Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (5133) 5133
Book Review (1183) 1183
Publication (616) 616
Book Chapter (61) 61
Book / eBook (27) 27
Conference Proceeding (20) 20
Newspaper Article (7) 7
Dissertation (6) 6
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (4815) 4815
humans (3274) 3274
animals (3145) 3145
cytokines (2327) 2327
mice (1794) 1794
signal transduction (1385) 1385
immunology (1141) 1141
cell biology (1094) 1094
male (1080) 1080
interleukin-6 (1068) 1068
inflammation (1025) 1025
female (1014) 1014
biochemistry & molecular biology (970) 970
interleukin-6 - metabolism (911) 911
expression (902) 902
cytokines - metabolism (853) 853
leukemia inhibitory factor (822) 822
cells, cultured (748) 748
cytokine (699) 699
gene expression (687) 687
gp130 (654) 654
phosphorylation (644) 644
cytokine receptor gp130 (635) 635
stat3 transcription factor - metabolism (634) 634
proteins (599) 599
activation (585) 585
rats (568) 568
interleukins (557) 557
research (542) 542
cells (522) 522
neurosciences (514) 514
il-6 (503) 503
rodents (501) 501
receptor (492) 492
mice, inbred c57bl (490) 490
cell line (473) 473
cytokine receptor gp130 - metabolism (466) 466
analysis (437) 437
interleukin-6 - pharmacology (437) 437
gene-expression (435) 435
membrane glycoproteins - metabolism (430) 430
interleukin 6 (428) 428
physiological aspects (427) 427
cancer (424) 424
tumor-necrosis-factor (422) 422
research article (420) 420
signal transduction - physiology (420) 420
multidisciplinary sciences (417) 417
oncology (416) 416
apoptosis (406) 406
signal transduction - drug effects (403) 403
adult (401) 401
dna-binding proteins - metabolism (395) 395
in-vivo (395) 395
article (393) 393
interleukin-6 - genetics (393) 393
stat3 (392) 392
kinases (387) 387
antigens, cd - metabolism (382) 382
mice, knockout (380) 380
ciliary neurotrophic factor (373) 373
medicine (367) 367
trans-activators - metabolism (361) 361
health aspects (358) 358
rna, messenger - metabolism (354) 354
abridged index medicus (353) 353
endocrinology & metabolism (353) 353
middle aged (353) 353
in-vitro (350) 350
stat3 transcription factor (341) 341
differentiation (339) 339
receptors, interleukin-6 - metabolism (337) 337
receptors, cytokine - metabolism (327) 327
necrosis-factor-alpha (326) 326
disease models, animal (325) 325
nf-kappa-b (318) 318
physiology (313) 313
molecular sequence data (297) 297
science (287) 287
cell line, tumor (281) 281
biology (278) 278
cytokines - genetics (267) 267
genetic aspects (265) 265
hematology (265) 265
cell proliferation (262) 262
gene expression regulation (262) 262
protein binding (253) 253
immune system (250) 250
suppressor of cytokine signaling 3 protein (250) 250
reverse transcriptase polymerase chain reaction (248) 248
disease (247) 247
immunohistochemistry (247) 247
oncostatin m (247) 247
cell differentiation (245) 245
tumor cells, cultured (245) 245
growth-factor (244) 244
amino acid sequence (242) 242
receptors (242) 242
aged (241) 241
leukemia (240) 240
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (5164) 5164
Chinese (9) 9
Spanish (6) 6
Polish (3) 3
Russian (3) 3
French (2) 2
German (2) 2
Japanese (2) 2
Czech (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text A gp130-Src-YAP module links inflammation to epithelial regeneration
by Taniguchi, Koji and Wu, Li-Wha and Grivennikov, Sergei I and De Jong, Petrus R and Lian, Ian and Yu, Fa-Xing and Wang, Kepeng and Ho, Samuel B and Boland, Brigid S and Chang, John T and Sandborn, William J and Hardiman, Gary and Raz, Eyal and Maehara, Yoshihiko and Yoshimura, Akihiko and Zucman-Rossi, Jessica and Guan, Kun-Liang and Karin, Michael
Nature, ISSN 0028-0836, 03/2015, Volume 519, Issue 7541, pp. 57 - 62
Inflammation promotes regeneration of injured tissues through poorly understood mechanisms, some of which involve interleukin (IL)-6 family members, the... 
PROGENITOR CELLS | IN-VITRO | STEM-CELLS | ACTIVATION | MULTIDISCIPLINARY SCIENCES | STAT3 | HIPPO PATHWAY | INTESTINAL REGENERATION | YAP | NF-KAPPA-B | CANCER | Inflammation - pathology | Up-Regulation | Intestinal Mucosa - metabolism | Body Weight | Cell Proliferation | Epithelial Cells - metabolism | Receptors, Notch - metabolism | Humans | Homeostasis | Phosphoproteins - metabolism | Inflammatory Bowel Diseases - metabolism | Intestinal Mucosa - cytology | Inflammation - metabolism | Inflammatory Bowel Diseases - pathology | HEK293 Cells | Cell Differentiation | Epithelial Cells - cytology | Disease Models, Animal | Proto-Oncogene Proteins c-yes - metabolism | Cytokine Receptor gp130 - metabolism | Signal Transduction | Epithelial Cells - pathology | Regeneration | Animals | Proto-Oncogene Proteins pp60(c-src) - metabolism | Mice | Enzyme Activation | Adaptor Proteins, Signal Transducing - metabolism | Intestinal Mucosa - pathology | Cytokines | Epithelial cells | Analysis | Gastrointestinal diseases | Colorectal cancer | Research | Phosphotransferases | Signal transduction | Tissue | Cell growth | Phosphorylation | Rodents | Stem cells | Ligands | Kinases | Small intestine | Cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Cell-Intrinsic IL-27 and gp130 Cytokine Receptor Signaling Regulates Virus-Specific CD4+ T Cell Responses and Viral Control during Chronic Infection
by Harker, James A and Dolgoter, Aleksandr and Zuniga, Elina I
Immunity, ISSN 1074-7613, 09/2013, Volume 39, Issue 3, pp. 548 - 559
The outcome of chronic viral infections, which affect millions of people worldwide, is greatly dependent on CD4 T cells. Here we showed that T cell-specific... 
B-CELLS | TGF-BETA | HIV-INFECTION | IMMUNODEFICIENCY-VIRUS | INTERLEUKIN-10 RECEPTOR | HEPATITIS-C-VIRUS | IMMUNOLOGY | PERSISTENCE IN-VIVO | EXHAUSTION | FOLLICULAR HELPER-CELLS | PD-1 EXPRESSION | Lymphocytic choriomeningitis virus - immunology | CD8-Positive T-Lymphocytes - cytology | Lymphocytic Choriomeningitis - virology | Cytokine Receptor gp130 - metabolism | Cell Survival | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Lymphocytic Choriomeningitis - immunology | Mice, Knockout | CD4-Positive T-Lymphocytes - immunology | Animals | Mice | Interleukins - biosynthesis | Receptors, Cytokine - metabolism | Receptors, Interleukin-6 | CD8-Positive T-Lymphocytes - immunology | Receptors, Cytokine - genetics | Interleukin-27 - metabolism | Medical research | Hepatitis | T cell receptors | Rodents | Viral infections | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours
by Imbeaud, Sandrine and Rebouissou, Sandra and Zucman-Rossi, Jessica and Pilati, Camilla and Balabaud, Charles and Poussin, Karine and Amessou, Mohamed and Izard, Tina and Bioulac-Sage, Paulette and Couchy, Gabrielle
Nature, ISSN 0028-0836, 01/2009, Volume 457, Issue 7226, pp. 200 - 204
Inflammatory hepatocellular adenomas are benign liver tumours defined by the presence of inflammatory infiltrates and by the increased expression of... 
MUTANT MICE | COMPLEX | GASTRIC TUMORIGENESIS | CYTOKINE RECEPTOR | PROBE LEVEL | MULTIDISCIPLINARY SCIENCES | MOLECULAR-CLONING | INTERLEUKIN-6 | BINDING | IL-6 | SIGNAL TRANSDUCER | Inflammation - pathology | Cytokine Receptor gp130 - metabolism | Signal Transduction | Cytokine Receptor gp130 - genetics | Humans | Adenoma, Liver Cell - pathology | Gene Expression Regulation, Neoplastic | Gene Expression Profiling | Cell Line, Tumor | Inflammation - genetics | Interferons - metabolism | Interleukin-6 - metabolism | Adenoma, Liver Cell - genetics | STAT3 Transcription Factor - metabolism | Sequence Deletion - genetics | Immune response | Chromosome deletion | Cellular signal transduction | Regulation | Research | Tumors | Interleukin-6 | Proteins | Studies | Rodents | Kinases | Cells | Binding sites | Crystal structure | Index Medicus | Sequence Deletion | Hépatology and Gastroenterology | Cytokine Receptor gp130 | Interferons | Inflammation | oncogene | Life Sciences | mutation | Human health and pathology | hepatocellular adenoma | Adenoma, Liver Cell | STAT3 Transcription Factor | gp130 | heaptocellular carcinoma | pathology | genetics | metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation
by Calon, Alexandre and Espinet, Elisa and Palomo-Ponce, Sergio and Tauriello, Daniele V.F and Iglesias, Mar and Céspedes, María Virtudes and Sevillano, Marta and Nadal, Cristina and Jung, Peter and Zhang, Xiang H.-F and Byrom, Daniel and Riera, Antoni and Rossell, David and Mangues, Ramón and Massagué, Joan and Sancho, Elena and Batlle, Eduard
Cancer Cell, ISSN 1535-6108, 11/2012, Volume 22, Issue 5, pp. 571 - 584
A large proportion of colorectal cancers (CRCs) display mutational inactivation of the TGF-β pathway, yet, paradoxically, they are characterized by elevated... 
BREAST-CANCER | NUDE-MICE | ONCOLOGY | POOR-PROGNOSIS | COLON-CARCINOMA-CELLS | TUMOR-SUPPRESSOR | RECEPTOR | GROWTH-FACTOR | BONE | LIVER METASTASIS | T-CELLS | CELL BIOLOGY | Recurrence | Interleukin-11 - physiology | Cytokine Receptor gp130 - genetics | Stromal Cells - pathology | Humans | Tumor Microenvironment | Cytokine Receptor gp130 - physiology | STAT3 Transcription Factor - physiology | Neoplasm Metastasis - drug therapy | Colorectal Neoplasms - drug therapy | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Tumor Cells, Cultured | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Cytokine Receptor gp130 - metabolism | Signal Transduction | Stromal Cells - metabolism | Transforming Growth Factor beta - physiology | Interleukin-11 - genetics | Interleukin-11 - metabolism | HT29 Cells | Animals | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Transforming Growth Factor beta - genetics | Mice | Colorectal Neoplasms - pathology | Transforming Growth Factor beta - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor α/WSX-1/gp130
by Hashimoto, Yuichi and Kurita, Megumi and Aiso, Sadakazu and Nishimoto, Ikuo and Matsuoka, Masaaki
Molecular Biology of the Cell, ISSN 1059-1524, 06/2009, Volume 20, Issue 12, pp. 2864 - 2873
Humanin (HN) inhibits neuronal death induced by various Alzheimer's disease (AD)-related insults via an unknown receptor on cell membranes. Our earlier study... 
APOPTOSIS | DISEASE-RELEVANT INSULTS | IN-VITRO | MEDIATED NEUROPROTECTION | ALZHEIMERS-DISEASE | MEMORY IMPAIRMENT | AMYLOID PRECURSOR PROTEIN | BETA PEPTIDES | HIPPOCAMPAL-NEURONS | NEUROTOXICITY | CELL BIOLOGY | Intracellular Signaling Peptides and Proteins - pharmacology | Cell Line | Cytokine Receptor gp130 - metabolism | Humans | Rats | Neurons - cytology | Protein Subunits - metabolism | Gene Knockdown Techniques | Receptors, Interleukin - metabolism | Animals | Protein Binding - drug effects | Cytoprotection - drug effects | Mice | Cell Death - drug effects | Neurons - drug effects | Ciliary Neurotrophic Factor Receptor alpha Subunit - metabolism | STAT3 Transcription Factor - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL‐6/gp130/STAT3 Pathway
by Hossain, Anwar and Gumin, Joy and Gao, Feng and Figueroa, Javier and Shinojima, Naoki and Takezaki, Tatsuya and Priebe, Waldemar and Villarreal, Diana and Kang, Seok‐Gu and Joyce, Celine and Sulman, Erik and Wang, Qianghu and Marini, Frank C and Andreeff, Michael and Colman, Howard and Lang, Frederick F
STEM CELLS, ISSN 1066-5099, 08/2015, Volume 33, Issue 8, pp. 2400 - 2415
Although mesenchymal stem cells (MSCs) have been implicated as stromal components of several cancers, their ultimate contribution to tumorigenesis and their... 
Brain tumor | Glioma stem cells | Interleukin‐6 | Glioblastoma | STAT3 | Mesenchymal stem cells | Interleukin-6 | PROGENITORS | SELF-RENEWAL | IDENTIFICATION | HUMAN GASTRIC-CANCER | CELL & TISSUE ENGINEERING | CELL BIOLOGY | GENOMIC INSTABILITY | BRAIN-TUMOR | MICROENVIRONMENT | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | STROMA | TISSUES | HEMATOLOGY | CARCINOMA | Cell Proliferation | Cytokine Receptor gp130 - metabolism | Signal Transduction | Glioma - pathology | Humans | Mesenchymal Stromal Cells - metabolism | Female | Male | Mesenchymal Stromal Cells - pathology | Interleukin-6 - metabolism | STAT3 Transcription Factor - metabolism | Glioma - metabolism | Bone marrow | Stem cells | Index Medicus | Brain Tumor
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text The gp130 Cytokine Interleukin‐11 Regulates Engraftment of Vav1–/– Hematopoietic Stem and Progenitor Cells in Lethally Irradiated Recipients
by De Vita, Serena and Li, Yanhua and Harris, Chad E and McGuinness, Meaghan K and Ma, Clement and Williams, David A
STEM CELLS, ISSN 1066-5099, 03/2018, Volume 36, Issue 3, pp. 446 - 457
During bone marrow transplantation, hematopoietic stem and progenitor cells (HSPCs) respond to signals from the hematopoietic microenvironment by coordinately... 
Hematopoietic progenitors | Hematopoiesis | Hematopoietic stem cells | Stem cells | EXCHANGE FACTOR | ACTIVATION | CYTOSKELETON | BONE-MARROW | RECEPTOR | PROLIFERATION | VAV1 | TRANSPLANTATION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | RHO GTPASES | HEMATOLOGY | Proto-Oncogene Proteins c-vav - genetics | Cytokine Receptor gp130 - metabolism | Cell Proliferation - physiology | Hematopoiesis - genetics | Hematopoietic Stem Cells - metabolism | Stem Cells - metabolism | Interleukin-11 - pharmacology | Hematopoiesis - drug effects | Animals | Stem Cells - drug effects | Stem Cells - physiology | Cell Proliferation - drug effects | Mice | Proto-Oncogene Proteins c-vav - metabolism | Bone marrow | Transplantation | G proteins | Interleukins | Cytokines | Fetuses | Interleukin | Radiation | Bone marrow transplantation | Irradiated | Stem cell transplantation | Ontogeny | Inflammation | Tissues | Progenitor cells | Hemopoiesis | Allografts | Pathways | Clonal deletion | Cells (biology) | Deletion | Irradiation | Glycoprotein gp130 | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling
by Zhu, Hong-Jian and Inglese, Melissa and Waring, Paul and Jones, Simon A and Giraud, Andrew S and Grail, Dianne and Najdovska, Meri and Jenkins, Brendan J and Baumann, Heinz and Nheu, Thao and Judd, Louise M and Topley, Nicholas and Boussioutas, Alex and Wang, Bo and Ernst, Matthias and McLoughlin, Rachel M
Nature Medicine, ISSN 1078-8956, 08/2005, Volume 11, Issue 8, pp. 845 - 852
The latent transcription factor Stat3 is activated by gp130, the common receptor for the interleukin (IL)-6 cytokine family and other growth factor and... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYTOKINE | NECK-CANCER | IL-6 | SMAD7 | CELL BIOLOGY | INHIBITION | GENE | IN-VIVO | GROWTH-FACTOR | EXPRESSION | Cytokine Receptor gp130 - metabolism | Cytokine Receptor gp130 - genetics | Stomach Neoplasms - metabolism | Immunoblotting | Reverse Transcriptase Polymerase Chain Reaction | Stomach Neoplasms - physiopathology | Adenoma - metabolism | Adenoma - physiopathology | Animals | Histological Techniques | Mice, Mutant Strains | Signal Transduction - physiology | Mice | Transcriptional Activation - physiology | Transforming Growth Factor beta - metabolism | STAT3 Transcription Factor - metabolism | Smad7 Protein - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text An Interleukin-6 Receptor-dependent Molecular Switch Mediates Signal Transduction of the IL-27 Cytokine Subunit p28 (IL-30) via a gp130 Protein Receptor Homodimer
by Garbers, C and Spudy, B and Aparicio-Siegmund, S and Waetzig, GH and Sommer, J and Holscher, C and Rose-John, S and Grotzinger, J and Lorenzen, I and Scheller, J
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 02/2013, Volume 288, Issue 6, pp. 4346 - 4354
IL-27 consists of the cytokine subunit p28 and the non-signaling alpha-receptor EBI3. p28 was shown to additionally act via the non-signaling membrane-bound... 
WSX-1 | COMPLEX | INHIBITION | ANTAGONIST | BIOCHEMISTRY & MOLECULAR BIOLOGY | CILIARY NEUROTROPHIC FACTOR | BINDING | NIH 3T3 Cells | Cytokine Receptor gp130 - metabolism | Cytokine Receptor gp130 - genetics | Humans | Cercopithecus aethiops | Receptors, Interleukin - genetics | Interleukins - metabolism | Receptors, Interleukin - metabolism | Interleukins - genetics | Animals | Protein Multimerization - physiology | Signal Transduction - physiology | Mice | Receptors, Cytokine - metabolism | COS Cells | Receptors, Cytokine - genetics | Index Medicus | Receptors | Signal Transduction | Interleukin | Cytokine | STAT3
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Bazedoxifene as a novel GP130 inhibitor for pancreatic cancer therapy
by Wu, Xiaojuan and Cao, Yang and Xiao, Hui and Li, Chenglong and Lin, Jiayuh
Molecular Cancer Therapeutics, ISSN 1535-7163, 11/2016, Volume 15, Issue 11, pp. 2609 - 2619
The IL6/GP130/STAT3 pathway is crucial for tumorigenesis in multiple cancer types, including pancreatic cancer, and presents as a viable target for cancer... 
INTERLEUKIN-6 IL-6 | ACTIVATOR | CARCINOMA CELLS | ONCOLOGY | ADENOCARCINOMA | STAT3 | CYTOKINE | ESTROGEN-RECEPTOR MODULATOR | OVARIAN-CANCER | TUMOR-GROWTH | TUMORIGENESIS | Phosphorylation | Pancreatic Neoplasms - metabolism | Apoptosis - drug effects | Humans | Molecular Conformation | STAT Transcription Factors - metabolism | Bone Density Conservation Agents | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Disease Models, Animal | Cell Survival - drug effects | Cytokine Receptor gp130 - metabolism | Cytokines - metabolism | Cytokine Receptor gp130 - chemistry | Pancreatic Neoplasms - pathology | Models, Molecular | Antineoplastic Agents - chemistry | Xenograft Model Antitumor Assays | Animals | Cytokine Receptor gp130 - antagonists & inhibitors | Selective Estrogen Receptor Modulators | Signal Transduction - drug effects | Cell Line, Tumor | Protein Binding | Mice | Indoles - chemistry | Index Medicus | Bazedoxifene | GP130 | STAT3 phosphylation | Pancreatic Cancer | Drug resistance | IL-6
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Müller glial cells
by Kun Do Rhee and Steven Nusinowitz and Kevin Chao and Fei Yu and Dean Bok and Xian-Jie Yang
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 11/2013, Volume 110, Issue 47, pp. E4520 - E4529
Ciliary neurotrophic factor (CNTF) acts as a potent neuroprotective agent in multiple retinal degeneration animal models. Recently, CNTF has been evaluated in... 
RETINAL GANGLION-CELLS | ROD PHOTORECEPTORS | SIGNALING PATHWAYS | NEURONAL DEATH | MULTIDISCIPLINARY SCIENCES | GROWTH-FACTORS | CILIARY NEUROTROPHIC FACTOR | LIGHT-INDUCED DEGENERATION | UP-REGULATION | INTRAOCULAR IMPLANTS | TRANSGENIC MICE | Immunohistochemistry | Microscopy, Electron, Transmission | Cytokine Receptor gp130 - metabolism | Enzyme-Linked Immunosorbent Assay | Retinal Degeneration - drug therapy | Retinal Degeneration - genetics | Humans | Ependymoglial Cells - metabolism | Mice, Transgenic | Lentivirus | Blotting, Western | Ciliary Neurotrophic Factor - metabolism | Animals | Flow Cytometry | Analysis of Variance | Signal Transduction - physiology | Mice | Photoreceptor Cells, Vertebrate - metabolism | Real-Time Polymerase Chain Reaction | Macular degeneration | Survival analysis | Cytokines | Neurons | Rodents | T cell receptors | Gene expression | Index Medicus | PNAS Plus | Biological Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights