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Biochimica et biophysica acta. General subjects, ISSN 0304-4165, 05/2018, Volume 1862, Issue 5, pp. 1069 - 1078
Journal Article
ONCOGENE, ISSN 0950-9232, 07/2007, Volume 26, Issue 34, pp. 4999 - 5009
Prostaglandin E-2 plays multiple roles both in the physiology and the physiopathology of human brain, which are not completely understood. We have identi. ed... 
prostaglandin synthase | PROSTAGLANDIN-E SYNTHASE | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | cyclooxygenase | apoptosis | NEURODEGENERATION | DEATH | NEUROTOXICITY | PGE | CELL BIOLOGY | COLON-CANCER | INHIBITION | ONCOLOGY | GENETICS & HEREDITY | Bax | CYCLOOXYGENASE-2 EXPRESSION | PROGNOSTIC-SIGNIFICANCE | gliomas | PARKINSONS-DISEASE
Journal Article
Circulation Research, ISSN 0009-7330, 08/2009, Volume 105, Issue 4, pp. 365 - 374
RATIONALE:The recent emergence of hydrogen sulfide (H2S) as a potent cardioprotective signaling molecule necessitates the elucidation of its cytoprotective... 
Hydrogen sulfide | Myocardial infarction | Cardioprotection | Nrf2 | Antioxidant signaling | PROTEIN-KINASE-C | OXIDATIVE STRESS | ISCHEMIA/REPERFUSION INJURY | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | myocardial infarction | INDUCTION | antioxidant signaling | ISCHEMIA-REPERFUSION INJURY | JAK-STAT PATHWAY | hydrogen sulfide | ANTIOXIDANT | cardioprotection | PERIPHERAL VASCULAR DISEASE | MYOCARDIAL INJURY | RAT-HEART | HEMATOLOGY | HSP90 Heat-Shock Proteins - biosynthesis | Oxidative Stress | Air Pollutants - pharmacology | Male | Cyclooxygenase 2 - biosynthesis | bcl-Associated Death Protein - biosynthesis | Cell Nucleus - metabolism | Thioredoxins - biosynthesis | Time Factors | Protein Kinase C - metabolism | bcl-X Protein - biosynthesis | Phosphorylation - drug effects | HSP70 Heat-Shock Proteins - biosynthesis | Hydrogen Sulfide - pharmacology | Heme Oxygenase-1 - biosynthesis | Cardiotonic Agents - pharmacology | Myocardial Infarction - metabolism | Mice, Inbred ICR | Mice, Knockout | Gene Expression Regulation - drug effects | STAT3 Transcription Factor - biosynthesis | Myocardial Reperfusion Injury - metabolism | Animals | Signal Transduction - drug effects | Active Transport, Cell Nucleus - drug effects | NF-E2-Related Factor 2 - metabolism | Mice | Myocardial Infarction - prevention & control | Troponin I - metabolism | Myocardial Reperfusion Injury - prevention & control | Index Medicus
Journal Article
TOXICON, ISSN 0041-0101, 02/2011, Volume 57, Issue 2, pp. 288 - 296
In this study, the production of prostaglandin E-2 (PGE(2)) and up-regulation in cyclooxygenase (COX) pathway induced by a phospholipase A(2) (PLA(2)),... 
GROUP-V | INDUCIBLE CYCLOOXYGENASE | Phosholipase A | MACROPHAGES | Prostaglandin E-2 | FATTY-ACIDS | ARACHIDONIC-ACID | GROUP-IV | PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2 | Cyclooxygenase | E-2 GENERATION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Neutrophil | Myotoxin-III | NF-KAPPA-B | POLYMORPHONUCLEAR NEUTROPHILS
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2012, Volume 18, Issue 8, pp. 2220 - 2229
Purpose: Because of poor prognosis and development of resistance against chemotherapeutic drugs, the existing treatment modalities for gastric cancer are... 
COLORECTAL ADENOCARCINOMA CELLS | APOPTOSIS | INVASION | PROTEIN | ONCOLOGY | SIGNALING PATHWAY | KINASE | CHEMOPREVENTION | SECRETION | SUPPRESSION | CHEMOTHERAPY | Vascular Endothelial Growth Factor A - biosynthesis | Apoptosis - drug effects | Capecitabine | Humans | Stomach Neoplasms - metabolism | Vitamin E - analogs & derivatives | Deoxycytidine - pharmacology | NF-kappa B - metabolism | Stomach Neoplasms - pathology | Chromans - metabolism | Cyclooxygenase 2 - biosynthesis | Chromans - pharmacology | Intercellular Adhesion Molecule-1 - biosynthesis | bcl-X Protein - biosynthesis | Gene Expression Regulation, Neoplastic - drug effects | Disease Models, Animal | Inhibitor of Apoptosis Proteins - biosynthesis | Matrix Metalloproteinase 9 - biosynthesis | Fluorouracil - analogs & derivatives | Antineoplastic Combined Chemotherapy Protocols | Cyclin D1 - biosynthesis | Mitochondria - metabolism | Stomach Neoplasms - drug therapy | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Xenograft Model Antitumor Assays | Animals | Repressor Proteins - biosynthesis | Receptors, CXCR4 - biosynthesis | Mice, Nude | Neovascularization, Pathologic - drug therapy | Cell Line, Tumor | Vitamin E - metabolism | Ki-67 Antigen - biosynthesis | Cell Proliferation - drug effects | Fluorouracil - pharmacology | Mice | Platelet Endothelial Cell Adhesion Molecule-1 - biosynthesis | Deoxycytidine - analogs & derivatives | Vitamin E - pharmacology | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 03/2007, Volume 115, Issue 12, pp. 1599 - 1608
Background-Stroke is the second to third leading cause of death. Toll-like receptor 4 (TLR4) is a signaling receptor in innate immunity that is a specific... 
Infection | Cerebral ischemia | Stroke | Nitric oxide synthase | Inflammation | Metalloproteinases | Immune system | infection | CARDIAC & CARDIOVASCULAR SYSTEMS | LIPID-PEROXIDATION | FOCAL CEREBRAL-ISCHEMIA | metalloproteinases | stroke | NITRIC-OXIDE-SYNTHASE | MATRIX METALLOPROTEINASES | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTOR-4 | MESSENGER-RNA | inflammation | cerebral ischemia | immune system | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | nitric oxide synthase | HEMATOLOGY | PATTERN-RECOGNITION RECEPTORS | INNATE IMMUNITY | Interferons - biosynthesis | Nitric Oxide Synthase Type II - biosynthesis | Oxidative Stress | Tumor Necrosis Factor-alpha - genetics | Nitrobenzenes - therapeutic use | Male | NF-kappa B - metabolism | Interleukin-1beta - genetics | Cyclooxygenase 2 - biosynthesis | Toll-Like Receptor 4 - deficiency | Cyclooxygenase 2 - genetics | Infarction, Middle Cerebral Artery - complications | Matrix Metalloproteinase 9 - genetics | Cyclooxygenase 2 Inhibitors - therapeutic use | Brain Damage, Chronic - metabolism | Interferons - genetics | Interferon Regulatory Factor-1 - biosynthesis | Encephalitis - pathology | Mice, Knockout | Toll-Like Receptor 4 - physiology | Brain Damage, Chronic - etiology | Cerebral Infarction - etiology | Brain Chemistry | Mice | Tumor Necrosis Factor-alpha - biosynthesis | Brain Damage, Chronic - prevention & control | Encephalitis - etiology | Dinoprostone - analysis | Infarction, Middle Cerebral Artery - metabolism | Cerebral Infarction - metabolism | Encephalitis - drug therapy | Nitric Oxide Synthase Type II - antagonists & inhibitors | Encephalitis - metabolism | Inflammation Mediators - metabolism | Nerve Tissue Proteins - biosynthesis | Interleukin-1beta - biosynthesis | Brain Damage, Chronic - pathology | Cerebral Infarction - pathology | Matrix Metalloproteinase 9 - biosynthesis | Mice, Inbred C57BL | Gene Expression Regulation | Infarction, Middle Cerebral Artery - pathology | Nerve Tissue Proteins - genetics | Mice, Inbred C3H | Interferon Regulatory Factor-1 - genetics | Animals | Nitric Oxide Synthase Type II - genetics | Sulfonamides - therapeutic use | Lipid Peroxidation | Nitric Oxide - metabolism | Stroke (Disease) | Complications and side effects | Patient outcomes | Physiological aspects | Development and progression | Research | Chemokines | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 03/1997, Volume 272, Issue 12, pp. 8083 - 8089
The inflammatory cytokine interleukin 1 beta (IL-1 beta) induces both cyclooxygenase-2 (Cox-2) and the inducible nitric-oxide synthase (iNOS) with increases in... 
SYNTHASE | PHOSPHORYLATION | CLONING | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE DISRUPTION | MAP KINASES | HEAT-SHOCK | INDUCTION | CYCLOOXYGENASE | EXPRESSION | SMOOTH-MUSCLE CELLS
Journal Article
Journal of Pineal Research, ISSN 0742-3098, 08/2012, Volume 53, Issue 1, pp. 77 - 90
Journal Article
Journal Article
Journal Article
Journal Article