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Drug metabolism and disposition, ISSN 1521-009X, 01/2010, Volume 38, Issue 1, pp. 92 - 99
.... CYP1A2, CYP2B6, and CYP2C19 catalyzed this reaction. In the same system using 2-oxo-clopidogrel as the substrate, detection of the active metabolite of clopidogrel required the addition of glutathione to the system... 
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Microsomes - metabolism | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Cytochrome P-450 Enzyme System - metabolism | Sulfaphenazole - pharmacology | Microsomes - drug effects | Cytochrome P-450 CYP3A - genetics | Cytochrome P-450 CYP1A2 - genetics | Antibodies - immunology | Omeprazole - pharmacology | Microsomes, Liver - enzymology | Platelet Aggregation Inhibitors - pharmacokinetics | Ticlopidine - pharmacokinetics | Oxidoreductases, N-Demethylating - metabolism | Aryl Hydrocarbon Hydroxylases - immunology | Oxidation-Reduction | Enzyme Inhibitors - pharmacology | Ticlopidine - analogs & derivatives | Oxidoreductases, N-Demethylating - immunology | Cytochrome P-450 CYP3A - metabolism | Cell Line, Tumor | Cytochrome P-450 Enzyme System - genetics | Theophylline - pharmacology | Kinetics | Cytochrome P-450 CYP2C9 | Theophylline - analogs & derivatives | Oxidoreductases, N-Demethylating - genetics | Glutathione - metabolism | Ketoconazole - pharmacology | Biotransformation - physiology | Cytochrome P-450 CYP1A2 Inhibitors | Microsomes, Liver - drug effects | Ticlopidine - metabolism | NADP - metabolism | Platelet Aggregation Inhibitors - metabolism | Cytochrome P-450 CYP3A - immunology | Cell Line | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Cytochrome P-450 CYP1A2 - immunology | Biocatalysis | Mephenytoin - analogs & derivatives | Cytochrome P-450 CYP1A2 - metabolism | Aryl Hydrocarbon Hydroxylases - metabolism | Mephenytoin - pharmacology | Antibodies - pharmacology | Cytochrome P-450 CYP3A Inhibitors | Cytochrome P-450 CYP2C19 | Clopidogrel | Cytochrome P-450 CYP2B6 | Index Medicus
Journal Article
Journal Article
Journal Article
Drug metabolism and disposition, ISSN 1521-009X, 12/2008, Volume 36, Issue 12, pp. 2547 - 2555
.... CYP1A2 is generally considered to be the major enzyme involved in the biotransformation of CLZ to its N -demethylated (norCLZ) and N -oxygenated (CLZ N -oxide... 
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Cytochrome P-450 CYP2C9 | Clozapine - metabolism | Oxidoreductases, N-Demethylating - genetics | Cytochrome P-450 Enzyme Inhibitors | Humans | Microsomes, Liver - metabolism | Aryl Hydrocarbon Hydroxylases - genetics | Biotransformation - genetics | Cytochrome P-450 Enzyme System - metabolism | Dextromethorphan - metabolism | Ketoconazole - pharmacology | Oxygenases - antagonists & inhibitors | Cytochrome P-450 CYP1A2 Inhibitors | Testosterone - metabolism | Cytochrome P-450 CYP3A - genetics | Isoenzymes - metabolism | Microsomes, Liver - drug effects | Oxygenases - metabolism | Cytochrome P-450 CYP1A2 - genetics | Catalysis | Oxidoreductases, N-Demethylating - metabolism | Tolbutamide - metabolism | Recombinant Proteins - metabolism | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Oxidation-Reduction | Isoenzymes - genetics | Enzyme Inhibitors - pharmacology | Clozapine - analogs & derivatives | Cytochrome P-450 CYP1A1 - metabolism | Cytochrome P-450 CYP1A2 - metabolism | Fluvoxamine - pharmacology | Aryl Hydrocarbon Hydroxylases - metabolism | Cytochrome P-450 CYP3A Inhibitors | Cytochrome P-450 CYP3A - metabolism | Biotransformation - drug effects | Alleles | Cytochrome P-450 Enzyme System - genetics | Kinetics | Oxygenases - genetics | Cytochrome P-450 CYP2B6 | Isoenzymes - antagonists & inhibitors | Index Medicus
Journal Article
Clinical pharmacology and therapeutics, ISSN 0009-9236, 12/2018, Volume 104, Issue 6, pp. 1249 - 1259
Journal Article
Environmental science and pollution research international, ISSN 0944-1344, 6/2018, Volume 25, Issue 17, pp. 16420 - 16426
Journal Article
Journal Article
Journal Article
Archives of toxicology, ISSN 0340-5761, 2/2016, Volume 90, Issue 2, pp. 279 - 290
Journal Article
Journal Article