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PLoS ONE, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, p. e0142176
The effects of indigestible carbohydrates, protein type, and protein level on large intestine health were examined in rats. For 21 days, 12 groups of six... 
BETA-GLUCURONIDASE ACTIVITY | YOUNG-PIGS | RED MEAT | RESISTANT STARCH | POTATO FIBER | DIETARY FIBER | BACTERIAL METABOLITES | MULTIDISCIPLINARY SCIENCES | CECAL FERMENTATION | ADULT DOGS | COLONIC DNA-DAMAGE | Propionates - metabolism | Body Weight | Pectins - metabolism | Rats, Wistar | Glucuronidase - metabolism | Starch - metabolism | Nutritional Physiological Phenomena | Dietary Carbohydrates - metabolism | Fatty Acids, Volatile - metabolism | Dietary Proteins - metabolism | Intestine, Large - metabolism | Phenol - metabolism | Dietary Proteins - pharmacology | Acetic Acid - metabolism | Biomarkers - metabolism | Starch - pharmacology | Ammonia - metabolism | Colon - pathology | Dietary Carbohydrates - pharmacology | Cecum - drug effects | Colon - metabolism | Cresols - metabolism | Cecum - pathology | Pectins - pharmacology | Animals | DNA Damage | Cellulose - pharmacology | Cellulose - metabolism | Hydrogen-Ion Concentration | Ammonia | Genetic aspects | Research | Casein | Potatoes | DNA damage | Cellulose | pH effects | Metabolites | Rodents | pH | Bioindicators | Colon | Damage | Deoxyribonucleic acid--DNA | Carbohydrates | Nutrition | Starch | Propionic acid | Cecum | Rats | Pectin | Fermentation | Fatty acids | Diet | Large intestine | Weight reduction | Phenols | Biomarkers | Dietary fiber | Acetic acid | Deoxyribonucleic acid | DNA
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2009, Volume 106, Issue 34, pp. 14728 - 14733
We provide a demonstration in humans of the principle of pharmacometabonomics by showing a dear connection between an individual's metabolic phenotype, in the... 
Urine | Metabolomics | Excretion | Pharmacogenetics | Metabolites | Metabolic diseases | Bacteria | Glucuronides | Sulfates | Metabolism | Sulfate | Acetaminophen | p-cresol | Glucuronide | DNA-ADDUCTS | sulfate | QUINONE METHIDE | bacteria | MULTIDISCIPLINARY SCIENCES | ACETAMINOPHEN HEPATOTOXICITY | MYELIN BASIC-PROTEIN | acetaminophen | AUTISTIC-CHILDREN | GUT MICROFLORA | glucuronide | LOW-DOSE PARACETAMOL | PHARMACOGENOMICS | P-CRESOL SULFATE | HUMAN SULFOTRANSFERASES | Acetaminophen - metabolism | Analgesics, Non-Narcotic - pharmacokinetics | Humans | Middle Aged | Male | Sulfuric Acid Esters - metabolism | Young Adult | Bacteria - growth & development | Cresols - urine | Adult | Bacteria - metabolism | Acetaminophen - analogs & derivatives | Sulfates - metabolism | Magnetic Resonance Spectroscopy | Administration, Oral | Gastrointestinal Tract - microbiology | Acetaminophen - urine | Analgesics, Non-Narcotic - administration & dosage | Analgesics, Non-Narcotic - metabolism | Cresols - metabolism | Gastrointestinal Tract - metabolism | Host-Pathogen Interactions | Sulfuric Acid Esters - urine | Adolescent | Acetaminophen - pharmacokinetics | Host-bacteria relationships | Drug metabolism | Metabonomic analysis | Research | Competition | Drugs | biomarkers | Cresol | Magnetic resonance spectroscopy | p-Cresol | Analgesics | Sulfonation | Xenobiotics | Digestive tract | Pharmaceuticals | Biological Sciences
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 12/2013, Volume 24, Issue 1, pp. 88 - 99
Journal Article
Journal Article
Archives of Medical Research, ISSN 0188-4409, 2014, Volume 45, Issue 4, pp. 309 - 317
Journal Article
Kidney International, ISSN 0085-2538, 04/2013, Volume 83, Issue 4, pp. 582 - 592
The accumulation of -cresyl sulfate (PCS), a uremic toxin, is associated with the mortality rate of chronic kidney disease patients; however, the biological... 
p-cresyl sulfate | chronic kidney disease | uremic toxins | indoxyl sulfate | NADPH oxidase | oxidative stress | KAPPA-B | ORGANIC ANION TRANSPORTERS | FAILURE | CRESYLSULPHATE | ENDOTHELIAL-CELLS | UROLOGY & NEPHROLOGY | SMOOTH-MUSCLE-CELLS | CHRONIC KIDNEY-DISEASE | EXPRESSION | Cresols - toxicity | Reactive Oxygen Species - metabolism | Epithelial Cells - drug effects | Humans | Transforming Growth Factor beta1 - metabolism | NADPH Oxidases - metabolism | Male | Sulfuric Acid Esters - toxicity | RNA, Messenger - metabolism | Dose-Response Relationship, Drug | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Transfection | Nephrectomy | RNA Interference | Inflammation Mediators - metabolism | Renal Insufficiency, Chronic - genetics | NADPH Oxidases - genetics | Kidney Tubules, Proximal - enzymology | Cytokines - genetics | Cell Line | Cell Survival - drug effects | Kidney Tubules, Proximal - pathology | Collagen Type I - metabolism | Cytokines - metabolism | Probenecid - pharmacology | Rats | Epithelial Cells - pathology | NADPH Oxidase 4 | Renal Insufficiency, Chronic - enzymology | Rats, Sprague-Dawley | Renal Insufficiency, Chronic - pathology | Animals | Epithelial Cells - enzymology | Fibrosis | Enzyme Activation | Oxidative Stress - drug effects | Renal Insufficiency, Chronic - chemically induced | Kidney Tubules, Proximal - drug effects | Index Medicus
Journal Article
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 2013, Volume 24, Issue 12, pp. 1981 - 1994
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 03/2008, Volume 190, Issue 5, pp. 1620 - 1630
Journal Article
Journal Article