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Drug Metabolism and Disposition, ISSN 0090-9556, 04/2003, Volume 31, Issue 4, pp. 421 - 431
Journal Article
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2000, Volume 273, Issue 1, pp. 333 - 341
Human hepatocytes cultured serum-free for up to 6 weeks were used to study expression and induction of enzymes and membrane transport proteins involved in drug... 
P-glycoprotein | human hepatocytes | barbiturates | Cytochrome P450 | aromatic hydrocarbons | multidrug-resistance-associated protein | antibiotics | Antibiotics | Human hepatocytes | Aromatic hydrocarbons | Barbiturates | Multidrug-resistance-associated protein | CANALICULAR MEMBRANE | RAT HEPATOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | cytochrome P450 | PRIMARY CULTURES | IDENTIFICATION | BIOPHYSICS | METABOLISM | GENE FAMILY | GROWTH-FACTOR | EXPRESSION | HUMAN-LIVER | Cytochrome P-450 CYP2C9 | Isoenzymes - analysis | Mixed Function Oxygenases - biosynthesis | Phenobarbital - pharmacology | Steroid Hydroxylases - metabolism | Liver - enzymology | Cytochrome P-450 CYP3A | Humans | Vault Ribonucleoprotein Particles - genetics | Cytochrome P-450 Enzyme System - metabolism | Mixed Function Oxygenases - metabolism | Cytochrome P-450 CYP2E1 - metabolism | Steroid 16-alpha-Hydroxylase | Hepatocyte Growth Factor - pharmacology | RNA, Messenger - metabolism | Methylcholanthrene - pharmacology | ATP-Binding Cassette Transporters - genetics | Liver - drug effects | beta-Naphthoflavone - pharmacology | ATP Binding Cassette Transporter, Subfamily B, Member 1 - analysis | Enzyme Induction - drug effects | Neoplasm Proteins - genetics | Cytochrome P-450 Enzyme System - analysis | Liver - ultrastructure | Cell Size - drug effects | RNA, Messenger - genetics | Cells, Cultured | Cytochrome P-450 CYP1A1 - metabolism | Cytochrome P-450 CYP1A2 - metabolism | Blotting, Western | ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics | ATP-Binding Cassette Transporters - analysis | Cytochrome P-450 CYP1A2 - biosynthesis | Cytochrome P-450 CYP2C19 | Cytochrome P-450 Enzyme System - biosynthesis | Liver - cytology | Cytochrome P-450 CYP1A1 - biosynthesis | Epidermal Growth Factor - pharmacology | Rifampin - pharmacology | Isoenzymes - biosynthesis | Aryl Hydrocarbon Hydroxylases | Multidrug Resistance-Associated Proteins
Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 09/2016, Volume 119, Issue 3, pp. 284 - 290
Cytochrome P450 (CYP) activity can be assessed using a ‘cocktail’ phenotyping approach. Recently, we have developed a cocktail (Geneva cocktail) which combines... 
2D6 | PARAXANTHINE | BUPROPION | IN-VIVO | PHARMACOLOGY & PHARMACY | TOXICOLOGY | FLURBIPROFEN | METABOLIZING-ENZYMES | COOPERSTOWN 5+1 COCKTAIL | ORAL-CONTRACEPTIVES | P-GLYCOPROTEIN | Caffeine - administration & dosage | Humans | Midazolam - administration & dosage | Male | Genotyping Techniques | Cytochrome P-450 CYP2B6 - metabolism | Terfenadine - administration & dosage | Caffeine - pharmacokinetics | Dose-Response Relationship, Drug | Young Adult | Drug Interactions | Cytochrome P-450 CYP3A - genetics | Dried Blood Spot Testing - methods | Cytochrome P-450 CYP1A2 - genetics | Flurbiprofen - administration & dosage | Adult | Female | Dextromethorphan - pharmacokinetics | Cytochrome P-450 CYP2C9 - metabolism | Terfenadine - pharmacokinetics | Bupropion - pharmacokinetics | Cytochrome P-450 CYP2D6 - genetics | Flurbiprofen - pharmacokinetics | Cytochrome P-450 CYP2B6 - genetics | Omeprazole - administration & dosage | Cytochrome P-450 CYP2C19 - genetics | Terfenadine - analogs & derivatives | Omeprazole - pharmacokinetics | Midazolam - pharmacokinetics | Cytochrome P-450 CYP1A2 - metabolism | Bupropion - administration & dosage | Cytochrome P-450 CYP2C9 - genetics | Cross-Over Studies | Phenotype | Cytochrome P-450 CYP3A - metabolism | Adolescent | Cytochrome P-450 CYP2D6 - metabolism | Cytochrome P-450 Enzyme System - genetics | Cytochrome P-450 CYP2C19 - metabolism | Dextromethorphan - administration & dosage | Medical examination | Drug interactions | Analysis | Methods | Blood | Cytochrome P-450 | Confidence intervals | Cytochrome | Prescription drugs | Drug dosages | Index Medicus
Journal Article
Drug Design, Development and Therapy, ISSN 1177-8881, 03/2017, Volume 11, pp. 1043 - 1053
Journal Article
European Journal of Clinical Pharmacology, ISSN 0031-6970, 10/2014, Volume 70, Issue 10, pp. 1203 - 1210
Journal Article
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 04/2019, Volume 139, Issue 4, pp. 361 - 366
Polymorphisms of cytochrome P450 (CYP) enzymes can affect enzymatic activity, drug metabolism and drug interactions. Although the potential for drug... 
Omeprazole | Drug interaction | Rifampicin | Cytochrome P450 2C19 | Fluvoxamine | ALLELE | LANSOPRAZOLE | POLYMORPHISM | IMPACT | COCKTAIL | THERAPY | METABOLISM | PHARMACOLOGY & PHARMACY | Dosage and administration | Research | Genetic polymorphisms | Cytochrome P-450
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 06/2014, Volume 95, Issue 6, pp. 653 - 662
Journal Article