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Organic Letters, ISSN 1523-7060, 08/2018, Volume 20, Issue 16, pp. 4791 - 4795
Overexpression of the Pseudomonas virulence factor (pvf) biosynthetic operon led to the identification of a family of pyrazine N-oxides (PNOs), including a... 
BACTERIA | BIOSYNTHESIS | ESCHERICHIA-COLI | SYRINGAE | CHEMISTRY, ORGANIC | SYNTHETASE | OXYGENASE | VIRULENCE | PYRAZINES | PEPTIDE | BIOFILM FORMATION | Genome, Bacterial | Virulence Factors - genetics | Operon | Cyclic N-Oxides - metabolism | Biosynthetic Pathways | Pyrazines - metabolism | Pseudomonas - genetics | Pseudomonas - metabolism | Peptide Synthases - metabolism
Journal Article
Journal Article
Science, ISSN 0036-8075, 01/2017, Volume 356, Issue 6342, pp. 1084 - 1087
A recent phase 1 trial of the fatty acid amide hydrolase (FAAH) inhibitor BIA 10-2474 led to the death of one volunteer and produced mild-to-severe... 
MOLECULAR CHARACTERIZATION | ENZYME | PAIN | ACID AMIDE HYDROLASE-1 | CLINICAL-TRIAL | MULTIDISCIPLINARY SCIENCES | ANANDAMIDE | RECEPTOR | BLOCKADE | ESTERASE | PF-04457845 | Anti-Anxiety Agents - metabolism | Analgesics - pharmacology | Pyridines - chemistry | Humans | Analgesics - metabolism | Pyridazines - pharmacology | Protein Interaction Maps | Pyridines - adverse effects | Cyclic N-Oxides - adverse effects | Cyclic N-Oxides - pharmacology | Urea - analogs & derivatives | Cyclic N-Oxides - metabolism | Anti-Anxiety Agents - adverse effects | Anti-Anxiety Agents - chemistry | Neurons - metabolism | Neurons - drug effects | Pyridazines - therapeutic use | Analgesics - adverse effects | Anti-Anxiety Agents - pharmacology | Amidohydrolases - antagonists & inhibitors | Cross Reactions | Cyclic N-Oxides - chemistry | Urea - therapeutic use | Pyridines - metabolism | Analgesics - chemistry | Cell Line, Tumor | Pyridines - pharmacology | Clinical Trials, Phase I as Topic | Urea - pharmacology | Amino acid sequence | Methods | Fatty-acid amide hydrolase | Brain | Profiling | Hydrolase | Neurons | Therapeutic applications | Nervous system | Tissue analysis | Metabolism | Lipase | Tissues | Fatty acids | Proteins | Neurotoxicity | Cannabinoids | Pain | Inhibitors | Brain damage | Anxiety | Lipid metabolism | Brain injury | Index Medicus | Drugs | Networks | Proteomics | Amides
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 2012, Volume 52, Issue 2, pp. 527 - 536
Journal Article
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 04/2017, Volume 56, Issue 4, pp. 532 - 538
Journal Article
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 01/2014, Volume 20, Issue 2, pp. 281 - 294
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e38369
Surfactant proteins (SPs) are important lipoprotein complex components, expressed in alveolar epithelial cells type II (AECII), and playing an essential role... 
SP-A GENE | LUNG | MESSENGER-RNA | PHOSPHODIESTERASE-4 INHIBITOR | MULTIDISCIPLINARY SCIENCES | SP-A2 GENES | PROINFLAMMATORY CYTOKINES | MESENCHYMAL TRANSITION | TRANSCRIPTION FACTOR-I | PULMONARY-FIBROSIS | RESPIRATORY-DISTRESS-SYNDROME | Pulmonary Surfactant-Associated Proteins - genetics | Pulmonary Surfactant-Associated Proteins - metabolism | Epithelial Cells - metabolism | Intracellular Space - drug effects | Phosphoric Diester Hydrolases - metabolism | Epithelial Cells - drug effects | Humans | Middle Aged | RNA, Messenger - genetics | Phosphodiesterase Inhibitors - pharmacology | Male | RNA, Messenger - metabolism | Indomethacin - pharmacology | Dinoprostone - metabolism | Gene Expression Regulation - drug effects | Isoenzymes - metabolism | Aminopyridines - pharmacology | Intracellular Space - metabolism | Pulmonary Alveoli - cytology | Female | Benzamides - pharmacology | Cyclic AMP - metabolism | Cyclopropanes - pharmacology | Proteins | Surface active agents | RNA | Analysis | Prostaglandins E | Cyclic adenylic acid | Adenylic acid | Thoracic surgery | Epithelial cells | Lung cancer | Prostaglandin E2 | Lipids | mRNA | Prostaglandin endoperoxide synthase | Surgery | Extracellular matrix | Chronic obstructive pulmonary disease | Alveoli | Growth factors | Phosphodiesterase | Adenosine monophosphate | Internal medicine | Cyclic AMP | Surfactants | Mammals | Gene expression | Medicine | Pulmonary fibrosis | Inhibitors | Respiratory distress syndrome | Protein expression | Indomethacin | Intracellular | Smoking
Journal Article