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Journal Article
Cancer Research, ISSN 0008-5472, 12/2012, Volume 72, Issue 23, pp. 6142 - 6152
Androgen receptor (AR) signaling persists in castration-resistant prostate carcinomas (CRPC), because of several mechanisms that include increased AR... 
STEROIDOGENESIS | SELECTIVE INHIBITOR | DIHYDROTESTOSTERONE LEVELS | ONCOLOGY | ABIRATERONE ACETATE | RECEPTOR | INCREASED SURVIVAL | CYP17 INHIBITOR | CASTRATION | I CLINICAL-TRIAL | HORMONAL-THERAPY | 3-Hydroxysteroid Dehydrogenases - biosynthesis | Immunohistochemistry | Neoplasms, Hormone-Dependent - metabolism | Prostatic Neoplasms - metabolism | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Transcriptome | Androgens - biosynthesis | Data Mining | Male | Hydroxyprostaglandin Dehydrogenases - metabolism | Neoplasms, Hormone-Dependent - genetics | RNA, Messenger - biosynthesis | Neoplasm Metastasis | Prostatic Neoplasms - genetics | Cytochrome P-450 CYP3A - genetics | Receptors, Androgen - biosynthesis | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Neoplasms, Hormone-Dependent - enzymology | Cytochrome P-450 CYP3A - biosynthesis | Prostatic Neoplasms - pathology | RNA, Messenger - genetics | Hydroxyprostaglandin Dehydrogenases - biosynthesis | Hydroxyprostaglandin Dehydrogenases - genetics | Orchiectomy | Gene Expression Regulation, Enzymologic | Receptors, Androgen - genetics | Aldo-Keto Reductase Family 1 Member C3 | Cytochrome P-450 CYP3A - metabolism | Neoplasms, Hormone-Dependent - pathology | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - biosynthesis | Cell Line, Tumor | Prostatic Neoplasms - enzymology | 3-Hydroxysteroid Dehydrogenases - genetics | Androgens - metabolism | Index Medicus | abiraterone | androgen synthesis | testosterone | dihydrotestosterone | AKR1C3 | CYP17 | MDV3100 (enzalutamide) | Prostate cancer
Journal Article
Journal Article
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 03/2007, Volume 81, Issue 3, pp. 362 - 370
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 08/2008, Volume 36, Issue 8, pp. 1698 - 1708
Although approaches to the prediction of drug-drug interactions (DDIs) arising via time-dependent inactivation have recently been developed, such approaches do... 
CYTOCHROME-P450 | PHARMACOLOGY & PHARMACY | VERAPAMIL | Cytochrome P-450 CYP3A - biosynthesis | Cytochrome P-450 CYP3A Inhibitors | Drug Interactions | Enzyme Inhibitors - pharmacokinetics | Area Under Curve | Models, Biological | Humans | Enzyme Inhibitors - pharmacology | Enzyme Induction | In Vitro Techniques | Index Medicus
Journal Article
Journal Article
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 02/2014, Volume 95, Issue 2, pp. 133 - 135
In 1973, Malcolm Rowland and associates described an approach to predicting clinical pharmacokinetic drug–drug interactions (DDIs) using an inhibition constant... 
PHARMACOLOGY & PHARMACY | INHIBITION | Cytochrome P-450 CYP3A - biosynthesis | Cytochrome P-450 CYP3A Inhibitors | Drug Interactions | Drugs, Investigational - adverse effects | Humans | Index Medicus | Abridged Index Medicus
Journal Article