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cullin proteins - metabolism (21) 21
humans (21) 21
cell biology (20) 20
skp cullin f-box protein ligases - metabolism (17) 17
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cullin proteins - genetics (14) 14
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ubiquitin-protein ligases - genetics (11) 11
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ubiquitination (10) 10
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muscle proteins - metabolism (9) 9
physiological aspects (9) 9
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cullin proteins - chemistry (6) 6
dna-binding proteins - metabolism (6) 6
f-box proteins - metabolism (6) 6
gene expression (6) 6
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molecular sequence data (6) 6
muscle fibers, skeletal - ultrastructure (6) 6
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cullin proteins - ultrastructure (5) 5
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meiosis (5) 5
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Nature, ISSN 0028-0836, 03/2016, Volume 531, Issue 7596, pp. 598 - 603
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7518, pp. 388 - 393
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 5, pp. 1702 - 1707
Ltn1 is a 180-kDa E3 ubiquitin ligase that associates with ribosomes and marks certain aberrant translationally arrested nascent polypeptide chains for... 
Proteins | Datasets | Quality assurance | Messenger RNA | Surveillance | Ubiquitins | Ribosomes | Amino acids | Evolution | Electron density | RING E3 ubiquitin ligase | Conformational heterogeneity | Neurodegenerative disease | Ltn1/Listerin | Translational surveillance | SYSTEM | conformational heterogeneity | ACTIVATION | neurodegenerative disease | UBIQUITIN LIGASE | RIBOSOME RESCUE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | QUALITY-CONTROL | TRANSLATION | MESSENGER-RNA | translational surveillance | DEGRADATION | SUBUNIT | Cullin Proteins - ultrastructure | Protein Structure, Tertiary | Saccharomyces cerevisiae Proteins - ultrastructure | Ubiquitin - ultrastructure | Carrier Proteins - ultrastructure | Humans | Ubiquitin - chemistry | Ubiquitin - metabolism | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Ubiquitin-Protein Ligases - chemistry | Ubiquitin-Protein Ligases - ultrastructure | Cullin Proteins - chemistry | Particle Size | Carrier Proteins - metabolism | Microscopy, Electron - methods | Saccharomyces cerevisiae Proteins - metabolism | Cullin Proteins - metabolism | Protein Binding | Carrier Proteins - chemistry | Protein Conformation | Imaging, Three-Dimensional | Saccharomyces cerevisiae Proteins - chemistry | Ubiquitin | Physiological aspects | Dynamics of a particle | Research | Ligases | Health aspects | Biological Sciences | Listerin | Ltn1
Journal Article
Journal Article
Developmental Dynamics, ISSN 1058-8388, 03/2005, Volume 232, Issue 3, pp. 865 - 875
Journal Article
Journal Article
Science, ISSN 0036-8075, 2/2002, Volume 295, Issue 5558, pp. 1294 - 1298
Journal Article
BBA - General Subjects, ISSN 0304-4165, 03/2013, Volume 1830, Issue 3, pp. 2770 - 2778
Cachexia is a wasting condition that manifests in several types of cancer, and the main characteristic is the profound loss of muscle mass. The Yoshida AH-130... 
Cancer cachexia | ANT1 | SERCA | Muscle wasting | Sarcoplasmic reticulum | Mitochondri | APOPTOSIS | TUMOR-BEARING RATS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-DEATH | HEAT-PRODUCTION | BIOPHYSICS | DNA FRAGMENTATION | CA2 | SKELETAL-MUSCLE FIBERS | ENDOPLASMIC-RETICULUM | DYSFUNCTION | VI MUSCULAR-DYSTROPHIES | Cachexia - complications | Adenosine Triphosphate - deficiency | Rats, Wistar | SKP Cullin F-Box Protein Ligases - genetics | Sarcoma, Yoshida - complications | Apoptosis - genetics | Male | Muscle, Skeletal - metabolism | Mitochondria - ultrastructure | Tripartite Motif Proteins | Cell Nucleus - metabolism | Proteolysis | Muscle Proteins - metabolism | Sarcoplasmic Reticulum - ultrastructure | Sarcoplasmic Reticulum - metabolism | Energy Metabolism - genetics | Muscular Atrophy - complications | Cachexia - metabolism | Adenine Nucleotide Translocator 1 - genetics | Gene Expression | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Muscular Atrophy - metabolism | Muscular Atrophy - pathology | Ubiquitin-Protein Ligases - metabolism | Rats | Adenine Nucleotide Translocator 1 - metabolism | Mitochondria - metabolism | SKP Cullin F-Box Protein Ligases - metabolism | Cell Nucleus - ultrastructure | Muscle Proteins - genetics | Animals | Cachexia - pathology | Muscle, Skeletal - pathology | Sarcoma, Yoshida - pathology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - genetics | Ubiquitin-Protein Ligases - genetics | Sarcoma, Yoshida - metabolism | Cachexia | Cancer
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 6/2019, Volume 76, Issue 11, pp. 2217 - 2229
As the female gamete, meiotic oocytes provide not only half of the genome but also almost all stores for fertilization and early embryonic development. Because... 
Life Sciences | Biomedicine, general | Biochemistry, general | Chromosome condensation | SLBP | Ubiquitination | Life Sciences, general | Cell cycle | F-box family | Cell Biology | BIOCHEMISTRY & MOLECULAR BIOLOGY | F-BOX PROTEINS | SPINDLE | SELF-ORGANIZATION | IDENTIFICATION | SCF UBIQUITIN-LIGASE | CELL BIOLOGY | MOUSE OOCYTES | CONDENSATION | DEGRADATION | CHROMATIN MODIFICATIONS | MEIOTIC CELL-CYCLE | Oocytes - ultrastructure | RNA, Small Interfering - genetics | mRNA Cleavage and Polyadenylation Factors - metabolism | Tubulin - genetics | F-Box Proteins - antagonists & inhibitors | Tubulin - metabolism | Gene Expression Regulation, Developmental | Female | Nuclear Proteins - genetics | mRNA Cleavage and Polyadenylation Factors - genetics | Chromosome Segregation | Signal Transduction | F-Box Proteins - metabolism | Oocytes - metabolism | Nuclear Proteins - metabolism | Meiosis | Mice, Inbred ICR | Animals | Histones - genetics | Chromosomes, Mammalian - ultrastructure | Mice | Histones - metabolism | Primary Cell Culture | Chromosomes, Mammalian - metabolism | F-Box Proteins - genetics | RNA, Small Interfering - metabolism | Ubiquitin | Embryonic development | RNA | Ligases | Analysis | Genomics | Chromosomes | Mass spectrometry | Protein binding | Immunoprecipitation | Transcription | Fertilization | Stem-loop-binding protein | Genomes | Substrates | Oocytes | Cullin | Proteins | Embryonic growth stage | Spectrometry | Embryogenesis | Depletion | Metaphase | Histone H3
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 06/2002, Volume 13, Issue 6, pp. 1916 - 1928
The SCF (for SKP1, Cullin/CDC53, F-box protein) ubiquitin ligase targets a number of cell cycle regulators, transcription factors, and other proteins for... 
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 04/2008, Volume 22, Issue 7, pp. 866 - 871
Journal Article
Critical Care Medicine, ISSN 0090-3493, 07/2011, Volume 39, Issue 7, pp. 1749 - 1759
BACKGROUND:Mechanical ventilation is a life-saving intervention used to provide adequate pulmonary ventilation in patients suffering from respiratory failure.... 
atrophy | antioxidant | redox signaling | respiratory muscles | oxidative stress | weaning |