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Nature Immunology, ISSN 1529-2908, 11/2012, Volume 13, Issue 11, pp. 1072 - 1082
Hematopoietic stem and progenitor cells (HSPCs) are regulated by various bone marrow stromal cell types. Here we identified rare activated bone marrow... 
PROGENITOR CELLS | OXIDATIVE STRESS | MICROENVIRONMENT | MYELOPOIESIS | RECEPTOR LIGANDS | NICHE | STEM-CELL | IMMUNOLOGY | STROMAL CELLS | RECONSTITUTION | PROSTAGLANDIN-E2 | Cell Communication - immunology | Gamma Rays | Bone Marrow - immunology | Mesenchymal Stromal Cells - radiation effects | Reactive Oxygen Species - metabolism | Dinoprostone - biosynthesis | Monocytes - cytology | Monocytes - radiation effects | Cell Survival - genetics | Bone Marrow - radiation effects | Monocytes - immunology | Actins - immunology | Dinoprostone - immunology | Cell Movement - genetics | Proto-Oncogene Proteins c-akt - genetics | Actins - genetics | Mesenchymal Stromal Cells - immunology | Cell Movement - immunology | Signal Transduction - immunology | Hematopoietic Stem Cells - immunology | Mesenchymal Stromal Cells - cytology | Chemokine CXCL12 - genetics | Cyclooxygenase 2 - genetics | Reactive Oxygen Species - immunology | Bone Marrow - metabolism | Macrophages - radiation effects | Signal Transduction - radiation effects | Cyclooxygenase 2 - immunology | Hematopoietic Stem Cells - radiation effects | Chemokine CXCL12 - immunology | Macrophages - immunology | Gene Expression Regulation - immunology | Signal Transduction - genetics | Cell Communication - genetics | Macrophages - cytology | Cell Survival - immunology | Cell Survival - radiation effects | Animals | Proto-Oncogene Proteins c-akt - immunology | Hematopoietic Stem Cells - cytology | Gene Expression Regulation - radiation effects | Mice
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2018, Volume 200, Issue 11, pp. 3729 - 3738
Journal Article
Biochimica et biophysica acta. General subjects, ISSN 0304-4165, 05/2018, Volume 1862, Issue 5, pp. 1069 - 1078
Journal Article
Journal of Clinical Endocrinology and Metabolism, ISSN 0021-972X, 05/2017, Volume 102, Issue 5, pp. 1468 - 1477
Context: Increasing evidences suggest a correlation between gut and type 1 diabetes (T1D). Objective: The objective of this study is to evaluate the gut... 
INCREASED INTESTINAL PERMEABILITY | HEALTHY-CHILDREN | DIFFERS | FECAL MICROBIOTA | DISEASE | ENDOCRINOLOGY & METABOLISM | CELL AUTOIMMUNITY | GUT MICROBIOTA | MELLITUS | ONSET | Receptors, CCR2 - genetics | Serum Amyloid P-Component - immunology | Receptors, CCR2 - immunology | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Transcriptome | Child, Preschool | Male | Monocyte Chemoattractant Proteins - immunology | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Interleukin-4 Receptor alpha Subunit - genetics | Young Adult | Celiac Disease - microbiology | Cyclooxygenase 2 - genetics | Intestinal Mucosa - immunology | Diabetes Mellitus, Type 1 - microbiology | Tumor Necrosis Factor-alpha - immunology | Child | Real-Time Polymerase Chain Reaction | Duodenum - immunology | Vascular Endothelial Growth Factor A - immunology | C-Reactive Protein - genetics | Intestinal Mucosa - microbiology | Reverse Transcriptase Polymerase Chain Reaction | Monocyte Chemoattractant Proteins - genetics | Chemokine CCL22 - genetics | Chemokine CCL19 - genetics | Adolescent | RNA, Ribosomal, 16S - genetics | C-Reactive Protein - immunology | Antigens, CD - immunology | Infant | Case-Control Studies | Duodenum - microbiology | Chemokine CCL22 - immunology | Celiac Disease - immunology | Adult | Female | Diabetes Mellitus, Type 1 - immunology | Chemokine CCL19 - immunology | Cyclooxygenase 2 - immunology | Antigens, Differentiation, Myelomonocytic - immunology | Diabetes Mellitus, Type 1 - genetics | Gastrointestinal Microbiome - genetics | Interleukin-4 Receptor alpha Subunit - immunology | Antigens, Differentiation, Myelomonocytic - genetics | Serum Amyloid P-Component - genetics | Aged | Immunohistochemistry | CC chemokine receptors | rRNA 16S | CCL19 protein | Pathogenesis | Mucosa | Microbiomes | Diabetes mellitus (insulin dependent) | Macrophages | Small intestine | Gene sequencing | CCL22 protein | Microbiota | CCR2 protein | Intestine | Interleukin 4 receptors | Digestive tract | Duodenum | Digestive system | Abnormalities | Diabetes mellitus | Inflammation | Tumor necrosis factor-α | Gene expression | Ribonucleic acid--RNA | Disease control | Patients | Celiac disease | Biopsy | Infiltration | Diabetes | Cyclooxygenase-2 | Autoimmune diseases | Monocyte chemoattractant protein 1
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2018, Volume 201, Issue 3, pp. 916 - 929
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2012, Volume 189, Issue 11, pp. 5402 - 5410
Given that TLRs and sphingosine-1-phosphate (S1P) are key players in inflammation, we explored the potential interplay between TLRs and S1P in the... 
IMMUNITY | CYTOKINES | S1P | PATHWAY | ALPHA | IMMUNOLOGY | RECEPTORS | VASCULAR ENDOTHELIUM | EXPRESSION | HIGH-DENSITY-LIPOPROTEIN | SPHINGOSINE 1-PHOSPHATE | Epoprostenol - genetics | Inflammation - pathology | Humans | NF-kappa B - immunology | Human Umbilical Vein Endothelial Cells - immunology | Endothelium, Vascular - drug effects | Extracellular Signal-Regulated MAP Kinases - genetics | Extracellular Signal-Regulated MAP Kinases - immunology | Cyclooxygenase 2 - genetics | E-Selectin - genetics | Leukocytes, Mononuclear - immunology | Lysophospholipids - pharmacology | Cyclooxygenase 2 - immunology | Endothelium, Vascular - immunology | Human Umbilical Vein Endothelial Cells - drug effects | Leukocytes, Mononuclear - drug effects | Interleukin-6 - genetics | Intercellular Adhesion Molecule-1 - immunology | Toll-Like Receptors - immunology | Cells, Cultured | p38 Mitogen-Activated Protein Kinases - genetics | E-Selectin - immunology | Inflammation - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Cell Adhesion - drug effects | Organ Specificity | Drug Synergism | Gene Expression Regulation - drug effects | Sphingosine - pharmacology | Leukocytes, Mononuclear - pathology | Sphingosine - analogs & derivatives | NF-kappa B - genetics | Signal Transduction - drug effects | Intercellular Adhesion Molecule-1 - genetics | Toll-Like Receptors - genetics | Interleukin-6 - immunology | Lipopolysaccharides - pharmacology | Inflammation - genetics | Endothelium, Vascular - pathology | Human Umbilical Vein Endothelial Cells - pathology | Epoprostenol - immunology
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 423 - 432.e8
Background The immunomodulatory and anti-inflammatory functions of mesenchymal stem cells (MSCs) have been demonstrated in several autoimmune/inflammatory... 
Allergy and Immunology | Allergy | allergic conjunctivitis | histamine | mesenchymal stem cells | stems cells | B cells | mast cells | RECONSTRUCTION | CONTACT HYPERSENSITIVITY | RECEPTOR | IMMUNOLOGY | SUPPRESSION | MATURATION | TRANSPLANTATION | MURINE MODEL | RESPONSES | INFLAMMATION | VE-CADHERIN | Ambrosia - chemistry | RNA, Small Interfering - genetics | Tumor Necrosis Factor-alpha - genetics | Capillary Permeability - drug effects | Conjunctivitis, Allergic - drug therapy | Capillary Permeability - immunology | Culture Media, Conditioned - pharmacology | Pollen - immunology | Mesenchymal Stromal Cells - immunology | Histamine - metabolism | Conjunctiva - pathology | Immunoglobulin E - genetics | RNA, Small Interfering - immunology | Cyclooxygenase 2 - genetics | Bone Marrow Cells - immunology | Tumor Necrosis Factor-alpha - immunology | Bone Marrow Cells - drug effects | Cell Differentiation | B-Lymphocytes - pathology | Interleukin-4 - genetics | Cyclooxygenase 2 - immunology | Mesenchymal Stromal Cells - drug effects | Conjunctivitis, Allergic - chemically induced | Conjunctiva - immunology | Signal Transduction | Bone Marrow Cells - pathology | Gene Expression Regulation | Ambrosia - immunology | Conjunctivitis, Allergic - genetics | B-Lymphocytes - drug effects | Interleukin-4 - immunology | Tumor Necrosis Factor-alpha - pharmacology | Animals | B-Lymphocytes - immunology | Conjunctiva - drug effects | Mice | Mice, Inbred BALB C | Mesenchymal Stromal Cells - pathology | Primary Cell Culture | Conjunctivitis, Allergic - immunology
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2015, Volume 467, Issue 2, pp. 235 - 241
Monocytes and macrophages are important effectors and regulators of inflammation, and both their differentiation and activation are regulated strictly in... 
Inflammation | Monocyte | Cytokine production | Peritoneal cells | Macrophage | ACTIVATION | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | LEUKEMIA DEVELOPMENT | PATHOGENESIS | BIOPHYSICS | HEMATOPOIETIC STEM-CELLS | ANGPTL2 | EXPRESSION | Inflammation - pathology | Humans | Tumor Necrosis Factor-alpha - genetics | Macrophages, Peritoneal - pathology | NF-kappa B - immunology | Monocytes - immunology | Interleukin-1beta - genetics | Extracellular Signal-Regulated MAP Kinases - genetics | Extracellular Signal-Regulated MAP Kinases - immunology | Angiopoietins - immunology | Angiopoietin-like Proteins | Nitric Oxide Synthase Type II - immunology | Cyclooxygenase 2 - genetics | HEK293 Cells | Monocytes - pathology | Tumor Necrosis Factor-alpha - immunology | Cyclooxygenase 2 - immunology | Interleukin-6 - genetics | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Interleukin-1beta - immunology | Macrophages, Peritoneal - immunology | p38 Mitogen-Activated Protein Kinases - genetics | Inflammation - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Interleukin-6 - immunology | Inflammation - genetics | Mice | Primary Cell Culture | Angiopoietins - genetics | Physiological aspects | Development and progression | Nitric oxide | BLOOD FORMATION | ANGIOGENESIS | NEOPLASMS | NITRIC OXIDE | TRANSCRIPTION | MONOCYTES | BONE MARROW | 60 APPLIED LIFE SCIENCES | SKELETON | LYMPHOKINES | PROSTAGLANDINS | INFLAMMATION | GENES
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 07/2014, Volume 66, Issue 7, pp. 1779 - 1788
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 05/2012, Volume 188, Issue 9, pp. 4690 - 4700
Immune cells are known to express specific recognition molecules for cell surface glycans. However, mechanisms involved in glycan-mediated cell cell... 
6-SULFO LEWIS-X | NATURAL-KILLER-CELLS | INCOMPLETE-SYNTHESIS | CARBOHYDRATE DETERMINANTS | CYCLOOXYGENASE-2 | COLORECTAL-CANCER | INHIBITORY RECEPTOR | IMMUNOLOGY | SIALYL-LEWIS | L-SELECTIN LIGAND | MOUSE MODELS | Antigens, CD - immunology | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Antigens, CD - biosynthesis | Stromal Cells - pathology | Humans | Colon - immunology | Lectins - biosynthesis | Colonic Neoplasms - metabolism | Cyclooxygenase 2 - biosynthesis | Colonic Neoplasms - immunology | Intestinal Mucosa - immunology | Inflammation Mediators - metabolism | CD8-Positive T-Lymphocytes - metabolism | Cyclooxygenase 2 - immunology | Antigens, Differentiation, Myelomonocytic - immunology | Macrophages - immunology | Inflammation Mediators - immunology | Antigens, Differentiation, Myelomonocytic - biosynthesis | Lectins - immunology | Macrophages - pathology | Colon - pathology | Gene Expression Regulation - immunology | Stromal Cells - metabolism | Epithelial Cells - pathology | Stromal Cells - immunology | Glycosylation | Oligosaccharides - metabolism | Cell Transformation, Neoplastic - metabolism | CD8-Positive T-Lymphocytes - physiology | Colon - metabolism | Cell Transformation, Neoplastic - immunology | Macrophages - metabolism | Animals | Colonic Neoplasms - pathology | Epithelial Cells - immunology | Oligosaccharides - immunology | Lipopolysaccharides - pharmacology | Cell Line, Tumor | Sialic Acid Binding Immunoglobulin-like Lectins | Mice | CD8-Positive T-Lymphocytes - immunology | Cell Transformation, Neoplastic - pathology | Intestinal Mucosa - pathology | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2016, Volume 291, Issue 13, pp. 7070 - 7086
In Candida albicans-infected resident peritoneal macrophages, activation of group IVA cytosolic phospholipase A2(cPLA2α) by calcium- and mitogen-activated... 
Group IV Phospholipases A2 - genetics | Dinoprostone - biosynthesis | Epoprostenol - biosynthesis | Nuclear Receptor Subfamily 4, Group A, Member 2 - immunology | Tumor Necrosis Factor-alpha - genetics | Receptors, Prostaglandin - immunology | Nuclear Receptor Subfamily 4, Group A, Member 2 - genetics | Membrane Proteins - deficiency | Receptors, Prostaglandin - genetics | Cyclic AMP - analogs & derivatives | Cyclooxygenase 2 - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Tumor Necrosis Factor-alpha - immunology | Cyclic AMP Response Element-Binding Protein - immunology | Candida albicans - physiology | Cyclic AMP - metabolism | Cyclooxygenase 2 - immunology | Macrophages, Peritoneal - drug effects | Receptors, Prostaglandin - antagonists & inhibitors | Cyclooxygenase 1 - immunology | Group IV Phospholipases A2 - deficiency | Mitogen-Activated Protein Kinase 3 - immunology | Cyclooxygenase 1 - genetics | Mitogen-Activated Protein Kinase 1 - immunology | Group IV Phospholipases A2 - immunology | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | Membrane Proteins - genetics | 8-Bromo Cyclic Adenosine Monophosphate - pharmacology | Gene Expression Regulation | Macrophages, Peritoneal - immunology | p38 Mitogen-Activated Protein Kinases - genetics | Membrane Proteins - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Mice, Knockout | Cyclic AMP - pharmacology | Host-Pathogen Interactions | Cyclic AMP Response Element-Binding Protein - genetics | Animals | Macrophages, Peritoneal - microbiology | Receptors, Prostaglandin - agonists | Cyclooxygenase 1 - deficiency | Interleukin-10 - genetics | Mice | Protein Kinase Inhibitors - pharmacology | Primary Cell Culture | Interleukin-10 - immunology | Candida albicans | cAMP-response element-binding protein (CREB) | phospholipase A | prostaglandin | c-Jun N-terminal kinase (JNK) | mitogen-activated protein kinase (MAPK) | cyclic AMP (cAMP) | p38 MAPK | extracellular signal-regulated kinase (ERK)
Journal Article