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Hypertension, ISSN 0194-911X, 09/2004, Volume 44, Issue 3, pp. 271 - 276
Journal Article
Journal of Vascular Surgery, ISSN 0741-5214, 2007, Volume 45, Issue 2, pp. 373 - 380
Background Varicose veins are a common disorder of extensive venous dilation and remodeling with an as-yet unclear mechanism. Studies have shown increased... 
Surgery | SURGERY | GENERAL-POPULATION | ABDOMINAL AORTIC-ANEURYSMS | ENDOTHELIAL-CELLS | NITRIC-OXIDE | SAPHENOUS-VEIN | MATRIX-METALLOPROTEINASE-9 | INSUFFICIENCY | PERIPHERAL VASCULAR DISEASE | ARTERIOLAR VASODILATION | VASCULAR SMOOTH-MUSCLE | EDINBURGH VEIN | Epoprostenol - metabolism | Muscle, Smooth, Vascular - metabolism | Nitric Oxide Synthase - antagonists & inhibitors | Endothelium, Vascular - drug effects | Male | Potassium Channels - metabolism | Phenylephrine - pharmacology | Varicose Veins - metabolism | Potassium Chloride - pharmacology | Vasodilator Agents - metabolism | Potassium Channels, Calcium-Activated - metabolism | Dilatation, Pathologic | Matrix Metalloproteinase 2 - pharmacology | Potassium Channel Blockers - pharmacology | Muscle, Smooth, Vascular - drug effects | NG-Nitroarginine Methyl Ester - pharmacology | Vasoconstrictor Agents - pharmacology | Vasodilator Agents - pharmacology | Matrix Metalloproteinase 2 - metabolism | Varicose Veins - physiopathology | Enzyme Inhibitors - pharmacology | Rats | Vena Cava, Inferior - metabolism | Varicose Veins - pathology | Potassium Channels - drug effects | Indomethacin - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Peptides - pharmacology | Animals | Large-Conductance Calcium-Activated Potassium Channel alpha Subunits | Endothelium, Vascular - metabolism | Vasodilation - drug effects | Cromakalim - pharmacology | In Vitro Techniques | Nitric Oxide - metabolism
Journal Article
Science, ISSN 0036-8075, 10/1997, Volume 278, Issue 5335, pp. 114 - 117
Journal Article
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2007, Volume 293, Issue 6, pp. 3246 - 3253
Acute intravenous Tempol reduces mean arterial pressure (MAP) and heart rate (HR) in spontaneously hypertensive rats. We investigated the hypothesis that the... 
Nitric oxide synthase | Superoxide dismutase | Adenosine 5′-triphosphate-activated potassium channels | Catalase | Sympathetic nervous system | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | POTASSIUM CHANNELS | sympathetic nervous system | SENSITIVE K+ CHANNELS | NITRIC-OXIDE SYNTHESIS | BLOOD-PRESSURE | adenosine 5 '-triphosphate-activated potassium channels | CALCIUM INFLUX | DOCA-SALT RATS | superoxide dismutase | ENDOTHELIAL-CELLS | SYMPATHETIC-NERVE ACTIVITY | PERIPHERAL VASCULAR DISEASE | HYDROGEN-PEROXIDE | nitric oxide synthase | catalase | Amitrole - pharmacology | Buthionine Sulfoximine - pharmacology | Antihypertensive Agents - pharmacology | Large-Conductance Calcium-Activated Potassium Channels - metabolism | Sympathetic Nervous System - drug effects | Catalase - antagonists & inhibitors | Glutathione Peroxidase - antagonists & inhibitors | Antihypertensive Agents - administration & dosage | Nitric Oxide Synthase - antagonists & inhibitors | Hypertension - drug therapy | Male | Large-Conductance Calcium-Activated Potassium Channels - antagonists & inhibitors | Cyclic N-Oxides - administration & dosage | Ganglionic Blockers - pharmacology | Spin Labels | Sympathetic Nervous System - physiopathology | Metalloporphyrins - pharmacology | Sympathetic Nervous System - metabolism | Dose-Response Relationship, Drug | Heart Rate - drug effects | Hexamethonium - pharmacology | KATP Channels - drug effects | Glyburide - pharmacology | Time Factors | Cyclic N-Oxides - pharmacology | Blood Pressure - drug effects | Heme Oxygenase (Decyclizing) - antagonists & inhibitors | Heme Oxygenase (Decyclizing) - metabolism | Potassium Channel Blockers - pharmacology | Disease Models, Animal | NG-Nitroarginine Methyl Ester - pharmacology | Rats, Inbred SHR | Glutathione Peroxidase - metabolism | Enzyme Inhibitors - pharmacology | Rats | Hypertension - physiopathology | Hypertension - metabolism | Peptides - pharmacology | Catalase - metabolism | KATP Channels - metabolism | Animals | Nitric Oxide Synthase - metabolism | Infusions, Intravenous | Cromakalim - pharmacology | Nitric Oxide - metabolism
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2004, Volume 141, Issue 1, pp. 183 - 193
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2006, Volume 532, Issue 1, pp. 107 - 114
Partial bladder outlet obstruction of the pig is considered as a valuable preclinical model for evaluating the profile of compounds for the treatment of... 
Smooth muscle relaxation | Detrusor smooth muscle | Outlet obstruction | ATP-sensitive potassium channels | Sulfonylurea receptor | Potassium channel opener | Overactive bladder | smooth nvusclc relaxation | DETRUSOR MUSCLE | INSTABILITY | ATROPINE | sulfonylurea receptor | RATS | outlet obstruction | (-)-(9S)-9-(3-BROMO-4-FLUOROPHENYL)-2,3,5,6,7,9-HEXAHYDROTHIENO<3,2-B>QUINOLIN- 1,1-DIOXIDE A-278637 | MODEL | potassium channel opener | OUTFLOW OBSTRUCTION | PHARMACOLOGY & PHARMACY | RABBIT | CHANNEL OPENERS | detrusor smooth muscle | overactive bladder | Diazoxide - pharmacology | Electric Stimulation | Urinary Bladder Neck Obstruction - physiopathology | Potassium Channels - physiology | Benzophenones - pharmacology | Guanidines - pharmacology | Quinolones - pharmacology | Urinary Bladder - pathology | Serotonin - pharmacology | Adenosine Triphosphate - pharmacology | Dose-Response Relationship, Drug | Muscle, Smooth - drug effects | Swine | Potassium Chloride - pharmacology | Female | Cyclic S-Oxides - pharmacology | Cholinergic Agonists - pharmacology | Amides - pharmacology | Vasodilator Agents - pharmacology | Histamine - pharmacology | Carbachol - pharmacology | Animals | Serotonin Agents - pharmacology | Muscle Contraction - drug effects | Muscle Contraction - physiology | Muscle, Smooth - physiopathology | Potassium Channels - agonists | Urinary Bladder - physiopathology | Urinary Bladder - drug effects | Pyridines - pharmacology | Cromakalim - pharmacology | In Vitro Techniques | Hypertrophy | Analysis | Chemical properties
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2001, Volume 276, Issue 36, pp. 33369 - 33374
Protection of heart against ischemia-reperfusion injury by ischemic preconditioning and K ATP channel openers is known to involve the mitochondrial... 
PROTEIN-KINASE-C | CATION-TRANSPORT | ADENINE-NUCLEOTIDES | BEEF-HEART MITOCHONDRIA | BIOCHEMISTRY & MOLECULAR BIOLOGY |