X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (6625) 6625
Newsletter (1103) 1103
Publication (629) 629
Newspaper Article (281) 281
Book Review (104) 104
Book Chapter (79) 79
Dissertation (28) 28
Book / eBook (11) 11
Data Set (10) 10
Conference Proceeding (6) 6
Magazine Article (5) 5
Reference (2) 2
Transcript (2) 2
Web Resource (2) 2
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (4428) 4428
pharmacology & pharmacy (2901) 2901
index medicus (2813) 2813
cytochrome p-450 (2462) 2462
metabolism (1886) 1886
cytochrome p-450 enzyme system - metabolism (1757) 1757
male (1643) 1643
cytochrome p450 (1503) 1503
animals (1477) 1477
research (1317) 1317
female (1289) 1289
pharmacokinetics (1256) 1256
drug interactions (1238) 1238
enzymes (1117) 1117
cytochrome p-450 cyp3a (1110) 1110
cytochrome (1005) 1005
adult (952) 952
toxicology (906) 906
cytochrome p-450 cyp3a - metabolism (873) 873
physiological aspects (870) 870
in-vitro (837) 837
cytochrome-p450 3a4 (792) 792
cyp3a4 (787) 787
middle aged (777) 777
biochemistry & molecular biology (756) 756
liver (692) 692
cytochrome p-450 enzyme system - genetics (685) 685
analysis (671) 671
inhibition (642) 642
rats (635) 635
cytochrome p-450 enzyme inhibitors (629) 629
microsomes, liver - enzymology (626) 626
expression (610) 610
human liver-microsomes (608) 608
metabolites (606) 606
kinetics (597) 597
microsomes, liver - metabolism (572) 572
p-glycoprotein (522) 522
pharmacology (514) 514
reports (514) 514
drugs (506) 506
enzyme inhibitors - pharmacology (479) 479
drug metabolism (468) 468
hydroxylation (466) 466
cytochrome p-450 cyp3a - genetics (459) 459
aged (451) 451
chemistry, medicinal (444) 444
biotransformation (439) 439
cancer (428) 428
proteins (422) 422
microsomes, liver - drug effects (421) 421
drug-interactions (413) 413
dose-response relationship, drug (407) 407
article (393) 393
induction (373) 373
3a4 (370) 370
drug-metabolism (368) 368
identification (368) 368
mice (367) 367
universities and colleges (363) 363
chemistry, multidisciplinary (362) 362
area under curve (350) 350
health aspects (346) 346
gene expression (345) 345
substrate specificity (344) 344
cytochromes p450 (342) 342
pharmacogenetics (339) 339
oxidation (335) 335
oncology (334) 334
genotype (317) 317
chromatography, high pressure liquid (315) 315
mixed function oxygenases - metabolism (314) 314
genetic aspects (309) 309
liver - enzymology (308) 308
drug dosages (305) 305
oxidation-reduction (302) 302
cytochrome p-450 enzyme system - chemistry (301) 301
liver - metabolism (299) 299
medicine (299) 299
drug-drug interactions (296) 296
pharmacology/toxicology (296) 296
drug therapy (292) 292
recombinant proteins - metabolism (290) 290
toxicity (289) 289
administration, oral (278) 278
cytochrome p-450 cyp3a inhibitors (278) 278
in vitro techniques (277) 277
isoenzymes - metabolism (277) 277
cytochrome p450 3a4 (266) 266
microsomes (265) 265
activation (263) 263
research article (262) 262
aryl hydrocarbon hydroxylases - metabolism (259) 259
mass spectrometry (257) 257
p450 (255) 255
rats, sprague-dawley (254) 254
care and treatment (252) 252
midazolam (251) 251
cytochrome-p450 (244) 244
models, molecular (241) 241
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (7988) 7988
Japanese (36) 36
Chinese (25) 25
French (25) 25
Spanish (14) 14
German (12) 12
Russian (10) 10
Korean (8) 8
Norwegian (2) 2
Polish (2) 2
Portuguese (2) 2
Turkish (2) 2
Czech (1) 1
Dutch (1) 1
Hungarian (1) 1
Italian (1) 1
Romanian (1) 1
Slovak (1) 1
Slovenian (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2006, Volume 103, Issue 37, pp. 13682 - 13687
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2013, Volume 135, Issue 23, pp. 8542 - 8551
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 10/2016, Volume 44, Issue 10, pp. 1584 - 1597
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 2005, Volume 30, Issue 1, pp. 5 - 7
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2004, Volume 279, Issue 37, pp. 38091 - 38094
The structure of P450 3A4 was determined by x-ray crystallography to 2.05-Å resolution. P450 3A4 catalyzes the metabolic clearance of a large number of... 
Protein Structure, Tertiary | Protein Structure, Secondary | Cytochrome P-450 CYP3A | Humans | Models, Molecular | Substrate Specificity | Crystallography, X-Ray | Microsomes - enzymology | Arginine - chemistry | Cytochrome P-450 Enzyme System - chemistry | Heme - chemistry | Protein Binding | Kinetics | Binding Sites
Journal Article
Journal Article
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 12/2014, Volume 86, Issue 6, pp. 665 - 674
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 04/2017, Volume 28, Issue 4, p. 885
Human cytochrome P450 3A4 (CYP3A4) is responsible for the metabolism of the majority of drugs. As such, it is implicated in many adverse drug-drug and... 
Cytochrome | Drugs | Cytochrome P450 | Metabolism | Coumarin | Substrates | Mutants | Molecules | Testosterone | Allosteric properties | Ligands | Oxidation | Mutation | Progesterone | Cooperativity | Kinetics | Enzyme kinetics | Pharmaceutical industry | Food
Journal Article