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Nature, ISSN 0028-0836, 2013, Volume 504, Issue 7479, pp. 248 - 253
Achieving the goal of malaria elimination will depend on targeting Plasmodium pathways essential across all life stages. Here we identify a lipid kinase,... 
YEAST | TRANSMISSION | POTENT | VIVAX | PHOSPHATIDYLINOSITOL 4-PHOSPHATE | FALCIPARUM | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | KINASE | ZINC-FINGER NUCLEASES | SACCHAROMYCES-CEREVISIAE | Plasmodium - enzymology | Phosphatidylinositol Phosphates - metabolism | Humans | Male | rab GTP-Binding Proteins - genetics | Macaca mulatta | Plasmodium - drug effects | Hepatocytes - parasitology | 1-Phosphatidylinositol 4-Kinase - metabolism | Quinoxalines - pharmacology | Schizonts - cytology | Adenosine Triphosphate - metabolism | Plasmodium - growth & development | Female | Binding Sites | Fatty Acids - metabolism | Cytokinesis - drug effects | Imidazoles - metabolism | Life Cycle Stages - drug effects | Pyrazoles - pharmacology | 1-Phosphatidylinositol 4-Kinase - genetics | rab GTP-Binding Proteins - metabolism | 1-Phosphatidylinositol 4-Kinase - chemistry | Reproducibility of Results | Models, Molecular | 1-Phosphatidylinositol 4-Kinase - antagonists & inhibitors | Drug Resistance - drug effects | Imidazoles - pharmacology | Quinoxalines - metabolism | Pyrazoles - metabolism | Schizonts - drug effects | Drug Resistance - genetics | Animals | Models, Biological | Malaria - parasitology | Malaria - drug therapy | Plasmodium - classification | Plasma | Mosquitoes | Malaria | Licenses | Infections | Parasites | Kinases | Drug dosages | Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 4/2003, Volume 161, Issue 2, pp. 267 - 280
The Aurora/Ipl1 family of protein kinases plays multiple roles in mitosis and cytokinesis. Here, we describe ZM447439, a novel selective Aurora kinase... 
Mitotic index | Mitosis | Kinetochores | Microtubules | DNA | Cell lines | HeLa cells | Cultured cells | Chromosomes | Cells | Chemical biology | Aneuploidy | Spindle checkpoint | ZM447439 | KINASE-ACTIVITY | LOCALIZATION | BUDDING YEAST | PHOSPHORYLATION | TENSION | mitosis | MAMMALIAN-CELLS | CELL BIOLOGY | chemical biology | CENTROSOME AMPLIFICATION | HISTONE H3 | aneuploidy | spindle checkpoint | Protein Kinases - metabolism | Protein Kinases - genetics | Paclitaxel - pharmacology | DNA Replication - drug effects | Humans | Chromosome Segregation - drug effects | Mitosis - genetics | Tumor Suppressor Protein p53 - genetics | Aurora Kinase B | Spindle Apparatus - genetics | Eukaryotic Cells - ultrastructure | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Benzamides - pharmacology | Mad2 Proteins | Phosphorylation - drug effects | Calcium-Binding Proteins - metabolism | Eukaryotic Cells - enzymology | Chromosomal Proteins, Non-Histone - metabolism | Kinetochores - metabolism | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Repressor Proteins - genetics | Genes, cdc - drug effects | Aurora Kinases | Tumor Suppressor Protein p53 - drug effects | Anaphase - drug effects | Chromosomal Proteins, Non-Histone - genetics | Anaphase - genetics | Eukaryotic Cells - drug effects | Mitosis - drug effects | DNA Replication - genetics | Repressor Proteins - drug effects | Kinetochores - drug effects | Spindle Apparatus - drug effects | HeLa Cells | Quinazolines - pharmacology | Cell Cycle Proteins | Calcium-Binding Proteins - genetics | Chromosome Segregation - genetics | Research | Cytokinesis | Protein kinases | Proteins | Genes | Index Medicus | mitosis; spindle checkpoint; chemical biology; aneuploidy; ZM447439
Journal Article
New Phytologist, ISSN 0028-646X, 9/2015, Volume 207, Issue 4, pp. 1061 - 1074
Stress-activated plant mitogen-activated protein (MAP) kinase pathways play roles in growth adaptation to the environment by modulating cell division through... 
Proteins | Full Papers | Microtubules | Kinetochores | Antibodies | Cell division | Gene expression regulation | Signals | Arrows | Anaphase | Chromosomes | nitrosative stress | Arabidopsis | cell division | MPK | γ‐tubulin | microtubules | mitogen‐activated protein kinase | γ-tubulin | Mitogen-activated protein kinase | MPK6 | Nitrosative stress | EB1c | Tyrosine - pharmacology | Meristem - cytology | Telophase - drug effects | Arabidopsis - enzymology | Nitriles - pharmacology | Microtubule-Associated Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Chromosome Segregation - drug effects | Tyrosine - analogs & derivatives | Arabidopsis Proteins - metabolism | Microtubules - metabolism | Tubulin - metabolism | Spindle Apparatus - metabolism | Microtubules - drug effects | Meristem - metabolism | Stress, Physiological - drug effects | Meristem - drug effects | Phosphorylation - drug effects | Cytokinesis - drug effects | Butadienes - pharmacology | Arabidopsis - drug effects | Plant Cells - metabolism | Kinetochores - metabolism | Arabidopsis - cytology | Anaphase - drug effects | Nitrosation - drug effects | Plant Cells - drug effects | Cell Proliferation - drug effects | Kinetochores - drug effects | Spindle Apparatus - drug effects | Mitogen-Activated Protein Kinases - metabolism | Index Medicus
Journal Article
Journal Article
New Phytologist, ISSN 0028-646X, 9/2014, Volume 203, Issue 4, pp. 1175 - 1193
The role of YODA MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 4 (MAPKKK4) upstream of MITOGEN ACTIVATED PROTEIN KINASE 6 (MPK6) was studied during... 
Phosphates | Full papers | Dehydrogenases | Ribosomal proteins | Carrier proteins | Adenosine triphosphatases | Heat shock proteins | Trip chaining | Peptide elongation factors | Families | Chaperonins | MAPKKK | Arabidopsis | root | MPK | YODA | microtubules | MAP | 65‐1 | cell division plane | MAP65-1 | Root | Microtubules | Cell division plane | MPK6 | MICROTUBULE ARRAYS | SITE | STOMATAL DEVELOPMENT | MAP KINASE | FATE | PHRAGMOPLAST | PLANT SCIENCES | CYTOKINESIS | THALIANA | GROWTH | GENE FAMILY | Meristem - cytology | Arabidopsis - enzymology | Arabidopsis - embryology | Protein Transport - drug effects | Arabidopsis Proteins - metabolism | Microtubules - metabolism | Microtubules - drug effects | Protein Binding - drug effects | Plant Epidermis - cytology | Meristem - drug effects | Phosphorylation - drug effects | Cytokinesis - drug effects | Arabidopsis - drug effects | Indoleacetic Acids - metabolism | Interphase | Arabidopsis - cytology | MAP Kinase Kinase Kinases - metabolism | Plant Roots - cytology | Mutation - genetics | Cell Division - drug effects | Up-Regulation - drug effects | Phenotype | Mitosis - drug effects | Indoleacetic Acids - pharmacology | Plant Roots - embryology | Fluorescent Antibody Technique | Proteomics | Plant Roots - anatomy & histology | Mitogen-Activated Protein Kinases - metabolism | Arabidopsis thaliana | Cell division | Embryonic development | Mitogens | Protein kinases | Analysis | Index Medicus
Journal Article
The Plant Cell, ISSN 1040-4651, 9/2007, Volume 19, Issue 9, pp. 2763 - 2775
Controlling microtubule dynamics and spatial organization is a fundamental requirement of eukaryotic cell function. Members of the ORBIT/MAST/CLASP family of... 
Proteins | Dendritic cells | Microtubules | Epidermal cells | Plant roots | Fluorescence | Plants | Microtubule associated proteins | Animal cells | Plant cells | ROOT-CELLS | PLUS-END | BAND ORGANIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLANT-CELLS | MICROFILAMENT CROSS-TALK | PLANT SCIENCES | CELL BIOLOGY | CORTICAL MICROTUBULES | CELLULOSE MICROFIBRIL ALIGNMENT | MITOTIC SPINDLE | DYNAMICS | HELICAL GROWTH | Microtubule-Associated Proteins - chemistry | Microtubule-Associated Proteins - genetics | Dinitrobenzenes - pharmacology | Phylogeny | Plant Epidermis - ultrastructure | Recombinant Fusion Proteins - metabolism | Plant Roots - drug effects | Microtubules - metabolism | Microtubules - drug effects | Plant Epidermis - cytology | Plant Leaves - drug effects | Plant Roots - growth & development | Cytokinesis - drug effects | Protein Structure, Tertiary | Green Fluorescent Proteins - metabolism | Arabidopsis Proteins - genetics | Arabidopsis - drug effects | Arabidopsis - cytology | Cell Size - drug effects | Plant Roots - cytology | Plant Epidermis - drug effects | Mutation - genetics | Cell Division - drug effects | Plant Leaves - cytology | Arabidopsis - metabolism | Arabidopsis - genetics | Gene Expression Regulation, Plant - drug effects | Mitosis - drug effects | Arabidopsis Proteins - chemistry | Cell Proliferation - drug effects | Interphase - drug effects | Plant Leaves - ultrastructure | Sulfanilamides - pharmacology | Arabidopsis thaliana | Growth | Mitosis | Kinetochores | Genetic aspects | Research | Properties | Observations | Gene expression | Index Medicus
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2013, Volume 210, Issue 11, pp. 2371 - 2385
Journal Article