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ctbp (228) 228
animals (208) 208
humans (191) 191
biochemistry & molecular biology (178) 178
index medicus (156) 156
dna-binding proteins - metabolism (152) 152
cell biology (146) 146
protein binding (110) 110
dna-binding proteins - genetics (99) 99
repressor proteins - metabolism (95) 95
corepressor ctbp (81) 81
alcohol oxidoreductases - metabolism (79) 79
mice (79) 79
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transcription factors - metabolism (74) 74
transcription, genetic (74) 74
proteins (70) 70
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expression (66) 66
molecular sequence data (62) 62
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repressor proteins - genetics (62) 62
amino acid sequence (61) 61
transcription (59) 59
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transcriptional repression (55) 55
cellular phosphoprotein (53) 53
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oncology (53) 53
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article (51) 51
alcohol oxidoreductases - genetics (50) 50
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genetic aspects (48) 48
protein (48) 48
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repression (45) 45
dna-binding proteins - chemistry (42) 42
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biophysics (41) 41
cancer (41) 41
protein structure, tertiary (40) 40
genetics & heredity (39) 39
gene-expression (38) 38
developmental biology (37) 37
drosophila ctbp (37) 37
co-repressor (36) 36
phosphoproteins - genetics (36) 36
cell line, tumor (35) 35
cells (34) 34
complex (34) 34
nuclear proteins - metabolism (34) 34
promoter regions, genetic (33) 33
transformation (33) 33
corepressor (32) 32
physiological aspects (32) 32
transcriptional corepressor (32) 32
transcription factors (31) 31
cells, cultured (30) 30
activation (29) 29
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carrier proteins - metabolism (29) 29
female (29) 29
terminal-binding-protein (29) 29
adenovirus e1a (28) 28
domain (28) 28
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amino acid motifs (27) 27
chromatin (27) 27
genes (27) 27
signal transduction (27) 27
analysis (26) 26
c-terminal binding protein (26) 26
drosophila (26) 26
histone deacetylase (26) 26
binding (25) 25
cos cells (25) 25
transfection (25) 25
differentiation (24) 24
drosophila proteins - metabolism (24) 24
e1a (24) 24
genetic transcription (24) 24
molecular biology (24) 24
zinc-finger protein (24) 24
ctbp/bars (23) 23
homeodomain proteins - metabolism (23) 23
nuclear proteins - genetics (23) 23
acetylation (22) 22
base sequence (22) 22
binding-protein (22) 22
terminal binding-protein (22) 22
ctbp protein (21) 21
gene expression regulation, developmental (21) 21
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blotting, western (20) 20
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FEBS letters, ISSN 0014-5793, 1/2017, Volume 591, Issue 1, pp. 205 - 212
The mechanism underlying transcriptional coactivation by the co-repressor CtBP is not established. We previously found that CtBP co-occupies several actively... 
NeuroD1 | CtBP
Journal Article
FASEB Journal, ISSN 0892-6638, 12/2018, Volume 32, Issue 12, pp. 6423 - 6435
Unlike lower organisms, mammals have 2 C-terminal binding protein (Ctbp) isoforms, Ctbp1 and Ctbp2. Ctbp2 is revealed as a key factor involved in determining... 
Protein quantity | ESC differentiation | Ctbp isoforms | CORE | NETWORK | ACTIVATION | COMPLEX | COREPRESSOR CTBP | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | CELL BIOLOGY | protein quantity | NUCLEAR-LOCALIZATION | CTBP FAMILY PROTEINS | GENES | BIOLOGY | DIFFERENTIATION
Journal Article
11/2010
C-terminal Binding Protein (CtBP) is a transcriptional co-repressor that plays an important role in mammalian development and tumorigenesis. CtBP is known to... 
Chromatin Remodeling | Ikaros | Pituitary | 0307 | CtBP
Dissertation
Chemical Science, ISSN 2041-6520, 07/2013, Volume 4, Issue 8, pp. 3046 - 3057
Identification of direct modulators of transcription factor protein-protein interactions is a key challenge for ligand discovery that promises to significantly... 
CTBP | GLYCOLYSIS | CTBP/BARS | TRANSCRIPTIONAL COREPRESSOR | COACTIVATOR | ACTIVATION | INSTABILITY | ROLES | PROLIFERATION | TUMORIGENESIS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 06/2017, Volume 16, Issue 6, pp. 981 - 990
Transcriptional corepressor proteins have emerged as an important facet of cancer etiology. These corepressor proteins are often altered by loss-or... 
OVARIAN-CANCER CELLS | EARLY REGION 1A | TERMINAL-BINDING-PROTEIN | HISTONE DEACETYLASES | ONCOLOGY | GENE-EXPRESSION | CO-REPRESSOR | ADENOVIRUS E1A | VITAMIN-D-RECEPTOR | TUMOR-SUPPRESSOR | TRANSCRIPTIONAL COREPRESSOR CTBP | Neoplasms - metabolism | Humans | Antineoplastic Agents - therapeutic use | Structure-Activity Relationship | Molecular Targeted Therapy | Alcohol Oxidoreductases - genetics | DNA-Binding Proteins - metabolism | Multiprotein Complexes - metabolism | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Alcohol Oxidoreductases - antagonists & inhibitors | Carrier Proteins - chemistry | Antineoplastic Agents - pharmacology | Repressor Proteins - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Signal Transduction | Gene Expression Regulation | Repressor Proteins - genetics | Alcohol Oxidoreductases - metabolism | DNA-Binding Proteins - genetics | Cell Transformation, Neoplastic - metabolism | DNA-Binding Proteins - chemistry | Neoplasms - drug therapy | Animals | Carrier Proteins - metabolism | Alcohol Oxidoreductases - chemistry | Protein Binding | Cell Transformation, Neoplastic - drug effects | Neoplasms - pathology | Proteins | Cell survival | Mesenchyme | Transcription | Etiology | Mutation | Gene expression | Tissues | Cell migration | Cancer | transcriptional co-repressors | therapeutic targets | cancer hallmarks | CtBP inhibitors | CtBP
Journal Article
Molecular Oncology, ISSN 1574-7891, 08/2018, Volume 12, Issue 8, pp. 1358 - 1373
The carboxyl‐terminal binding proteins (CtBP) are transcriptional corepressors that regulate the expression of multiple epithelial‐specific and pro‐apoptotic... 
cell‐penetrating peptides | transcriptional corepressors | CtBP inhibitors | CtBP | cell-penetrating peptides | COREPRESSOR CTBP | VITAMIN-D-RECEPTOR | E-CADHERIN | BREAST-CANCER | TERMINAL-BINDING-PROTEIN | MELANOMA | ONCOLOGY | GROWTH | NEGATIVE MODULATION | EXPRESSION
Journal Article
Journal Article
Molecular pharmacology, ISSN 0026-895X, 07/2019, Volume 96, Issue 1, pp. 99 - 108
C-terminal binding proteins (CtBP1/2) are oncogenic transcriptional coregulators and dehydrogenases often overexpressed in multiple solid tumors, including... 
COMPLEX | DESIGN | COREPRESSOR CTBP | RECOGNITION | APC | ZNF217 | PHARMACOLOGY & PHARMACY | REPRESSOR | IDENTIFICATION
Journal Article
Nature Communications, ISSN 2041-1723, 07/2016, Volume 7, Issue 1, p. 12148
Membrane fission is an essential cellular process by which continuous membranes split into separate parts. We have previously identified CtBP1-S/BARS (BARS) as... 
MOLECULAR-MECHANISM | CTBP/BARS | TRANSPORT | CTBP1/BARS | DOMAIN | COMPLEX | POLARIZED MDCK CELLS | MULTIDISCIPLINARY SCIENCES | PHOSPHATIDIC-ACID | ANCHORED PROTEINS | DYNAMIN
Journal Article
Biology of the Cell, ISSN 0248-4900, 01/2011, Volume 103, Issue 1, pp. 1 - 19
Background information. CtBPs [C‐terminal (of E1A) binding protein] have roles in the nucleus as transcriptional co‐repressors, and in the cytoplasm in the... 
C‐terminal (of E1A) binding protein (CtBP) protein | apoptosis | breast cancer | chemosensitivity | isoform | Chemosensitivity | C-terminal (of E1A) binding protein (CtBP) protein | Isoform | Breast cancer | Apoptosis | CELLS | REGULATES EXPRESSION | CELLULAR PHOSPHOPROTEIN | CELL BIOLOGY | NUCLEAR-LOCALIZATION | TERMINAL-BINDING-PROTEIN | TRANSCRIPTIONAL COREPRESSOR | GENE-EXPRESSION | NEGATIVE MODULATION | MOLECULAR-CLONING | P53-INDEPENDENT APOPTOSIS | Humans | Gene Expression Regulation, Neoplastic | Alcohol Oxidoreductases - metabolism | Drug Resistance, Neoplasm | DNA-Binding Proteins - genetics | Breast Neoplasms - drug therapy | Nerve Tissue Proteins - genetics | Breast Neoplasms - metabolism | Alcohol Oxidoreductases - genetics | DNA-Binding Proteins - metabolism | Nerve Tissue Proteins - metabolism | RNA Splicing | Breast Neoplasms - genetics | Cell Line, Tumor | Female | Antineoplastic Agents - pharmacology | BARS, Brefeldin A ADP-ribosylated substrate | HEK-293 cells, human embryonic kidney cells | HIPK2, homeodomain-interacting protein kinase 2 | BH3 domain, Bcl-2 homology domain 3 | DAPI, 4′,6-diamidino-2-phenylindole | siRNA, small interfering RNA | ARF, alternative reading frame | APC, adenomatous polyposis coli | RT–PCR, reverse transcription–PCR | CtBP, C-terminal (of E1A) binding protein | MTS, 3-(4,5dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium
Journal Article
Genes and Cancer, ISSN 1947-6019, 2012, Volume 3, Issue 7-8, pp. 481 - 490
The mammalian COOH-terminal binding proteins (CtBPs) CtBP1 and CtBP2 are metabolically regulated transcriptional co-repressors that are degraded upon acute... 
migration | invasion | TIAM | CtBP | transactivation | Original
Journal Article