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Cancer Research, ISSN 0008-5472, 02/2003, Volume 63, Issue 3, pp. 586 - 592
A large number of epidemiological studies have shown that regular use of aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) results in a 40-50%... 
GASTROINTESTINAL TOXICITY | RHEUMATOID-ARTHRITIS | CARCINOGENESIS | ONCOLOGY | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | HUMAN COLON-CANCER | INTESTINAL POLYPOSIS | IRINOTECAN | FLUOROURACIL | CELL | CELECOXIB | Prostaglandin-Endoperoxide Synthases - biosynthesis | Vascular Endothelial Growth Factors | Male | Liver Neoplasms, Experimental - prevention & control | Anti-Inflammatory Agents, Non-Steroidal - blood | Lactones - pharmacology | Lactones - administration & dosage | Colorectal Neoplasms - drug therapy | Camptothecin - administration & dosage | Lymphokines - biosynthesis | Sulfones | Camptothecin - analogs & derivatives | Interleukin-12 - biosynthesis | Cyclooxygenase Inhibitors - administration & dosage | Cyclin D1 - biosynthesis | Endothelial Growth Factors - biosynthesis | Cell Division - drug effects | Drug Synergism | Membrane Proteins | Mice | Mice, Inbred BALB C | Cyclooxygenase Inhibitors - blood | Liver Neoplasms, Experimental - secondary | Neoplasm Transplantation | Vascular Endothelial Growth Factor A | Dinoprostone - biosynthesis | Cyclooxygenase 2 | Cyclooxygenase 1 | Intercellular Signaling Peptides and Proteins - biosynthesis | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Liver Neoplasms, Experimental - metabolism | Lactones - blood | Fluorouracil - administration & dosage | Trans-Activators - biosynthesis | Tumor Cells, Cultured | Cytoskeletal Proteins - biosynthesis | Colorectal Neoplasms - metabolism | Matrix Metalloproteinase 2 - biosynthesis | Matrix Metalloproteinase 9 - biosynthesis | beta Catenin | Cyclooxygenase Inhibitors - pharmacology | Animals | Cyclooxygenase 2 Inhibitors | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Interleukin-10 - biosynthesis | Colorectal Neoplasms - pathology | Isoenzymes - biosynthesis | Isoenzymes - antagonists & inhibitors
Journal Article
Journal Article
Cell, ISSN 0092-8674, 10/2016, Volume 167, Issue 2, pp. 471 - 483.e10
Journal Article
Journal Article
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 07/2008, Volume 103, Issue 1, pp. 80 - 88
The role of prostaglandin production in the control of regenerative function of endothelial progenitor cells (EPCs) has not been studied. We hypothesized that... 
Angiogenesis | Cyclooxygenase | Prostaglandins | Adult stem cells | Peroxisome proliferator-activated receptor | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | angiogenesis | CA2+-ACTIVATED K+ CHANNELS | cyclooxygenase | OUTGROWTH | adult stem cells | TRANSPLANTATION | SYNTHASE | SMOOTH-MUSCLE | INHIBITION | NITRIC-OXIDE | prostaglandins | PERIPHERAL VASCULAR DISEASE | peroxisome proliferator-activated receptor | RECEPTORS | HEMATOLOGY | EXPRESSION | Gene Expression Regulation, Enzymologic - drug effects | Neovascularization, Physiologic - drug effects | RNA, Small Interfering - genetics | Cell Proliferation | Iloprost - pharmacology | Epoprostenol - biosynthesis | Humans | Middle Aged | Culture Media, Conditioned - pharmacology | Male | Stem Cells - cytology | Gene Expression Regulation, Enzymologic - physiology | Stem Cells - enzymology | Adult | Cyclooxygenase 1 - genetics | Cyclooxygenase 1 - biosynthesis | Vasodilator Agents - pharmacology | Cells, Cultured | Enzyme Activation - drug effects | Indomethacin - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Neovascularization, Physiologic - physiology | Regeneration | Tumor Necrosis Factor-alpha - pharmacology | Endothelial Cells - cytology | PPAR delta - agonists | Leukocytes, Mononuclear - cytology | Leukocytes, Mononuclear - enzymology | Thiazoles - pharmacology | Endothelial Cells - enzymology | Enzyme Activation - physiology | peroxisome-proliferator activated receptor
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/1999, Volume 96, Issue 1, pp. 272 - 277
Prostaglandins (PG) are synthesized by two isoforms of the enzyme PG G/H synthase [cyclooxygenase (COX)]. To examine selectivity of tolerated doses of an... 
Volunteerism | Excretion | Prostaglandins | Cyclooxygenase inhibitors | Placebos | Biosynthesis | Biochemistry | Dosage | Platelets | Blood plasma | Monocytes | Celecoxib | Ibuprofen | monocytes | celecoxib | ENDOPEROXIDE-H SYNTHASE-1 | MULTIDISCIPLINARY SCIENCES | ibuprofen | platelets | HUMAN ENDOTHELIAL-CELLS | PRESYSTEMIC ACETYLATION | LOW-DOSE ASPIRIN | MESSENGER-RNA | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | PROSTAGLANDIN-G/H SYNTHASE | prostaglandins | ALVEOLAR MACROPHAGES | BLOOD MONOCYTES | CDNA CLONING | Isoenzymes - blood | 6-Ketoprostaglandin F1 alpha - analogs & derivatives | Epoprostenol - biosynthesis | Cyclooxygenase 2 | Humans | Middle Aged | Cyclooxygenase 1 | Male | Isoenzymes - metabolism | Platelet Aggregation Inhibitors - pharmacology | Adult | Female | Platelet Aggregation - drug effects | Ibuprofen - pharmacology | Pyrazoles | Ibuprofen - pharmacokinetics | Prostaglandin-Endoperoxide Synthases - drug effects | Sulfonamides - pharmacology | Prostaglandin-Endoperoxide Synthases - blood | Thromboxane B2 - analogs & derivatives | Sulfonamides - pharmacokinetics | Cyclooxygenase Inhibitors - pharmacology | Dinoprostone - metabolism | Membrane Proteins | Monocytes - enzymology | Cyclooxygenase 2 Inhibitors | 6-Ketoprostaglandin F1 alpha - urine | Prostaglandin-Endoperoxide Synthases - metabolism | Thromboxane B2 - urine | Isoenzymes - drug effects | Thromboxane B2 - blood | Oxidases | Prostacyclin | Research | Analysis | Biological Sciences
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 03/2018, Volume 642, pp. 1 - 9
Members of Chordata peroxidase subfamily [1] expressed in mammals, including myeloperoxidase (MPO), eosinophil peroxidase (EPO), lactoperoxidase (LPO), and... 
Myeloperoxidase | Peroxidases | Cyclooxygenase-peroxidase protein family | Heme proteins | HUMAN MYELOID CELLS | HUMAN THYROID PEROXIDASE | COLONY-STIMULATING FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISULFIDE BOND | HUMAN LYSOZYME | HUMAN THYROPEROXIDASE | LEUKEMIA HL-60 CELLS | BIOPHYSICS