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European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 11/2017, Volume 109, pp. 21 - 30
The lipophilic phytocannabinoids cannabidiol (CBD) and Δ -tetrahydrocannabinol (THC) show therapeutic efficacy in various medical conditions. Both molecules... 
Cannabinoids | Oral bioavailability | Piperine | SNEDDS | First pass effect | RESVERATROL | CURCUMIN | P-GLYCOPROTEIN | UDP-GLUCURONOSYLTRANSFERASE | IN-VITRO | LIPID-BASED FORMULATIONS | METABOLISM | PHARMACOKINETICS | ENZYMES | PHARMACOLOGY & PHARMACY | Polyunsaturated Alkamides - chemistry | Emulsions | Stilbenes - administration & dosage | Cannabidiol - administration & dosage | Excipients - pharmacokinetics | Nanoparticles - chemistry | Rats, Wistar | Alkaloids - pharmacokinetics | Curcumin - chemistry | Biological Availability | Male | Stilbenes - chemistry | Benzodioxoles - administration & dosage | Curcumin - administration & dosage | Drug Delivery Systems | Lipids - chemistry | Excipients - chemistry | Benzodioxoles - pharmacokinetics | Piperidines - pharmacokinetics | Benzodioxoles - chemistry | Cannabidiol - pharmacokinetics | Cannabidiol - chemistry | Piperidines - administration & dosage | Piperidines - chemistry | Gastrointestinal Absorption | Administration, Oral | Curcumin - pharmacokinetics | Lipids - administration & dosage | Dronabinol - pharmacokinetics | Excipients - administration & dosage | Polyunsaturated Alkamides - administration & dosage | Animals | Lipids - pharmacokinetics | Stilbenes - pharmacokinetics | Alkaloids - administration & dosage | Nanoparticles - administration & dosage | Polyunsaturated Alkamides - pharmacokinetics | Dronabinol - administration & dosage | Dronabinol - chemistry | Alkaloids - chemistry | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e14015 - e14015
Background: Dietary supplements have been extensively studied for their beneficial effects on cognition and AD neuropathology. The current study examines the... 
CURCUMIN | MEMORY DEFICITS | AMYLOID-BETA | PIPERINE | BIOLOGY | RATS | TEA POLYPHENOL (-)-EPIGALLOCATECHIN-3-GALLATE | RECOGNITION MEMORY | MICE | TRANSGENIC MODEL | TAU-PATHOLOGY | Memory - drug effects | Thioctic Acid - administration & dosage | Humans | Cerebral Cortex - pathology | Catechin - administration & dosage | Immunoblotting | Hippocampus - drug effects | Benzodioxoles - administration & dosage | Curcumin - administration & dosage | Folic Acid - administration & dosage | Vitamin B Complex - administration & dosage | Cerebral Cortex - physiopathology | Amyloid beta-Protein Precursor - metabolism | Cognition - physiology | Cerebral Cortex - drug effects | Acetylcysteine - administration & dosage | Alzheimer Disease - physiopathology | Piperidines - administration & dosage | Brain - physiopathology | Mice, Inbred C57BL | Alzheimer Disease - drug therapy | Ascorbic Acid - administration & dosage | Mice, Transgenic | Hippocampus - pathology | Cognition - drug effects | Maze Learning - drug effects | Mice, Inbred Strains | Brain - drug effects | Polyunsaturated Alkamides - administration & dosage | Amyloid beta-Protein Precursor - genetics | Animals | Brain - pathology | Alkaloids - administration & dosage | Catechin - analogs & derivatives | Mice | Alzheimer Disease - genetics | Dietary Supplements | Hippocampus - physiopathology | Vitamins - administration & dosage | Oligomers | Advertising executives | Catechin | Analysis | Dietary supplements | Acetylcysteine | Models | Genetic engineering | Research | Alzheimer's disease | Folic acid | Lipoic acid | Neurosciences | Memory | Cognitive ability | Neurobiology | Medical services | Cytotoxicity | Cognition | Antioxidants | Proteins | Learning | Ischemia | Transgenic animals | Rodents | Curcumin | Behavior | Neurological disorders | Food | Neurodegenerative diseases | Cortex | Ingredients | Transgenic mice | Studies | Pathology | Epigallocatechin gallate | Diet | β-Amyloid | Alzheimers disease | Hippocampus | Dementia | Index Medicus
Journal Article
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 08/2010, Volume 9, Issue 8, pp. 2255 - 2264
Journal Article
Cancer Prevention Research, ISSN 1940-6207, 02/2013, Volume 6, Issue 2, pp. 119 - 128
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 11, pp. e111559 - e111559
Despite the widespread use of curcumin for centuries in Eastern medicine as an anti-inflammatory agent, its molecular actions and therapeutic viability have... 
RHEUMATOID-ARTHRITIS | CELLS | IN-VITRO | ACTIVATION | CLINICAL-TRIAL | GENE | MULTIDISCIPLINARY SCIENCES | LIPOPOLYSACCHARIDE | RECEPTOR | EXPRESSION | BIOAVAILABILITY | Cell Line | Administration, Oral | Anti-Inflammatory Agents - pharmacology | Emulsions - chemistry | Humans | Curcumin - pharmacology | NF-kappa B - immunology | Macrophages - cytology | Curcumin - administration & dosage | Lipopolysaccharides - immunology | Drug Carriers - chemistry | Cell Movement - drug effects | Animals | Signal Transduction - drug effects | Anti-Inflammatory Agents - administration & dosage | Macrophages - drug effects | Mice | Mice, Inbred BALB C | Macrophages - immunology | Phosphorylation | Leukocyte migration | Cardiovascular disease | Lymphocytes T | Macrophages | Inflammatory diseases | Lipopolysaccharides | Recruitment | Proteins | Reporter gene | Immunology | Metabolites | Rodents | Toll-like receptors | Curcumin | Inhibition | Drug dosages | Peritonitis | Internal medicine | Secretion | Oral administration | Rheumatology | Transgenic mice | Data processing | Inflammation | TLR4 protein | Bioavailability | Metabolism | Gene expression | Asthma | Medicine | Studies | Inflammatory bowel disease | Signaling | Immunosuppression | Monocytes | Molecular modelling | Lymphocytes B | Rheumatoid arthritis | Pharmacy | Cell lines | In vivo methods and tests | Diabetes | Viability | Cell migration | Monocyte chemoattractant protein 1 | Cancer | Index Medicus
Journal Article
Clinical Nutrition, ISSN 0261-5614, 2015, Volume 34, Issue 6, pp. 1101 - 1108
Summary Background Oxidative stress and inflammation have been proposed as emerging components of metabolic syndrome (MetS). Curcuminoids are natural... 
Gastroenterology and Hepatology | Turmeric | Cardiovascular disease | Antioxidant | Curcuma longa | Randomized controlled trial | C-REACTIVE PROTEIN | OXIDATIVE STRESS | MYOCARDIAL-INFARCTION | RISK | ENDOTHELIAL FUNCTION | IN-VITRO | NUTRITION & DIETETICS | INFLAMMATION | DOUBLE-BLIND | CLINICAL-PRACTICE | ASSOCIATION | Blood Pressure | Meta-Analysis as Topic | Alkaloids - pharmacokinetics | Humans | Middle Aged | Superoxide Dismutase - blood | Biological Availability | Male | Benzodioxoles - administration & dosage | Curcumin - administration & dosage | Metabolic Syndrome - drug therapy | C-Reactive Protein - metabolism | Benzodioxoles - pharmacokinetics | Inflammation - drug therapy | Malondialdehyde - blood | Adult | Anti-Inflammatory Agents - administration & dosage | Anti-Inflammatory Agents - pharmacokinetics | Female | Piperidines - pharmacokinetics | Databases, Factual | Body Mass Index | Piperidines - administration & dosage | Double-Blind Method | Curcumin - pharmacokinetics | Polyunsaturated Alkamides - administration & dosage | Antioxidants - administration & dosage | Alkaloids - administration & dosage | Polyunsaturated Alkamides - pharmacokinetics | Oxidative Stress - drug effects | Antioxidants - pharmacokinetics | Dietary Supplements | Antioxidants | Polyphenols | Anti-inflammatory drugs | Analysis | Index Medicus
Journal Article
08/2012
Purpose: To develop a proniosomal carrier system of curcumin for transdermal delivery. Methods: Proniosomes of curcumin were prepared by encapsulation of the... 
Proniosomes | Drug stability | Transdermal drug delivery | In vitro release | Curcumin
Web Resource
Phytotherapy Research, ISSN 0951-418X, 12/2018, Volume 32, Issue 12, pp. 2408 - 2416
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 11/2010, Volume 99, Issue 11, pp. 4630 - 4641
The aim of this study was to evaluate the effect of curcumin (CUR) in oral bioavailability and therapeutic efficacy of paclitaxel (PTX) administered in... 
oil-in-water nanoemulsion | oral bioavailability | paclitaxel/curcumin co-therapy | therapeutic efficacy | ovarian adenocarcinoma | oil‐in‐water nanoemulsion | paclitaxel/curcumin co‐therapy | Therapeutic efficacy | Oral bioavailability | Paclitaxel/curcumin co-therapy | Ovarian adenocarcinoma | Oil-in-water nanoemulsion | CHEMISTRY, MEDICINAL | TURMERIC POWDER | DRUG-DELIVERY | MULTIFUNCTIONAL NANOCARRIERS | FACTOR-KAPPA-B | TUMOR-CELLS | CANCER | CHEMISTRY, MULTIDISCIPLINARY | P-GLYCOPROTEIN ABCB1 | RESISTANCE PROTEIN-1 ABCC1 | DEOXYCHOLIC-ACID | PHARMACOLOGY & PHARMACY | MULTIDRUG-RESISTANCE | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Paclitaxel - pharmacology | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Biological Availability | Paclitaxel - pharmacokinetics | Curcumin - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Enzyme Inhibitors - administration & dosage | Antineoplastic Agents, Phytogenic - administration & dosage | Female | Antineoplastic Agents, Phytogenic - therapeutic use | Paclitaxel - administration & dosage | Antineoplastic Agents, Phytogenic - pharmacokinetics | Ovarian Neoplasms - drug therapy | Emulsions - chemistry | Curcumin - pharmacology | Enzyme Inhibitors - pharmacology | Adenocarcinoma - drug therapy | Paclitaxel - therapeutic use | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cytochrome P-450 CYP3A - metabolism | Mice | Antineoplastic Agents, Phytogenic - pharmacology | Index Medicus
Journal Article