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Cell Death and Disease, ISSN 2041-4889, 04/2019, Volume 10, Issue 4, pp. 271 - 11
.... Expression levels of cyclin-dependent kinases inhibitors (CDKIs), p21, p27, and p18 decreased during iPSC reprogramming... 
P18(INK4C) | DNA-DAMAGE | COPY NUMBER | GROWTH | CELL-CYCLE | PLURIPOTENCY | SUPPRESSION | PROTEINS | P27(KIP1) | CENTROSOME DUPLICATION | CELL BIOLOGY | Cell Division - genetics | Cyclin-Dependent Kinase Inhibitor p18 - deficiency | Transduction, Genetic | Mice, Inbred C57BL | Mice, SCID | Cyclin-Dependent Kinase Inhibitor p18 - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - deficiency | Mice, Knockout | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Animals | Cyclin-Dependent Kinase Inhibitor p18 - genetics | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Chromosome Aberrations | Cyclin-Dependent Kinase 2 - antagonists & inhibitors | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Mice, Inbred NOD | Mice | Cyclin-Dependent Kinase Inhibitor p27 - deficiency | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Cellular Reprogramming - genetics | Genomic Instability - genetics | Cyclin-Dependent Kinase Inhibitor p27 - genetics | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Cyclin-dependent kinases | DNA damage | Stem cell transplantation | Kinases | Cyclin-dependent kinase 4 | Genomic instability | Cyclin-dependent kinase | Cyclin-dependent kinase 2 | Cyclin-dependent kinase inhibitor p21 | Clonal deletion | Efficiency | Stem cells | Cell cycle | Cyclin-dependent kinase inhibitor p27 | Pluripotency | Chromosome aberrations
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 2487 - 12
.... QC treatment selectively upregulated cell cycle inhibitor p21, and downregulated F box protein Skp2 and p62/SQSTM1 expression independent of p53 status... 
PROGRAMMED CELL-DEATH | BREAST-CANCER | LUNG-CANCER | APOPTOSIS | SUPPRESSES TUMORIGENESIS | CARCINOMA CELLS | MULTIDISCIPLINARY SCIENCES | RESISTANCE | DEGRADATION | SKP2 | PROGRESSION | RNA, Small Interfering - genetics | Apoptosis - drug effects | Humans | Cyclin-Dependent Kinase Inhibitor p27 - agonists | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | RNA, Messenger - metabolism | Autophagy - drug effects | Tumor Suppressor Protein p53 - genetics | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Ovary | Quinacrine - pharmacology | Cyclin-Dependent Kinase Inhibitor p21 - genetics | S-Phase Kinase-Associated Proteins - antagonists & inhibitors | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Cell Cycle Checkpoints - genetics | Female | Antineoplastic Agents - pharmacology | Autophagy - genetics | Sequestosome-1 Protein - metabolism | Signal Transduction | RNA, Messenger - genetics | Sequestosome-1 Protein - antagonists & inhibitors | Tumor Suppressor Protein p53 - metabolism | Drug Repositioning | S-Phase Kinase-Associated Proteins - metabolism | Antimalarials - pharmacology | Sequestosome-1 Protein - genetics | Cyclin-Dependent Kinase Inhibitor p21 - agonists | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | S-Phase Kinase-Associated Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p27 - genetics | RNA, Small Interfering - metabolism | Cycle protein | GTP-binding protein | Quinacrine | p53 Protein | F-box protein | mRNA | Tumor cell lines | Autophagy | Ovarian cancer | Proteins | Cyclin-dependent kinase inhibitor p21 | Cell cycle | Phagocytosis | Apoptosis
Journal Article
Journal Article
Oncogene, ISSN 1476-5594, 2018, Volume 37, Issue 13, pp. 1759 - 1774
.... Further, NDRG2 suppression of Skp2 contributes to the inductions and stabilizations of p21 and p27, which are Skp2 target proteins for degradation... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | C-MYC | BETA-CATENIN | UBIQUITIN LIGASES | CELL BIOLOGY | BREAST-CANCER | ONCOLOGY | PATHWAY | GENETICS & HEREDITY | TUMOR-SUPPRESSOR | CELL-CYCLE | SKP2 | EXPRESSION | COLON-CARCINOMA | Intestinal Mucosa - metabolism | Adenocarcinoma - pathology | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Male | Colorectal Neoplasms - diagnosis | Cell Differentiation - genetics | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Adenocarcinoma - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Tumor Suppressor Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Adenocarcinoma - genetics | Colorectal Neoplasms - metabolism | Caco-2 Cells | Cell Proliferation - genetics | HCT116 Cells | Mice, Inbred C57BL | Biomarkers, Tumor - physiology | Signal Transduction - genetics | S-Phase Kinase-Associated Proteins - metabolism | Mice, Knockout | HT29 Cells | Tumor Suppressor Proteins - physiology | Adenocarcinoma - diagnosis | Animals | Mice, Nude | S-Phase Kinase-Associated Proteins - genetics | Mice | Colorectal Neoplasms - pathology | Cyclin-Dependent Kinase Inhibitor p27 - genetics | Intestinal Mucosa - pathology | Cyclin-dependent kinase inhibitor p21 | Clonal deletion | Colorectal carcinoma | Colorectal cancer | β-Catenin | Gene expression | Gene deletion | Cancer therapies | Ubiquitin-protein ligase | Nuclear transport | Deletion mutant
Journal Article
Nature medicine, ISSN 1546-170X, 2002, Volume 8, Issue 10, pp. 1153 - 1160
Journal Article
Scientific reports, ISSN 2045-2322, 2016, Volume 6, Issue 1, p. 30276
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2019, Volume 116, Issue 14, pp. 7005 - 7014
Journal Article
Journal Article