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Nature (London), ISSN 1476-4687, 09/2018, Volume 562, Issue 7725, pp. 69 - 75
Primary liver cancer represents a major health problem. It comprises hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), which differ... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Tumor Microenvironment | Apoptosis - genetics | Hepatocytes - pathology | Male | Gene Expression Profiling | Genes, myc | Hepatocytes - metabolism | Proto-Oncogene Proteins c-akt - genetics | DNA-Binding Proteins - metabolism | Carcinoma, Hepatocellular - genetics | DNA Transposable Elements - genetics | Female | Liver Neoplasms - pathology | Cell Differentiation | Cell Lineage - genetics | Disease Models, Animal | Cyclin-Dependent Kinase Inhibitor p16 - deficiency | Cytokines - metabolism | Liver Neoplasms - genetics | Carcinogenesis - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Transcription Factors - metabolism | Cholangiocarcinoma - pathology | Animals | Epigenesis, Genetic - genetics | Carcinoma, Hepatocellular - pathology | Cholangiocarcinoma - genetics | Mosaicism | Mice | Necrosis - genetics | Genes, ras | Liver cancer | Research | Carcinogenesis | Oncology, Experimental | Apoptosis | Cancer | Animal models | Cytokines | Liver | Hepatocellular carcinoma | Genomes | Metastasis | Risk analysis | Gene expression | Risk factors | Metastases | Hepatocytes | Morphology | DNA methylation | Tumorigenesis | Bioinformatics | Cholangiocarcinoma | Deoxyribonucleic acid--DNA | Tumors | Index Medicus | T-Box Domain Proteins/metabolism | Hepatocytes/pathology | DNA-Binding Proteins/metabolism | Life Sciences | Cholangiocarcinoma/pathology | Transcription Factors/metabolism | Necrosis/genetics | Cytokines/metabolism | Epigenesis, Genetic/genetics | Cyclin-Dependent Kinase Inhibitor p16/deficiency | Carcinoma, Hepatocellular/pathology | DNA Transposable Elements/genetics | Cell Lineage/genetics | T-Box Domain Proteins/genetics | Transcription Factors/genetics | Apoptosis/genetics | Proto-Oncogene Proteins c-akt/genetics | Liver Neoplasms/genetics | Cholangiocarcinoma/genetics | Liver Neoplasms/pathology | DNA-Binding Proteins/genetics | Hepatocytes/metabolism | Carcinoma, Hepatocellular/genetics | Carcinogenesis/genetics
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 7/2013, Volume 110, Issue 31, pp. 12655 - 12660
The positive transcription elongation factor b (P-TEFb) is involved in physiological and pathological events including inflammation, cancer, AIDS, and cardiac... 
T lymphocytes | Pathology | RNA | HEK293 cells | Genes | Cell lines | Antibodies | Small nuclear RNA | Gene expression regulation | HIV 1 | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | RNA-Binding Proteins - genetics | Humans | Myosin Heavy Chains - genetics | Cardiomegaly - pathology | Positive Transcriptional Elongation Factor B - metabolism | Positive Transcriptional Elongation Factor B - genetics | Myosin Heavy Chains - metabolism | RNA, Small Nuclear - genetics | Tumor Suppressor Proteins - genetics | HEK293 Cells | Cardiac Myosins - metabolism | Repressor Proteins - metabolism | Promoter Regions, Genetic | Tumor Suppressor Proteins - metabolism | Protein Structure, Secondary | Cyclin-Dependent Kinase 9 - genetics | Cardiac Myosins - genetics | Repressor Proteins - genetics | Transcription Factors - genetics | Transcription Factors - metabolism | Animals | Cyclin-Dependent Kinase 9 - metabolism | Mice | RNA, Small Nuclear - metabolism | Cardiomegaly - genetics | RNA-Binding Proteins - metabolism | Cardiomegaly - metabolism | Physiological aspects | Transcription factors | Genetic aspects | Heart enlargement | Health aspects | Myosin | Proteins | Heart | Acquired immune deficiency syndrome--AIDS | Ribonucleic acid--RNA | Cancer | Index Medicus | Life Sciences | Neurons and Cognition | Biological Sciences
Journal Article
Cancer, ISSN 0008-543X, 01/2018, Volume 124, Issue 1, pp. 84 - 94
BACKGROUND Human immunodeficiency virus–infected individuals (HIVIIs) have a higher incidence of head and neck squamous cell carcinoma (HNSCC), and clinical... 
human papillomavirus (HPV) | mutation | head and neck cancer | human immunodeficiency virus (HIV) | TP53 gene | Life Sciences & Biomedicine | Oncology | Science & Technology | Receptors, Transforming Growth Factor beta - genetics | Class I Phosphatidylinositol 3-Kinases - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | ErbB Receptors - genetics | Male | Receptor, Notch2 - genetics | Case-Control Studies | Papillomaviridae - genetics | Tumor Suppressor Protein p53 - genetics | Cyclin-Dependent Kinase Inhibitor p16 | Caspase 8 - genetics | Kelch-Like ECH-Associated Protein 1 - genetics | F-Box-WD Repeat-Containing Protein 7 - genetics | Squamous Cell Carcinoma of Head and Neck | In Situ Hybridization | Receptor, Transforming Growth Factor-beta Type II | Tumor Suppressor Proteins - genetics | Adult | Female | NF-E2-Related Factor 2 - genetics | Cadherins - genetics | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Papillomavirus Infections - complications | Protein-Serine-Threonine Kinases - genetics | Transcription Factors - genetics | Cyclin-Dependent Kinase Inhibitor p18 - genetics | Histone Methyltransferases | Cyclin D1 - genetics | Carcinoma, Squamous Cell - complications | HIV Infections - complications | HLA-A Antigens - genetics | Head and Neck Neoplasms - complications | Head and Neck Neoplasms - genetics | LIM Domain Proteins - genetics | Aged | Receptor, Notch1 - genetics | Multiplexing | Pathogenesis | Exons | p53 Protein | Genes | Viruses | Genomes | Infections | Cdc4 protein | Gene sequencing | Biological effects | Human papillomavirus | Human immunodeficiency virus--HIV | Deoxyribonucleic acid--DNA | Head | Squamous cell carcinoma | Nucleotide sequence | Epidermal growth factor receptors | Data processing | Patients | Polymerase chain reaction | Head and neck cancer | Histocompatibility antigen HLA | Mutation | Tumors | DNA sequencing | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Epigenetics, ISSN 1559-2294, 11/2010, Volume 5, Issue 8, pp. 685 - 690
..., p14ARF. Whereas p15INK4b is translated from its own independent genetic structure, ARF and p16INK4a share their second and third exons. However, ARF splices exon 2... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | ANRIL | DNA methylation | Polycomb | Histone demethylases | Senescence | ARF | Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Chromatin - metabolism | Proto-Oncogene Proteins c-mdm2 - genetics | Cyclin-Dependent Kinase 4 - genetics | Diabetes Mellitus, Type 2 - genetics | Epigenesis, Genetic | Humans | Diabetes Mellitus, Type 2 - metabolism | Genetic Loci | Cardiovascular Diseases - genetics | Cyclin-Dependent Kinase Inhibitor p15 - biosynthesis | RNA, Untranslated - genetics | Tumor Suppressor Protein p53 - genetics | Cyclin-Dependent Kinase Inhibitor p15 - genetics | ADP-Ribosylation Factors - biosynthesis | DNA Modification Methylases | Cyclin-Dependent Kinase Inhibitor p16 - biosynthesis | G1 Phase - genetics | ADP-Ribosylation Factors - genetics | Proto-Oncogene Proteins c-mdm2 - metabolism | Repressor Proteins - metabolism | Cardiovascular Diseases - metabolism | Cyclin-Dependent Kinase 6 - genetics | Tumor Suppressor Protein p53 - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Repressor Proteins - genetics | Cyclin-Dependent Kinase 6 - metabolism | Signal Transduction - genetics | Polycomb-Group Proteins | Cyclin-Dependent Kinase 4 - metabolism | Animals | Histone Demethylases | RNA, Untranslated - biosynthesis | Alzheimer Disease - metabolism | Transcription, Genetic - genetics | Alzheimer Disease - genetics | Chromatin - genetics | Index Medicus | senescence | histone demethylases | polycomb | p16INK4a | Point-of-View | p15INK4b
Journal Article
Journal Article