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Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 9, pp. 4356 - 4373
The mitochondrial permeability transition pore is a recognized drug target for neurodegenerative conditions such as multiple sclerosis and for... 
HUMAN CYCLOPHILIN-D | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | AXONAL DEGENERATION | CYCLOSPORINE-A | TRAUMATIC BRAIN-INJURY | ATP SYNTHASE | TRIPHENYLPHOSPHONIUM CATIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | LENTIVIRAL VECTOR | P-GLYCOPROTEIN | Mitochondrial Membrane Transport Proteins - antagonists & inhibitors | Humans | Cerebral Cortex - pathology | Male | Cyclophilins - metabolism | Multiple Sclerosis - prevention & control | Cyclosporins - pharmacology | Mitochondrial Membrane Transport Proteins - genetics | Cyclophilins - antagonists & inhibitors | Neuroprotective Agents - pharmacology | Liver - drug effects | Cyclosporins - therapeutic use | T-Lymphocytes - drug effects | Neurons - metabolism | Cerebral Cortex - drug effects | Neuroprotective Agents - adverse effects | Quinolinium Compounds - therapeutic use | Quinolinium Compounds - adverse effects | Cyclosporins - chemical synthesis | Mitochondrial Membrane Transport Proteins - metabolism | Liver - metabolism | Recombinant Proteins - chemistry | Cyclophilins - genetics | Random Allocation | Mice, Knockout | Cerebral Cortex - immunology | Peptides, Cyclic - therapeutic use | Mutation | Peptides, Cyclic - adverse effects | Neuroprotective Agents - therapeutic use | Neurons - pathology | Peptides, Cyclic - pharmacology | Cerebral Cortex - metabolism | Quinolinium Compounds - pharmacology | T-Lymphocytes - pathology | Neurons - drug effects | Multiple Sclerosis - metabolism | Recombinant Proteins - metabolism | Cells, Cultured | Cyclosporins - adverse effects | Neurons - immunology | Mice, Inbred Strains | Hep G2 Cells | Animals | Peptides, Cyclic - chemical synthesis | Quinolinium Compounds - chemical synthesis | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Cell Proliferation - drug effects | Amino Acid Substitution | Index Medicus | X-ray crystallography | Molecular Bases of Disease | mitochondrial permeability transition (MPT) | cyclophilin D | neurodegenerative disease | multiple sclerosis | neurodegeneration | EAE | cyclosporin | mitochondrial targeting
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2010, Volume 54, Issue 2, pp. 660 - 672
Journal Article
Scientific reports, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 5590 - 1
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. 
Cyclosporins | Chitosan
Journal Article
Journal Article
American Journal of Reproductive Immunology, ISSN 1046-7408, 06/2018, Volume 80, Issue S1, pp. 103 - 103
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 57, Issue 1, pp. 47 - 54
Background & Aims SCY-635 is a non-immunosuppressive analog of cyclosporin A that inhibits cyclophilins A and B and hepatitis C virus (HCV) replication in... 
Gastroenterology and Hepatology | SCY-635 | IL28B | Chronic hepatitis C | 2′5′OAS-1 | Cyclophilin inhibitor | Interferon λ | Interferon α | 2 ' 5 ' OAS-1 | IN-VITRO | Interferon lambda | VIRUS-RNA REPLICATION | Interferon alpha | GASTROENTEROLOGY & HEPATOLOGY | HEPATITIS-C | CYCLOSPORINE | Antiviral Agents - pharmacokinetics | Humans | Middle Aged | Cyclosporins - administration & dosage | Hepacivirus - genetics | Male | Liver Neoplasms | Cyclosporins - pharmacokinetics | Dose-Response Relationship, Drug | Cyclophilins - antagonists & inhibitors | Interleukins - genetics | Adult | Female | Hepacivirus - drug effects | Cyclosporins - adverse effects | Genotype | Treatment Outcome | Hepatitis C, Chronic - drug therapy | Antiviral Agents - administration & dosage | Cyclophilin A - antagonists & inhibitors | Antiviral Agents - adverse effects | Interferon-alpha - blood | Hepatitis C, Chronic - immunology | Cell Line, Tumor | Interferon-beta - blood | Hepacivirus - growth & development | Aged | Carcinoma, Hepatocellular | Interferon-gamma - blood | Antiviral agents | Care and treatment | Genes | Immunodeficiency | Aspartate | Cyclosporine | Biological response modifiers | HIV (Viruses) | Virus diseases | Complications and side effects | Hepatitis | Ligases | Interferon beta | Genetic aspects | Interferon | Hepatitis C virus | Hepatitis C | Health aspects | Index Medicus
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2013, Volume 451, Issue 2, pp. 245 - 255
Genetic variation plays a major role in drug response variability. CsA (cyclosporin A), a widely used immunosuppressive agent, is a specific antagonist for... 
Formyl peptide receptor 1 (FPR1) | Receptor affinity | Cyclosporin | Single nucleotide polymorphism | Haplotype | Pharmacogenomics | AGGRESSIVE PERIODONTITIS | DOMAIN | haplotype | ANALOG | single nucleotide polymorphism | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOXORUBICIN | GP41 | formyl peptide receptor 1 (FPR1) | receptor affinity | COMBINATION | RESPONSES | pharmacogenomics | CHEMOTACTIC AGONIST | INHIBITION | cyclosporin | SINGLE-NUCLEOTIDE POLYMORPHISMS | Haplotypes | Cricetinae | Pharmacogenetics | Cricetulus | Calcium - metabolism | Cyclosporine - pharmacology | Humans | Male | Chemotaxis - drug effects | Cyclosporins - metabolism | Cyclosporins - pharmacology | Asian Continental Ancestry Group | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Receptors, Formyl Peptide - metabolism | N-Formylmethionine Leucyl-Phenylalanine - pharmacology | Female | Polymorphism, Single Nucleotide | CHO Cells - drug effects | Receptors, Formyl Peptide - genetics | Amino Acid Substitution | CsH, cyclosporin H | LD, linkage disequilibrium | CsA, cyclosporin A | fMLF, N-formyl-methionyl-leucyl-phenylalanine | FPR, formyl peptide receptor | MAF, minor allele frequency | ORF, open reading frame | ERK, extracellular-signal-regulated kinase | fNLFNYK, N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys | CHO, Chinese-hamster ovary | SNP, single nucleotide polymorphism | AM, Fluo-4 acetoxymethyl ester | Fluo-4 | HBSS, Hanks balanced saline solution | MAPK, mitogen-activated protein kinase
Journal Article
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 02/2007, Volume 81, Issue 2, pp. 213 - 221
Exploratory analyses of data pertaining to pharmacokinetic, pharmacodynamic, and disease progression are often referred to as the pharmacometrics (PM)... 
PHARMACOLOGY & PHARMACY | EXPERIENCE | Drug Evaluation - methods | Lipoproteins - therapeutic use | Quinoxalines - adverse effects | Risk Assessment - methods | United States | Benzazepines - adverse effects | Humans | United States Food and Drug Administration - standards | Varenicline | Cyclosporins - administration & dosage | Data Collection | Peptides, Cyclic - administration & dosage | United States Food and Drug Administration - legislation & jurisprudence | Drug Labeling - legislation & jurisprudence | Cyclosporins - therapeutic use | Investigational New Drug Application - legislation & jurisprudence | Everolimus | Sirolimus - adverse effects | Lipoproteins - adverse effects | Quinoxalines - therapeutic use | Sirolimus - analogs & derivatives | Sirolimus - therapeutic use | Drug Administration Schedule | Peer Review | Quinoxalines - administration & dosage | Cyclosporins - adverse effects | Decision Support Techniques | Pharmacology, Clinical | Treatment Outcome | Disease Progression | Drug Approval - legislation & jurisprudence | Sirolimus - administration & dosage | Lipoproteins - administration & dosage | Benzazepines - therapeutic use | Echinocandins | Investigational New Drug Application - statistics & numerical data | Peptides, Cyclic - therapeutic use | Benzazepines - administration & dosage | Clinical Trials as Topic - methods | Pharmacokinetics | Lipopeptides | Peptides, Cyclic - adverse effects
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2016, Volume 36, Issue 23, pp. 6269 - 6286
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 06/2015, Volume 26, Issue 6, pp. 1443 - 1448
Journal Article