X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (60976) 60976
Book Review (7048) 7048
Newsletter (5855) 5855
Publication (5082) 5082
Newspaper Article (1367) 1367
Book Chapter (667) 667
Dissertation (201) 201
Conference Proceeding (169) 169
Book / eBook (62) 62
Magazine Article (29) 29
Web Resource (23) 23
Trade Publication Article (14) 14
Data Set (11) 11
Government Document (11) 11
Reference (10) 10
Paper (7) 7
Streaming Video (7) 7
Transcript (2) 2
Presentation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (49762) 49762
humans (26851) 26851
animals (24570) 24570
male (18109) 18109
cytochrome p-450 (17976) 17976
cytochrome p-450 enzyme system - metabolism (16053) 16053
pharmacology & pharmacy (15902) 15902
cytochrome p450 (13485) 13485
female (12441) 12441
metabolism (11648) 11648
rats (10785) 10785
biochemistry & molecular biology (10418) 10418
enzymes (10134) 10134
cytochrome p-450 enzyme system - genetics (8924) 8924
toxicology (8697) 8697
research (8234) 8234
physiological aspects (7962) 7962
analysis (6870) 6870
expression (6348) 6348
liver (6300) 6300
cytochrome (6254) 6254
mice (5794) 5794
adult (5784) 5784
middle aged (5115) 5115
pharmacokinetics (4940) 4940
microsomes, liver - enzymology (4831) 4831
gene expression (4687) 4687
metabolites (4372) 4372
genetic aspects (4324) 4324
proteins (4278) 4278
liver - enzymology (4200) 4200
drug interactions (4147) 4147
genotype (4129) 4129
in-vitro (4095) 4095
genes (4044) 4044
hydroxylation (4021) 4021
kinetics (3948) 3948
induction (3849) 3849
cytochrome-p450 (3748) 3748
liver - drug effects (3637) 3637
cancer (3524) 3524
liver - metabolism (3509) 3509
microsomes, liver - metabolism (3469) 3469
molecular sequence data (3393) 3393
rats, sprague-dawley (3360) 3360
cytochrome p-450 enzyme inhibitors (3299) 3299
dose-response relationship, drug (3289) 3289
biotransformation (3264) 3264
inhibition (3182) 3182
aged (3146) 3146
oxidation-reduction (3064) 3064
identification (3004) 3004
article (2979) 2979
microsomes, liver - drug effects (2961) 2961
cytochrome p-450 enzyme system - biosynthesis (2887) 2887
cytochrome p-450 enzyme system - chemistry (2882) 2882
cytochrome p-450 cyp3a (2836) 2836
oxidative stress (2817) 2817
oncology (2800) 2800
pharmacogenetics (2794) 2794
enzyme inhibitors - pharmacology (2731) 2731
polymorphism, genetic (2724) 2724
toxicity (2678) 2678
amino acid sequence (2657) 2657
reports (2559) 2559
oxidation (2552) 2552
cells, cultured (2533) 2533
drugs (2499) 2499
gene-expression (2468) 2468
aryl hydrocarbon hydroxylases - genetics (2441) 2441
universities and colleges (2425) 2425
substrate specificity (2392) 2392
polymorphism (2355) 2355
cytochromes p450 (2347) 2347
cell biology (2324) 2324
base sequence (2296) 2296
biophysics (2294) 2294
mixed function oxygenases - metabolism (2260) 2260
endocrinology & metabolism (2250) 2250
human liver-microsomes (2234) 2234
aryl hydrocarbon hydroxylases (2227) 2227
rat (2220) 2220
biosynthesis (2219) 2219
environmental sciences (2214) 2214
health aspects (2204) 2204
chemistry, medicinal (2197) 2197
genetic research (2188) 2188
pharmacology (2171) 2171
rna, messenger - metabolism (2144) 2144
in vitro techniques (2133) 2133
mutation (2104) 2104
rats, wistar (2087) 2087
aryl hydrocarbon hydroxylases - metabolism (2078) 2078
chemistry, multidisciplinary (2070) 2070
activation (2069) 2069
biotechnology & applied microbiology (2022) 2022
cytochrome p-450 cyp1a1 - metabolism (2012) 2012
research article (2004) 2004
drug metabolism (1999) 1999
catalysis (1984) 1984
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (36) 36
Online Resources - Online (19) 19
Collection Dvlpm't (Acquisitions) - Vendor file (5) 5
Collection Dvlpm't (Acquisitions) - Closed Orders (3) 3
Chemistry (A D Allen) - Stacks (2) 2
UTL at Downsview - May be requested (1) 1
UofT at Scarborough - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (67874) 67874
Japanese (230) 230
Chinese (219) 219
Russian (154) 154
German (142) 142
French (141) 141
Spanish (61) 61
Korean (42) 42
Polish (38) 38
Portuguese (17) 17
Dutch (14) 14
Czech (12) 12
Hungarian (11) 11
Turkish (8) 8
Ukrainian (6) 6
Croatian (5) 5
Danish (5) 5
Bulgarian (4) 4
Italian (4) 4
Norwegian (4) 4
Swedish (4) 4
Greek (2) 2
Slovak (2) 2
Afrikaans (1) 1
Finnish (1) 1
Hebrew (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


ACS Catalysis, ISSN 2155-5435, 04/2012, Volume 2, Issue 4, pp. 647 - 666
Journal Article
BBA - General Subjects, ISSN 0304-4165, 2007, Volume 1770, Issue 3, pp. 314 - 329
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2010, Volume 285, Issue 43, pp. 32720 - 32733
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) protect against cardiovascular disease by largely unknown mechanisms. We tested the hypothesis that... 
Cytochrome P450 | Hydroxylase | Epoxygenase Pathway | Lipids | Eicosapentaenoic Acid (EPA) | Eicosanoids Biosynthesis | Enzymology | Arachidonic Acid | Docosahexaenoic Acid
Journal Article
Journal Article
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 08/2013, Volume 52, Issue 35, pp. 9309 - 9312
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 01/2010, Volume 38, Issue 1, pp. 92 - 99
The aim of the current study is to identify the human cytochrome P450 (P450) isoforms involved in the two oxidative steps in the bioactivation of clopidogrel... 
MECHANISM-BASED INHIBITION | ANTIAGGREGATING ACTIVITY | POLYMORPHISMS | TICLOPIDINE | PHARMACOKINETICS | HEALTHY-SUBJECTS | PHARMACOLOGY & PHARMACY | PRASUGREL | PHARMACODYNAMICS | MONOCLONAL-ANTIBODIES | ATORVASTATIN | Microsomes - metabolism | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Cytochrome P-450 Enzyme System - metabolism | Sulfaphenazole - pharmacology | Microsomes - drug effects | Cytochrome P-450 CYP3A - genetics | Cytochrome P-450 CYP1A2 - genetics | Antibodies - immunology | Omeprazole - pharmacology | Microsomes, Liver - enzymology | Platelet Aggregation Inhibitors - pharmacokinetics | Ticlopidine - pharmacokinetics | Oxidoreductases, N-Demethylating - metabolism | Aryl Hydrocarbon Hydroxylases - immunology | Oxidation-Reduction | Enzyme Inhibitors - pharmacology | Ticlopidine - analogs & derivatives | Oxidoreductases, N-Demethylating - immunology | Cytochrome P-450 CYP3A - metabolism | Cell Line, Tumor | Cytochrome P-450 Enzyme System - genetics | Theophylline - pharmacology | Kinetics | Cytochrome P-450 CYP2C9 | Theophylline - analogs & derivatives | Oxidoreductases, N-Demethylating - genetics | Glutathione - metabolism | Ketoconazole - pharmacology | Biotransformation - physiology | Cytochrome P-450 CYP1A2 Inhibitors | Microsomes, Liver - drug effects | Ticlopidine - metabolism | NADP - metabolism | Platelet Aggregation Inhibitors - metabolism | Cytochrome P-450 CYP3A - immunology | Cell Line | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Cytochrome P-450 CYP1A2 - immunology | Biocatalysis | Mephenytoin - analogs & derivatives | Cytochrome P-450 CYP1A2 - metabolism | Aryl Hydrocarbon Hydroxylases - metabolism | Mephenytoin - pharmacology | Antibodies - pharmacology | Cytochrome P-450 CYP3A Inhibitors | Cytochrome P-450 CYP2C19 | Clopidogrel | Cytochrome P-450 CYP2B6 | Index Medicus
Journal Article
Naunyn - Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 09/2019, pp. 1 - 11
Major metabolites of alpha-asarone in liver microsomes are epoxide-derived side-chain diols. The intermediately formed epoxides are mutagenic and form DNA... 
Cytochrome | Metabolic rate | Enzymes | Hydroxylation | Incubation | Liver | Cytochrome P450 | Asarones | Chains | Metabolism | Microsomes | Substrates | Demethylation | Carcinogens | Metabolites | Epoxidation | Metabolic activation | DNA adducts | Epoxides | Diols | Deoxyribonucleic acid--DNA | Adducts | Cytochromes P450 | Index Medicus
Journal Article
Conference Proceeding