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Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2012, Volume 55, Issue 20, pp. 8745 - 8756
Journal Article
Journal Article
Toxicology Letters, ISSN 0378-4274, 10/2016, Volume 260, pp. 18 - 27
The heavy metal cadmium is a widespread environmental contaminant that has gained public attention due to the global increase in cadmium-containing electronic... 
Osteoblast | Cadmium | Calmodulin | Apoptosis | ACTIVATED PROTEIN-KINASE | INDUCED APOPTOSIS | CYCLE ARREST | ERK ACTIVATION | E-WASTE | IN-VITRO | GENE-EXPRESSION | TOXICOLOGY | INHIBITOR | EXPOSURE | Calmodulin - agonists | Apoptosis - drug effects | Cyclic Nucleotide Phosphodiesterases, Type 1 - chemistry | Humans | Cyclic Nucleotide Phosphodiesterases, Type 1 - antagonists & inhibitors | Environmental Pollutants - antagonists & inhibitors | Environmental Pollutants - toxicity | Cadmium - agonists | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Biomarkers - metabolism | Calmodulin - metabolism | Cadmium - toxicity | Osteoblasts - enzymology | Osteoblasts - drug effects | Cyclic Nucleotide Phosphodiesterases, Type 1 - metabolism | Phosphodiesterase Inhibitors - pharmacology | Lethal Dose 50 | Enzyme Activation - drug effects | Sulfonamides - pharmacology | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - antagonists & inhibitors | Calcium-Calmodulin-Dependent Protein Kinase Kinase - chemistry | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - chemistry | MAP Kinase Signaling System - drug effects | Naphthalimides - pharmacology | Calcium Signaling - drug effects | Calcium-Calmodulin-Dependent Protein Kinase Kinase - antagonists & inhibitors | Calcium-Calmodulin-Dependent Protein Kinase Kinase - metabolism | Cell Line, Tumor | Benzimidazoles - pharmacology | Protein Kinase Inhibitors - pharmacology | Osteoblasts - metabolism | Benzylamines - pharmacology | Calmodulin - antagonists & inhibitors | Cadmium - chemistry | Environmental Pollutants - agonists | Index Medicus | Biomedical materials | Inhibitors | Pathways | Toxicity | Activation | Kinases
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2011, Volume 46, Issue 7, pp. 2699 - 2708
Journal Article
Cellular Signalling, ISSN 0898-6568, 02/2008, Volume 20, Issue 2, pp. 359 - 374
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 52, pp. E12265 - E12274
Adrenal cortex steroids are essential for body homeostasis, and adrenal insufficiency is a life-threatening condition. Adrenal endocrine activity is maintained... 
Progenitors | Adrenal | Differentiation | PKA signaling | EZH2 | FAMILIAL GLUCOCORTICOID DEFICIENCY | PROGENITOR CELLS | differentiation | MULTIDISCIPLINARY SCIENCES | MOUSE | SELF-RENEWAL | DELETION | progenitors | ADRENOCORTICAL DEVELOPMENT | adrenal | ZONA GLOMERULOSA | MUTATIONS | EXPRESSION | REPRESSIVE COMPLEX 2 | Cyclic Nucleotide Phosphodiesterases, Type 3 - genetics | Cyclic AMP-Dependent Protein Kinase RIbeta Subunit - genetics | Adrenal Cortex - metabolism | Zona Glomerulosa - enzymology | Male | Cyclic Nucleotide Phosphodiesterases, Type 7 - genetics | Steroids - metabolism | Female | Cell Differentiation | Cyclic Nucleotide Phosphodiesterases, Type 3 - metabolism | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Zona Fasciculata - enzymology | Adrenal Cortex - enzymology | Signal Transduction | Mice, Inbred C57BL | Cyclic Nucleotide Phosphodiesterases, Type 7 - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 1 - metabolism | Zona Glomerulosa - metabolism | Zona Fasciculata - cytology | Zona Glomerulosa - cytology | Mice, Knockout | Cyclic AMP-Dependent Protein Kinase RIbeta Subunit - metabolism | Animals | Zona Fasciculata - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 1 - genetics | Methyltransferases | Adrenal glands | Physiological aspects | Physiological research | Cellular signal transduction | Research | Protein kinases | Protein kinase A | Ca2 /calmodulin-dependent phosphodiesterase | Glucocorticoids | Cortex | Adrenal cortex | Differentiation (biology) | Homeostasis | Cell differentiation | Ablation | Progenitor cells | Signaling | Adrenocorticotropic hormone | Differential equations | Cells (biology) | Stem cells | Histone methyltransferase | Steroid hormones | Steroids | Animal genetics | Cyclic Nucleotide Phosphodiesterases, Type 1 | Genomics | Cyclic Nucleotide Phosphodiesterases, Type 3 | Embryology and Organogenesis | Life Sciences | Zona Glomerulosa | Zona Fasciculata | Cyclic AMP-Dependent Protein Kinase RIbeta Subunit | Genetics | Endocrinology and metabolism | Adrenal Cortex | Biochemistry, Molecular Biology | Enhancer of Zeste Homolog 2 Protein | Human health and pathology | Development Biology | Cyclic Nucleotide Phosphodiesterases, Type 7 | Molecular biology | Cancer | Biological Sciences | PNAS Plus
Journal Article
Cell, ISSN 0092-8674, 02/2012, Volume 148, Issue 3, pp. 421 - 433
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2017, Volume 60, Issue 18, pp. 7677 - 7702
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 12/2012, Volume 123, Issue 6, pp. 1019 - 1029
Traumatic brain injury (TBI) results in significant inflammation which contributes to the evolving pathology. Previously, we have demonstrated that cyclic AMP... 
traumatic brain injury | phosphodiesterase | cAMP | fluid‐percussion | inflammation | isoform | fluid-percussion | FUNCTIONAL RECOVERY | LOCALIZATION | DIFFERENTIAL EXPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPLICE VARIANTS |