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Journal Article
Clinical and experimental pharmacology & physiology, ISSN 1440-1681, 02/2008, Volume 35, Issue 2, pp. 192 - 200
SUMMARY • The present study evaluated the effect of diabetes, hypercholesterolaemia and their combination on the contribution of nitric oxide (NO) and... 
endothelium-derived hyperpolarising factor | diabetes | endothelium-dependent relaxation | hypercholesterolaemia | superoxide anion | endothelium‐derived hyperpolarising factor | endothelium‐dependent relaxation | Superoxide anion | Diabetes | Hypercholesterolaemia | Endothelium-dependent relaxation | Endothelium-derived hyperpolarising factor | Pharmacology & Pharmacy | Physiology | Life Sciences & Biomedicine | Science & Technology | Body Weight | Oxidative Stress | Cholesterol - blood | Diabetes Mellitus, Type 1 - metabolism | Nitric Oxide Synthase - antagonists & inhibitors | Male | Guanylate Cyclase - antagonists & inhibitors | Nitroprusside - pharmacology | Apamin - pharmacology | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Charybdotoxin - pharmacology | Oxadiazoles - pharmacology | Potassium Channels, Calcium-Activated - metabolism | Superoxides - metabolism | Aorta, Thoracic - drug effects | Biological Factors - metabolism | Diabetes Mellitus, Experimental - metabolism | Potassium Channel Blockers - pharmacology | Diabetes Mellitus, Experimental - physiopathology | Disease Models, Animal | Vasodilator Agents - pharmacology | Acetylcholine - pharmacology | Diabetes Mellitus, Type 1 - physiopathology | Enzyme Inhibitors - pharmacology | Aorta, Thoracic - metabolism | Rats | Guanylate Cyclase - metabolism | Soluble Guanylyl Cyclase | Aorta, Thoracic - physiopathology | Rats, Sprague-Dawley | Indomethacin - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Nitroarginine - pharmacology | Aorta, Thoracic - enzymology | Animals | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Hypercholesterolemia - physiopathology | Nitric Oxide Synthase - metabolism | Potassium Channels, Calcium-Activated - antagonists & inhibitors | Vasodilation - drug effects | Blood Glucose - metabolism | Nitric Oxide - metabolism | Hypercholesterolemia - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Charybdotoxin, pharmacology | Diabetes Mellitus, Type 1, physiopathology | Nitric Oxide Synthase, antagonists and inhibitors | Aorta, Thoracic, physiopathology | Potassium Channels, Calcium-Activated, antagonists and inhibitors | Hypercholesterolemia, metabolism | Quinoxalines, pharmacology | Enzyme Inhibitors, pharmacology | Aorta, Thoracic, drug effects | Aorta, Thoracic, metabolism | Receptors, Cytoplasmic and Nuclear, antagonists and inhibitors | Vasodilator Agents, pharmacology | Vasodilation | Nitric Oxide Synthase, metabolism | Cyclooxygenase Inhibitors, pharmacology | Apamin, pharmacology | Nitroarginine, pharmacology | Potassium Channel Blockers, pharmacology | Vasodilation, drug effects | Cholesterol, blood | Receptors, Cytoplasmic and Nuclear, metabolism | Biological Factors, metabolism | Diabetes Mellitus, Experimental, physiopathology | Nitric Oxide, metabolism | Acetylcholine, pharmacology | Diabetes Mellitus, Experimental, metabolism | Nitroprusside, pharmacology | Oxadiazoles, pharmacology | Blood Glucose, metabolism | Potassium Channels, Calcium-Activated, metabolism | Aorta, Thoracic, enzymology | Hypercholesterolemia, physiopathology | Diabetes Mellitus, Type 1, metabolism | Guanylate Cyclase, antagonists and inhibitors | Guanylate Cyclase, metabolism | Superoxides, metabolism | Indomethacin, pharmacology | Superoxide | Hypercholesterolemia | Endothelium-derived relaxing factors | Type 1 diabetes | Endothelium | Index Medicus
Journal Article
Journal Article
Food chemistry, ISSN 0308-8146, 03/2017, Volume 218, pp. 15 - 21
•Alkaline hot water increased the yield of orange peel extract.•Orange peel extract have higher anti-inflammatory activity than their equivalent flavonoid... 
Nchenpi | Antioxidant | Nobiletin | Orange peel extract | Flavonoid | Anti-inflammation | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Nutrition & Dietetics | Food Science & Technology | Science & Technology | Flavones - analysis | Flavonoids - analysis | Citrus - chemistry | Drugs, Chinese Herbal - pharmacology | Chromatography, High Pressure Liquid | Nitric Oxide - analysis | Plant Extracts - analysis | Anti-Inflammatory Agents - analysis | Nitric Oxide Synthase Type II - antagonists & inhibitors | China | Flavonoids - pharmacology | Amidines - analysis | Antioxidants - analysis | Flavones - pharmacology | Picrates - analysis | Phenols - pharmacology | Cell Survival - drug effects | Cyclooxygenase 2 Inhibitors - pharmacology | Anti-Inflammatory Agents - pharmacology | Fruit - chemistry | Nitric Oxide - antagonists & inhibitors | Sulfonic Acids - analysis | Antioxidants - pharmacology | California | Biphenyl Compounds - analysis | Phenols - analysis | Animals | Benzothiazoles - analysis | Cyclooxygenase 2 - metabolism | Cyclooxygenase 2 Inhibitors - analysis | RAW 264.7 Cells | Mice | Nitric Oxide Synthase Type II - metabolism | Antioxidants | Flavonoids | Flavones | Anti-inflammatory drugs | Bioflavonoids | Citrus | Citrus fruits | COX-2 inhibitors | Crop yields | Nitric oxide | Gastrointestinal diseases | Biological response modifiers | Mitogens | Interferon gamma | Isoflavones | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 12/2009, Volume 107, Issue 1, pp. 28 - 33
...) including aspirin whereas COX-2 activity is preferentially blocked by COX-2 inhibitors called coxibs... 
Enzymes | Prostaglandins | Active sites | Cyclooxygenase inhibitors | Atoms | Dimers | Platelet aggregation | Platelets | Fatty acids | Monomers | Platelet | Prostaglandin | Arachidonic acid | Adrenic acid | Nonsteroidal antiinflammatory drugs | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Crystallography, X-Ray | Isoenzymes - chemistry | Cyclooxygenase 2 Inhibitors - chemistry | Protein Subunits - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Aspirin - metabolism | Isoenzymes - metabolism | Cyclooxygenase 1 - chemistry | Platelet Aggregation Inhibitors - pharmacology | Cyclooxygenase 2 Inhibitors - metabolism | Platelet Aggregation - drug effects | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Aspirin - pharmacology | Platelet Aggregation Inhibitors - metabolism | Catalytic Domain | Cyclooxygenase Inhibitors - metabolism | Cyclooxygenase 2 Inhibitors - pharmacology | Models, Molecular | Cyclooxygenase Inhibitors - chemistry | Cyclooxygenase Inhibitors - pharmacology | Animals | Dogs | Aspirin - chemistry | Protein Binding | Protein Conformation | Protein Subunits - chemistry | Cyclooxygenase 1 - metabolism | Aspirin | Usage | Physiological aspects | Cyclooxygenases | Genetic aspects | Research | Health aspects | Index Medicus | CATALYSIS | MONOMERS | THROMBOSIS | ARACHIDONIC ACID | PROCESSING | DIMERS | 60 APPLIED LIFE SCIENCES | ACETYLSALICYLIC ACID | PROSTAGLANDINS | IN VITRO | INFLAMMATION | TARGETS | SIDE EFFECTS | arachidonic acid | Biological Sciences | platelet | adrenic acid | prostaglandin | nonsteroidal antiinflammatory drugs
Journal Article
Journal Article