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Journal Article
Carbohydrate polymers, ISSN 0144-8617, 2018, Volume 202, pp. 246 - 257
•Highly strength hydrogels were prepared based on natural polysaccharide chitosan.•Chitosan can endow multi-network hydrogels with good antimicrobial... 
Anti microbial | Chitosan | Hydrogel | Zwitterions | Cell anti-adhesion | POLYMER SCIENCE | HIGH-TOUGHNESS | DRUG-DELIVERY | CROSS-LINKING | CHEMISTRY, ORGANIC | PHYSICAL HYDROGELS | SILVER NANOPARTICLES | QUATERNARY AMMONIUM | ANTIBACTERIAL PROPERTIES | CHITIN HYDROGELS | COTTON FABRICS | ZWITTERIONIC HYDROGELS | CHEMISTRY, APPLIED | NIH 3T3 Cells | Biocompatible Materials - chemistry | Cross-Linking Reagents - pharmacology | Escherichia coli - drug effects | Hydrogels - chemical synthesis | Cross-Linking Reagents - chemical synthesis | Biocompatible Materials - chemical synthesis | Microbial Sensitivity Tests | Acrylates - pharmacology | Anti-Bacterial Agents - chemistry | Surface Properties | Chitosan - pharmacology | Acrylates - chemical synthesis | Molecular Structure | Cell Survival - drug effects | Cross-Linking Reagents - chemistry | Acrylates - chemistry | Polymers - chemical synthesis | Biocompatible Materials - pharmacology | Cell Adhesion - drug effects | Anti-Bacterial Agents - chemical synthesis | Particle Size | Animals | Chitosan - chemistry | Polymers - pharmacology | Polymers - chemistry | Anti-Bacterial Agents - pharmacology | Mice | Hydrogels - pharmacology | Staphylococcus aureus - drug effects | Hydrogels - chemistry | Mechanical properties | Polysaccharides | Crosslinked polymers | Biomedical engineering
Journal Article
Journal Article
Carbohydrate polymers, ISSN 0144-8617, 02/2018, Volume 181, pp. 668 - 674
•Injectable and in-situ crosslinkable glycol chitosan-based hydrogels were fabricated via blue-light illumination.•The glycol chitosan hydrogel provides strong... 
Glycol chitosan | Photochemical crosslinking | Hydrogel | Tissue adhesive | Antibacterial | Hemostasis | SEALANTS | POLYMER SCIENCE | CHEMISTRY, ORGANIC | INJECTABLE CHITOSAN | CARTILAGE | IN-VITRO | POLYMER | BIOMATERIALS | DRESSINGS | SKIN | CHEMISTRY, APPLIED | FIBRINOGEN | Cross-Linking Reagents - radiation effects | Staphylococcus epidermidis - drug effects | Escherichia coli - drug effects | Phenylpropionates - chemistry | Tissue Adhesives - pharmacology | Drug Carriers - toxicity | Hemostatics - pharmacology | Elastic Modulus | Hydrogels - chemical synthesis | Drug Carriers - chemistry | Gentamicins - pharmacology | Swine | Light | Phenylpropionates - toxicity | Tissue Adhesives - chemical synthesis | Chitosan - pharmacology | Hydrogels - toxicity | Chitosan - radiation effects | Phenylpropionates - radiation effects | Chitosan - chemical synthesis | Cell Line | Hemostatics - chemistry | Hemostatics - toxicity | Cross-Linking Reagents - chemistry | Cross-Linking Reagents - toxicity | Drug Carriers - chemical synthesis | Chitosan - toxicity | Organometallic Compounds - radiation effects | Drug Carriers - pharmacology | Animals | Amoxicillin - pharmacology | Chickens | Tissue Adhesives - toxicity | Drug Liberation | Anti-Bacterial Agents - pharmacology | Mice | Hemostatics - chemical synthesis | Hydrogels - pharmacology | Tissue Adhesives - chemistry | Hydrogels - chemistry | Crosslinked polymers | Glycols | Adhesives | Antibacterial agents | Analysis | Liver
Journal Article
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 186 - 8
Journal Article
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2002, Volume 417, Issue 6886, pp. 254 - 259
Journal Article
Biochemical journal, ISSN 1470-8728, 2002, Volume 367, Issue 2, pp. 541 - 548
Opening of the mitochondrial permeability transition pore (MPTP) is sensitized to [Ca2+] by oxidative stress (diamide) and phenylarsine oxide (PAO). We have... 
2 SEPARATE SITES | cyclophilin D | cell death | BIOCHEMISTRY & MOLECULAR BIOLOGY | PYRIDINE-NUCLEOTIDES | apoptosis | ADP/ATP CARRIER | RAT-LIVER MITOCHONDRIA | CELL-DEATH | phenylarsine oxide | TRANSPORT ACTIVITY | CYSTEINE RESIDUES | N-ETHYLMALEIMIDE | oxidative stress | HEART-MITOCHONDRIA | diamide
Journal Article
Journal Article
Clinical cancer research, ISSN 1557-3265, 2005, Volume 11, Issue 20, pp. 7508 - 7515
Purpose: BRCA2, FANCC , and FANCG gene mutations are present in a subset of pancreatic cancer. Defects in these genes could lead to hypersensitivity to... 
BRCA1, BRCA2 | Xenograft models | DNA damage and repair mechanisms | Pharmacogenetics/pharmacogenomics | Gastrointestinal cancers: other | GENE-MUTATIONS | LUNG-CANCER | FUNCTIONAL-ACTIVITY | ONCOLOGY | ABL TYROSINE KINASE | MITOMYCIN-C | PANCREATIC-CANCER | RANDOMIZED-TRIAL | PHASE-II | COMPLEMENTATION GROUP | CARCINOMA | Paclitaxel - pharmacology | Apoptosis - drug effects | Cross-Linking Reagents - pharmacology | Humans | Deoxycytidine - pharmacology | Chlorambucil - pharmacology | Fanconi Anemia Complementation Group C Protein - genetics | Dose-Response Relationship, Drug | Pancreatic Neoplasms - drug therapy | Caspases - metabolism | Fanconi Anemia Complementation Group G Protein - genetics | Time Factors | Cross-Linking Reagents - therapeutic use | Fanconi Anemia Complementation Group G Protein - deficiency | Inhibitory Concentration 50 | Female | Antineoplastic Agents - pharmacology | Melphalan - pharmacology | Cell Survival - drug effects | Fanconi Anemia Complementation Group Proteins - deficiency | Mitomycin - therapeutic use | Pancreatic Neoplasms - pathology | Fanconi Anemia Complementation Group Proteins - genetics | Etoposide - pharmacology | Pancreatic Neoplasms - genetics | Cisplatin - pharmacology | Xenograft Model Antitumor Assays - methods | Mitomycin - pharmacology | Animals | Mice, Nude | Cell Line, Tumor | Fanconi Anemia Complementation Group C Protein - deficiency | BRCA2 Protein - deficiency | Fluorouracil - pharmacology | Mice | Vinblastine - pharmacology | Mutation | Cell Cycle - drug effects | BRCA2 Protein - genetics | Deoxycytidine - analogs & derivatives | Doxorubicin - pharmacology
Journal Article
Cancer Treatment Reviews, ISSN 0305-7372, 2015, Volume 42, pp. 3 - 9
Highlights • Regulatory T cells and effector T cells have a differential capacity to detoxify cyclophosphamide metabolites. • Gut microbiota plays an important... 
Hematology, Oncology and Palliative Medicine | Acrolein | Cyclophosphamide | Chemotherapy | T cells | GSH | DNA CROSS-LINKING | ALDEHYDE DEHYDROGENASE | FACILITATED ADOPTIVE IMMUNOTHERAPY | OVARIAN-CANCER | ANTITUMOR-ACTIVITY | BREAST-CANCER | HEMATOPOIETIC PROGENITOR CELLS | CANCER-PATIENTS | REACTIVE OXYGEN | ONCOLOGY | NF-KAPPA-B | Neoplasms - metabolism | Prodrugs - administration & dosage | T-Lymphocyte Subsets - immunology | Cyclophosphamide - administration & dosage | Oxidative Stress | Cross-Linking Reagents - pharmacology | Humans | Antineoplastic Agents, Alkylating - pharmacology | Antineoplastic Agents, Alkylating - administration & dosage | T-Lymphocytes, Regulatory - immunology | Dose-Response Relationship, Drug | T-Lymphocyte Subsets - drug effects | Adenosine Triphosphate - metabolism | Biotransformation | Neoplasms, Experimental - immunology | Cytotoxicity, Immunologic - drug effects | Acrolein - pharmacology | Drug Administration Schedule | Antineoplastic Agents, Alkylating - pharmacokinetics | Cross-Linking Reagents - administration & dosage | Neoplasms - drug therapy | T-Lymphocytes, Regulatory - drug effects | Animals | Prodrugs - pharmacokinetics | Neoplasms - immunology | Cyclophosphamide - pharmacology | Cyclophosphamide - pharmacokinetics | DNA Damage | Cell Cycle - drug effects | Neoplasms, Experimental - drug therapy | Prodrugs - pharmacology | Microbiota (Symbiotic organisms)
Journal Article