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The Journal of biological chemistry, ISSN 0021-9258, 11/2008, Volume 283, Issue 48, pp. 33698 - 33707
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Acetaminophen - adverse effects | Arachidonic Acid - metabolism | Heme - metabolism | Cytochrome P-450 CYP2E1 Inhibitors | Enzyme Inhibitors - metabolism | Nitrosamines - metabolism | Humans | Imidazoles - chemistry | Models, Molecular | Cytochrome P-450 CYP2E1 - metabolism | Hydroxylation - physiology | Carcinogens - metabolism | Smoking - metabolism | Heme - chemistry | Hydrogen Bonding | Analgesics, Non-Narcotic - adverse effects | Enzyme Inhibitors - chemistry | Hydrophobic and Hydrophilic Interactions | Protein Structure, Secondary - physiology | Xenobiotics - metabolism | Cytochrome P-450 CYP2E1 - chemistry | Imidazoles - metabolism | Index Medicus
Journal Article
Drug metabolism and disposition, ISSN 0090-9556, 10/2009, Volume 37, Issue 10, pp. 2087 - 2094
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Biological and medical sciences | Medical sciences | Liver. Biliary tract. Portal circulation. Exocrine pancreas | Other diseases. Semiology | Pharmacology. Drug treatments | Cytochrome P-450 CYP2C9 | Fatty Liver - genetics | Cytochrome P-450 CYP2D6 - genetics | Oxidoreductases, N-Demethylating - genetics | Fatty Liver - metabolism | Fatty Liver - pathology | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Cytochrome P-450 Enzyme System - metabolism | Cytochrome P-450 CYP2E1 - genetics | Cytochrome P-450 CYP2E1 - metabolism | RNA, Messenger - metabolism | Cytochrome P-450 CYP1A2 - metabolism | Disease Progression | Aryl Hydrocarbon Hydroxylases - metabolism | Cytochrome P-450 CYP3A - genetics | Cytochrome P-450 CYP2C19 | Cytochrome P-450 CYP1A2 - genetics | Fatty Liver - enzymology | Cytochrome P-450 CYP2D6 - metabolism | Cytochrome P-450 Enzyme System - genetics | Microsomes, Liver - enzymology | Oxidoreductases, N-Demethylating - metabolism | Cytochrome P-450 CYP2B6 | Index Medicus
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 03/2012, Volume 302, Issue 5, pp. 532 - 539
Energy expenditure | Endocrinology & Metabolism | Physiology | Life Sciences & Biomedicine | Science & Technology | Liver - pathology | Hyperlipidemias - blood | Fatty Liver - pathology | Adipose Tissue, White - metabolism | Diet, High-Fat - adverse effects | Male | Cytochrome P-450 CYP2E1 - genetics | Mice, 129 Strain | Muscle Fibers, Skeletal - metabolism | Molecular Targeted Therapy | Glucose Intolerance - blood | Glucose Intolerance - prevention & control | Biological Transport | Glucose Intolerance - etiology | Cytochrome P-450 CYP2E1 - physiology | Obesity - etiology | Cytokines - blood | Signal Transduction | Liver - metabolism | Fatty Liver - prevention & control | Insulin Resistance | Obesity - physiopathology | Hyperlipidemias - prevention & control | Mice, Knockout | Obesity - metabolism | Insulin - metabolism | Animals | Hyperlipidemias - etiology | Obesity - prevention & control | Glucose - metabolism | Mice | Fatty Liver - etiology | Obesity | Cytokines | Diet | Rodents | Motor ability | Insulin resistance | Glucose | Index Medicus | energy expenditure
Journal Article
Scientific reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 12331 - 11
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Drug Overdose - metabolism | Up-Regulation | Drug Overdose - blood | Humans | 3' Untranslated Regions - genetics | Child, Preschool | Male | MicroRNAs - metabolism | Cytochrome P-450 CYP2E1 - genetics | Cytochrome P-450 CYP2E1 - metabolism | Cytochrome P-450 CYP3A - genetics | Cytochrome P-450 CYP1A2 - genetics | Drug Overdose - etiology | Female | Protein Biosynthesis - genetics | Binding Sites | Child | Cell Line | Drug Overdose - genetics | Acetaminophen - toxicity | Cytochrome P-450 CYP1A2 - metabolism | Hepatocytes | Cytochrome P-450 CYP3A - metabolism | Adolescent | MicroRNAs - blood | Toxicity | Cytochrome P450 | mRNA | CYP1A2 protein | Protein adducts | Analgesics | 3' Untranslated regions | Acetaminophen | Isoforms | miRNA | Overdose | Children | Binding sites | Index Medicus
Journal Article
Drug metabolism and disposition, ISSN 0090-9556, 07/2007, Volume 35, Issue 7, pp. 1223 - 1231
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Liver - pathology | Liver - enzymology | Cytochrome P-450 Enzyme Inhibitors | Ethanol - toxicity | Glutathione - metabolism | Liver Diseases - pathology | Cytochrome P-450 Enzyme System - metabolism | Male | Alanine Transaminase - blood | Cytochrome P-450 CYP2E1 - genetics | Cytochrome P-450 CYP2E1 - metabolism | Testosterone - metabolism | Glucuronides - metabolism | Liver - drug effects | Enzyme Induction - drug effects | Troleandomycin - pharmacology | Benzoquinones - metabolism | Disease Models, Animal | Severity of Illness Index | Hydroxylation | Imines - metabolism | Enzyme Inhibitors - pharmacology | Cytochrome P-450 CYP1A2 - metabolism | Mice, Knockout | Drug Synergism | Cytochrome P-450 CYP2E1 - deficiency | Animals | Acetaminophen | Cytochrome P-450 Enzyme System - biosynthesis | Chemical and Drug Induced Liver Injury | Mice | Liver Diseases - metabolism | Pentanols - toxicity | Index Medicus
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CYP Induction-Mediated Drug Interactions: in Vitro Assessment and Clinical Implications
Pharmaceutical research, ISSN 0724-8741, 6/2006, Volume 23, Issue 6, pp. 1089 - 1116
Biochemistry, general | glucocorticoid receptor | interindividual variability | cross talk | pregnane X receptor | aryl hydrocarbon receptor | xenobiotic responsive elements | Biomedical Engineering | hepatic and intestinal CYP induction | Biomedicine | constitutive androstane receptor | Pharmacy | Medical Law | species differences | Pharmacology/Toxicology | in vitro / in vivo extrapolation | Aryl hydrocarbon receptor | In vitro/in vivo extrapolation | Interindividual variability | Pregnane X receptor | Glucocorticoid receptor | Cross talk | Constitutive androstane receptor | Species differences | Hepatic and intestinal CYP induction | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Cytochrome P-450 CYP2B1 - genetics | Cytochrome P-450 CYP3A - biosynthesis | Liver - enzymology | Receptor Cross-Talk | Receptors, Steroid - metabolism | Species Specificity | Humans | Cytochrome P-450 CYP2E1 - genetics | Pharmacology | Receptors, Cytoplasmic and Nuclear - genetics | Cytochrome P-450 CYP2E1 - biosynthesis | Genetic Variation | Transcription Factors - metabolism | Enzyme Induction - genetics | Animals | Drug Interactions | Cytochrome P-450 CYP3A - genetics | Liver - drug effects | Drug Design | Enzyme Induction - drug effects | Receptors, Aryl Hydrocarbon - metabolism | Pharmacokinetics | Cytochrome P-450 CYP2B1 - biosynthesis | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus
Journal Article
Pharmaceutical biology, ISSN 1388-0209, 01/2017, Volume 55, Issue 1, pp. 1868 - 1874
CYP2E1 | CYP3A4 | CYP2D6 | Ampelopsis grossedentata | herb-drug interaction | Drug interaction | herb–drug interaction | Herb | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Plant Sciences | Medical Laboratory Technology | Science & Technology | Binding, Competitive | Cytochrome P-450 CYP3A Inhibitors - pharmacology | Humans | Microsomes, Liver - metabolism | Cytochrome P-450 CYP2D6 - chemistry | Antioxidants - pharmacology | Cytochrome P-450 CYP2E1 - metabolism | Cytochrome P-450 CYP2E1 Inhibitors - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Cytochrome P-450 CYP3A - metabolism | Microsomes, Liver - drug effects | Cytochrome P-450 CYP3A - chemistry | Cytochrome P-450 CYP2D6 - metabolism | Microsomes, Liver - enzymology | Flavonols - pharmacology | Kinetics | Antineoplastic Agents, Phytogenic - pharmacology | Cytochrome P-450 CYP2D6 Inhibitors - pharmacology | Cytochrome P-450 CYP2E1 - chemistry | Cytochrome | Enzymes | Flavonoids | Liver | Cytochrome P450 | Isoforms | Enzyme kinetics | Microsomes | CYP2D6 protein | Index Medicus | cyp3a4 | cyp2e1 | ampelopsis grossedentata | cyp2d6
Journal Article
The Journal of biological chemistry, 12/2017, Volume 292, Issue 51, p. 20818
Humans | Cytochrome P-450 CYP2D6 - chemistry | Cytochrome P-450 Enzyme System - metabolism | Substrate Specificity | Cytochrome P-450 CYP2E1 - genetics | Cytochrome P-450 CYP2E1 - metabolism | Cytochromes b5 - chemistry | Cytochromes b5 - metabolism | Cytochrome P-450 CYP3A - genetics | Solutions | Cytochrome P-450 CYP3A - chemistry | Nuclear Magnetic Resonance, Biomolecular | Protein Interaction Domains and Motifs | Cytochrome P-450 CYP2E1 - chemistry | Cytochrome P-450 CYP2D6 - genetics | Biocatalysis | Mutagenesis, Site-Directed | Cytochrome P-450 CYP2A6 - genetics | Cytochrome P-450 CYP2A6 - metabolism | Cytochrome P-450 Enzyme System - chemistry | Cytochrome P-450 CYP3A - metabolism | Cytochrome P-450 CYP2D6 - metabolism | Cytochrome P-450 Enzyme System - genetics | Protein Conformation | Kinetics | Mutation | Cytochrome P-450 CYP2A6 - chemistry | Amino Acid Substitution
Journal Article
Journal of ethnopharmacology, ISSN 0378-8741, 05/2015, Volume 166, pp. 66 - 73
Drug–herb interactions | Enzyme inhibition | Alkaloids | Gelsemium elegans | Cytochrome P450 | Cytochrome | Drug-herb interactions | P450 | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Integrative & Complementary Medicine | Plant Sciences | Science & Technology | Plant Extracts - chemistry | Cytochromes - antagonists & inhibitors | Alkaloids - pharmacology | Plant Extracts - pharmacology | Rats | Gelsemium - chemistry | Cytochrome P-450 CYP2E1 - metabolism | Cytochrome P-450 CYP2A6 - antagonists & inhibitors | Cytochrome P-450 Enzyme Inhibitors - pharmacology | Animals | Cytochrome P-450 CYP3A - metabolism | Microsomes, Liver - drug effects | Plant Roots - chemistry | Cytochrome P-450 CYP1A2 | Cytochrome P-450 Enzyme Inhibitors - chemistry | Microsomes, Liver - enzymology | Alkaloids - chemistry | Psoriasis | Cytochrome P-450 | Index Medicus
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