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Nucleic Acids Research, ISSN 0305-1048, 08/2012, Volume 40, Issue 14, pp. 6520 - 6533
P27(Kip1) (p27) is a member of the Cip/Kip family of cyclin-dependent kinase inhibitors. Recently, a new function of p27 as transcriptional regulator has been... 
Cyclin-Dependent Kinase Inhibitor p27 - metabolism | p300-CBP Transcription Factors - metabolism | Cyclin-Dependent Kinase Inhibitor p27 - chemistry | Cell Cycle | Humans | HEK293 Cells | Lysine - metabolism | Protein Interaction Domains and Motifs | Acetylation | HeLa Cells | Protein Stability
Journal Article
Haematologica, ISSN 0390-6078, 08/2017, Volume 102, Issue 8, pp. 1378 - 1389
P27 (p27) can prevent cell proliferation by inactivating cyclin-dependent kinases. This function is impaired upon phosphorylation of p27 at tyrosine residue... 
Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Cell Cycle Checkpoints | Phosphorylation | Tyrosine - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Tandem Repeat Sequences | Tumor Cells, Cultured | fms-Like Tyrosine Kinase 3 - metabolism | Protein Kinase Inhibitors - metabolism
Journal Article
Journal Article
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 07/1998, Volume 142, Issue 2, pp. 557 - 571
Journal Article
Journal Article
Blood, ISSN 0006-4971, 01/2000, Volume 95, Issue 2, pp. 619 - 626
Mantle cell lymphoma (MCL) is an aggressive neoplasm characterized by the deregulated expression of cyclin D1 by t(11;14), The molecular mechanisms responsible... 
P27(KIP1) GENE | D1 PROTEIN EXPRESSION | ZONE LYMPHOMA | TUMOR SUPPRESSION | POOR-PROGNOSIS | ACUTE LYMPHOBLASTIC-LEUKEMIA | NON-HODGKINS-LYMPHOMAS | BCL-1 REARRANGEMENT | HEMATOLOGY | MICE LACKING | AGGRESSIVE VARIANTS | Lymphoma, Mantle-Cell - surgery | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Cyclins - genetics | Lymphoma, Mantle-Cell - pathology | Multienzyme Complexes - metabolism | E2F Transcription Factors | Proteasome Endopeptidase Complex | Lymphoma, B-Cell, Marginal Zone - mortality | Tumor Suppressor Protein p53 - genetics | Lymphoma, Mantle-Cell - mortality | Cysteine Endopeptidases - metabolism | Lymphoma - pathology | Lymphoma, B-Cell, Marginal Zone - pathology | Cyclin-Dependent Kinases - antagonists & inhibitors | Lymphoma, Mantle-Cell - genetics | B-Lymphocytes - metabolism | Carrier Proteins | DNA-Binding Proteins | Biomarkers, Tumor - analysis | Cyclin-Dependent Kinase Inhibitor p21 | E2F1 Transcription Factor | Lymphoid Tissue - metabolism | Lymphoma - genetics | Survival Rate | Transcription Factors - genetics | Cyclin-Dependent Kinase Inhibitor p27 | Lymphoma, B-Cell, Marginal Zone - genetics | Transcription Factor DP1 | Ki-67 Antigen - analysis | Biomarkers, Tumor - genetics | Retinoblastoma-Binding Protein 1 | Cell Cycle Proteins | Tumor Suppressor Proteins
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/1998, Volume 95, Issue 26, pp. 15653 - 15658
Tuberous sclerosis is an autosomal dominant disorder characterized by the development of aberrant growths in many tissues and organs. Linkage analysis revealed... 
Cell growth | Neurons | Cell cycle | Cell lines | Tuberous sclerosis | Fibroblasts | Gene expression regulation | Cell cycle proteins | Cyclins | Tumors | TUBEROUS-SCLEROSIS-2 TSC2 GENE | PROTEIN-KINASE | PRODUCT | MULTIDISCIPLINARY SCIENCES | MUTATION | EKER RAT MODEL | CELL-CYCLE | DOMINANTLY INHERITED CANCER | HETEROZYGOSITY | RENAL-CARCINOMA | P27(KIP1) | Proteins | Research | Suppressor cells | Chromosomes
Journal Article