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Cancer Treatment Reviews, ISSN 0305-7372, 2016, Volume 44, pp. 51 - 60
Highlights • Role of immune checkpoint inhibition in the management of key malignancies. • Description of rates of immune-related adverse events and timing of... 
Hematology, Oncology and Palliative Medicine | Pembrolizumab | Immune-related adverse events | Renal cancer | Ipilimumab | Nivolumab | Lung cancer | Melanoma | Immune-checkpoint inhibitors | OPEN-LABEL | SINGLE-ARM | ANTI-CTLA-4 ANTIBODY | METASTATIC MELANOMA | ONCOLOGY | ADVANCED MELANOMA | LONG-TERM SAFETY | MALIGNANT MESOTHELIOMA | ENTERIC NEUROPATHY | ADVERSE EVENTS | IPILIMUMAB RETREATMENT | Lung Neoplasms - drug therapy | Skin Neoplasms - drug therapy | Humans | Immunosuppressive Agents - therapeutic use | Antibodies, Monoclonal - adverse effects | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Adrenal Cortex Hormones - therapeutic use | Diarrhea - chemically induced | Infliximab - therapeutic use | Drug Eruptions - drug therapy | Antineoplastic Agents - adverse effects | Colitis - chemically induced | Antilymphocyte Serum - therapeutic use | Colitis - drug therapy | Carcinoma, Renal Cell - drug therapy | Chemical and Drug Induced Liver Injury - etiology | Pituitary Diseases - chemically induced | Pituitary Diseases - drug therapy | Antibodies, Monoclonal, Humanized - adverse effects | Drug Eruptions - etiology | Neoplasms - drug therapy | Cyclosporine - therapeutic use | Tacrolimus - therapeutic use | Mycophenolic Acid - analogs & derivatives | Mycophenolic Acid - therapeutic use | Melanoma - drug therapy | Chemical and Drug Induced Liver Injury - drug therapy | Diarrhea - drug therapy | CTLA-4 Antigen - antagonists & inhibitors | Kidney Neoplasms - drug therapy | Thyroiditis - drug therapy | Thyroiditis - chemically induced | Index Medicus
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 11/2017, Volume 17, Issue 11, pp. 2829 - 2840
Journal Article
THERAPEUTIC DRUG MONITORING, ISSN 0163-4356, 04/2019, Volume 41, Issue 2, pp. 213 - 226
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 10/2012, Volume 264, Issue 2, pp. 192 - 201
Oxidative stress and mitochondrial permeability transition (MPT) are important mechanisms in acetaminophen (APAP) toxicity. The MPT inhibitor trifluoperazine... 
Mitochondrial permeability transition | Mitochondria | Phospholipase A2 | Acetaminophen | Toxicity | Phospholipase A | Immunohistochemistry | Tumor Necrosis Factor-alpha - metabolism | Trifluoperazine - pharmacology | Mitochondria, Liver - metabolism | Hepatocytes - pathology | Male | Hepatocytes - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Analgesics, Non-Narcotic - toxicity | Proliferating Cell Nuclear Antigen - biosynthesis | Hypoxia-Inducible Factor 1, alpha Subunit - biosynthesis | Chemical and Drug Induced Liver Injury - pathology | Hepatocytes - drug effects | Mitochondria, Liver - pathology | Cytokines - metabolism | Acetaminophen - toxicity | Permeability | Dinoprostone - metabolism | Mitochondria, Liver - drug effects | Animals | Signal Transduction - drug effects | Prostaglandin-Endoperoxide Synthases - metabolism | Receptors, Phospholipase A2 - antagonists & inhibitors | Indicators and Reagents | Mice | Receptors, Phospholipase A2 - metabolism | Liver Regeneration - drug effects | Index Medicus | Oxidative stress | Trifluoperazine | Hypoxia-inducible factor 1 alpha | Liver | Prostaglandin E2 | Protein turnover | Protein adducts | Hepatocytes | Proliferating cell nuclear antigen | Glutathione | OXIDATION | PERMEABILITY | MITOCHONDRIA | ANTIGENS | TOXICITY | 60 APPLIED LIFE SCIENCES | GROWTH FACTORS | METABOLISM | PROSTAGLANDINS | ALANINES | ANOXIA | GLUTATHIONE | ACTIVITY LEVELS | LIVER | LIVER CELLS | MICE | CYCLOSPORINE
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2017, Volume 114, Issue 52, pp. E11313 - E11322
Calcineurin is an essential Ca2+-dependent phosphatase. Increased calcineurin activity is associated with alpha-synuclein (alpha-syn) toxicity, a protein... 
Parkinson's Disease | Tacrolimus | Calcineurin | α-synuclein | FKBP12 | NERVOUS-SYSTEM | MULTIDISCIPLINARY SCIENCES | MODEL | calcineurin | alpha-synuclein | SACCHAROMYCES-CEREVISIAE | MIDBRAIN DOPAMINERGIC-NEURONS | FK506 BINDING-PROTEINS | DEGENERATION | CYCLOSPORINE-A | NEUROTROPHIC ACTIONS | BRAIN | PARKINSONS-DISEASE | Biological Sciences | PNAS Plus | Parkinson’s Disease
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 12/2011, Volume 11, Issue 12, pp. 2549 - 2550
No histological lesions specific for renal calcineurin inhibitor toxicity exist, and this is a critical issue influencing the interpretation of all literature... 
Arterioles - pathology | Cyclosporine - adverse effects | Humans | Kidney Diseases - diagnosis | Biomarkers - analysis | Kidney Diseases - chemically induced | Female | Immunosuppressive Agents - adverse effects | Male | Kidney Transplantation | Index Medicus
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 12/2015, Volume 30, Issue 1, pp. 79 - 94
Journal Article
Journal Article