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The New England Journal of Medicine, ISSN 0028-4793, 12/2007, Volume 357, Issue 25, pp. 2562 - 2575
This study examines the toxicity of immunosuppressive regimens in renal-transplant recipients. A regimen containing mycophenolate mofetil, daclizumab, low-dose... 
MULTICENTER TRIAL | MEDICINE, GENERAL & INTERNAL | CYCLOSPORINE MICROEMULSION | EFFICACY | KIDNEY-TRANSPLANTATION | IMMUNOSUPPRESSION | ALLOGRAFT RECIPIENTS | TACROLIMUS | MYCOPHENOLATE-MOFETIL | SIROLIMUS | NEPHROTOXICITY | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Adrenal Cortex Hormones - therapeutic use | Enzyme Inhibitors - administration & dosage | Antibodies, Monoclonal, Humanized | Calcineurin Inhibitors | Treatment Failure | Adult | Diabetes Mellitus - etiology | Female | Drug Therapy, Combination | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Sirolimus - adverse effects | Tacrolimus - administration & dosage | Prednisone - administration & dosage | Glomerular Filtration Rate | Graft Rejection - prevention & control | Kaplan-Meier Estimate | Kidney Transplantation | Immunoglobulin G - administration & dosage | Opportunistic Infections | Sirolimus - administration & dosage | Mycophenolic Acid - analogs & derivatives | Antibodies, Monoclonal - administration & dosage | Cyclosporine - administration & dosage | Immunosuppressive Agents - adverse effects | Aged | Adrenal Cortex Hormones - administration & dosage | Transplantation | Corticosteroids | Kidneys | Research | Health aspects | Immunosuppressive agents | Medical research | Immunology | Inhibitor drugs | Transplants & implants | Toxicity | Index Medicus | Abridged Index Medicus | Inhibidors enzimàtics | Posologia | Ús terapèutic | Corticosteroides | Rebuig (Biologia) | Posology | Therapeutic use | Immunosupressive agents | Graft rejection | Trasplantament renal | Enzyme inhibitors | Adrenocortical hormones | Immunosupressors | Kidney transplantation | Tacrolimus: administration & dosage | Medical and Health Sciences | Graft Rejection: prevention & control | Immunoglobulin G: administration & dosage | Medicin och hälsovetenskap | Mycophenolic Acid: administration & dosage | Antibodies | Klinisk medicin | Monoclonal: administration & dosage | Prednisone: administration & dosage | Adrenal Cortex Hormones: administration & dosage | Immunosuppressive Agents: administration & dosage | Mycophenolic Acid: analogs & derivatives | Sirolimus: administration & dosage | Cyclosporine: administration & dosage | Calcineurin: antagonists & inhibitors | Diabetes Mellitus: etiology | Urologi och njurmedicin | Sirolimus: adverse effects | Adrenal Cortex Hormones: therapeutic use | Enzyme Inhibitors: administration & dosage | Immunosuppressive Agents: adverse effects | Clinical Medicine | Immunosuppressive Agents: therapeutic use | Urology and Nephrology
Journal Article
The American Journal of Cardiology, ISSN 0002-9149, 2004, Volume 94, Issue 9, pp. 1140 - 1146
Three-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors (statins) are first-line treatments for hypercholesterolemia. Although exceedingly well... 
CLARITHROMYCIN | INDUCED RHABDOMYOLYSIS | LOVASTATIN | CARDIAC & CARDIOVASCULAR SYSTEMS | CONCOMITANT USE | ERYTHROMYCIN | FATAL RHABDOMYOLYSIS | ITRACONAZOLE | ROSUVASTATIN | DRUG-INTERACTION | CYCLOSPORINE | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Pyrroles - pharmacokinetics | Cytochrome P-450 Enzyme Inhibitors | Cytochrome P-450 Enzyme System - administration & dosage | Area Under Curve | Heptanoic Acids - pharmacokinetics | Humans | Middle Aged | Mibefradil - pharmacokinetics | Male | Protein Synthesis Inhibitors - administration & dosage | Verapamil - administration & dosage | Dose-Response Relationship, Drug | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Antiprotozoal Agents - pharmacokinetics | Drug Interactions | Itraconazole - pharmacokinetics | Pyrroles - administration & dosage | Clarithromycin - pharmacokinetics | Mibefradil - administration & dosage | Clarithromycin - administration & dosage | Heptanoic Acids - administration & dosage | Adult | Female | Itraconazole - administration & dosage | Drug Therapy, Combination | Double-Blind Method | Simvastatin - administration & dosage | Verapamil - pharmacokinetics | Biomarkers - blood | Simvastatin - pharmacokinetics | Protein Synthesis Inhibitors - pharmacokinetics | Atorvastatin Calcium | Anticholesteremic Agents - pharmacokinetics | Pravastatin - administration & dosage | Anticholesteremic Agents - administration & dosage | Adolescent | Antiprotozoal Agents - administration & dosage | Calcium Channel Blockers - administration & dosage | Creatine Kinase - drug effects | Calcium Channel Blockers - pharmacokinetics | Pravastatin - pharmacokinetics | Index Medicus | Abridged Index Medicus
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 12/2016, Volume 82, Issue 6, pp. 1591 - 1600
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 05/2015, Volume 15, Issue 5, pp. 1313 - 1322
The authors describe the drug–drug interaction profile of the he patitis C direct‐acting antiviral agents ABT‐450, ombitasvir, and dasabuvir with cyclosporine... 
infectious disease | clinical research/practice | pharmacology | calcineurin inhibitor: cyclosporine A (CsA) | pharmacokinetics/pharmacodynamics | immunosuppressant | infection and infectious agents | calcineurin inhibitor: tacrolimus | liver transplantation/hepatology | viral: hepatitis C | SURGERY | ABT-450/R-OMBITASVIR | LIVER-TRANSPLANTATION | EFFICACY | DRUG-INTERACTIONS | TRANSPORTERS | INFECTION | HCV | RIBAVIRIN | INHIBITOR | HEPATITIS-C | TRANSPLANTATION | Antiviral Agents - pharmacokinetics | Hepatitis C - drug therapy | Area Under Curve | Humans | Middle Aged | Male | Anilides - pharmacokinetics | Carbamates - administration & dosage | Healthy Volunteers | Carbamates - pharmacokinetics | Young Adult | Uracil - administration & dosage | Cyclosporine - pharmacokinetics | Adult | Female | Tacrolimus - administration & dosage | Hepacivirus - drug effects | Drug Administration Schedule | Macrocyclic Compounds - pharmacokinetics | Tacrolimus - pharmacokinetics | Antiviral Agents - administration & dosage | Sulfonamides - pharmacokinetics | Anilides - administration & dosage | Adolescent | Cyclosporine - administration & dosage | Macrocyclic Compounds - administration & dosage | Uracil - pharmacokinetics | Sulfonamides - administration & dosage | Uracil - analogs & derivatives | Dosage and administration | Liver diseases | Drug therapy, Combination | Tacrolimus | Hepatitis C virus | Hepatitis C | Hepatitis | Medical research | Drug dosages | Index Medicus | practice | pharmacodynamics | hepatology | clinical research | pharmacokinetics | Original | liver transplantation
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 02/2017, Volume 518, Issue 1-2, pp. 193 - 202
In this study, a new type of mixed micelles was developed using Soluplus (SOL) and Pluronic P105 (P105) for the encapsulation of Oridonin (ORN).... 
Soluplus | Bioavailability | Micelles | Oridonin | Pluronic® P105 | Pluronic | P105 | SUPERSATURATED POLYMERIC MICELLES | Pluronic (R) P105 | DRUG-RELEASE | OVARIAN-CANCER | CYCLODEXTRIN INCLUSION COMPLEX | CYCLOSPORINE-A DELIVERY | Soluplus (R) | TUMOR SPHEROIDS | BETA-CYCLODEXTRIN | PHARMACOLOGY & PHARMACY | IN-VIVO EVALUATION | HOT-MELT EXTRUSION | SUSTAINED-RELEASE | Humans | Spheroids, Cellular - pathology | Drug Carriers - administration & dosage | Biological Availability | Male | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Polyvinyls - pharmacokinetics | Spheroids, Cellular - drug effects | Antineoplastic Agents, Phytogenic - pharmacokinetics | Poloxamer - administration & dosage | Diterpenes, Kaurane - chemistry | Poloxamer - chemistry | Cell Survival - drug effects | Administration, Oral | Poloxamer - pharmacokinetics | Polyethylene Glycols - pharmacokinetics | Antineoplastic Agents, Phytogenic - chemistry | Rats, Sprague-Dawley | Polyethylene Glycols - administration & dosage | Particle Size | Animals | Polyvinyls - administration & dosage | Diterpenes, Kaurane - pharmacokinetics | Mice, Nude | Cell Line, Tumor | Drug Liberation | Drug Carriers - pharmacokinetics | Diterpenes, Kaurane - administration & dosage | Polyvinyls - chemistry | Index Medicus
Journal Article
Liver Transplantation, ISSN 1527-6465, 07/2013, Volume 19, Issue 7, pp. 690 - 700
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 04/2018, Volume 20, Issue 1, pp. 65 - 65
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 05/2018, Volume 58, Issue 5, pp. 666 - 673
Elbasvir (EBR)/grazoprevir (GZR) may be coadministered with immunosuppressant drugs in posttransplant people who are infected with hepatitis C virus. The aim... 
cyclosporine | drug‐drug interactions | tacrolimus | pharmacokinetics | grazoprevir | mycophenolate mofetil | prednisone | elbasvir | drug-drug interactions | EFFICACY | GRAZOPREVIR MK-5172 | SAFETY | COMBINATION THERAPY | LABEL PHASE-2 TRIAL | RIBAVIRIN | HEPATITIS-C VIRUS | GENOTYPE 1 INFECTION | PHARMACOLOGY & PHARMACY | ELBASVIR MK-8742 | TREATMENT-NAIVE PATIENTS | Quinoxalines - adverse effects | Antiviral Agents - pharmacokinetics | Area Under Curve | Humans | Immunosuppressive Agents - pharmacokinetics | Middle Aged | Imidazoles - administration & dosage | Benzofurans - administration & dosage | Male | Imidazoles - pharmacokinetics | Benzofurans - pharmacokinetics | Young Adult | Drug Interactions | Cyclosporine - pharmacokinetics | Adult | Female | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Tacrolimus - administration & dosage | Prednisone - administration & dosage | Quinoxalines - pharmacokinetics | Prednisone - adverse effects | Quinoxalines - administration & dosage | Administration, Oral | Imidazoles - adverse effects | Mycophenolic Acid - pharmacokinetics | Tacrolimus - pharmacokinetics | Tacrolimus - adverse effects | Antiviral Agents - administration & dosage | Benzofurans - adverse effects | Mycophenolic Acid - adverse effects | Antiviral Agents - adverse effects | Cyclosporine - adverse effects | Cyclosporine - administration & dosage | Prednisone - pharmacokinetics | Immunosuppressive Agents - adverse effects | Drug Combinations | Drugs | Mycophenolic acid | Cyclosporins | Transaminase | Viruses | Prednisone | Pharmacology | Hepatitis | Tacrolimus | Mycophenolate mofetil | Hepatitis C virus | Pharmacokinetics | Hepatitis C | Drug dosages | Prednisolone | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 2011, Volume 118, Issue 9, pp. 2413 - 2419
To improve the outcome of allogeneic stem cell transplantation (allo-SCT) in multiple myeloma as part of first-line treatment, we prospectively investigated... 
CRITERIA | DEXAMETHASONE | AGENTS | HEMATOLOGY | Whole-Body Irradiation | Cyclophosphamide - administration & dosage | Graft vs Host Disease - epidemiology | Prospective Studies | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Transplantation, Autologous | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Melphalan - therapeutic use | Cyclophosphamide - therapeutic use | Transplantation, Homologous | Feasibility Studies | Thalidomide - analogs & derivatives | Multiple Myeloma - drug therapy | Antineoplastic Agents - adverse effects | Adult | Female | Hematopoietic Stem Cell Mobilization | Transplantation Conditioning - methods | Mycophenolic Acid - administration & dosage | Graft vs Host Disease - etiology | Multiple Myeloma - surgery | Immunosuppressive Agents - administration & dosage | Thalidomide - adverse effects | Drug Eruptions - etiology | Hematologic Diseases - chemically induced | Acute Disease | Immunologic Factors - administration & dosage | Combined Modality Therapy | Thalidomide - administration & dosage | Remission Induction | Cyclosporine - therapeutic use | Disease-Free Survival | Melphalan - administration & dosage | Mycophenolic Acid - analogs & derivatives | Mycophenolic Acid - therapeutic use | Cyclosporine - administration & dosage | Lymphocyte Count | Aged | Immunologic Factors - adverse effects | Hematopoietic Stem Cell Transplantation - methods | Thalidomide - therapeutic use | Immunologic Factors - therapeutic use | Index Medicus | Abridged Index Medicus
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 2012, Volume 80, Issue 1, pp. 54 - 60
Journal Article
Journal Article
The Lancet, ISSN 0140-6736, 2016, Volume 387, Issue 10019, pp. 671 - 678
Journal Article