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Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2010, Volume 184, Issue 5, pp. 2528 - 2538
Malaria results in >1,000,000 deaths per year worldwide. Although no licensed vaccine exists, much effort is currently focused on subunit vaccines that elicit... 
X-IRRADIATED SPOROZOITES | LISTERIA-MONOCYTOGENES | PROTECTIVE IMMUNITY | INTERFERON-GAMMA | LIVER STAGES | NITRIC-OXIDE SYNTHASE | IFN-GAMMA | INFLUENZA-VIRUS | IMMUNOLOGY | MALARIA HEPATIC STAGES | STERILE PROTECTION | Tumor Necrosis Factor-alpha - metabolism | Plasmodium berghei - immunology | Fas Ligand Protein - metabolism | Perforin - genetics | Dendritic Cells - immunology | Liver Diseases, Parasitic - immunology | Listeria monocytogenes - immunology | Sporozoites - immunology | Fas Ligand Protein - immunology | Signal Transduction - immunology | Malaria Vaccines - immunology | TNF-Related Apoptosis-Inducing Ligand - deficiency | Tumor Necrosis Factor-alpha - immunology | CD8-Positive T-Lymphocytes - metabolism | Female | Perforin - immunology | Interferon-gamma - genetics | Interferon-gamma - deficiency | Dendritic Cells - metabolism | Immunologic Memory - immunology | Malaria - immunology | Plasmodium yoelii - immunology | TNF-Related Apoptosis-Inducing Ligand - immunology | Liver Diseases, Parasitic - parasitology | Mice, Knockout | Malaria - prevention & control | Perforin - deficiency | Animals | Malaria Vaccines - administration & dosage | Interferon-gamma - immunology | Malaria - parasitology | Culicidae - parasitology | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | TNF-Related Apoptosis-Inducing Ligand - genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e76711
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, virus-triggered immune disease. Hypersensitivity to mosquito bite (HMB), a presentation of... 
LINKED LYMPHOPROLIFERATIVE SYNDROME | NATURAL-KILLER-CELLS | EBV INFECTION | VIRAL-DNA | MULTIDISCIPLINARY SCIENCES | VIROLOGICAL CHARACTERISTICS | NK-CELLS | T-CELLS | DEFICIENCY | LYMPHOCYTES | CHILDREN | Immunoglobulins - immunology | Granzymes - metabolism | Humans | Hypersensitivity - immunology | Intracellular Signaling Peptides and Proteins - immunology | Male | CD4-Positive T-Lymphocytes - immunology | Insect Bites and Stings - genetics | Lymphocyte Activation - immunology | Flow Cytometry | Hypersensitivity - metabolism | Immunoglobulins - blood | CD8-Positive T-Lymphocytes - metabolism | Epstein-Barr Virus Infections - genetics | Killer Cells, Natural - immunology | Female | Hypersensitivity - genetics | Granzymes - immunology | Perforin - immunology | Lymphohistiocytosis, Hemophagocytic - genetics | Intracellular Signaling Peptides and Proteins - genetics | Lymphohistiocytosis, Hemophagocytic - immunology | Insect Bites and Stings - immunology | Membrane Proteins - genetics | Epstein-Barr Virus Infections - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Herpesvirus 4, Human - immunology | Membrane Proteins - immunology | Sequence Analysis, DNA | Animals | Culicidae - immunology | Signaling Lymphocytic Activation Molecule Associated Protein | Lymphohistiocytosis, Hemophagocytic - metabolism | Insect Bites and Stings - metabolism | K562 Cells | Perforin - metabolism | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | Cytotoxicity, Immunologic - immunology | Epstein-Barr Virus Infections - metabolism | Infection | Medical research | Allergy | Mosquitoes | Killer cells | Bites and stings | Immunoglobulin E | Medicine, Experimental | Epstein-Barr virus | B cells | Health aspects | Allergic reaction | Pediatrics | Toxicity | CD8 antigen | Chronic infection | Cytotoxicity | Viruses | Oncology | Infections | Aquatic insects | Immunology | Lymphocytes | Gangrene | Perforin | Immunoglobulins | Immunological memory | Hematology | Hypersensitivity | Rheumatology | CD3 antigen | Histiocytosis | Patients | CD4 antigen | Asthma | Medicine | Convalescence | Ulcers | Histocompatibility antigen HLA | Mutation | Lymphocytosis
Journal Article
Scientific Reports, ISSN 2045-2322, 01/2016, Volume 6, Issue 1, p. 18848
Transmission-blocking vaccines (TBV) target the sexual-stages of the malaria parasite in the mosquito midgut and are widely considered to be an essential tool... 
PROTECTS MICE | OLIGOMERIZATION DOMAIN | STAGE | MULTIDISCIPLINARY SCIENCES | POXVIRUS | CANDIDATE | ANTIBODY-RESPONSES | PROTEINS | ADENOVIRUS | ADJUVANT | ANTIGEN | Immunogenicity, Vaccine | Recombinant Fusion Proteins - immunology | Malaria, Falciparum - prevention & control | Adjuvants, Immunologic - administration & dosage | Antigens, Protozoan - immunology | Germinal Center - immunology | Humans | Vaccination | Germinal Center - drug effects | Plasmodium falciparum - drug effects | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Life Cycle Stages - immunology | Pichia - metabolism | Insect Vectors - drug effects | Adjuvants, Immunologic - chemistry | Malaria Vaccines - immunology | Adenoviridae - genetics | Adjuvants, Immunologic - genetics | Antigens, Protozoan - genetics | Protozoan Proteins - administration & dosage | Adenoviridae - immunology | Recombinant Fusion Proteins - administration & dosage | Life Cycle Stages - drug effects | Gene Expression | Genetic Vectors - chemistry | Genetic Vectors - immunology | Plasmids - immunology | Culicidae - drug effects | Antibodies, Protozoan - biosynthesis | Malaria, Falciparum - parasitology | Animals | Malaria Vaccines - administration & dosage | Insect Vectors - parasitology | Malaria, Falciparum - immunology | Pichia - genetics | Plasmids - chemistry | Recombinant Fusion Proteins - genetics | Vaccines, Synthetic | Culicidae - parasitology | Mice | Mice, Inbred BALB C | Plasmodium falciparum - growth & development | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Proteins | Nanoparticles | Antigens | Disease transmission | Malaria | Immunogenicity | Midgut | Antibodies | Vectors | Vaccines | Vectors (Biology) | Antibody response
Journal Article
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 15, pp. 1898 - 1904
Highlights ► A synthetic microparticle vaccine elicits protection from malaria in mouse models. ► The vaccine is made using the layer-by-layer (LbL)... 
Allergy and Immunology | Sporozoite | Microparticle | Malaria vaccines | Peptide | MEDICINE, RESEARCH & EXPERIMENTAL | ACID) NANOPARTICLES | DENDRITIC CELLS | CIRCUMSPOROZOITE PROTEIN | T-CELL | IMMUNOLOGY | NANOPARTICLE VACCINES | IN-VITRO | B-CELL | RTS,S/AS01 MALARIA VACCINE | PHASE-3 TRIAL | CS PROTEIN | Vaccination | Molecular Sequence Data | Plasmodium falciparum - immunology | Vaccines, Synthetic - immunology | Sporozoites - immunology | Antibodies, Neutralizing - immunology | Antibodies, Protozoan - blood | Malaria Vaccines - immunology | Female | Parasites - immunology | Plasmodium falciparum - metabolism | Protozoan Proteins - chemistry | Epitopes, T-Lymphocyte - immunology | Vaccines, Synthetic - chemistry | Amino Acid Sequence | Peptides - chemistry | Antibodies, Protozoan - immunology | Malaria - immunology | Mice, Inbred C57BL | Peptides - immunology | Malaria Vaccines - chemical synthesis | Malaria - prevention & control | Immunity, Cellular - immunology | Animals | Parasites - metabolism | T-Lymphocytes - immunology | Culicidae - parasitology | Mice | Protozoan Proteins - immunology | Immune response | Peptides | Malaria | Malaria vaccine | Amino acids | Vaccines | Fluorides | Glutamate | Biopharmaceutics | Plasmodium falciparum | Analysis | Fluorescein | Genetic engineering | Public health | peptide | sporozoite | malaria vaccines | microparticle
Journal Article
Nature medicine, ISSN 1546-170X, 2016, Volume 23, Issue 2, pp. 192 - 199
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2016, Volume 45, Issue 4, pp. 889 - 902
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2018, Volume 9, p. 3006
Malaria caused by the Plasmodium family of parasites, especially P. falciparum and P. vivax, is a major health problem in many countries in the tropical and... 
pathogenesis | immunostimulatory factors | host receptors | signaling mechanisms | malaria | innate immune responses | protective immunity | PLASMODIUM-FALCIPARUM GLYCOSYLPHOSPHATIDYLINOSITOL | INTERCELLULAR-ADHESION MOLECULE-1 | TYROSINE KINASE | TOLL-LIKE RECEPTOR | IMMUNOLOGY | PLASMACYTOID DENDRITIC CELLS | PATTERN-RECOGNITION | PROTEIN-C RECEPTOR | VASCULAR ENDOTHELIAL-CELLS | PROTECTIVE-IMMUNITY | CEREBRAL MALARIA | Antigens, Protozoan - immunology | Plasmodium - pathogenicity | Humans | Protozoan Proteins - genetics | Sporozoites - immunology | Hepatocytes - parasitology | Antigens, Protozoan - metabolism | Liver - immunology | Protozoan Proteins - metabolism | Malaria Vaccines - immunology | Antigens, Protozoan - genetics | Merozoites - pathogenicity | Plasmodium - immunology | Sporozoites - pathogenicity | Merozoites - immunology | Malaria - immunology | Plasmodium - genetics | Plasmodium - metabolism | Host-Parasite Interactions - immunology | Hepatocytes - immunology | Immunity, Innate | Malaria - prevention & control | Animals | Malaria Vaccines - administration & dosage | Malaria - parasitology | Culicidae - parasitology | Liver - cytology | Disease Vectors | Liver - parasitology | Malaria - blood | Protozoan Proteins - immunology | Plasmodium falciparum | Cellular signal transduction | Immune response | Research | Malaria | Analysis
Journal Article