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European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2016, Volume 121, pp. 410 - 421
A new series of 2-substituted mercapto-4(3 )-quinazolinone were synthesized and assessed for anti-inflammatory and analgesic activities and inhibition of... 
Docking study | Synthesis | 2-Mercapto-4(3H)-quinazolinone | Cyclooxygenase-1/cyclooxygenase-2 inhibition assay | Anti-inflammatory activities | inhibition assay | Cyclooxygenase-1/cyclooxygenase-2 | SELECTIVE-INHIBITION | DESIGN | CHEMISTRY, MEDICINAL | CYCLOOXYGENASE-2 | ANALOGS | ANTITUMOR-ACTIVITY | DRUGS | BIOLOGICAL EVALUATION | DERIVATIVES | PROSTAGLANDIN SYNTHESIS | QUINAZOLINES | Analgesics - pharmacology | Analgesics - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Cyclooxygenase 2 Inhibitors - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Analgesics - chemical synthesis | Cyclooxygenase 1 - chemistry | Cyclooxygenase 2 Inhibitors - metabolism | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Quinazolinones - pharmacology | Cyclooxygenase 2 Inhibitors - chemical synthesis | Chemistry Techniques, Synthetic | Cyclooxygenase 2 Inhibitors - pharmacology | Cyclooxygenase 2 - chemistry | Quinazolinones - chemical synthesis | Animals | Analgesics - chemistry | Cyclooxygenase 2 - metabolism | Protein Conformation | Mice | Molecular Docking Simulation | Quinazolinones - chemistry | Cyclooxygenase 1 - metabolism | Quinazolinones - metabolism | Drugstores | COX-2 inhibitors | Pharmacy | Diclofenac | Index Medicus
Journal Article
Journal Article
Inflammation Research, ISSN 1023-3830, 02/1998, Volume 47, Issue 2, pp. 79 - 85
Journal Article
Journal Article
Chemical & Pharmaceutical Bulletin, ISSN 0009-2363, 2009, Volume 57, Issue 6, pp. 597 - 599
One new guaiane-type sesquiterpene glycoside, 2'-O-E-caffeoyl-8α-hydroxy-11α,13-dihydro-3β-O-β-D-glucozaluzanin C (1), was isolated from the whole herb of... 
Journal Article
Chemical & Pharmaceutical Bulletin, ISSN 0009-2363, 2007, Volume 55, Issue 1, pp. 64 - 71
Curcumin, a major yellow pigment and active component of turmeric, has been shown to possess anti-inflammatory and anti-cancer activities. Recent studies have... 
Journal Article
北関東医学, ISSN 1343-2826, 2007, Volume 57, Issue 1, pp. 43 - 48
【目 的】 術後疼痛管理において先制鎮痛の有用性が注目されるようになってきた. 今回, 下顎埋伏智歯抜歯後疼痛に対し, 作用機序の異なる非ステロイド性消炎鎮痛薬による先制鎮痛効果について検討した. 【対象と方法】 下顎埋伏智歯抜歯症例33例に対し, 無作為に抜歯開始1時間前にZaltoprofen... 
ブラジキニン | 先制鎮痛 | 下顎埋伏智歯抜歯 | 非ステロイド性消炎鎮痛薬 | シクロオキシゲナーゼ-2
Journal Article
Iyakuhin Johogaku = Japanese Journal of Drug Informatics, ISSN 1345-1464, 01/2017, Volume 19, Issue 3, p. 127
Objective: Gastrointestinal tract injury associated with non-steroidal anti-inflammatory drugs (NSAIDs) remains a clinically significant problem. Therefore,... 
Meloxicam | Drugs | Aspirin | Antiinflammatory agents | Health risks | Data processing | Risk | Gastrointestinal tract | Pharmacology | Inflammation | Nonsteroidal antiinflammatory drugs | Cyclooxygenase-1 | Cyclooxygenase-2 | Signal detection | Injuries | Injury analysis
Journal Article
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