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Biochemical Pharmacology, ISSN 0006-2952, 03/2012, Volume 83, Issue 6, pp. 705 - 714
CREB-mediated transcription can be initiated by membrane receptor stimulation and subsequent activation of intracellular pathways to the cell nucleus, and has... 
CREB phosphorylation | H3 antagonist | HSD1 inhibitor | Alzheimer's disease | α7 nAChR agonist | ACTIVATION | LONG-TERM-MEMORY | AMYLOID PRECURSOR PROTEIN | ERK MAP KINASE | alpha 7 nAChR agonist | DORSAL HIPPOCAMPUS | NICOTINIC ACETYLCHOLINE-RECEPTOR | IMPAIRED PHOSPHORYLATION | PHARMACOLOGY & PHARMACY | APLYSIA SENSORY NEURONS | HISTAMINE H-3 RECEPTOR | SIGNAL-REGULATED KINASE | Memory - drug effects | Brain-Derived Neurotrophic Factor - genetics | Humans | Rats, Inbred F344 | Hippocampus - drug effects | Cerebral Cortex - metabolism | Cerebral Cortex - physiopathology | Cognition - physiology | Brain-Derived Neurotrophic Factor - metabolism | Neurons - metabolism | Cerebral Cortex - drug effects | Histamine H3 Antagonists - therapeutic use | Phosphorylation - drug effects | Receptors, Histamine H3 - metabolism | Nicotinic Agonists - pharmacology | Biomarkers - metabolism | Receptors, Nicotinic - metabolism | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Alzheimer Disease - drug therapy | Rats | Mice, Transgenic | Cognition - drug effects | Nicotinic Agonists - therapeutic use | 11-beta-Hydroxysteroid Dehydrogenase Type 1 - antagonists & inhibitors | Enzyme Inhibitors - therapeutic use | Histamine H3 Antagonists - pharmacology | Hippocampus - metabolism | 11-beta-Hydroxysteroid Dehydrogenase Type 1 - metabolism | Animals | Signal Transduction - drug effects | Models, Biological | Alzheimer Disease - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Signal Transduction - physiology | Mice | Hippocampus - physiopathology | Memory - physiology | alpha7 Nicotinic Acetylcholine Receptor | Phosphorylation | Neurodegenerative diseases | Transcription | Memory | Cognitive ability | Cortex | Antagonists | Regulatory sequences | Cyclic AMP response element-binding protein | Learning | Brain-derived neurotrophic factor | Plasticity (synaptic) | DNA | Transcription activation | Hippocampus | Index Medicus
Journal Article
Anti-Cancer Drugs, ISSN 0959-4973, 04/2019, Volume 30, Issue 4, pp. 363 - 373
Bromodomains are epigenetic readers of acetyl-lysine involved in chromatin remodeling and transcriptional regulations. Over the past few years, extensive... 
cancer therapy | computational analyses | cyclic AMP response element-binding protein | BROMODOMAIN INHIBITORS | MOLECULAR-DYNAMICS | DESIGN | RECOGNITION | MOTIONS | CANCER | POTENT | ONCOLOGY | PHARMACOLOGY & PHARMACY | OPTIMIZATION | Epigenetic inheritance | Care and treatment | Usage | Analysis | Research | Binding proteins | Cancer
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2005, Volume 280, Issue 49, pp. 40398 - 40401
Journal Article
by Yu, QH and Li, W and Jin, R and Yu, SY and Xie, DW and Zheng, XC and Zhong, W and Cheng, X and Hu, SB and Li, M and Zheng, QC and Li, GH and Song, ZF
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, ISSN 1079-5642, 03/2019, Volume 39, Issue 3, pp. E91 - E105
Objective Vascular smooth muscle cells (VSMCs) phenotype modulation is critical for the resolution of vascular injury. Genetic and pharmacological inhibition... 
cell proliferation | PHOSPHATIDYLINOSITOL 3-KINASE | HIPPO PATHWAY | carotid arteries | PROLIFERATION | GROWTH-FACTOR-BB | muscle cells | bone marrow | IN-VITRO | LYSOPHOSPHATIDIC ACID | GENE | cyclic AMP response element binding protein | P110-GAMMA | PERIPHERAL VASCULAR DISEASE | PI3K-GAMMA | HEMATOLOGY | EXPRESSION
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 03/2016, Volume 136, Issue 5, pp. 918 - 930
Neuroglial interactions were examined using coculture models of human neuroprogenitor cell‐derived neurons and microglia isolated from human fetal brain. A... 
CREB | neuroinflammation | signal transduction | Alzheimer's disease | microglia | human neuroprogenitor cells | CELLS | MICROGLIAL ACTIVATION | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEDIATED DOWN-REGULATION | TRANSCRIPTION | NECROSIS-FACTOR-ALPHA | DIFFERENTIAL REGULATION | NEUROSCIENCES | HIPPOCAMPAL NEUROGENESIS | TRANSGENIC MICE | BCL-2 PROMOTER | Microglia - cytology | Cell Survival - drug effects | Cytokines - metabolism | Microglia - drug effects | Apoptosis - drug effects | Down-Regulation | Cells, Cultured | Neurons - cytology | Animals | Cell Differentiation - drug effects | Cyclic AMP Response Element-Binding Protein - metabolism | Female | Signal Transduction - physiology | Brain-Derived Neurotrophic Factor - metabolism | Mice | Apoptosis - physiology | Cell Differentiation - physiology | Analysis | Protein binding | Neurochemistry | Proteins | Apoptosis | Brain | Cell culture | Regulations | Transcription factors | Membranes | Phosphorylation | Central nervous system | Homeostasis | Nervous system | Activation | Glial cells | Neuronal-glial interactions | Interleukin 6 | Interleukin 1 | Minocycline | Tumor necrosis factor-TNF | Conditioning | Neurotoxins | Proximity | Cell survival | AMP | Cytokines | Neurons | Fetuses | Markers | Cyclic AMP | Cultures | Inflammation | Cyclic AMP response element-binding protein | Microglia | Brain-derived neurotrophic factor | Overexpression | Tumor necrosis factor | Synapsin | CXCL10 protein | Toxins | Index Medicus
Journal Article
Journal Article
Blood, ISSN 0006-4971, 01/2012, Volume 119, Issue 1, pp. 308 - 319
Increased endothelial permeability contributes to the morbidity and mortality associated with chronic inflammatory diseases, including acute lung injury.... 
PULMONARY ENDOTHELIUM | BARRIER DYSFUNCTION | RHOA ACTIVATION | IN-VIVO | P190 RHOGAP | LUNG INJURY | HEMATOLOGY | THROMBIN-INDUCED INCREASE | NF-KAPPA-B | MICROVASCULAR PERMEABILITY | VASCULAR LEAKAGE | Endothelium, Vascular - cytology | Capillary Permeability - physiology | RNA, Small Interfering - genetics | Luciferases - metabolism | Humans | Capillary Permeability - drug effects | Endothelium, Vascular - drug effects | Hemostatics - pharmacology | Promoter Regions, Genetic - genetics | Histamine - metabolism | Pulmonary Artery - metabolism | Flow Cytometry | Thrombin - pharmacology | Chromatin Immunoprecipitation | Guanine Nucleotide Exchange Factors - metabolism | Electrophoretic Mobility Shift Assay | Real-Time Polymerase Chain Reaction | Repressor Proteins - metabolism | Guanine Nucleotide Exchange Factors - genetics | Signal Transduction | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Gene Expression Regulation | Microvessels - drug effects | Repressor Proteins - genetics | Pulmonary Artery - drug effects | Blotting, Western | Pulmonary Artery - cytology | Cyclic AMP Response Element-Binding Protein - genetics | Animals | Endothelium, Vascular - metabolism | Cyclic AMP Response Element-Binding Protein - antagonists & inhibitors | Cyclic AMP Response Element-Binding Protein - metabolism | Lipopolysaccharides - pharmacology | Mice | Index Medicus | Abridged Index Medicus | Vascular Biology
Journal Article
Neuroscience, ISSN 0306-4522, 2011, Volume 200, pp. 13 - 18
Journal Article
Neuroscience, ISSN 0306-4522, 2009, Volume 159, Issue 4, pp. 1208 - 1215
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2012, Volume 287, Issue 45, pp. 38041 - 38049
Journal Article