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Nature Reviews Cancer, ISSN 1474-175X, 01/2017, Volume 17, Issue 2, pp. 93 - 115
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2014, Volume 53, Issue 2, pp. 193 - 208
Journal Article
Journal Article
Journal of Hematology and Oncology, ISSN 1756-8722, 04/2017, Volume 10, Issue 1, pp. 97 - 12
Uncontrolled cell division is the hallmark of cancers. Full understanding of cell cycle regulation would contribute to promising cancer therapies. In... 
Abemaciclib | Treatment resistance | CDK4/6 inhibitors | Palbociclib | Ribociclib | Breast cancer | Safety | ANTITUMOR-ACTIVITY | CELL LUNG-CANCER | G ARREST | DEPENDENT KINASE 4/6 | ONCOLOGY | STRUCTURAL BASIS | HEMATOLOGY | PHASE-I | PD 0332991 | T-CELLS | CYCLE | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Antineoplastic Agents, Immunological - pharmacokinetics | Humans | Neoplasm Proteins - physiology | Aminopyridines - pharmacokinetics | Aminopyridines - adverse effects | Pyridines - pharmacokinetics | Neoplasm Proteins - antagonists & inhibitors | Molecular Targeted Therapy | Pyridines - adverse effects | Aminopyridines - therapeutic use | Female | Purines - adverse effects | Purines - therapeutic use | Piperazines - pharmacokinetics | Benzimidazoles - adverse effects | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Benzimidazoles - therapeutic use | Pyridines - therapeutic use | Purines - pharmacokinetics | Benzimidazoles - pharmacokinetics | Therapies, Investigational | Clinical Trials as Topic | Piperazines - therapeutic use | Breast Neoplasms - drug therapy | Neoplasm Proteins - adverse effects | Piperazines - adverse effects | Cell Cycle | Antineoplastic Agents, Immunological - therapeutic use | Cyclin-Dependent Kinase 4 - physiology | Cyclin-Dependent Kinase 6 - physiology | Drug Screening Assays, Antitumor | Phosphorylation | Cell growth | Transcription factors | Lung cancer | Cyclin-dependent kinases | Cell cycle | Cell division | Growth factor receptors | Kinases
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2016, Volume 126, Issue 1, pp. 335 - 348
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2017, Volume 140, Issue 5, pp. 1147 - 1158
Journal Article
Oncogene, ISSN 0950-9232, 09/2010, Volume 29, Issue 36, pp. 5103 - 5112
Centrosome amplification (CA) contributes to carcinogenesis by generating aneuploidy. Elevated frequencies of CA in most benign breast lesions and primary... 
CHROMOSOME INSTABILITY | HUMAN-BREAST-CANCER | Ras | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-SITU HYBRIDIZATION | C-MYC | P21(WAF1/CIP1) DEFICIENCY | mammary cancers | CELL BIOLOGY | centrosome amplification | GENOMIC INSTABILITY | GENETIC INSTABILITY | ONCOLOGY | Cdk4 | GENETICS & HEREDITY | cyclin D1 | Nek2 | MMTV-RAS | TRANSGENIC MICE | Cyclin D1 - metabolism | Cell Proliferation | Epithelial Cells - metabolism | Humans | Apoptosis - genetics | Fibrocystic Breast Disease - genetics | Genes, ras - physiology | Cyclin D1 - physiology | Cell Transformation, Neoplastic - genetics | Female | Protein-Serine-Threonine Kinases - metabolism | Genes, ras - genetics | Fibrocystic Breast Disease - metabolism | Mammary Glands, Animal - pathology | Protein-Serine-Threonine Kinases - physiology | Cells, Cultured | Epithelial Cells - pathology | Mice, Transgenic | Signal Transduction - genetics | Cyclin-Dependent Kinase 4 - metabolism | Cell Transformation, Neoplastic - metabolism | Centrosome - metabolism | Animals | Centrosome - pathology | Mammary Glands, Animal - metabolism | Cyclin-Dependent Kinase 4 - physiology | Signal Transduction - physiology | Mice | NIMA-Related Kinases | Ras genes | Centrosomes | Physiological aspects | Breast cancer | Genetic aspects | Research | Protein kinases | Risk factors | Proteins | Genetics | Gene expression | Rodents | Index Medicus
Journal Article