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Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 09/2012, Volume 109, Issue 41, pp. 16624 - 16629
.... nNOS is phosphorylated by cAMP-dependent protein kinase (PKA) at serine(S) 1412. Electrical stimulation of the penile innervation increases S1412 phosphorylation that is blocked by PKA inhibitors but not by PI3-kinase/Akt inhibitors... 
Alternative splicing | Phosphorylation | Calcium | Penile erection | Electrical stimulation | Antibodies | Oxides | Smooth muscle | Physiology | Physiological regulation | Phosphoantibody | Smooth muscle relaxation | Gasotransmitter | Cyclic GMP | Endothelial NOS | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immunohistochemistry | Penis - physiology | Electric Stimulation | Male | Penis - innervation | Penile Erection - drug effects | Nitric Oxide Synthase Type I - antagonists & inhibitors | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Cyclic AMP - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Colforsin - pharmacology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Rats | Rats, Sprague-Dawley | Serine - metabolism | Blotting, Western | Mice, Knockout | Animals | Penis - metabolism | Nitric Oxide Synthase Type I - metabolism | Mice | Nitric Oxide Synthase Type I - genetics | Penile Erection - physiology | Penis | Nitric oxide | Physiological aspects | Cyclic adenylic acid | Research | Health aspects | Index Medicus | smooth muscle relaxation | gasotransmitter | Biological Sciences | endothelial NOS | phosphoantibody | cyclic GMP
Journal Article
Neuropsychopharmacology (New York, N.Y.), ISSN 1740-634X, 08/2011, Volume 37, Issue 2, pp. 338 - 349
...) and NMDAR NR1 subunits associate in the postsynaptic structures of PAG neurons. Morphine disrupts this complex by protein kinase-C (PKC... 
mu-opioid receptor | N-methyl-D-aspartate receptor | pain | receptor association | periaqueductal gray | analgesia | Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Phosphorylation - physiology | Injections, Intraventricular | Periaqueductal Gray - drug effects | Receptors, N-Methyl-D-Aspartate - metabolism | Drug Tolerance - physiology | Male | N-Methylaspartate - pharmacology | G-Protein-Coupled Receptor Kinase 2 - antagonists & inhibitors | Receptor Aggregation - drug effects | Neurons - metabolism | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Morphine - antagonists & inhibitors | CHO Cells | Cricetinae | Protein Kinase C - physiology | Morphine - pharmacology | Pain - prevention & control | G-Protein-Coupled Receptor Kinase 2 - physiology | Receptors, Opioid, mu - metabolism | Protein Kinase C - antagonists & inhibitors | Mice, Inbred ICR | Periaqueductal Gray - metabolism | Cyclic AMP-Dependent Protein Kinases - physiology | Receptor Aggregation - physiology | Animals | Pain - physiopathology | Mice | Morphine - administration & dosage | Index Medicus | Life Sciences | Pharmacology | Pharmaceutical sciences | signal transduction | analgesics | mouse | N-methyl--aspartate receptor | NMDA | Original | glutamate | opioids
Journal Article
Cellular signalling, ISSN 0898-6568, 12/2012, Volume 24, Issue 12, pp. 2396 - 2406
...) dependent protein kinase (PKA) plays a role in this process. We found that hypoxia increased PKA activity and induced mRNA and protein expression of PKA catalytic subunit α (PKACA... 
Hypoxia inducible factor | Lung cancer | Migration | Invasion | PKA | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Lung Neoplasms - metabolism | Epithelial-Mesenchymal Transition - drug effects | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Lung Neoplasms - pathology | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - genetics | Cell Hypoxia | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | Isoquinolines - pharmacology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - antagonists & inhibitors | RNA Interference | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Transforming Growth Factor beta1 - pharmacology | Cyclic AMP-Dependent Protein Kinases - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Colforsin - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | 8-Bromo Cyclic Adenosine Monophosphate - pharmacology | Basic Helix-Loop-Helix Transcription Factors - antagonists & inhibitors | Sulfonamides - pharmacology | Up-Regulation - drug effects | Cell Movement - drug effects | Animals | Cell Line, Tumor | Mice | RNA, Small Interfering - metabolism | Chemical inhibitors | Messenger RNA | Gene expression | Protein kinases | Cancer cells | Index Medicus | Proteins | Inhibitors | Lungs | Hypoxia | Activation | Kinases | Cancer
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2006, Volume 281, Issue 36, pp. 26159 - 26169
Journal Article
Diabetes (New York, N.Y.), ISSN 0012-1797, 2006, Volume 55, Issue 8, pp. 2220 - 2230
.... We observed that 10 mmol/1 glucose-induced CREB phosphorylation was totally inhibited by the protein kinase A (PKA) inhibitor H89 (2 mu mol/1) and reduced by 50... 
Protein kinase A | DMEM | Glucagon-like peptide-1 | CREB | GLP-1 | cAMP-responsive element-binding protein | PKA | Extracellular signal-regulated kinase | Dulbecco's modified Eagle's medium | ERK | siRNA, small interfering RNA | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | RNA, Small Interfering - genetics | Phosphorylation | Rats, Wistar | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | RNA, Messenger - analysis | Male | CREB-Binding Protein - metabolism | Isoquinolines - pharmacology | Transfection | Mitogen-Activated Protein Kinase 1 - genetics | Proto-Oncogene Proteins c-bcl-2 - analysis | Flavonoids - pharmacology | Islets of Langerhans - ultrastructure | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Cell Line | Microscopy, Electron, Transmission | Gene Expression | Islets of Langerhans - physiology | Mitogen-Activated Protein Kinase 1 - physiology | Mitogen-Activated Protein Kinase 3 - genetics | Cell Survival | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Rats | Glucose - pharmacology | Sulfonamides - pharmacology | Genes, bcl-2 - genetics | Mitogen-Activated Protein Kinase 3 - physiology | Cyclic AMP-Dependent Protein Kinases - physiology | Animals | CREB-Binding Protein - analysis | Protein Kinase Inhibitors - pharmacology | Apoptosis | Index Medicus | Abridged Index Medicus | Isoquinolines | Glucose | Life Sciences | Endocrinology and metabolism | Cyclic AMP-Dependent Protein Kinases | CREB-Binding Protein | Genes, bcl-2 | Human health and pathology | Protein Kinase Inhibitors | Flavonoids | Sulfonamides | RNA, Small Interfering | Islets of Langerhans | Proto-Oncogene Proteins c-bcl-2 | Mitogen-Activated Protein Kinase 1 | RNA, Messenger | Mitogen-Activated Protein Kinase 3
Journal Article
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 10/2007, Volume 179, Issue 8, pp. 5159 - 5168
Journal Article