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Journal Article
Oncogene, ISSN 0950-9232, 07/2015, Volume 34, Issue 31, pp. 4056 - 4068
Lung cancer is the leading cause of cancer death worldwide, with metastasis underlying majority of related deaths. Angiomotin (AMOT), a scaffold protein, has... 
YES-ASSOCIATED PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | HIPPO PATHWAY | YAP | PROLIFERATION | CELL BIOLOGY | BREAST-CANCER | OVEREXPRESSION | ONCOLOGY | CELL-MIGRATION | IN-VIVO | GROWTH | GENETICS & HEREDITY | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Humans | Gene Expression Regulation, Neoplastic | Microfilament Proteins - physiology | Lung Neoplasms - pathology | Phosphoproteins - metabolism | Cysteine-Rich Protein 61 - metabolism | Intercellular Signaling Peptides and Proteins - physiology | Intercellular Signaling Peptides and Proteins - metabolism | Cell Transformation, Neoplastic - genetics | Membrane Proteins - physiology | HEK293 Cells | Adenocarcinoma - genetics | Membrane Proteins - metabolism | Microfilament Proteins - metabolism | Lung Neoplasms - genetics | Cysteine-Rich Protein 61 - genetics | Mice, Inbred C57BL | Cell Transformation, Neoplastic - metabolism | Disease Progression | Down-Regulation - genetics | Transcription Factors - metabolism | Animals | Mice, Nude | Cell Line, Tumor | Protein Binding | Mice | Mice, Inbred BALB C | Adaptor Proteins, Signal Transducing - metabolism | Usage | Lung cancer | Stem cells | Physiological aspects | Development and progression | Genetic aspects | Research | Drug therapy | Angiostatin | Health aspects | Signal transduction | Protein expression | Cell growth | Metastasis | Mesenchyme | Transcription | Therapeutic applications | Lung carcinoma | Nuclear transport | Metastases | Yes-associated protein | Human papillomavirus | Tumor suppressor genes | CYR61 protein | Cell migration
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 10/2011, Volume 68, Issue 19, pp. 3149 - 3163
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2011, Volume 286, Issue 11, pp. 9542 - 9554
Retinal vascular damages are the cardinal hallmarks of retinopathy of prematurity (ROP), a leading cause of vision impairment and blindness in childhood. Both... 
PROGENITOR CELLS | VASCULAR DEVELOPMENT | ANGIOGENESIS | GENE | OXYGEN-INDUCED RETINOPATHY | BIOCHEMISTRY & MOLECULAR BIOLOGY | SMOOTH-MUSCLE-CELLS | MECHANICAL REGULATION | MESENCHYMAL STEM-CELLS | CYR61 | ENDOTHELIAL GROWTH-FACTOR | Retina - metabolism | Humans | Retinopathy of Prematurity - genetics | Wnt Proteins - metabolism | Cysteine-Rich Protein 61 - metabolism | Neovascularization, Pathologic - pathology | Retinal Vessels - pathology | Wnt Proteins - genetics | Infant, Newborn | Ischemia - pathology | Cysteine-Rich Protein 61 - pharmacology | Disease Models, Animal | Recombinant Proteins - metabolism | Cell Adhesion - genetics | Retinal Vessels - metabolism | Cysteine-Rich Protein 61 - genetics | Ischemia - metabolism | Recombinant Proteins - genetics | Signal Transduction - genetics | Recombinant Proteins - pharmacology | Cell Adhesion - drug effects | Animals | Ischemia - drug therapy | Retinopathy of Prematurity - drug therapy | Signal Transduction - drug effects | Neovascularization, Pathologic - drug therapy | Mice | Neovascularization, Pathologic - metabolism | Retinopathy of Prematurity - metabolism | Retina - pathology | Retinopathy of Prematurity - pathology | Molecular Bases of Disease | Angiogenesis | Ischemia | Extracellular Matrix Proteins | CCN Proteins | Endothelial Progenitor Cells | Retina | Stem Cell | Oxygen-induced Retinopathy | Cysteine-rich Protein 61 | Endothelium
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 6, pp. 2270 - 2275
Journal Article
Methods, ISSN 1046-2023, 07/2017, Volume 124, pp. 89 - 99
•Protein network construction using RPPA data to identify complex patterns in protein signaling.•Protein networks constructed by analyzing the expression... 
RPPA | Network construction | Breast cancer | MANOVA | Topology analysis | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | PROGRESSION | Multivariate Analysis | RNA, Small Interfering - genetics | Phosphorylation | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Gene Expression Regulation, Neoplastic | Neoplasm Proteins - antagonists & inhibitors | Intracellular Signaling Peptides and Proteins - metabolism | RNA Polymerase II - metabolism | ATPases Associated with Diverse Cellular Activities - genetics | Gene Regulatory Networks | Neoplasm Proteins - metabolism | Cysteine-Rich Protein 61 - metabolism | Breast Neoplasms - metabolism | Protein Array Analysis - statistics & numerical data | MCF-7 Cells | ATPases Associated with Diverse Cellular Activities - metabolism | Tumor Suppressor Proteins - genetics | Female | Neoplasm Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | ATPases Associated with Diverse Cellular Activities - antagonists & inhibitors | Tumor Suppressor Proteins - metabolism | RNA Polymerase II - antagonists & inhibitors | Signal Transduction | Cysteine-Rich Protein 61 - genetics | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Cysteine-Rich Protein 61 - antagonists & inhibitors | Proteasome Endopeptidase Complex - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | RNA Polymerase II - genetics | Protein Processing, Post-Translational | Proteasome Endopeptidase Complex - metabolism | RNA, Small Interfering - metabolism | Proteins | Analysis | breast cancer | topology analysis | network construction
Journal Article
Epigenetics, ISSN 1559-2294, 08/2017, Volume 12, Issue 8, pp. 653 - 661
Infertility affects one in 6 couples in developed nations, resulting in an increasing use of assisted reproductive technologies (ART). Both ART and... 
imprinted genes | IVF | birth weight | placenta | ART | subfertility | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIRTH-WEIGHT | DEVELOPMENTAL ORIGINS | CHILDREN | DNA METHYLATION DIFFERENCES | IN-VITRO | GROWTH | GENETICS & HEREDITY | GENE-EXPRESSION | INFERTILITY | OUTCOMES | Genomic Imprinting | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Male | Cysteine-Rich Protein 61 - metabolism | Case-Control Studies | PAX8 Transcription Factor - metabolism | Infertility - genetics | DNA Methylation | Insulin-Like Growth Factor II - genetics | Tumor Suppressor Proteins - genetics | Hyaluronan Receptors - metabolism | Adult | Female | GRB10 Adaptor Protein - metabolism | Oxidoreductases Acting on CH-CH Group Donors - genetics | Ribonucleoproteins - genetics | Nuclear Proteins - genetics | Infant, Newborn | Fertilization in Vitro - adverse effects | PAX8 Transcription Factor - genetics | Tumor Suppressor Proteins - metabolism | Cysteine-Rich Protein 61 - genetics | Nuclear Proteins - metabolism | Ribonucleoproteins - metabolism | GRB10 Adaptor Protein - genetics | Hyaluronan Receptors - genetics | Nerve Tissue Proteins - genetics | Insulin-Like Growth Factor II - metabolism | Nerve Tissue Proteins - metabolism | Oxidoreductases Acting on CH-CH Group Donors - metabolism | Placenta - metabolism | Pregnancy
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 7391 - 11
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 05/2016, Volume 55, Issue 5, pp. 622 - 632
Anaplastic thyroid cancer (ATC) is among the most aggressive types of malignant cancer. Epidermal growth factor (EGF) plays a crucial role in the pathogenesis... 
Anaplastic thyroid cancer | Epidermal growth factor | Cysteine‐rich protein 61 | Migration | Cysteine-rich protein 61 | ACTIVATION | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | BREAST-CANCER | INVASIVENESS | ANGIOGENIC FACTOR CYR61 | C-ERBB-2 PROTEIN | FACTOR RECEPTOR EGFR | ONCOLOGY | GENE-EXPRESSION | CARCINOMA | Cysteine-Rich Protein 61 - genetics | Humans | Epidermal Growth Factor - metabolism | Epithelial-Mesenchymal Transition - drug effects | Thyroid Carcinoma, Anaplastic - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | Cysteine-Rich Protein 61 - metabolism | Cell Movement - drug effects | Thyroid Neoplasms - genetics | Signal Transduction - drug effects | Cyclic AMP Response Element-Binding Protein - metabolism | Cell Line, Tumor | Thyroid Carcinoma, Anaplastic - pathology | Thyroid Carcinoma, Anaplastic - metabolism | Phosphorylation - drug effects | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Cysteine | RNA | Antibodies | Cyclic adenylic acid | Thyroid gland | Metastasis | Cystine | Viral antibodies | Thyroid cancer | Stem cells | Intermediate filament proteins | Protein binding | Proteins | Cancer therapies | Cell adhesion & migration | Phosphorylation | Pathogenesis | Markers | Kinases | E-cadherin | Promoters | Growth factors | Recombinant | Cancer
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2019, Volume 10, Issue 1, pp. 4198 - 14
Maintenance of high-turnover tissues such as the epidermis requires a balance between stem cell proliferation and differentiation. The molecular mechanisms... 
STEM-CELLS | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | TISSUE | SELF-RENEWAL | ALPHA | TERMINATION | EXPRESSION | BINDING | NUCLEAR RIBONUCLEOPROTEIN-K | REVEALS | Humans | ErbB Receptors - genetics | Stem Cells - cytology | RNA, Messenger - metabolism | Stem Cells - metabolism | Cysteine-Rich Protein 61 - metabolism | DNA-Binding Proteins - metabolism | Cell Differentiation - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Kruppel-Like Transcription Factors - metabolism | Cell Differentiation - physiology | RNA Stability - physiology | Epidermis - metabolism | Cell Proliferation - genetics | ErbB Receptors - metabolism | Cysteine-Rich Protein 61 - genetics | Cell Proliferation - physiology | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Heterogeneous-Nuclear Ribonucleoprotein K - genetics | RNA Stability - genetics | Transcription Factors - metabolism | Heterogeneous-Nuclear Ribonucleoprotein K - metabolism | Kruppel-Like Transcription Factors - genetics | Binding | Cell proliferation | Post-transcription | Transcription factors | Epidermal growth factor receptors | Genes | Epidermis | RNA polymerase | Myc protein | Cell differentiation | Progenitor cells | DNA-directed RNA polymerase | Cyclins | Degradation | Polymerase | Molecular modelling | KLF4 protein | Stem cells | CYR61 protein | Differentiation | RNA polymerase II
Journal Article
Journal Article