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1. Full Text Cyclic Peptides Arising by Evolutionary Parallelism via Asparaginyl-Endopeptidase—Mediated Biosynthesis
by Joshua S. Mylne and Lai Yue Chan and Aurelie H. Chanson and Norelle L. Daly and Hanno Schaefer and Timothy L. Bailey and Philip Nguyencong and Laura Cascales and David J. Craik
The Plant cell, ISSN 1040-4651, 7/2012, Volume 24, Issue 7, pp. 2765 - 2778
Proteins | Polymerase chain reaction | Cyclic peptides | DNA | Squashes | Protein precursors | Amino acids | Biosynthesis | Open reading frames | Free energy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Cell Biology | Cyclotides - chemistry | Cystine-Knot Miniproteins - metabolism | Molecular Sequence Data | Cystine-Knot Miniproteins - genetics | Phylogeny | Peptides, Cyclic - chemistry | Peptides, Cyclic - metabolism | Cysteine Endopeptidases - metabolism | Peptides, Cyclic - genetics | Cystine-Knot Miniproteins - chemistry | DNA, Plant - genetics | Protein Structure, Tertiary | Amino Acid Sequence | Models, Molecular | Momordica - metabolism | Cyclotides - genetics | Arabidopsis - metabolism | Arabidopsis - genetics | Sequence Homology, Amino Acid | Sequence Alignment | Gene Amplification | Cyclotides - metabolism | Momordica - genetics | Protein Conformation | Evolution, Molecular | Arabidopsis thaliana | Synthesis | Peptides | Plant genetics | Genetic aspects | Research | Observations | Index Medicus | s
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2. Full Text Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease
by Zhang, Zhentao and Kang, Seong Su and Liu, Xia and Ahn, Eun Hee and Zhang, Zhaohui and He, Li and Iuvone, P Michael and Duong, Duc M and Seyfried, Nicholas T and Benskey, Matthew J and Manfredsson, Fredric P and Jin, Lingjing and Sun, Yi E and Wang, Jian-Zhi and Ye, Keqiang
Nature structural & molecular biology, ISSN 1545-9993, 08/2017, Volume 24, Issue 8, pp. 632 - 642
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proteins | Parkinson Disease - pathology | Animals | Cysteine Endopeptidases - metabolism | Proteolysis | Asparagine - metabolism | Humans | Mice | alpha-Synuclein - metabolism | Protein Aggregation, Pathological | Disease Models, Animal | Index Medicus
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3. Full Text Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease
by Zhang, Zhentao and Zhang, Zhentao and Song, Mingke and Liu, Xia and Kang, Seong S.u and Kwon, Il-Sun and Duong, Duc M and Seyfried, Nicholas T and Hu, William T and Liu, Zhixue and Wang, Jian-Zhi and Cheng, Liming and Sun, Yi E and Yu, Shan P.ing and Levey, Allan I and Ye, Keqiang
Nature medicine, ISSN 1078-8956, 11/2014, Volume 20, Issue 11, pp. 1254 - 1262
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Memory Disorders - physiopathology | Up-Regulation | Phosphorylation | Alzheimer Disease - complications | Calpain - metabolism | Humans | Brain - enzymology | Molecular Sequence Data | tau Proteins - metabolism | Cognition | Synapses - pathology | Memory Disorders - complications | tau Proteins - chemistry | Alzheimer Disease - pathology | Caspases - metabolism | Cysteine Endopeptidases - metabolism | Synapses - metabolism | HEK293 Cells | Memory Disorders - pathology | Neurofibrillary Tangles - pathology | Protein Structure, Tertiary | Amino Acid Sequence | Alzheimer Disease - physiopathology | Solubility | Mice, Transgenic | Alzheimer Disease - enzymology | Gene Knockout Techniques | Aging - pathology | Animals | Asparagine - metabolism | Neurofibrillary Tangles - enzymology | Brain - pathology | Neurotoxins - metabolism | Aged | Asparagine | Physiological aspects | Research | Proteases | Alzheimer's disease | Analysis | Proteins | Pathology | Alzheimers disease | Neurodegeneration | Index Medicus
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4. Full Text IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation
by Jordan, Stanley C and Lorant, Tomas and Choi, Jua and Kjellman, Christian and Winstedt, Lena and Bengtsson, Mats and Zhang, Xiaohai and Eich, Torsten and Toyoda, Mieko and Eriksson, Britt-Marie and Ge, Shili and Peng, Alice and Järnum, Sofia and Wood, Kathryn J and Lundgren, Torbjorn and Wennberg, Lars and Bäckman, Lars and Larsson, Erik and Villicana, Rafael and Kahwaji, Joe and Louie, Sabrina and Kang, Alexis and Haas, Mark and Nast, Cynthia and Vo, Ashley and Tufveson, Gunnar
The New England journal of medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 5, pp. 442 - 453
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Bacterial Proteins - adverse effects | Immunoglobulin G - blood | Histocompatibility Testing | Immunosuppression - methods | Complement C1q - immunology | Humans | Middle Aged | HLA Antigens - immunology | Male | Kidney Transplantation | Bacterial Proteins - therapeutic use | Cysteine Endopeptidases - adverse effects | Adult | Antibodies - blood | Cysteine Endopeptidases - therapeutic use | Female | Transplantation Immunology | Immunoglobulin G - metabolism | Transplantation of organs, tissues, etc | Immunoglobulin G | Research | Immunoglobulin M | Mycophenolic acid | Intravenous administration | Renal function | Glucocorticoids | Transplants & implants | Syngeneic grafts | Clinical trials | Cytotoxicity | Transplantation | Immunoglobulin A | Immunology | Immunoglobulins | Kidneys | Rituximab | Graft rejection | Studies | Pathology | Immunosuppression | Tacrolimus | Globulins | Perfusion | Endopeptidase | Histocompatibility antigen HLA | Kidney diseases | Mycophenolate mofetil | Kidney transplantation | Index Medicus | Abridged Index Medicus | Medicin och hälsovetenskap
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5. Full Text Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases
by Jackson, M.A and Gilding, E.K and Shafee, T and Harris, K.S and Kaas, Q and Poon, S and Yap, K and Jia, H and Guarino, R and Chan, L.Y and Durek, T and Anderson, M.A and Craik, D.J
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2411 - 12
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Plant Proteins - genetics | Plants - metabolism | Cysteine Endopeptidases - metabolism | Sequence Analysis, RNA | Plants - genetics | Cysteine Endopeptidases - genetics | Plants, Genetically Modified | Models, Molecular | Plant Proteins - metabolism | RNA, Plant - genetics | Peptides, Cyclic - biosynthesis | Proteins | Engineering | Molecular modelling | Peptides | Proteolysis | Functional testing | Catalysis | Substrates | Molecular chains | Index Medicus
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6. Full Text SUMO-specific proteases: a twist in the tail
by Hay, Ronald Thomas
Trends in cell biology, ISSN 0962-8924, 2007, Volume 17, Issue 8, pp. 370 - 376
Pathology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Endopeptidases - metabolism | Small Ubiquitin-Related Modifier Proteins - metabolism | Gene Expression Regulation | Ubiquitin - metabolism | Models, Molecular | Humans - classification | Phylogeny | Humans - genetics | Endopeptidases - chemistry | Cysteine Endopeptidases - metabolism | Endopeptidases - genetics | Protein Isoforms - metabolism | Cysteine Endopeptidases - genetics | Saccharomyces cerevisiae Proteins - metabolism | Endopeptidases - classification | Protein Conformation | Protein Processing, Post-Translational | Cysteine Endopeptidases - classification | Ubiquitin | Proteases | Sumo | Index Medicus
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7. Full Text Critical Role for Asparagine Endopeptidase in Endocytic Toll-like Receptor Signaling in Dendritic Cells
by Sepulveda, Fernando E and Maschalidi, Sophia and Colisson, Renaud and Heslop, Lea and Ghirelli, Cristina and Sakka, Emna and Lennon-Duménil, Ana-Maria and Amigorena, Sebastian and Cabanie, Lucien and Manoury, Bénédicte
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2009, Volume 31, Issue 5, pp. 737 - 748
MOLIMMUNO | CELLIMMUNO | Life Sciences & Biomedicine | Immunology | Science & Technology | Animals | Signal Transduction | Cathepsins - metabolism | Cysteine Endopeptidases - genetics | Dendritic Cells - immunology | Mice | Toll-Like Receptor 9 - metabolism | Cysteine Endopeptidases - physiology | Mice, Knockout | Asparagine | Cysteine | Nucleotides | Dendritic cells | RNA | Proteases | Proteins | Medical research | Mutagenesis | Molecular weight | Index Medicus
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8. Full Text Three redundant murein endopeptidases catalyse an essential cleavage step in peptidoglycan synthesis of Escherichia coli K12
by Singh, Santosh Kumar and SaiSree, L and Amrutha, Ravi N and Reddy, Manjula
Molecular microbiology, ISSN 0950-382X, 12/2012, Volume 86, Issue 5, pp. 1036 - 1051
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Bacteriology | Peptidoglycan - metabolism | Endopeptidases - metabolism | Microscopy, Electron, Scanning | Cysteine Endopeptidases - metabolism | Endopeptidases - genetics | Escherichia coli K12 - growth & development | Cysteine Endopeptidases - genetics | Escherichia coli Proteins - genetics | Escherichia coli Proteins - metabolism | Escherichia coli K12 - genetics | Escherichia coli K12 - enzymology | Escherichia coli K12 - ultrastructure | Enzymes | Crosslinked polymers | Chemical properties | Escherichia coli | Membranes | E coli | Molecular biology | Bacterial proteins | Rodents | Index Medicus
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9. Full Text Blockade of Asparagine Endopeptidase Inhibits Cancer Metastasis
by Qi, Qi and Obianyo, Obiamaka and Du, Yuhong and Fu, Haian and Li, Shiyong and Ye, Keqiang
Journal of medicinal chemistry, ISSN 0022-2623, 09/2017, Volume 60, Issue 17, pp. 7244 - 7255
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Humans | Lung Neoplasms - metabolism | Neoplasm Invasiveness - prevention & control | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Structure-Activity Relationship | Breast - metabolism | Breast Neoplasms - metabolism | Cysteine Endopeptidases - metabolism | Lung Neoplasms - secondary | Neoplasm Invasiveness - pathology | Xanthine - pharmacology | Cysteine Proteinase Inhibitors - chemistry | Female | Antineoplastic Agents - pharmacology | Lung - metabolism | Breast - pathology | Cysteine Proteinase Inhibitors - therapeutic use | Lung - pathology | Xanthine - chemistry | Antineoplastic Agents - chemistry | Breast Neoplasms - drug therapy | Animals | Lung Neoplasms - prevention & control | Breast - drug effects | Breast Neoplasms - pathology | Mice, Nude | Cysteine Proteinase Inhibitors - pharmacology | Lung - drug effects | Cell Line, Tumor | Mice | Xanthine - therapeutic use | Index Medicus
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10. Full Text Multiple Associated Proteins Regulate Proteasome Structure and Function
by Leggett, David S and Hanna, John and Borodovsky, Anna and Crosas, Bernat and Schmidt, Marion and Baker, Rohan T and Walz, Thomas and Ploegh, Hidde and