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BBA - Molecular Basis of Disease, ISSN 0925-4439, 02/2014, Volume 1842, Issue 2, pp. 208 - 219
Journal Article
PLANTA, ISSN 0032-0935, 08/2019, Volume 250, Issue 2, pp. 589 - 601
Journal Article
Progress in molecular biology and translational science, ISSN 1877-1173, 2017, Volume 146, pp. 259 - 302
Mitochondrial and bioenergetic function change with advancing age and may drive aging phenotypes. Mitochondrial and bioenergetic changes are also documented in... 
Aging | Alzheimer’s disease | bioenergetics cybrids | mitochondria
Journal Article
TRENDS IN NEUROSCIENCES, ISSN 0166-2236, 11/2019, Volume 42, Issue 11, pp. 759 - 762
Multiple features distinguish the mitochondria of Alzheimer's disease (AD) patients from those of unaffected individuals. The causes and consequences of these... 
NEUROSCIENCES | DISEASE | CYBRIDS | Medicine, Experimental | Medical research | Medical colleges | Neurosciences | Alzheimer's disease
Journal Article
Human Mutation, ISSN 1059-7794, 01/2018, Volume 39, Issue 1, p. 92
Respiratory complex III (CIII) is the first enzymatic bottleneck of the mitochondrial respiratory chain both in its native dimeric form and in supercomplexes.... 
Cytochrome | Mitochondria | Ubiquinol | Cytochrome b | Cybrids | Mitochondrial DNA | Oxidation | Superoxide | Mutation | Electron transport | Amino acid substitution
Journal Article
BIOMOLECULES, ISSN 2218-273X, 09/2019, Volume 9, Issue 9, p. 499
In the present work, a pilot creation of four cybrid cultures with high heteroplasmy level was performed using mitochondrial genome mutations m.12315G>A and... 
mutation | cybrid model | gene | mtDNA | therapy | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | mitochondrial genome | cytoplasmatic hybrids | cybrids
Journal Article
Journal Article
Journal Article
Trends in Ecology & Evolution, ISSN 0169-5347, 2004, Volume 19, Issue 12, pp. 645 - 653
Without mitochondria we would be in big trouble, and there would be a global biological energy crisis if it were not for chloroplasts. Fortunately, genomic... 
HUMAN MTDNA | DROSOPHILA-MELANOGASTER | WOLBACHIA-PIPIENTIS | NUCLEAR GENOMES | MITOCHONDRIAL GENE CONTENT | MARINE COPEPOD | CYTOCHROME-C-OXIDASE | EVOLUTIONARY BIOLOGY | GENETICS & HEREDITY | ECOLOGY | XENOMITOCHONDRIAL CYBRIDS | ORGANELLE GENOMES | DELETERIOUS MUTATIONS
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2010, Volume 113, Issue 3, pp. 674 - 682
J. Neurochem. (2010) 113, 674–682. Parkinson’s disease (PD) is associated with perturbed mitochondrial function. Studies of cytoplasmic hybrid (cybrid) cell... 
respiration | mitochondria | Parkinson’s disease | cybrids
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 02/2019, Volume 28, Issue 3, pp. 422 - 433
Abstract Leber's hereditary optic neuropathy (LHON) is a classical mitochondrial disease caused by mutations in the mitochondrial DNA encoding complex I... 
COMPLEX I | OXIDATIVE STRESS | DEFECTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENERGETIC DEPRESSION | GENETICS & HEREDITY | POTENTIAL THERAPEUTIC TARGET | DEATH | AUTOPHAGY | MUTATIONS | CYBRIDS | IMPAIRMENT
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2015, Volume 467, Issue 4, pp. 1097 - 1102
We searched for mtDNA harboring somatic mutations in mouse B82 cells, and found an A2748G mutation orthologous to the A3302G mutation in gene reported in a... 
Mouse mtDNA | Somatic mutations | Orthologous to MELAS | tRNALeu(UUR) gene | ES cybrids | tRNA | gene
Journal Article