMELLAE | MINERALIZATION | VITAMIN-K | PERIPHERAL VASCULAR DISEASE | CORONARY-HEART-DISEASE | HEMATOLOGY | MORPHOGENETIC PROTEIN-2 | Phosphorylation | Muscle, Smooth, Vascular - metabolism | Calcium - metabolism | Humans | Middle Aged | Molecular Sequence Data | Male | Vitamin K 1 - pharmacology | Vitamin K - metabolism | Warfarin - pharmacology | Vitamin K - antagonists & inhibitors | Adult | Female | Cell Membrane - metabolism | Calcinosis - metabolism | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Extracellular Matrix Proteins - metabolism | Muscle, Smooth, Vascular - drug effects | Calcium-Binding Proteins - chemistry | Calcium-Binding Proteins - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Extracellular Matrix Proteins - chemistry | Peptide Fragments - metabolism | Cells, Cultured | 1-Carboxyglutamic Acid - metabolism | Serine - metabolism | Transport Vesicles - metabolism | Adolescent | Calcinosis - prevention & control | Protein Processing, Post-Translational | Serine | Anticoagulants (Medicine)
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 09/2013, Volume 59, pp. 428 - 437
Urolithins were the metabolites of ellagic acid by intestinal flora in gastrointestinal tract. In previous research, it was found that urolithins could mainly... 
Antiproliferative | Urolithin | Antioxidant | Ellagic acid | Apoptosis | OXIDATIVE STRESS | INDUCED APOPTOSIS | PHENOLIC-COMPOUNDS | FOOD SCIENCE & TECHNOLOGY | CACO-2 | P38 MAPK | P53 | JNK ACTIVATION | HEPATOCELLULAR-CARCINOMA | PATHWAY | TOXICOLOGY | EXPRESSION | Coumarins - metabolism | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Ellagic Acid - metabolism | Antioxidants - metabolism | Caspase 3 - chemistry | Humans | Urinary Bladder Neoplasms - enzymology | Caspase 3 - metabolism | p38 Mitogen-Activated Protein Kinases - biosynthesis | Neoplasm Proteins - metabolism | PPAR gamma - metabolism | Lipid Peroxidation - drug effects | Inhibitory Concentration 50 | Antineoplastic Agents, Phytogenic - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Urinary Bladder Neoplasms - metabolism | Ellagic Acid - pharmacology | Neoplasm Proteins - biosynthesis | p38 Mitogen-Activated Protein Kinases - genetics | Antioxidants - pharmacology | Urinary Bladder Neoplasms - drug therapy | Enterobacteriaceae - metabolism | Coumarins - pharmacology | Reactive Oxygen Species - antagonists & inhibitors | MAP Kinase Signaling System - drug effects | PPAR gamma - agonists | Cell Line, Tumor | Cell Proliferation - drug effects | Colon - microbiology | Oxidative Stress - drug effects | Antineoplastic Agents, Phytogenic - pharmacology | Methylation | Antioxidants | Metabolites | Bladder cancer | Index Medicus
Journal Article