X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (13651) 13651
Publication (1668) 1668
Newsletter (339) 339
Book Review (143) 143
Book Chapter (83) 83
Conference Proceeding (25) 25
Newspaper Article (13) 13
Magazine Article (12) 12
Book / eBook (7) 7
Dissertation (5) 5
Government Document (3) 3
Reference (3) 3
Transcript (2) 2
Paper (1) 1
Presentation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (7602) 7602
humans (6798) 6798
animals (6567) 6567
cysteine (5688) 5688
male (3074) 3074
mice (2652) 2652
biochemistry & molecular biology (2579) 2579
pharmacology & pharmacy (2336) 2336
female (2282) 2282
oxidative stress (2119) 2119
proteins (2113) 2113
analysis (1979) 1979
rats (1942) 1942
cystine (1711) 1711
apoptosis (1692) 1692
cancer (1334) 1334
article (1251) 1251
glutathione (1206) 1206
expression (1192) 1192
cell biology (1175) 1175
research (1162) 1162
enzymes (1129) 1129
antioxidants (1102) 1102
thiols (1046) 1046
physiological aspects (1035) 1035
activation (962) 962
toxicology (952) 952
health aspects (932) 932
cell line, tumor (931) 931
research article (910) 910
oncology (905) 905
medicine (883) 883
adult (872) 872
proteases (868) 868
multidisciplinary sciences (857) 857
neurosciences (855) 855
gene expression (842) 842
peptides (833) 833
cysteine - metabolism (830) 830
in-vitro (829) 829
cysteine proteinase inhibitors - pharmacology (820) 820
immunology (818) 818
middle aged (812) 812
amino acid sequence (804) 804
cells (792) 792
cysteine - analogs & derivatives (786) 786
apoptosis - drug effects (785) 785
cysteine - chemistry (785) 785
cysteine endopeptidases - metabolism (783) 783
cells, cultured (775) 775
inflammation (729) 729
chemistry, medicinal (723) 723
dose-response relationship, drug (705) 705
disease models, animal (698) 698
biochemistry (696) 696
reactive oxygen species - metabolism (682) 682
inhibition (677) 677
molecular sequence data (676) 676
amino acids (666) 666
glutathione - metabolism (665) 665
signal transduction (643) 643
cell line (638) 638
science (638) 638
biology (637) 637
protein binding (633) 633
rats, sprague-dawley (622) 622
metabolism (604) 604
oxidation-reduction (597) 597
acetylcysteine (594) 594
in-vivo (594) 594
models, molecular (594) 594
rodents (583) 583
protein (570) 570
mice, inbred c57bl (566) 566
acetylcysteine - pharmacology (562) 562
oxidative stress - drug effects (552) 552
time factors (552) 552
biophysics (542) 542
cysteine - pharmacology (539) 539
cysteine - therapeutic use (534) 534
care and treatment (524) 524
medicine, research & experimental (522) 522
aged (512) 512
cell survival - drug effects (506) 506
identification (496) 496
chemistry, multidisciplinary (490) 490
reactive oxygen species (485) 485
mutation (483) 483
toxicity (482) 482
mass spectrometry (478) 478
microbiology (478) 478
chemistry (474) 474
n-acetylcysteine (469) 469
endocrinology & metabolism (467) 467
life sciences (467) 467
genetic aspects (452) 452
acetylcysteine - therapeutic use (441) 441
rats, wistar (441) 441
disease (440) 440
nf-kappa-b (439) 439
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (13746) 13746
German (105) 105
Japanese (64) 64
Russian (49) 49
French (25) 25
Italian (23) 23
Chinese (18) 18
Spanish (17) 17
Polish (5) 5
Portuguese (3) 3
Arabic (2) 2
Czech (2) 2
Hungarian (2) 2
Romanian (2) 2
Swedish (2) 2
Bulgarian (1) 1
Dutch (1) 1
Serbian (1) 1
Slovak (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Drug Resistance Updates, ISSN 1368-7646, 2007, Volume 10, Issue 6, pp. 218 - 234
Abstract The increased incidence of malignant melanoma in the last decades, its high mortality and pronounced therapy resistance pose an enormous challenge.... 
Infectious Disease | Hematology, Oncology and Palliative Medicine | NF-κB | CD95 | TRAIL | PKB/Akt | PI3 kinase | Death ligands | Sorafenib | Melanoma | Bcl-2 proteins | B-Raf | MAPK | Apoptosis | CUTANEOUS MALIGNANT-MELANOMA | bcl-2 proteins | ACTIVATED PROTEIN-KINASE | sorafenib | melanoma | apoptosis | FACTOR-KAPPA-B | CHEMOSENSITIZES HUMAN-MELANOMA | BH3 MIMETIC ABT-737 | PHASE-II TRIAL | NF-kappa B | B-raf | MANTLE CELL LYMPHOMA | death ligands | PHARMACOLOGY & PHARMACY | TRAIL-INDUCED APOPTOSIS | CYTOCHROME-C RELEASE | BCL-2 FAMILY-MEMBERS | Apoptosis - drug effects | Humans | Gene Expression Regulation, Neoplastic | Melanoma - enzymology | Apoptosis - genetics | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Intracellular Signaling Peptides and Proteins - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Receptors, Death Domain - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspases - metabolism | Melanoma - genetics | Antineoplastic Agents - pharmacology | Melanoma - metabolism | Cell Survival - drug effects | Cysteine Proteinase Inhibitors - therapeutic use | Receptors, Death Domain - agonists | Tumor Suppressor Protein p53 - metabolism | Signal Transduction - genetics | Melanoma - pathology | Animals | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Melanoma - drug therapy | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Mutation | Development and progression | Care and treatment | Health aspects | Cancer
Journal Article
Science, ISSN 0036-8075, 04/2018, Volume 360, Issue 6387, pp. 449 - 453
Activated immune cells undergo a metabolic switch to aerobic glycolysis akin to the Warburg effect, thereby presenting a potential therapeutic target in... 
INACTIVATION | ACTIVATION | MULTIPLE-SCLEROSIS | PATHWAY | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | EFFECTOR FUNCTION | SUBSETS | T-CELLS | ACID ESTERS | Myeloid Cells - enzymology | Succinates - chemistry | Autoimmune Diseases - enzymology | Humans | Immunosuppressive Agents - therapeutic use | Mice, Inbred C57BL | Glycolysis - drug effects | Citric Acid Cycle | Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) - metabolism | Animals | Lymphocytes - immunology | Dimethyl Fumarate - pharmacology | Dimethyl Fumarate - therapeutic use | Myeloid Cells - immunology | Lymphocytes - drug effects | Lymphocytes - enzymology | Myeloid Cells - drug effects | Cysteine - metabolism | Mice | Immunosuppressive Agents - pharmacology | Autoimmune Diseases - drug therapy | Autoimmunity - drug effects | Biological research | Glyceraldehyde 3-phosphate dehydrogenase | Fumaric acid | Physiological aspects | Glycolysis | Research | Biology, Experimental | Dimethyl | Tricarboxylic acid cycle | Enzymes | Cysteine | Multiple sclerosis | Lymphoid cells | Immune response | Psoriasis | Immunomodulation | Therapeutic applications | Glyceraldehyde | Inflammation | Glyceraldehyde 3-phosphate | Metabolism | Immunity | Krebs cycle | Glyceraldehyde-3-phosphate dehydrogenase | Catalysis | Autoimmune diseases | Immune system
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 05/2013, Volume 18, Issue 5, pp. 557 - 567
Perturbation of Disrupted-In-Schizophrenia-1 (DISC1) and D-serine/NMDA receptor hypofunction have both been implicated in the pathophysiology of schizophrenia... 
serine racemase | MK-801 | D-serine | astrocytes | schizophrenia | DISC1 | MOUSE-BRAIN | PSYCHIATRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISC1 PROTEIN | D-ASPARTATE RECEPTOR | NEUROSCIENCES | TARGETED DISRUPTION | GLUTAMATE NEUROTRANSMISSION | MICE | MENTAL-ILLNESS | RAT-BRAIN | GLIA | INDUCIBLE EXPRESSION | Neuroprotective Agents - therapeutic use | Glial Fibrillary Acidic Protein - genetics | Humans | Nerve Tissue Proteins - deficiency | Male | Reflex, Startle - genetics | Schizophrenia - pathology | Dopamine Agents - therapeutic use | Glial Fibrillary Acidic Protein - metabolism | Brain - metabolism | Dose-Response Relationship, Drug | Exploratory Behavior - physiology | Racemases and Epimerases - metabolism | Schizophrenia - genetics | Transfection | Schizophrenia - physiopathology | Protein Binding - drug effects | Acoustic Stimulation - adverse effects | Dizocilpine Maleate - therapeutic use | Female | Disease Models, Animal | Inhibition (Psychology) | Astrocytes - drug effects | Amphetamine - therapeutic use | Mice, Inbred C57BL | Mice, Transgenic | Mutation - genetics | Cycloheximide - pharmacology | Brain - drug effects | Animals | Leupeptins | Maze Learning | Analysis of Variance | Serine - pharmacology | Cysteine Proteinase Inhibitors - pharmacology | Mice | Schizophrenia - drug therapy | Cell Line, Transformed | Astrocytes - metabolism | Physiology, Pathological | Serine | Schizophrenia | Physiological aspects | Research | Health aspects | Protein binding
Journal Article
Journal Article
Paediatric Respiratory Reviews, ISSN 1526-0542, 2016, Volume 22, pp. 83 - 88
Journal Article