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1. Full Text Nuclear-localized cyclic nucleotide-gated channels mediate symbiotic calcium oscillations
by Charpentier, Myriam and Sun, Jongho and Martins, Teresa Vaz and Radhakrishnan, Guru V and Findlay, Kim and Soumpourou, Eleni and Thouin, Julien and Véry, Anne-Aliénor and Sanders, Dale and Morris, Richard J and Oldroyd, Giles E. D
Science, ISSN 0036-8075, 05/2016, Volume 352, Issue 6289, pp. 1102 - 1105
Nuclear-associated Ca(2+) oscillations mediate plant responses to beneficial microbial partners--namely, nitrogen-fixing rhizobial bacteria that colonize roots... 
Nucleotides, Cyclic - metabolism | Potassium Channels - metabolism | Symbiosis | Nuclear Envelope - metabolism | Medicago truncatula - genetics | Plant Roots - metabolism | Calcium Channels - metabolism | Cyclic Nucleotide-Gated Cation Channels - genetics | Medicago truncatula - metabolism | Calcium Channels - genetics | Calcium Signaling | Cyclic Nucleotide-Gated Cation Channels - metabolism | Physiological aspects | Calcium channels | Plant-pathogen relationships | Observations | Protein-protein interactions | Fungi | Legumes | Calcium | Potassium | Index Medicus | Envelopes | Roots | Oscillations | Bacteria | Channels | Life Sciences | Vegetal Biology
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2. Full Text Cyclic nucleotide-gated channel 18 is an essential Ca2+ channel in pollen tube tips for pollen tube guidance to ovules in Arabidopsis
by Qi-Fei Gao and Li-Li Gu and Hui-Qin Wang and Cui-Fang Fei and Xiang Fang and Jamshaid Hussain and Shu-Jing Sun and Jing-Yun Dong and Hongtao Liu and Yong-Fei Wang
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 11, pp. 3096 - 3101
In flowering plants, pollen tubes are guided into ovules by multiple attractants from female gametophytes to release paired sperm cells for double... 
channel | Pollen tube guidance | Arabidopsis | gradient | CNGC18 | PROTEIN | MULTIDISCIPLINARY SCIENCES | DOUBLE FERTILIZATION | PLASMA-MEMBRANE | INFLUX | THALIANA | Ca2+ channel | GROWTH | Ca2+ gradient | NITRIC-OXIDE | SYNERGID CELLS | CALCIUM GRADIENT | pollen tube guidance | REORIENTATION | Cyclic GMP - pharmacology | Arabidopsis - physiology | Calcium - metabolism | Humans | Mutation, Missense | Genetic Complementation Test | Recombinant Fusion Proteins - metabolism | Calcium Channels - physiology | Cyclic Nucleotide-Gated Cation Channels - chemistry | Cyclic GMP - analogs & derivatives | Cyclic Nucleotide-Gated Cation Channels - deficiency | Plants, Genetically Modified | HEK293 Cells | Ovule | Genes, Reporter | Second Messenger Systems | Protein Structure, Tertiary | Arabidopsis Proteins - genetics | Arabidopsis Proteins - physiology | Cyclic Nucleotide-Gated Cation Channels - genetics | Cyclic Nucleotide-Gated Cation Channels - physiology | Arabidopsis - genetics | Point Mutation | Patch-Clamp Techniques | Plant Infertility - genetics | Arabidopsis Proteins - chemistry | Membrane Potentials | Pollen Tube - growth & development | Index Medicus | Biological Sciences
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3. Full Text Multiple Calmodulin-Binding Sites Positively and Negatively Regulate Arabidopsis CYCLIC NUCLEOTIDE-GATED CHANNEL12
by Thomas A. DeFalco and Christopher B. Marshall and Kim Munro and Hong-Gu Kang and Wolfgang Moeder and Mitsuhiko Ikura and Wayne A. Snedden and Keiko Yoshioka
Plant Cell, ISSN 1040-4651, 7/2016, Volume 28, Issue 7, pp. 1738 - 1751
Ca signaling is critical to plant immunity; however, the channels involved are poorly characterized. Cyclic nucleotide-gated channels (CNGCs) are nonspecific,... 
RESEARCH ARTICLES | BIOCHEMISTRY & MOLECULAR BIOLOGY | CATION CHANNEL | TARGET RECOGNITION | PLASMA-MEMBRANE | DEPENDENT MANNER | CNG CHANNEL | PLANT SCIENCES | CELL BIOLOGY | PATHOGEN DEFENSE | PLANT IMMUNITY | STRUCTURAL BASIS | CALCIUM-PERMEABLE CHANNELS | ION CHANNELS | Calmodulin - genetics | Arabidopsis Proteins - genetics | Protein Binding - genetics | Calmodulin - metabolism | Plant Immunity - genetics | Calcium - metabolism | Cyclic Nucleotide-Gated Cation Channels - genetics | Signal Transduction - genetics | Plant Immunity - physiology | Arabidopsis - metabolism | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Signal Transduction - physiology | Binding Sites | Cyclic Nucleotide-Gated Cation Channels - metabolism | Protein Binding - physiology | Arabidopsis thaliana | Physiological aspects | Calmodulin | Index Medicus
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4. Full Text The Cyclic Nucleotide-Gated Channel CNGC14 Regulates Root Gravitropism in Arabidopsis thaliana
by Shih, Han-Wei and DePew, Cody L and Miller, Nathan D and Monshausen, Gabriele B
Current Biology, ISSN 0960-9822, 12/2015, Volume 25, Issue 23, pp. 3119 - 3125
In plant roots, auxin inhibits cell expansion, and an increase in cellular auxin levels on the lower flanks of gravistimulated roots suppresses growth and... 
SIGNAL-TRANSDUCTION | POLLEN-TUBE GROWTH | CA2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CALCIUM | CORN ROOTS | ION-CHANNEL | GUARD-CELLS | PLANT-GROWTH | AUXIN ACTION | MAIZE ROOTS | CELL BIOLOGY | Arabidopsis Proteins - genetics | Indoleacetic Acids - metabolism | Signal Transduction | Arabidopsis - growth & development | Cyclic Nucleotide-Gated Cation Channels - genetics | Plant Roots - genetics | Arabidopsis - metabolism | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Gravitropism | Plant Growth Regulators - metabolism | Plant Roots - growth & development | Cyclic Nucleotide-Gated Cation Channels - metabolism | Arabidopsis thaliana | Fluorescence | Index Medicus
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5. Full Text Plasma Membrane Cyclic Nucleotide Gated Calcium Channels Control Land Plant Thermal Sensing and Acquired Thermotolerance
by Andrija Finka and America Farinia Henriquez Cuendet and Frans J.M. Maathuis and Younousse Saidi and Pierre Goloubinoff
The Plant Cell, ISSN 1040-4651, 8/2012, Volume 24, Issue 8, pp. 3333 - 3348
Typically at dawn on a hot summer day, land plants need precise molecular thermometers to sense harmless increments in the ambient temperature to induce a... 
Shock heating | Phenotypes | Calcium | RESEARCH ARTICLES | Mosses | Protoplasts | Heat tolerance | Cell membranes | Plants | Plant cells | Seedlings | ARABIDOPSIS-THALIANA | STRESS COMBINATION | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ASCORBATE PEROXIDASE | MOSS PHYSCOMITRELLA-PATENS | PLANT SCIENCES | CELL BIOLOGY | SIGNAL-TRANSDUCTION | HEAT-SHOCK PROTEINS | CAENORHABDITIS-ELEGANS | SALICYLIC-ACID | ION-CHANNEL | Arabidopsis - physiology | Plants, Genetically Modified - growth & development | Arabidopsis - growth & development | Calcium - metabolism | Genes, Plant | Adaptation, Biological | Molecular Sequence Data | Cytoplasm - metabolism | Cell Membrane - genetics | Phylogeny | Arabidopsis Proteins - metabolism | Bryopsida - genetics | Time Factors | Gene Deletion | Gene Expression Regulation, Plant | Cell Membrane - metabolism | Cytoplasm - genetics | Cyclic Nucleotide-Gated Cation Channels - metabolism | Amino Acid Sequence | Arabidopsis Proteins - genetics | Bryopsida - physiology | Plants, Genetically Modified - genetics | Signal Transduction | Computational Biology | Cyclic Nucleotide-Gated Cation Channels - genetics | Hot Temperature | Arabidopsis - genetics | Bryopsida - growth & development | Heat-Shock Response | Phenotype | Plants, Genetically Modified - metabolism | Physiological aspects | Heat shock proteins | Calcium channels | Health aspects | Index Medicus
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6. Full Text A comparison of heat-stress transcriptome changes between wild-type Arabidopsis pollen and a heat-sensitive mutant harboring a knockout of cyclic nucleotide-gated cation channel 16 (cngc16)
by Rahmati Ishka, Maryam and Brown, Elizabeth and Weigand, Chrystle and Tillett, Richard L and Schlauch, Karen A and Miller, Gad and Harper, Jeffrey F
BMC Genomics, ISSN 1471-2164, 07/2018, Volume 19, Issue 1, pp. 549 - 549
Background: In flowering plants, the male gametophyte (pollen) is one of the most vulnerable cells to temperature stress. In Arabidopsis thaliana, a... 
Arabidopsis thaliana | Pollen | Heat stress | Cyclic nucleotide-gated cation channel 16 | Transcriptome | DROUGHT STRESS | HIGH-TEMPERATURE | MALE-STERILITY | SHOCK | RNA-SEQ | THALIANA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | GENETICS & HEREDITY | GENE-EXPRESSION | PLANTS | PROTEINS | Arabidopsis - genetics | Transcription Factors - metabolism | Pollen - metabolism | Arabidopsis Proteins - genetics | Pollen - genetics | Cyclic Nucleotide-Gated Cation Channels - genetics | Transcription Factors - genetics | Calcium Signaling - genetics | Gene Knockout Techniques | Arabidopsis - metabolism | Heat-Shock Response - genetics | Index Medicus
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7. Full Text Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice
by Lewis, Alan S and Vaidya, Sachin P and Blaiss, Cory A and Liu, Zhiqiang and Stoub, Travis R and Brager, Darrin H and Chen, Xiangdong and Bender, Roland A and Estep, Chad M and Popov, Andrey B and Kang, Catherine E and van Veldhoven, Paul P and Bayliss, Douglas A and Nicholson, Daniel A and Powell, Craig M and Johnston, Daniel and Chetkovich, Dane M
Journal of Neuroscience, ISSN 0270-6474, 05/2011, Volume 31, Issue 20, pp. 7424 - 7440
Output properties of neurons are greatly shaped by voltage-gated ion channels, whose biophysical properties and localization within axodendritic compartments... 
Hippocampus - chemistry | Depression - genetics | Protein Subunits - metabolism | Potassium Channels - metabolism | Membrane Proteins - deficiency | Cyclic Nucleotide-Gated Cation Channels - deficiency | Membrane Proteins - physiology | Gene Deletion | Peroxins | Membrane Proteins - metabolism | Potassium Channels - deficiency | Protein Subunits - physiology | Cyclic Nucleotide-Gated Cation Channels - metabolism | Mice, Inbred C57BL | Cyclic Nucleotide-Gated Cation Channels - genetics | Protein Transport - genetics | Mice, Knockout | Potassium Channels - genetics | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels | Animals | Protein Subunits - deficiency | Depression - psychology | Mice | Depression - therapy | Hippocampus - physiology | Genetic Therapy - methods | Index Medicus
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8. Full Text The gating mechanism in cyclic nucleotide-gated ion channels
by Mazzolini, Monica and Arcangeletti, Manuel and Marchesi, Arin and Napolitano, Luisa M. R and Grosa, Debora and Maity, Sourav and Anselmi, Claudio and Torre, Vincent
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 45 - 45
Cyclic nucleotide-gated (CNG) channels mediate transduction in several sensory neurons. These channels use the free energy of CNs' binding to open the pore, a... 
CNGA1 CHANNELS | C-LINKER | ROD PHOTORECEPTORS | PORE HELIX | VOLTAGE | POTASSIUM CHANNELS | MULTIDISCIPLINARY SCIENCES | CA2+-ACTIVATED K+ CHANNELS | BINDING DOMAIN | CONFORMATIONAL REARRANGEMENTS | MOLECULE FORCE SPECTROSCOPY | Position-Specific Scoring Matrices | Cyclic Nucleotide-Gated Cation Channels - genetics | Models, Molecular | Structure-Activity Relationship | Protein Folding | Amino Acid Motifs | Cyclic Nucleotide-Gated Cation Channels - chemistry | Protein Binding | Protein Conformation | Mutation | Binding Sites | Ion Channel Gating | Cyclic Nucleotide-Gated Cation Channels - metabolism | Spectroscopy | Channel opening | Channel gating | Central nervous system | Electrophysiology | Ions | Free energy | Chemical modification | Mutagenesis | Site-directed mutagenesis | Cyclic GMP | Voltage | Sensory neurons | Gating | Ion channels (cyclic nucleotide-gated) | Index Medicus | Life Sciences | Biomolecules | Pharmacology | Biophysics | Biochemistry, Molecular Biology | Pharmaceutical sciences
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9. Full Text Neuron‐restrictive silencer factor‐mediated hyperpolarization‐activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy
by McClelland, Shawn and Flynn, Corey and Dubé, Celine and Richichi, Cristina and Zha, Qinqin and Ghestem, Antoine and Esclapez, Monique and Bernard, Christophe and Baram, Tallie Z
Annals of Neurology, ISSN 0364-5134, 09/2011, Volume 70, Issue 3, pp. 454 - 465
Objective: Enduring, abnormal expression and function of the ion channel hyperpolarization-activated cyclic adenosine monophosphate gated channel type 1 (HCN1)... 
RAT HIPPOCAMPAL-NEURONS | PYRAMIDAL NEURONS | HCN CHANNELS | IN-VIVO | GENE-EXPRESSION | INDUCED STATUS EPILEPTICUS | FEBRILE SEIZURES | H-CHANNELS | TRANSCRIPTION FACTOR | NEUROSCIENCES | MICE LACKING | CLINICAL NEUROLOGY | Nucleotides, Cyclic - metabolism | Dendrites - pathology | Excitatory Amino Acid Agonists | Rats, Wistar | Channelopathies - physiopathology | Gene Expression - genetics | Potassium Channels - physiology | Status Epilepticus - chemically induced | Epilepsy, Temporal Lobe - physiopathology | Male | Channelopathies - metabolism | Repressor Proteins - antagonists & inhibitors | Kainic Acid | Repressor Proteins - physiology | CA1 Region, Hippocampal - pathology | Ion Channel Gating - physiology | Gene Expression - physiology | Epilepsy, Temporal Lobe - chemically induced | Cyclic Nucleotide-Gated Cation Channels - genetics | Cyclic Nucleotide-Gated Cation Channels - physiology | Rats | Epilepsy, Temporal Lobe - metabolism | Hippocampus - pathology | Chromatin - pathology | Potassium Channels - genetics | Channelopathies - genetics | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels | Animals | Status Epilepticus - physiopathology | Status Epilepticus - metabolism | Chromatin | Epilepsy | Index Medicus
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10. Full Text An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
by Marchesi, Arin and Gao, Xiaolong and Adaixo, Ricardo and Rheinberger, Jan and Stahlberg, Henning and Nimigean, Crina and Scheuring, Simon
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3978 - 11
Cyclic nucleotide-gated (CNG) ion channels are non-selective cation channels key to signal transduction. The free energy difference of cyclic-nucleotide... 
ATOMIC-FORCE MICROSCOPY | PROTEIN | POTASSIUM CHANNELS | MULTIDISCIPLINARY SCIENCES | MOVEMENT | K+ CHANNEL | BINDING | CNG | TOOL | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Cyclic Nucleotide-Gated Cation Channels - genetics | Models, Molecular | Crystallography, X-Ray | Rotation | Cyclic Nucleotide-Gated Cation Channels - chemistry | Cyclic AMP - chemistry | Cyclic GMP - metabolism | Cyclic GMP - chemistry | Protein Binding | Bacterial Proteins - metabolism | Protein Conformation | Microscopy, Atomic Force - methods | Cyclic AMP - metabolism | Ion Channel Gating | Cyclic Nucleotide-Gated Cation Channels - metabolism | Spirochaeta - metabolism | Atomic force microscopy | Channel opening | Channel gating | Cyclic AMP | Homology | Ions | Lipids | Helices | Free energy | Lipid bilayers | Signal transduction | Iris | Microscopy | Cyclic GMP | Ion channels | Transduction | Diaphragm | Gating | Ion channels (cyclic nucleotide-gated) | Index Medicus | Life Sciences | Biomolecules | Biophysics | Biochemistry, Molecular Biology
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11. Full Text A heat‐activated calcium‐permeable channel – Arabidopsis cyclic nucleotide‐gated ion channel 6 – is involved in heat shock responses
by Gao, Fei and Han, Xiaowei and Wu, Jianhai and Zheng, Shuzhi and Shang, Zhonglin and Sun, Daye and Zhou, Rengang and Li, Bing
The Plant Journal, ISSN 0960-7412, 06/2012, Volume 70, Issue 6, pp. 1056 - 1069
An increased concentration of cytosolic calcium ions (Ca 2+ ) is an early response by plant cells to heat shock. However, the molecular mechanism underlying... 
CNGC6 | heat shock response | thermotolerance | cAMP | Arabidopsis | permeable channel | PLASMA-MEMBRANE | CELL-DEATH | PLANT SCIENCES | SIGNAL-TRANSDUCTION | Ca2+-permeable channel | GENE | HIGHER-PLANTS | THALIANA | CA2 | HYPERSENSITIVE RESPONSE | NONSELECTIVE CATION CHANNELS | Arabidopsis - physiology | Arabidopsis Proteins - genetics | Arabidopsis Proteins - physiology | Signal Transduction | Calcium - metabolism | Cyclic Nucleotide-Gated Cation Channels - genetics | Cyclic Nucleotide-Gated Cation Channels - physiology | Arabidopsis - genetics | Heat-Shock Response | Patch-Clamp Techniques | Gene Expression Regulation, Plant | Cytosol - metabolism | Mutagenesis, Insertional | Heat-Shock Proteins - physiology | Cyclic AMP - metabolism | Index Medicus
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12. Full Text An IQ domain mediates the interaction with calmodulin in a plant cyclic nucleotide-gated channel
by Fischer, Cornelia and Kugler, Annette and Hoth, Stefan and Dietrich, Petra
Plant and Cell Physiology, ISSN 0032-0781, 04/2013, Volume 54, Issue 4, pp. 573 - 584
Cyclic nucleotide-gated channels (CNGCs) form non-selective cation entry pathways regulated by calmodulin (CaM), a universal Ca2+ sensor in eukaryotes.... 
CNGC | IQ domain | Calcium | Arabidopsis | Nuclear localization sequence | Calmodulin | ARABIDOPSIS-THALIANA | TRANSPORTER | CA2+ CHANNELS | CATION CHANNEL | PLASMA-MEMBRANE | CA2+-DEPENDENT INACTIVATION | PLANT SCIENCES | CELL BIOLOGY | CALCIUM-CHANNELS | BINDING PROTEINS | GENE-EXPRESSION | ION CHANNELS | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Calmodulin - genetics | Arabidopsis Proteins - genetics | Calmodulin - metabolism | Calcium - metabolism | Cyclic Nucleotide-Gated Cation Channels - genetics | Protein Binding | Cell Membrane - metabolism | Cyclic Nucleotide-Gated Cation Channels - metabolism | Arabidopsis - metabolism | Index Medicus | Regular Papers
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13. Full Text Genome-wide identification, evolution and expression analysis of cyclic nucleotide-gated channels in tobacco (Nicotiana tabacum L.)
by Nawaz, Zarqa and Kakar, Kaleem U and Ullah, Raqeeb and Yu, Shizou and Zhang, Jie and Shu, Qing-Yao and Ren, Xue-liang
Genomics, ISSN 0888-7543, 03/2019, Volume 111, Issue 2, pp. 142 - 158
Tobacco ( ) serve as the top leading commercial, non-food, and model crop worldwide. Cyclic nucleotide-gated channels ( ) are ligand-gated, calcium-permeable,... 
CNGC | Evolution | Tobacco | Expression | RT-qPCR | DEFENSE | PLASMA-MEMBRANE | DATABASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | GENETICS & HEREDITY | FUNCTIONAL ANALYSES | GENE FAMILY | ION CHANNELS | ARABIDOPSIS | PROTEINS | RESOURCE | Plant Proteins - genetics | Tobacco - genetics | Cyclic Nucleotide-Gated Cation Channels - genetics | Plant Proteins - metabolism | Genome, Plant | Cyclic Nucleotide-Gated Cation Channels - metabolism | Evolution, Molecular | Parenting | Anopheles | Potatoes | Analysis | Genes | Genomics | Genetic research | Genomes | Phylogeny
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