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Cell, ISSN 0092-8674, 08/2017, Volume 170, Issue 4, pp. 649 - 663.e13
Journal Article
Analytical Chemistry, ISSN 0003-2700, 03/2005, Volume 77, Issue 5, pp. 1282 - 1289
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e62068 - e62068
The NF-kappa B pathway plays an important role in chronic inflammatory and autoimmune diseases. Recently, NF-kappa B has also been suggested as an important... 
METABOLIC SYNDROME | OXIDATIVE STRESS | ACTIVATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | MESANGIAL CELLS | INDUCED INFLAMMATION | DIABETIC-NEPHROPATHY | BINDING-ACTIVITY | TRANSCRIPTION FACTOR | ADIPOSE-TISSUE | Albuminuria - complications | Diabetes Mellitus, Experimental - drug therapy | Liver - pathology | Triterpenes - pharmacology | Kidney - pathology | Glycated Hemoglobin A - metabolism | Triterpenes - therapeutic use | Kidney Glomerulus - physiopathology | Male | NF-kappa B - metabolism | Kidney Function Tests | Diabetes Mellitus, Experimental - blood | Adipose Tissue - metabolism | Albuminuria - physiopathology | Kidney - metabolism | Liver - drug effects | Lipids - blood | Inflammation Mediators - metabolism | Lipid Peroxidation - drug effects | Kidney Glomerulus - metabolism | Albuminuria - metabolism | Diabetes Mellitus, Experimental - metabolism | Fatty Acids - metabolism | Kidney - physiopathology | Diabetes Mellitus, Experimental - physiopathology | Albuminuria - pathology | NF-kappa B - antagonists & inhibitors | Kidney - drug effects | Podocytes - metabolism | Cytokines - metabolism | Kidney Glomerulus - drug effects | Liver - metabolism | Adipose Tissue - pathology | Cells, Cultured | Insulin Resistance | Kidney Glomerulus - pathology | Podocytes - pathology | Animals | Podocytes - drug effects | Mice | Oxidative Stress - drug effects | Adipose Tissue - drug effects | Transcription factors | Nephrology | Adipose tissue | Disease | Syngeneic grafts | Oxidative metabolism | Liver | Body weight | Neuropeptides | Adipocytes | Glucose | Animal tissues | Lipid metabolism | Stresses | Obesity | Medical research | NF-κB protein | Cytokines | Internal medicine | Mortality | Abnormalities | Polyamide-imides | Metabolism | Insulin | Fatty acids | Inhibitors | Nephropathy | Weight reduction | Metabolic disorders | Structure-function relationships | Oxidative stress | Animal models | Homeostasis | Adiponectin | Oxidation resistance | Rodents | Collagen (type IV) | Creatinine | Urine | Hypertension | Excretion | Fasting | Kidneys | Diabetes mellitus | Organs | Inflammation | Stress | Medicine | Insulin resistance | Diabetes | Autoimmune diseases | Index Medicus
Journal Article
Kidney International, ISSN 0085-2538, 09/2012, Volume 82, Issue 5, pp. 537 - 547
β-Catenin is a unique intracellular protein functioning as an integral component of the cell–cell adherens complex and a principal signaling protein mediating... 
β-catenin | apoptosis | acute kidney injury | Wnt | beta-catenin | INTEGRIN-LINKED KINASE | PROAPOPTOTIC BAX | GAMMA-CATENIN | MECHANISMS | PODOCYTE INJURY | EPITHELIAL-CELLS | UROLOGY & NEPHROLOGY | AMELIORATES PROTEINURIA | UP-REGULATION | RENAL INTERSTITIAL FIBROSIS | Reperfusion Injury - etiology | Wnt1 Protein - genetics | Phosphorylation | Epithelial Cells - metabolism | Cadherins - metabolism | Inhibitor of Apoptosis Proteins - genetics | Humans | Acute Kidney Injury - genetics | Wnt1 Protein - metabolism | Adherens Junctions - metabolism | Transfection | Time Factors | Acute Kidney Injury - chemically induced | Inhibitor of Apoptosis Proteins - metabolism | Kidney Tubules - pathology | Kidney Tubules - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | Repressor Proteins - metabolism | Disease Models, Animal | Folic Acid | Cell Line | Reperfusion Injury - pathology | Acute Kidney Injury - pathology | Mice, Inbred C57BL | beta Catenin - deficiency | Tumor Suppressor Protein p53 - metabolism | bcl-2-Associated X Protein - metabolism | gamma Catenin - metabolism | Repressor Proteins - genetics | Genotype | Survivin | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | Phenotype | Animals | Creatinine - blood | Mice | Acute Kidney Injury - metabolism | Apoptosis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e87936 - e87936
The growing incidence of chronic kidney disease remains a global health problem. Obesity is a major risk factor for type-2 diabetes and renal impairment.... 
CHRONIC HEART-FAILURE | TISSUE INFLAMMATION | ATRIAL-NATRIURETIC-PEPTIDE | WAIST CIRCUMFERENCE | GLUCOSE-METABOLISM | MULTIDISCIPLINARY SCIENCES | IN-VIVO | ENHANCES INSULIN SENSITIVITY | FACTOR-KAPPA-B | CHRONIC KIDNEY-DISEASE | HYPERTENSIVE-RATS | Tumor Necrosis Factor-alpha - metabolism | Atrial Natriuretic Factor - metabolism | Endothelin-1 - metabolism | Diabetic Nephropathies - metabolism | Rats | Male | Dinoprost - metabolism | Interleukins - metabolism | Hemin - metabolism | Rats, Zucker | Inflammation - metabolism | Kidney - metabolism | Macrophages - metabolism | Animals | Diabetic Nephropathies - physiopathology | Chemokine CCL3 - metabolism | Adiposity - physiology | Dinoprost - analogs & derivatives | Blood Glucose - metabolism | Heme Oxygenase (Decyclizing) - metabolism | Extracellular Matrix Proteins - metabolism | Kidney - physiopathology | Inflammation - physiopathology | Type 2 diabetes | Adipose tissues | Fibronectins | Obesity | Endothelin | Cytokines | Diabetic nephropathies | Macrophages | Risk factors | Glucose metabolism | Chronic kidney failure | Collagen | Heme | Natriuretic peptides | Adipose tissue | Syngeneic grafts | Selectivity | Adipocytes | Fibronectin | Proteins | Genotype & phenotype | Cyclic GMP | Fibroblasts | Physiology | Carbon monoxide | Public health | Pulmonary arteries | Endothelin 1 | Tumor necrosis factor-α | Metabolism | Gene expression | Studies | Oxygenase | Hemin | Nephropathy | Fibrosis | Interleukin 10 | Infiltration | Renal function | Paracrine signalling | Adiponectin | Interleukin 6 | Rodents | Diaphragm (anatomy) | Extracellular matrix | Tumor necrosis factor-TNF | Lesions | Inducers | Creatinine | Hypertension | Excretion | Kidneys | Diabetes mellitus | Markers | Health risks | Inflammation | Morbidity | Scaffolding | Insulin resistance | Diaphragm | Diabetes | Proteinuria | Index Medicus
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 05/2018, Volume 46, Issue 4, pp. 1628 - 1642
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 02/2013, Volume 65, Issue 2, pp. 243 - 252
Objectives To investigate the potential protective effects of captopril, the angiotensin-converting enzyme inhibitor, in diabetic rats exposed to... 
kidney | diabetes mellitus | ischaemia/reperfusion | rats | captopril | OXIDATIVE STRESS | OXIDANT STRESS | ISCHEMIA-REPERFUSION INJURY | RECEPTOR BLOCKER | CONVERTING ENZYME-INHIBITION | RENIN-ANGIOTENSIN SYSTEM | CARBON-MONOXIDE | PHARMACOLOGY & PHARMACY | HEME OXYGENASE-1 | DECREASES APOPTOSIS | BILIVERDIN REDUCTASE | Tumor Necrosis Factor-alpha - metabolism | Islets of Langerhans - drug effects | Diabetes Mellitus, Experimental - drug therapy | Fas Ligand Protein - metabolism | Kidney - blood supply | Captopril - pharmacology | Kidney - pathology | Glutathione - metabolism | Microtubule-Associated Proteins - metabolism | Caspase 3 - metabolism | Male | NF-kappa B - metabolism | Diabetes Mellitus, Type 2 - metabolism | Reperfusion Injury - blood | Creatinine - metabolism | Aldosterone - metabolism | Insulin-Secreting Cells - metabolism | Kidney - metabolism | Islets of Langerhans - metabolism | Hyperglycemia - pathology | Angiotensin-Converting Enzyme Inhibitors - pharmacology | Diabetes Mellitus, Experimental - metabolism | Heme Oxygenase (Decyclizing) - metabolism | Reperfusion Injury - metabolism | Kidney Diseases - metabolism | Malondialdehyde - metabolism | Kidney - drug effects | Islets of Langerhans - pathology | Reperfusion Injury - pathology | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Aldosterone - blood | Rats | Rats, Sprague-Dawley | Hyperglycemia - metabolism | Insulin - metabolism | Animals | Reperfusion Injury - prevention & control | Hyperglycemia - blood | Insulin-Secreting Cells - drug effects | Creatinine - blood | Diabetes Mellitus, Experimental - pathology | Diabetes Mellitus, Type 2 - pathology | Insulin-Secreting Cells - pathology | Diabetes Mellitus, Type 2 - drug therapy | Nitric Oxide - metabolism | Enzymes | Pancreatic beta cells | Enzyme inhibitors | Ischemia | Captopril | Nitric oxide | Heme | Diabetes | Rodents | Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2017, Volume 486, Issue 2, pp. 451 - 457
Klotho, an antiaging protein, can extend the lifespan and modulate cellular responses to inflammation and oxidative stress which can ameliorate chronic kidney... 
Cyclosporine A | PDLIM2 | Nephropathy | Klotho | NF-kB p65 | GLOMERULONEPHRITIS | OXIDATIVE STRESS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | BIOPHYSICS | DISEASE | MICE | KIDNEY | ANTIAGING GENE | RENAL INJURY | EXPRESSION | Tumor Necrosis Factor-alpha - metabolism | RNA, Small Interfering - genetics | Epithelial Cells - metabolism | Interleukin-12 - genetics | Blood Urea Nitrogen | Epithelial Cells - drug effects | Tumor Necrosis Factor-alpha - genetics | Glucuronidase - metabolism | Male | Cyclosporine | LIM Domain Proteins - metabolism | Transcription Factor RelA - genetics | Nephritis, Interstitial - metabolism | Nephritis, Interstitial - pathology | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Adenoviridae - genetics | Chemokine CCL2 - metabolism | Interleukin-6 - metabolism | Nephritis, Interstitial - chemically induced | Cell Line | Kidney Tubules, Proximal - pathology | Genetic Vectors - chemistry | Interleukin-6 - genetics | Macrophages - pathology | Signal Transduction | LIM Domain Proteins - antagonists & inhibitors | Gene Expression Regulation | Genetic Vectors - metabolism | Chemokine CCL2 - genetics | Epithelial Cells - pathology | Interleukin-12 - metabolism | Mice, Inbred ICR | Macrophages - metabolism | Animals | Glucuronidase - genetics | Nephritis, Interstitial - genetics | Nitric Oxide Synthase Type II - genetics | Transcription Factor RelA - metabolism | Adaptor Proteins, Signal Transducing - genetics | Kidney Tubules, Proximal - metabolism | Creatinine - blood | LIM Domain Proteins - genetics | Mice | Adenoviridae - metabolism | Glucuronidase - pharmacology | Adaptor Proteins, Signal Transducing - metabolism | Nitric Oxide Synthase Type II - metabolism | RNA, Small Interfering - metabolism | Medical research | Urea | Medical colleges | Chronic kidney failure | RNA | Luciferase | Medicine, Experimental | Index Medicus
Journal Article
Australasian Psychiatry, ISSN 1039-8562, 2008, Volume 42, Issue 6, pp. 467 - 477
Objective: Abnormalities of the anterior cingulate cortex (ACC) have consistently been identified in obsessive-compulsive disorder (OCD), but very few studies... 
Proton | Spectroscopy | Obsessive-compulsive | Glutamate | MRI | Sex | NEUROPSYCHOLOGY | PSYCHIATRY | sex | MAJOR DEPRESSION | obsessive-compulsive | OCD | MAGNETIC-RESONANCE-SPECTROSCOPY | METABOLISM | spectroscopy | CORTEX | RELEVANCE | PSYCHIATRIC-DISORDERS | PAROXETINE | glutamate | BRAIN | proton | Women | Obsessive-compulsive disorder | Research | Brain chemistry | Mental health | Biomarkers - metabolism | Choline - metabolism | Severity of Illness Index | Predictive Value of Tests | Magnetic Resonance Spectroscopy - methods | Inositol - metabolism | Humans | Obsessive-Compulsive Disorder - metabolism | Glutamine - metabolism | Male | Magnetic Resonance Spectroscopy - instrumentation | Gyrus Cinguli - metabolism | Neuropsychological Tests | Obsessive-Compulsive Disorder - diagnosis | Obsessive-Compulsive Disorder - drug therapy | Creatine - metabolism | Sex Factors | Adult | Aspartic Acid - metabolism | Female | Glutamic Acid - metabolism | Gyrus Cinguli - drug effects | Aspartic Acid - analogs & derivatives | Choline, metabolism | Obsessive-Compulsive Disorder, physiopathology | Obsessive-Compulsive Disorder, psychology | Inositol, metabolism | Magnetic Resonance Spectroscopy | Intelligence | Gyrus Cinguli, metabolism | Gyrus Cinguli, physiopathology | Creatinine, metabolism | Educational Status | Aspartic Acid, analogs and derivatives | Functional Laterality | Glutamates, metabolism | Magnetic Resonance Imaging | Obsessive-Compulsive Disorder | Obsessive-Compulsive Disorder, metabolism | Aspartic Acid, metabolism | Psychotropic Drugs, therapeutic use | Glutamine, metabolism | Index Medicus
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2019, Volume 144, Issue 5, pp. 947 - 956
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 04/2015, Volume 78, pp. 17 - 25
Cisplatin is an effective chemotherapeutic agent successfully used in the treatment of a wide range of solid tumors, while its usage is limited due to its... 
Interleukin 6 | Tumor necrosis factor-α | Ginseng | Tumor suppressor P53 | DNA damage | Cisplatin | Tumor suppressor p53 | APOPTOSIS | ACTIVATION | ACID | PANAX-GINSENG | FOOD SCIENCE & TECHNOLOGY | Tumor necrosis factor-alpha | METABOLISM | ANTIOXIDANT | ENZYMES | LIVER | TOXICOLOGY | INDUCED NEPHROTOXICITY | EXTRACT | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Kidney - pathology | Apoptosis - drug effects | Glutathione - metabolism | Tumor Necrosis Factor-alpha - genetics | Male | Urea - blood | Tumor Suppressor Protein p53 - genetics | Cisplatin - administration & dosage | Plant Preparations - pharmacology | Kidney Diseases - chemically induced | DNA Fragmentation - drug effects | Xanthine Oxidase - genetics | Interleukin-6 - metabolism | Superoxide Dismutase - metabolism | Glutathione Peroxidase - metabolism | Xanthine Oxidase - metabolism | Kidney - drug effects | Interleukin-6 - genetics | Kidney Diseases - pathology | Tumor Suppressor Protein p53 - metabolism | Adenosine Triphosphatases - metabolism | Glutathione Transferase - metabolism | Kidney Diseases - drug therapy | Rats | Thiobarbituric Acid Reactive Substances - metabolism | Kidney - cytology | Rats, Sprague-Dawley | Catalase - metabolism | Animals | Panax - chemistry | Cisplatin - adverse effects | Creatinine - blood | Adenosine Triphosphatases - genetics | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Serum Albumin - metabolism | Index Medicus
Journal Article