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Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, pp. e0132992 - e0132992
Human pluripotent stem cell-derived hepatocytes have the potential to provide in vitro model systems for drug discovery and hepatotoxicity testing. However,... 
DNA METHYLATION | HUMAN LUNG | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | PLACENTA | HUMAN LIVER | HUMAN CYP1A1 | MECHANISMS | CYP2E1 | DIFFERENTIATION | EXPRESSION | Chromatin - metabolism | Cytochrome P-450 CYP1A1 - genetics | Cytochrome P-450 CYP1B1 - genetics | Epigenesis, Genetic | Human Embryonic Stem Cells - cytology | Humans | Cytochrome P-450 CYP1B1 - metabolism | Cytochrome P-450 CYP2E1 - genetics | Cytochrome P-450 CYP2E1 - metabolism | Hepatocytes - metabolism | DNA Methylation | Hepatocytes - cytology | Cytochrome P-450 CYP1A2 - genetics | Transcription, Genetic | Cell Differentiation | Chromatin - ultrastructure | Cell Line | Cytochrome P-450 CYP2D6 - genetics | Human Embryonic Stem Cells - metabolism | DNA Modification Methylases - metabolism | Histone Deacetylases - genetics | Signal Transduction | Histone Deacetylases - metabolism | Cytochrome P-450 CYP1A1 - metabolism | Organ Specificity | Cytochrome P-450 CYP1A2 - metabolism | DNA Modification Methylases - genetics | Histones - genetics | CpG Islands | Cytochrome P-450 CYP2D6 - metabolism | Protein Processing, Post-Translational | Histones - metabolism | Primary Cell Culture | Epigenetic inheritance | Methylation | Embryonic stem cells | Genes | Cytochrome P-450 | Cytochrome | Chromatin | Transcription | Toxicity | Gene regulation | Liver | Science | Demethylation | Rodents | Toxicity testing | DNA methylation | Inhibition | Hepatotoxicity | CYP2D6 protein | Deoxyribonucleic acid--DNA | CpG islands | Enzymes | Cytochrome P450 | CYP1A2 protein | Gene expression | Hepatocytes | Stem cells | Pluripotency | Combinatorial analysis | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2013, Volume 65, pp. 1238 - 1245
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 57, Issue 4, pp. 860 - 866
Journal Article
Journal Article
Hepatology, ISSN 0270-9139, 05/2013, Volume 57, Issue 5, pp. 1773 - 1783
Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 2011, Volume 121, Issue 2, pp. 207 - 233
Journal Article