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Nature, ISSN 0028-0836, 04/2017, Volume 544, Issue 7649, pp. 235 - 239
Journal Article
Journal Article
American Journal of Epidemiology, ISSN 0002-9262, 04/2018, Volume 187, Issue 4, pp. 754 - 766
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2016, Volume 291, Issue 48, pp. 25255 - 25263
Journal Article
Journal Article
Diabetologia, ISSN 0012-186X, 6/2017, Volume 60, Issue 6, pp. 1066 - 1075
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 08/2016, Volume 44, Issue 8, pp. 1174 - 1179
Journal Article
Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 08/2016, Volume 119, Issue 2, pp. 173 - 183
Sunitinib ( SUN ) is a multi‐targeted tyrosine kinase inhibitor that was recently approved for the treatment of gastrointestinal tract and renal cancers. To... 
BREAST-CANCER | DIACYLGLYCEROL ACYLTRANSFERASE | TYROSINE KINASE INHIBITOR | RECEPTOR | PHARMACOLOGY & PHARMACY | TOXICOLOGY | INDUCTION | CYTOCHROME-P450 3A4 | DRUG TRANSPORT | PHASE-I | RENAL-CELL CARCINOMA | HEPATITIS-E | Cytochrome P-450 CYP1A1 - genetics | Cytochrome P-450 CYP1B1 - genetics | Liver - enzymology | Rats, Wistar | Kidney - enzymology | Aryl Hydrocarbon Hydroxylases - genetics | Transcriptome | Cytochrome P-450 Enzyme System - metabolism | Cytochrome P-450 CYP1B1 - metabolism | Male | Cytochrome P-450 CYP2E1 - genetics | Cytochrome P-450 CYP2E1 - metabolism | NAD(P)H Dehydrogenase (Quinone) - genetics | Steroid 16-alpha-Hydroxylase - metabolism | RNA, Messenger - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - metabolism | Glucuronosyltransferase - genetics | Glutathione Transferase - genetics | ATP-Binding Cassette Transporters - genetics | Liver - drug effects | Isoenzymes - metabolism | Cytochrome P-450 CYP1A2 - genetics | Lipid Peroxidation - drug effects | ATP-Binding Cassette Transporters - metabolism | Cytochrome P450 Family 2 - genetics | Indoles - pharmacology | Xenobiotics - metabolism | Steroid 16-alpha-Hydroxylase - antagonists & inhibitors | Cytochrome P450 Family 2 - antagonists & inhibitors | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Kidney - drug effects | Isoenzymes - genetics | RNA, Messenger - genetics | Glutathione Transferase - metabolism | Rats | Cytochrome P-450 CYP1A1 - metabolism | Cytochrome P-450 CYP1A2 - metabolism | Aryl Hydrocarbon Hydroxylases - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - genetics | Cytochrome P450 Family 4 - metabolism | Pyrroles - pharmacology | Animals | Cytochrome P450 Family 2 - metabolism | Glucuronosyltransferase - metabolism | Cytochrome P-450 Enzyme System - genetics | NAD(P)H Dehydrogenase (Quinone) - metabolism | Steroid 16-alpha-Hydroxylase - genetics | Cytochrome P450 Family 4 - genetics | Antimitotic agents | Enzymes | Antineoplastic agents | Liver | Proteins | Protein expression | Rodents | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2016, Volume 11, Issue 7, pp. e0159552 - e0159552
Hepatic drug metabolism by cytochrome P450 enzymes is altered by the nutritional status of patients. The expression of P450 enzymes is partly regulated by the... 
RAT | MULTIDISCIPLINARY SCIENCES | MOUSE | GENES | LIVER | ALPHA | MICE | EXPRESSION | MIDAZOLAM | Liver - enzymology | Metoprolol - pharmacology | Receptors, Cytoplasmic and Nuclear - deficiency | Omeprazole - blood | Cytochrome P-450 Enzyme System - metabolism | Warfarin - pharmacology | Cytochrome P-450 CYP3A - genetics | Liver - drug effects | Cytochrome P-450 CYP1A2 - genetics | Caffeine - pharmacology | Cytochrome P450 Family 2 - genetics | Female | Omeprazole - pharmacology | Membrane Proteins - metabolism | Metoprolol - blood | Fasting | Membrane Proteins - genetics | Caffeine - blood | Mice, Inbred C57BL | Gene Expression Regulation | Receptors, Cytoplasmic and Nuclear - genetics | Cytochrome P-450 CYP1A2 - metabolism | Mice, Knockout | Animals | Cytochrome P450 Family 2 - metabolism | Midazolam - blood | Cytochrome P-450 CYP3A - metabolism | Warfarin - blood | Cytochrome P-450 Enzyme System - genetics | Inactivation, Metabolic - genetics | Mice | Midazolam - pharmacology | Omeprazole | RNA | Analysis | Cytochrome P-450 | Drug metabolism | Dosage and administration | Research | Health aspects | Receptor analysis | Cytochrome | Drugs | Enzymes | Warfarin | Metoprolol | Liver | Cytochrome P450 | Homology | CYP1A2 protein | Metabolism | Gene expression | Alterations | Analgesics | Rodents | Pharmacy | Midazolam | CYP2D6 protein | Nutritional status | Caffeine | Index Medicus
Journal Article