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Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 10/2014, Volume 115, Issue 10, pp. 1752 - 1761
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 09/2013, Volume 20, Issue 9, pp. 1241 - 1249
When the cell cycle becomes arrested, MTOR (mechanistic Target of Rapamycin) converts reversible arrest into senescence (geroconversion). Hyperexpression of... 
senescence | MEK | cancer | aging | cell cycle | rapamycin | PHOSPHATIDYLINOSITOL 3-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-MYC | PROLIFERATION | CELLULAR SENESCENCE | REPLICATIVE SENESCENCE | CELL BIOLOGY | ONCOGENIC RAS | GROWTH ARREST | EXPRESSION | HUMAN TUMOR-CELLS | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Cyclin D1 - metabolism | Antibiotics, Antineoplastic - pharmacology | Nitriles - pharmacology | TOR Serine-Threonine Kinases - metabolism | Humans | Cellular Senescence - drug effects | Neoplasm Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p16 | MAP Kinase Kinase 1 - genetics | Cyclin D1 - antagonists & inhibitors | TOR Serine-Threonine Kinases - genetics | RNA Interference | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Cell Cycle Checkpoints - genetics | Benzamides - pharmacology | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | TOR Serine-Threonine Kinases - drug effects | Cellular Senescence - genetics | MAP Kinase Kinase 1 - antagonists & inhibitors | Butadienes - pharmacology | Enzyme Inhibitors - pharmacology | MAP Kinase Kinase 1 - metabolism | Cyclin D1 - biosynthesis | Piperazines - pharmacology | Sirolimus - pharmacology | Cell Division - drug effects | Cyclin D1 - genetics | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Pyridines - pharmacology | RNA, Small Interfering | Original Paper
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2012, Volume 122, Issue 10, pp. 3416 - 3423
Mantle cell lymphoma is a B cell malignancy in which constitutive dysregulation of cyclin D1 and the cell cycle, disruption of DNA damage response pathways,... 
B-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | PHASE-II TRIAL | SINGLE-AGENT TEMSIROLIMUS | CYCLIN D1 | CONSTITUTIVE ACTIVATION | THERAPEUTIC TARGET | CLINICAL-TRIALS | GENE-EXPRESSION | TRANSCRIPTIONAL ROLE | AGGRESSIVE VARIANTS | Complementarity Determining Regions - genetics | Translocation, Genetic | Humans | Neoplasm Proteins - physiology | Lymphoma, Mantle-Cell - pathology | Apoptosis - genetics | DNA Repair - genetics | Molecular Targeted Therapy | Cyclin D1 - physiology | Cell Transformation, Neoplastic - genetics | Neoplastic Stem Cells - pathology | B-Lymphocytes - pathology | Neoplasm Proteins - genetics | Lymphoma, Mantle-Cell - genetics | Stem Cell Niche | Chromosomes, Human, Pair 11 - ultrastructure | Neoplasm Invasiveness | Neoplasm Proteins - biosynthesis | Genes, bcl-1 | Lymphoma, Mantle-Cell - drug therapy | Chromosomes, Human, Pair 11 - genetics | Cyclin D1 - biosynthesis | Lymphoma, Mantle-Cell - etiology | Signal Transduction - genetics | Germinal Center - pathology | Disease Progression | Genes, Immunoglobulin | Clone Cells - pathology | Gene Rearrangement, B-Lymphocyte, Heavy Chain | Signal Transduction - physiology | Chromosomes, Human, Pair 14 - ultrastructure | Chromosomes, Human, Pair 14 - genetics | Immunoglobulin Heavy Chains - genetics | DNA damage | Mantle cell lymphoma | Physiological aspects | Cyclin D proteins | Genetic aspects | Research | Risk factors | Review Series
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 03/2015, Volume 19, Issue 3, pp. 608 - 619
Journal Article
Modern Pathology, ISSN 0893-3952, 11/2016, Volume 29, Issue 11, pp. 1306 - 1312
Cyclin D1 is an important regulator of the cell cycle and overexpression of this protein by immunohistochemistry is characteristically seen in mantle cell... 
ONCOGENE | DIFFERENTIAL EXPRESSION | STAT3 | KINASE | DYSREGULATION | ANAPLASTIC LYMPHOMA | PATHOLOGY | PROTEINS | Cyclin D1 - analysis | Cyclin D1 - biosynthesis | Biomarkers, Tumor - analysis | Lymphoma, T-Cell, Peripheral - metabolism | Humans
Journal Article