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ISSN 0950-1991, 2017
Airway stem cells slowly self-renew and produce differentiated progeny to maintain homeostasis throughout the lifespan of an individual. Mutations in the... 
Cre-Lox | lung | mouse | trachea | progenitor
Journal Article
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 10/2016, Volume 854, pp. 725 - 730
Journal Article
Journal of Dental Research, ISSN 0022-0345, 8/2019, Volume 98, Issue 9, pp. 1002 - 1010
The identification and targeting of the molecular pathways regulating amelogenesis is an ongoing challenge in dental research, and progress has been restricted... 
calcium | CANDIDATE GENES | amelogenin | IDENTIFICATION | TOOTH | stromal interaction molecule 1 | dental enamel | Cre-Lox | CYTOKERATINS | DENTISTRY, ORAL SURGERY & MEDICINE | MINERALIZATION | ORAI1 | conditional knockout | EXPRESSION
Journal Article
Biology of Reproduction, ISSN 0006-3363, 7/2016, Volume 95, Issue 1
The mammalian target of rapamycin ( Mtor ) gene encodes a serine/threonine kinase that acts as a master regulator of processes as diverse as cell growth,... 
mTOR | spermatogenesis | Cre-lox | GJA1 | testicular degeneration | Sertoli cells
Journal Article
GLIA, ISSN 0894-1491, 06/2010, Volume 58, Issue 8, pp. 943 - 953
The lack of markers for astrocytes, particularly gray matter astrocytes, significantly hinders research into their development and physiological properties. We... 
Cre-lox | Spinal cord | Interneurons | Astrocytes | SVZ | Transgenic mice | Neural stem cells | Olfactory bulb | Radial glia | Fgfr3 | olfactory bulb | radial glia | transgenic mice | neural stem cells | astrocytes | spinal cord | interneurons
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 10/2003, Volume 17, Issue 13, pp. 2299 - 2299
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors exerting several functions in development and metabolism. The physiological functions... 
GAMMA | STEM-CELLS | fiber typing | BIOCHEMISTRY & MOLECULAR BIOLOGY | lipid metabolism | MOUSE | FATTY-ACIDS | CELL BIOLOGY | SKELETAL-MUSCLE | TRANSGENE EXPRESSION | PPAR-DELTA | GROWTH | BIOLOGY | hyperplasia | MICE | muscle development | Cre-Lox transgenesis | ADIPOSE
Journal Article
Kidney International, ISSN 0085-2538, 09/2019, Volume 96, Issue 3, pp. 597 - 611
Podocytes are differentiated post-mitotic cells that cannot replace themselves after injury. Glomerular parietal epithelial cells are proposed to be podocyte... 
Bowman’s capsule | Cre-lox | enhanced green fluorescent protein | FLP-FRT | tdTomato | transdifferentiation | reporter | focal segmental glomerulosclerosis | PROGENITOR CELLS | GLOMERULONEPHRITIS | RENIN LINEAGE | REGENERATION | INJURY | BOWMANS CAPSULE | EXPERIMENTAL FSGS | Bowman's capsule | MOUSE MODEL | DE-NOVO EXPRESSION | UROLOGY & NEPHROLOGY | PROTEINS | Index Medicus
Journal Article
Journal Article
Genes, ISSN 2073-4425, 05/2019, Volume 10, Issue 5, p. 374
Gene modification is a promising tool for plant breeding, and gradual application from the laboratory to the field. Selectable marker genes (SMG) are required... 
transgenic maize | egfp | recombination | cre/lox | marker-free | heat-shock
Journal Article
Frontiers in Neural Circuits, ISSN 1662-5110, 11/2013, Volume 7
Striatonigral and striatopallidal projecting medium spiny neurons (MSNs) express dopamine D1 (D1+) and D2 receptors (D2+), respectively. Both classes receive... 
GABA | Striatum | Patch-clamp | Cre-lox genetics | Tonic inhibition | tonic inhibition | patch-clamp
Journal Article
Frontiers in Cellular Neuroscience, ISSN 1662-5102, 07/2011, Volume 5, Issue JULY, pp. 15 - 15
The striatum is a key structure for movement control, but the mechanisms that dictate the output of distinct subpopulations of medium spiny projection neurons... 
GABA | Striatum | Patch-clamp | Cre-lox genetics | Tonic inhibition
Journal Article
OncoImmunology, ISSN 2162-4011, 06/2015, Volume 4, Issue 6, pp. e1008371 - e1008371
Journal Article
DEVELOPMENT, ISSN 0950-1991, 07/2004, Volume 131, Issue 14, pp. 3433 - 3444
The emerging evidence that stem cells develop in specialised niches highlights the potential role of environmental factors in their regulation. Here we examine... 
PROGENITOR CELLS | subventricular zone | stem cell niche | ventricular zone | MOUSE | NEUROEPITHELIAL CELLS | PROLIFERATION | DEVELOPMENTAL BIOLOGY | cre/lox | PRIMORDIAL GERM-CELLS | fibronectin | GROWTH | CNS PRECURSOR | laminin | CENTRAL-NERVOUS-SYSTEM | GENERATION | DIFFERENTIATION | extracellular matrix | neurosphere
Journal Article
DEVELOPMENTAL BIOLOGY, ISSN 0012-1606, 02/2008, Volume 314, Issue 2, pp. 406 - 417
The pdy1 gene is essential for pancreatic organogenesis in humans and mice; pdx1 mutations have been identified in human diabetic patients. Specific... 
PANCREATIC TRANSCRIPTION FACTOR | INSULIN PROMOTER | MOUSE PANCREAS | CHROMATIN STRUCTURE | BETA-CELLS | ISLET NEOGENESIS | DEVELOPMENTAL BIOLOGY | lineage tracing | islet | HOMEODOMAIN PROTEIN | Cre-lox | pancreas | EARLY-ONSET | CRE-MEDIATED RECOMBINATION | diabetes | II DIABETES-MELLITUS | Cell research | Glucose | Diabetes | Statistics | Dextrose
Journal Article
Molecules, ISSN 1420-3049, 2019, Volume 24, Issue 6, p. 1189
The genetic modification of the mouse genome using the cre-lox system has been an invaluable tool in deciphering gene and protein function in a temporal and/or... 
Mouse model | Dilated cardiomyopathy | Cardiac-specific-cre | Cardiotoxic | Cre-lox system | DNA damage | P38 MAP-KINASES | RECOMBINASE | cardiotoxic | ACTIVATION | mouse model | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART-FAILURE | DNA-DAMAGE | MOUSE | CHEMISTRY, MULTIDISCIPLINARY | ESTROGEN-RECEPTOR | DELETION | cre-lox system | HYPERTROPHY | EXPRESSION | cardiac-specific-cre | dilated cardiomyopathy
Journal Article
PLOS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2
Genetically relevant mouse models need to recapitulate the hallmarks of human disease by permitting spatiotemporal gene targeting. This is especially important... 
CRE/LOX RECOMBINATION | INACTIVATION | CYST FORMATION | DNA | MULTIDISCIPLINARY SCIENCES | CRE RECOMBINASE | MICE | KIDNEY | LINDAU TUMOR-SUPPRESSOR | MOUSE PROXIMAL TUBULE | EXPRESSION
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2019, Volume 1929, pp. 223 - 231
The calcineurin/nuclear factor of activated T-cell (NFAT) signaling pathway is important for the development and function of different leukocyte subsets.... 
Myeloid cells | Calcium | Dendritic cells | Granulocytes | Calcineurin | Cre/lox breeding | Macrophages | NFAT | Index Medicus
Journal Article
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